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2301 - 2350 of 10000+ citations for PD 1 Human C93S HEK293 His since 2019

• Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ

  Manuel Hayn, et al., bioRxiv - Microbiology 2020

  Quote: ... ULK1 (1:1,000, D8H5, Cell Signaling Technology), Rab5 (1:1,000 ...
• Alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel inhibits proliferation and migration of human liver cancer HepG2 cells

  Allisson B. Justino, et al., bioRxiv - Biochemistry 2021

  Quote: ... vinculin (mouse, 1:1,000, Cell Signaling Technology), epidermal growth factor receptor EGFR (mouse ...
• Immunoproteasome deficiency leads to sustained pancreatic injury and delayed recovery from experimental pancreatitis

  Laura L. De Freitas Chama, et al., bioRxiv - Physiology 2020

  Quote: ... anti-CHOP (1:2000; 2895, Cell Signaling) and anti-LC3 (1:2000 ...
• ErbB dysregulation impairs cognition via myelination-dependent and - independent oligodendropathy

  Xu Hu, et al., bioRxiv - Neuroscience 2020

  Quote: ... Ki67 (1:400, Cell Signaling Technology, 9129), GFAP (1:2000 ...
• A chemical screen identifies a link between lipid metabolism and mRNA translation

  Alba Corman, et al., bioRxiv - Molecular Biology 2020

  Quote: ... P70S6K (1:1000, Cell Signaling Technology, 9202S), 4E-BP1 (1:1000 ...
• A chemical screen identifies a link between lipid metabolism and mRNA translation

  Alba Corman, et al., bioRxiv - Molecular Biology 2020

  Quote: ... eIF2a (1:500, Cell Signaling Technology, 9722), Vinculin (EPR8185 ...
• Inositol Polyphosphate-5-phosphatase K (Inpp5k) enhances sprouting of corticospinal tract axons after CNS trauma

  Sierra D. Kauer, et al., bioRxiv - Neuroscience 2021

  Quote: ... Phospho-Cofilin (Ser3) (1:250, Cell Signaling), and EB3 (1:250 ...
• UCHL1 inhibited by A1 astrocytes facilitates aggregates clearance to promote neural stem cells activation after spinal cord injury

  Lu Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... NF200 (1:1000; Cell Signaling Technology, CST), MBP (1:1000 ...
• UCHL1 inhibited by A1 astrocytes facilitates aggregates clearance to promote neural stem cells activation after spinal cord injury

  Lu Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... Nestin (1:1000; Cell Signaling Technology, CST), GFAP (1:1000 ...
• UCHL1 inhibited by A1 astrocytes facilitates aggregates clearance to promote neural stem cells activation after spinal cord injury

  Lu Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... GFAP (1:1000; Cell Signaling Technology, CST), MAP2 (1:1000 ...
• UCHL1 inhibited by A1 astrocytes facilitates aggregates clearance to promote neural stem cells activation after spinal cord injury

  Lu Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... MBP (1:1000; Cell Signaling Technology, CST), nuclear related factor 2 (Nrf2 ...
• Sustained ErbB activation causes demyelination and hypomyelination by driving necroptosis of mature oligodendrocytes and apoptosis of oligodendrocyte precursor cells

  Xu Hu, et al., bioRxiv - Neuroscience 2021

  Quote: ... Akt (1:5000, Cell signaling Technology, 9272), pAkt (1:3000 ...
• Sustained ErbB activation causes demyelination and hypomyelination by driving necroptosis of mature oligodendrocytes and apoptosis of oligodendrocyte precursor cells

  Xu Hu, et al., bioRxiv - Neuroscience 2021

  Quote: ... pAkt (1:3000, Cell signaling Technology, 9271), Erk1/2 (1:5000 ...
• Angiocrine IGFBP3 Spatially Coordinates IGF Signaling During Neonatal Cardiac Regeneration

  Shah R. Ali, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Akt (Cell Signaling, 9272S, 1:1000), anti-phospho Akt (Thr308 ...
• SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human K_ATP-induced diabetes trough mitigation of oxidative and ER stress

  Zeenat A. Shyr, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-glucagon (Cell signaling, 1:100), rabbit anti-somatostatin (Abcam ...
• Multiple viral microRNAs regulate interferon release and signaling early during infection with Epstein-Barr virus

  Mickaël Bouvet, et al., bioRxiv - Microbiology 2020

  Quote: ... IRF-9 (Cell signaling, #28492, 1:1000), TLR7 (Abcam ...
• Direct therapeutic targeting of SWI/SNF induces epigenetic reprogramming and durable tumor regression in rhabdoid tumor

  Maggie H. Chasse, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Cleaved Caspase-3 (Cell Signaling, 1:250), H3K27ac (Abcam ...
• Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics

  Yang Gao, et al., bioRxiv - Cancer Biology 2021

  Quote: ... PLK2 (Cell Signaling Technology, 14821, 1:1000), and GAPDH (Cell Signaling Technology ...
• The protection of Gα_z-null NOD mice from hyperglycemia is sexually dimorphic and only partially β-cell autonomous

  Rachel J. Fenske, et al., bioRxiv - Physiology 2021

  Quote: ... rabbit anti-Ki67 (Cell Signaling - 1:200) and guinea-pig anti-insulin (Abcam - 1:75 ...
• Branched ubiquitin chain binding and deubiquitination by UCH37 facilitate proteasome clearance of stress-induced inclusions

  Aixin Song, et al., bioRxiv - Biochemistry 2021

  Quote: ... PSMB5 (Cell Signaling Technology 12919S, 1:1000); ubiquitin (P4D1 ...
• KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy

  Katrin Linda, et al., bioRxiv - Neuroscience 2020

  Quote: ... p-mTOR (1:1000; Cell Signaling 2971), GAPDH (1:1000 ...
• Lipidomic profiling of clinical prostate cancer reveals targetable alterations in membrane lipid composition

  Lisa M. Butler, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or pACC1 (Cell Signaling, 3661S; 1:400) was applied and slides incubated overnight at 4°C ...
• SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade

  Octavio A. Romero, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-EZH2 5246S (1:1000, Cell Signaling); anti-H3K27ac D5E4 (1:1000 ...
• SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade

  Octavio A. Romero, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-H3K27ac D5E4 (1:1000, Cell Signaling) anti-H3K27me3 07-449 (1:1000 ...
• RIOK2 drives glioblastoma cell proliferation by modulating MYC through the RNA-binding protein IMP3

  Alexander S. Chen, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and DRAQ7 (1:200, Cell Signaling Technology) to stain nuclear DNA and chromosomes.
• Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression

  Aziz Aiderus, et al., bioRxiv - Cancer Biology 2020

  Quote: ... phospho ERK (1:1000, Cell Signaling #4695), GAPDH (1:5000 ...
• Latent Plasticity of Effector-like Exhausted CD8 T cells contributes to memory responses

  Saravanan Raju, et al., bioRxiv - Immunology 2020

  Quote: ... Anti-TCF-1 antibody (Cell Signaling, C63D9) and detected by Alexa 488-conjugated Donkey anti-rabbit polyclonal IgG (Thermo Fisher ...
• Defective myelination in an RNA polymerase III mutant leukodystrophic mouse

  Emilio Merheb, et al., bioRxiv - Neuroscience 2021

  Quote: ... Caspase-3 (Cell Signaling 9662; 1:1000), Cleaved Caspase-3 (Cell Signaling 9664 ...
• The nuclear ubiquitin ligase adaptor SPOP is a conserved regulator of C9orf72 dipeptide toxicity

  Carley Snoznik, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-PTEN (1:1000; Cell Signaling Technology), anti-DUSP7 (1:1000 ...
• Sex-dependent effects of CYP46A1 overexpression on cognitive function during aging

  María Latorre-Leal, et al., bioRxiv - Animal Behavior and Cognition 2021

  Quote: ... phospho-CREB (Cell Signaling 86B10, 1:1000), ADAM 10 (Abcam ab1997 ...
• Sortilin exhibits tumor suppressor-like activity by limiting EGFR transducing function

  E. Lapeyronnie, et al., bioRxiv - Cancer Biology 2021

  Quote: ... AKT (#4691, 1:1000 dilution, Cell Signaling), lamin b1 (#HPA050524 ...
• Combinatorial Immunotherapies Overcome MYC-Driven Immune Evasion

  Joyce V. Lee, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-STAT1 (1:1,000, #9172, Cell Signaling), Anti-Rabbit IgG (1:10,000 ...
• MYC promotes immune-suppression in TNBC via inhibition of IFN signaling

  Dario Zimmerli, et al., bioRxiv - Cancer Biology 2021

  Quote: ... or cGAS (1:200, Cell Signaling, #15102) in PBS–Tween–BSA ...
• The Mammalian Target of Rapamycin (mTOR) Kinase Mediates Haloperidol-Induced Cataleptic Behavior

  Uri Nimrod Ramírez-Jarquín, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-mTOR (1:250, Cell Signaling, #2983), and anti-GFP (Santa Cruz ...
• mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex

  Madeline G. Andrews, et al., bioRxiv - Neuroscience 2020

  Quote: ... p4EBP1 (Cell Signaling Technology, 2855S, 1:500), DEPDC5 (Sigma ...
• Modeling human age-associated increase in Gadd45γ expression leads to spatial recognition memory impairments in young adult mice

  David V.C. Brito, et al., bioRxiv - Neuroscience 2020

  Quote: ... total-CREB (1:5000, Cell Signaling, #4820), β-Actin (1:1000 ...
• The canonical Wnt signaling pathway is not a promising therapeutic target for PNS regeneration enhancement

  Nikita Mehta, Maia Vardy, Benayahu Elbaz, bioRxiv - Neuroscience 2022

  Quote: ... p75NTR (Cell Signaling Technology, 8238T, 1:250) and MBP (BioRad ...
• 17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

  Samim Ali Mondal, et al., bioRxiv - Physiology 2022

  Quote: ... phospho-p65 (serine536; Cell Signaling; 1:1000), GAPDH (Abcam ...
• A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding

  Lei Wang, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1 μg/mL leupeptin (Cell Signaling, 9803s), and 1 mM PMSF ...
• Diminished motor neuron activity driven by abnormal astrocytic GLAST glutamate transporter activity in spinal muscular atrophy is not fully restored after lentiviral SMN delivery

  Emily Welby, Allison D. Ebert, bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-GFP (1:1000, Cell Signaling). Following 3x washes with 1x TBST ...
• Multiomic deep delve of synthesis and secretion processes in a model peptidergic system

  Soledad Bárez-López, et al., bioRxiv - Neuroscience 2022

  Quote: ... Synapsin (1:1000, Cell Signaling Technology, 2312S) and Tubulin (1:5000 ...
• N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity

  Sylvia Varland, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-CUL1 (Cell Signaling, 4995, 1:1000), anti-CUL2 (Abcam ...
• N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity

  Sylvia Varland, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-CUL3 (Cell Signaling, 2759, 1:1000), anti-CUL4A (Cell Signaling ...
• N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity

  Sylvia Varland, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-CUL4A (Cell Signaling, 2699, 1:1000), anti-CUL4B (Proteintech ...
• Hepatic MCPIP1 protein levels are reduced in NAFLD patients and are predominantly expressed in cholangiocytes and liver endothelium

  Natalia Pydyn, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-p-AktSer473 (1:1000; Cell Signaling), rabbit anti-IGF1R (1:1000 ...
• ID1 and CEBPA Coordinate Epidermal Progenitor Cell Differentiation

  Christina Geraldine Kantzer, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Cebpa (Cell Signaling Technology, #2295, 1:1000) phospho-Smad1/5 (Cell Signaling Technology ...
• ID1 and CEBPA Coordinate Epidermal Progenitor Cell Differentiation

  Christina Geraldine Kantzer, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Cebpa (Cell Signaling Technology, #2295, 1:500). Antibodies used for immunoblotting are listed below ...
• G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

  Ewa Bielczyk-Maczynska, et al., bioRxiv - Physiology 2022

  Quote: ... phospho-S6 (Cell Signaling, #2211, 1:1,000). Equal protein loading was verified using antibody against β-actin (Santa Cruz ...
• G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

  Ewa Bielczyk-Maczynska, et al., bioRxiv - Physiology 2022

  Quote: ... phospho-Akt (Cell Signaling, #4060, 1:1,000), S6 (Cell Signaling ...
• Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding

  Tamadher A. Alghamdi, et al., bioRxiv - Physiology 2022

  Quote: ... CD81 (dilution 1:1000; Cell Signaling 10037S), Aldh1a3 (dilution 1:1000 ...