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2301 - 2350 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• The IgG3 Subclass of β1-adrenergic receptor autoantibody is an endogenous biaser of β1AR signaling

  Maradumane L. Mohan, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... α-ERK (Cell Signaling, 1:2000), α-pβ2AR (Santacruz Biotechnology ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... eIF2α (1:1000, Cell Signaling), ATF4 (1:1000 ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... PARP (1:2000, Cell Signaling), LC3B (1:2000 ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... α-tubulin (1:2000, Cell Signaling), and β-actin (1:2500 ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... ATF4 (1:1000, Cell Signaling), TFEB (1:1000 ...
• PERK Activation by SB202190 Attenuates Amyloidogenesis via TFEB-induced Autophagy-Lysosomal Pathway

  Mihyang Do, et al., bioRxiv - Neuroscience 2021

  Quote: ... α-synuclein (1:2000, Cell Signaling), α-tubulin (1:2000 ...
• Temporally-precise basolateral amygdala activation is required for the formation of taste memories in gustatory cortex

  Elor Arieli, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1:1000 (Cell Signaling, 8889S) and with DAPI 1:1000 in block for 3h at room temperature ...
• Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD⁺ signaling

  Mustafa N. Okur, et al., bioRxiv - Cell Biology 2020

  Quote: ... Beclin-1 (Cell signaling, #3738), mitofusin 2 (Cell signaling ...
• Deletion of the AMPylase mFICD alters cytokine secretion and affects cognitive plasticity in vivo

  Nicholas McCaul, et al., bioRxiv - Molecular Biology 2021

  Quote: ... XBP-1 (Cell Signaling Technology), PERK (Santa Cruz) ...
• Argonaute Binding within Human Nuclear RNA and its Impact on Alternative Splicing

  Yongjun Chu, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1:1000 (2433, Cell Signaling), anti-LaminA/C ...
• Defining the RBPome of T helper cells to study higher order post-transcriptional gene regulation

  Kai P. Hoefig, et al., bioRxiv - Immunology 2020

  Quote: ... (1:1000, 8776, Cell Signaling), anti-β- tubulin ...
• Defining the RBPome of T helper cells to study higher order post-transcriptional gene regulation

  Kai P. Hoefig, et al., bioRxiv - Immunology 2020

  Quote: ... (1:1000, 86298, Cell Signaling). Proteins were visualized by staining with anti-rat (1:3000 ...
• GOLIATH regulates LDLR availability and plasma LDL cholesterol levels

  Bethan L. Clifford, et al., bioRxiv - Molecular Biology 2020

  Quote: ... PDI (1:1,000; Cell Signaling), and Transferrin Receptor (1:1,000 ...
• Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition

  Nezihi Murat Karabacak, et al., bioRxiv - Cancer Biology 2021

  Quote: ... pGSK3ß (Cell Signaling; 1:500), Total GSK3ß (Cell Signaling ...
• Argonaute Binding within 3’-Untranslated Regions Does Not Predict Gene Repression

  Yongjun Chu, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1:20000 (2650S, Cell Signaling).
• Argonaute Binding within 3’-Untranslated Regions Does Not Predict Gene Repression

  Yongjun Chu, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1:1000 (2433S, Cell Signaling), anti-LaminA/C ...
• HES1 is a Critical Mediator of the SHH-GLI3 Axis in Regulating Digit Number

  Deepika Sharma, et al., bioRxiv - Developmental Biology 2020

  Quote: ... CCND1 (1:1000; Cell Signaling), LMNA (1:1000 ...
• Mitochondrial dysfunction promotes alternative gasdermin D-mediated inflammatory cell death and susceptibility to infection

  Chi G. Weindel, et al., bioRxiv - Immunology 2021

  Quote: ... DRP1 (Cell Signaling, 1:1000); pDRP1 Ser616 (Cell Signaling ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... PDX1 (Cell Signaling 1:1000), BclXL (Cell Signaling 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... PTEN (Cell Signaling 1:1000), pAKT (Cell Signaling ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... BclXL (Cell Signaling 1:1000), HSP90 (Santa Cruz 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... p27 (Cell Signaling 1:1000), PTEN (Cell Signaling 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... pAKT (Cell Signaling, 1:1,000), AKT (Cell Signaling 1:1,000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... SKP2 (Cell Signaling 1:1000), p57 (Cell Signaling 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... p21 (Cell Signaling 1:1000), p27 (Cell Signaling 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... V5 (Cell Signaling 1:1000), SKP2 (Cell Signaling 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... p57 (Cell Signaling 1:1000), p16 INK4a (Cell Signaling 1:1000) ...
• Role of the G-Protein Coupled Receptor 3-Salt Inducible Kinase 2 Pathway in Human β Cell Proliferation

  Caterina Iorio, et al., bioRxiv - Cell Biology 2021

  Quote: ... AKT (Cell Signaling 1:1,000), p18 (Abcam 1:2000) ...
• Argonaute Binding within Human Nuclear RNA and its Impact on Alternative Splicing

  Yongjun Chu, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1:2000 (5053, Cell Signaling), anti-AGO2 ...
• PI3K/AKT signaling allows for MAPK/ERK pathway independency mediating dedifferentiation-driven treatment resistance in melanoma

  Eyleen Corrales, et al., bioRxiv - Cancer Biology 2022

  Quote: ... PTEN (1:1000; Cell Signaling). All membranes were probed with GAPDH (1:3333 ...
• PERK Signaling Promotes Mitochondrial Elongation By Remodeling Membrane Phosphatidic Acid

  Valerie Perea, et al., bioRxiv - Cell Biology 2022

  Quote: ... ATF4 (Cell Signaling, 1:500), Tubulin [B-5-1-2] (Sigma ...
• PIKfyve controls dendritic cell function and tumor immunity

  Jae Eun Choi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... TBK-1 (Cell Signaling: D1B4), vinculin (Sigma Aldrich ...
• The transmembrane protein Syndecan regulates stem cell nuclear properties and cell maintenance

  Buffy L. Eldridge-Thomas, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1/500 (Cell Signaling, 3724T); rabbit anti-H2Av ...
• Sarm1 is not necessary for activation of neuron-intrinsic growth programs yet required for the Schwann cell repair response and peripheral nerve regeneration

  Ligia B. Schmitd, et al., bioRxiv - Neuroscience 2024

  Quote: ... (1:200, Cell Signaling, 5297s); chicken anti-neuofilament H (1:1000 ...
• iSCORE-PD: an isogenic stem cell collection to research Parkinson’s Disease

  Oriol Busquets, et al., bioRxiv - Neuroscience 2024

  Quote: ... PU.1 (Cell Signaling Tech)) ...
• Unraveling LIS1-Lissencephaly: Insights from Cerebral Organoids Suggest Severity- Dependent Genotype-Phenotype Correlations, Molecular Mechanisms and Therapeutic Strategies

  Lea Zillich, et al., bioRxiv - Neuroscience 2024

  Quote: ... TUBB3 (1:2000, Cell Signaling), NANOG (1:200 ...
• Forward genetic screens identify mechanisms of resistance to small molecule lactate dehydrogenase inhibitors

  Anderson R Frank, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1:2,000 (Cell Signaling 2017); anti-LDHA ...
• Poly(ADP-ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation

  M Iqbal Hossain, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti–HK-1 (Cell Signaling) and anti-GFP (Cell Signaling ...
• Cellular protection from H₂O₂ toxicity by Fv-Hsp70. Protection via catalase and gamma-glutamyl cysteine synthase

  Chris Hino, et al., bioRxiv - Cell Biology 2023

  Quote: ... HO-1 (Cell Signaling 5853S), and polyclonal Nrf 2 (Cell Signaling 336495) ...
• Uptake-independent killing of macrophages by extracellular aggregates of Mycobacterium tuberculosis is ESX-1 and PDIM-dependent

  Chiara Toniolo, Neeraj Dhar, John D. McKinney, bioRxiv - Microbiology 2023

  Quote: ... cleaved Caspase-1 (Cell Signaling), phospho-RIP3 (Cell Signaling) ...
• Dysfunctional Mitochondria in Cardiac Fibers of a Williams-Beuren Syndrome Mouse Model

  Noura Abdalla, et al., bioRxiv - Molecular Biology 2023

  Quote: ... FIS1 (Cell signaling, 1:1000). Thereafter ...
• Dysfunctional Mitochondria in Cardiac Fibers of a Williams-Beuren Syndrome Mouse Model

  Noura Abdalla, et al., bioRxiv - Molecular Biology 2023

  Quote: ... MFN2 (Cell signaling, 1:1000), FIS1 (Cell signaling ...
• Dysfunctional Mitochondria in Cardiac Fibers of a Williams-Beuren Syndrome Mouse Model

  Noura Abdalla, et al., bioRxiv - Molecular Biology 2023

  Quote: ... MFN1 (Cell signaling, 1:1000), MFN2 (Cell signaling ...
• Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

  Maiko Matsui, et al., bioRxiv - Physiology 2023

  Quote: ... AMPK (1:1000, Cell Signaling), pAMPK (1:1000 ...
• Multiple beta cell-independent mechanisms drive hypoglycemia in Timothy syndrome

  Maiko Matsui, et al., bioRxiv - Physiology 2023

  Quote: ... pAMPK (1:1000, Cell Signaling), Vinculin ...
• YAP and TAZ differentially regulate postnatal cortical progenitor proliferation and astrocyte differentiation

  Jessie Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... pLATS1 (Cell Signaling, 1:1000), LATS1 (Cell Signaling ...
• Pharmacologic Activation of a Compensatory Integrated Stress Response Kinase Promotes Mitochondrial Remodeling in PERK-deficient Cells

  Valerie Perea, et al., bioRxiv - Cell Biology 2023

  Quote: ... PARP (Cell Signaling, 1:1000), GAPDH (Fisher ...
• Pharmacologic Activation of a Compensatory Integrated Stress Response Kinase Promotes Mitochondrial Remodeling in PERK-deficient Cells

  Valerie Perea, et al., bioRxiv - Cell Biology 2023

  Quote: ... OMA1 (Cell Signaling, 1:1000), beta-actin (Cell Signaling 1:5,000) ...
• Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targeting of WRN and ATR

  Dali Zong, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CHK2 (1:1000, Cell Signaling), β-actin (1:5000 ...
• Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targeting of WRN and ATR

  Dali Zong, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CHK1 (1:1000, Cell Signaling), pRPA2 (S33 ...