Labshake search

2051 - 2100 of 4577 citations for Mouse WAP kazal immunoglobulin kunitz and NTR domain containing protein 2 WFIKKN2 ELISA Kit since 2019

• Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target

  Lucas Caldi Gomes, et al., bioRxiv - Neuroscience 2024

  Quote: ... and rabbit anti Phospho-MEK1/2 (Ser217/221) (Cell Signaling Technology, Danvers ...
• Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target

  Lucas Caldi Gomes, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti Phospho-p44/42 MAPK(ERK1/2) (Cell Signaling Technology, Danvers ...
• Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice

  Lauren Podmore, et al., bioRxiv - Cancer Biology 2023

  Quote: ... phospho-p44/42 MAPK (Erk1/2) (T202/Y204) (Cell Signaling #9101), S6 (Cell Signaling #2217) ...
• EWS::FLI1-DHX9 interaction promotes Ewing sarcoma sensitivity to DNA topoisomerase 1 poisons by altering R-loop metabolism

  Joaquin Olmedo-Pelayo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... extracts were incubated with 2 µl Micrococcal Nuclease (Cell Signaling, 10011) and sonicated in a Bioruptor (Diagenode ...
• CRIPTO promotes extracellular vesicle uptake and activation of cancer associated fibroblasts

  David W. Freeman, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-ERK1/2 (Thr202/204) (Clone D13.144E, Cell Signaling, 1:1000), ERK1/2 (L34F12 ...
• A progesterone derivative linked to a stable phospholipid activates breast cancer cell response without leaving the cell membrane

  Jofre Font-Mateu, et al., bioRxiv - Genomics 2023

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling #9106S), HP1 gamma (Millipore 05-690).
• NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma

  Claudia Cirotti, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho-ERK 1/2 (Thr202/Tyr204) (D13.14.4E) (Cell Signaling Technology), anti-Ubiquitin (P4D1 ...
• Inhibition of Cellular MEK/ERK Signaling Suppresses Murine Papillomavirus Type 1 Replicative Activities and Promotes Tumor Regression

  Adrian J. Luna, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Immunohistochemical detection of p-ERK1/2 (Cell Signaling #4370; 1:500) required the tyramide signal amplification (TSA ...
• Actomyosin-II Proactively Shields Axons of the Central Nervous System from Mild Mechanical Stress

  Xiaorong Pan, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Phospho-Myosin Light Chain 2 (Thr18/Ser19) (Cell Signaling, #3674); anti-Myosin Light Chain 2 (Cell Signaling ...
• In Silico Transcriptome-based Screens Identify Epidermal Growth Factor Receptor Inhibitors as Therapeutics for Noise-induced Hearing Loss

  Sarath Vijayakumar, et al., bioRxiv - Neuroscience 2023

  Quote: ... phospho forms (AKT-S473 and ERK1/2-T202/Y204, Cell Signaling) and β-actin (Sigma A3854).
• Anti-apoptotic and anti-inflammatory properties of grapefruit IntegroPectin on human microglial HMC3 cell line

  Miriana Scordino, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-p-ERK1/2 (1:1000, 9101 Cell Signaling Technology), rabbit anti-p-Akt (1:1000 ...
• Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

  Jayne Aiken, Erika L. F. Holzbaur, bioRxiv - Cell Biology 2023

  Quote: ... and Synaptobrevin-2 (anti-rabbit; Cell Signaling; 13508; 1:250 dilution). Following three washes with PBS ...
• Secreted soluble factors from tumor-activated mesenchymal stromal cells confer platinum chemoresistance to ovarian cancer cells

  Yifat Koren Carmi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-phospho-ERK1/2 (Thr202/Tyr204) (D13.14.4E, Cell Signaling Technology) as per the manufacturers’ instructions ...
• EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis

  Sukanya Chakraborty, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho-ERK1/2-Thr202/Tyr204 (#9101) from Cell Signaling Technology; and anti-beta-actin (#A5441 ...
• Oncogenic Kras^G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8⁺ T cells dependent manner

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Cell Signaling 4376S, 1:1000) and Vinculin (Abcam ab129002 ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p44/42 MAPK (ERK1/2) (Cell Signaling Technology, 4695S, 1:1,000), p-p44/42 MAPK (pERK1/2 ...
• Differential LRRK2 signalling and gene expression in WT-LRRK2 and G2019S-LRRK2 mouse microglia treated with zymosan and MLi2

  Iqra Nazish, et al., bioRxiv - Neuroscience 2023

  Quote: ... and anti-4′,6-diamidino-2-phenylindole (DAPI) (Cell Signaling #4083). The primary microglial yield was approximately 5 × 105 cells/flask with minimal astrocyte contamination ...
• HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

  Hongbo Ling, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho-ERK1/2 (Thr202/Tyr204) (Cell Signaling Technology, #9101, RRID:AB_331646), anti-ERK1/2 (Cell Signaling Technology ...
• Ascites in malignant ovarian cancer confer ovarian cancer cells chemoresistance to platinum. Combination treatment with crizotinib and 2-hydroxyestradiol restores platinum sensitivity

  Yifat Koren Carmi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-phospho-ERK1/2 (Thr202/Tyr204) (D13.14.4E, Cell Signaling Technology) according to the manufacturers’ instructions ...
• Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium

  Anagha Inguva Sheth, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Primary antibodies used include BCL-2 (Cell Signaling Technologies, no.15071), SERCA3 (Biorad ...
• Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations

  Maria Victoria Hinckelmann, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-phospho myosin light chain 2 (Cell signaling, 1:1000), rabbit anti-cofilin (Abcam ...
• Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations

  Maria Victoria Hinckelmann, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-phospho myosin light chain 2 (Cell signaling, 1:1000), rabbit anti-cofilin (Abcam ...
• FGF9, a potent mitogen, is a new ligand for integrin αvβ3, and the FGF9 mutant defective in integrin binding acts as an antagonist

  Chih-Chieh Chang, et al., bioRxiv - Biochemistry 2023

  Quote: ... rabbit anti-p44/42 MAPK (ERK1/2) (Cell Signaling Technology, USA), anti-phospho-p44/42 MAPK (p-ERK1/2 ...
• FDA-Approved MEK1/2 Inhibitor, Trametinib, Protects Mice from Cisplatin and Noise-Induced Hearing Loss

  Richard D. Lutze, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-pERK1/2 (Thr202/Tyr204, 9101S, Cell Signaling Technologies, 1:1000) and anti-GAPDH (ab181602 ...
• Control of OPC proliferation and repopulation by the intellectual disability gene PAK1 under homeostatic and demyelinating conditions

  Yan Wang, et al., bioRxiv - Neuroscience 2024

  Quote: ... P-ERK1/2 (Thr202/Tyr204) (1:1000, #9101, Cell Signaling Technology), β-actin (1:1000 ...
• Ezrin defines TSC1 activation at endosomal compartments through EGFR-AKT signaling

  Giuliana Giamundo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-phospho-MAPKAPK-2 (Thr222) (1:1000, Cell Signaling 3316), rabbit anti-p38 MAPK (1:1000 ...
• Distinct Mechanisms of Type 3 Secretion System Recognition Control LTB₄ Synthesis in Neutrophils versus Macrophages

  Amanda Brady, et al., bioRxiv - Immunology 2024

  Quote: ... anti-p-p44/42 (ERK1/2) (Cell Signaling; Cat. No. 9101s), anti-p44/42 (Cell Signaling ...
• Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation

  Qin Ni, et al., bioRxiv - Biophysics 2024

  Quote: ... anti-p44/42 MAPK (ERK1/2; Cell Signaling; 4695; 1:1000). GAPDH was used as a loading control (Cell Signaling ...
• Notch1 mutation drives clonal expansion in normal esophageal epithelium but impairs tumor growth

  Emilie Abby, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-NOTCH2 targeting C terminus of the protein (Cell signaling, catalog no. 5732); alpha-TUBULIN (Cell signaling ...
• Cross-kingdom regulation of tRNAs/tRFs derived from Chinese yew

  Kai-Yue Cao, et al., bioRxiv - Cell Biology 2019

  Quote: ... and protein extraction was carried out using RIPA buffer (Cell Signaling Technology, U.S.A.) supplemented with protease and phosphatase inhibitor cocktails (Roche ...
• UFMylation regulates translational homeostasis and cell cycle progression

  Igor A. Gak, et al., bioRxiv - Cell Biology 2020

  Quote: ... Ribosomal protein L26/RPL26 (D8F6) rabbit mAb (Cell Signaling Technologies, 5400, 1:1000), Ribosomal protein L38/RPL38 rabbit polyclonal (Bethyl Laboratories ...
• SMAD2 Promotes Myogenin Expression and Terminal Myogenic Differentiation

  Émilie Lamarche, et al., bioRxiv - Cell Biology 2020

  Quote: ... Proteins were detected by the following antibodies: anti-Smad2 antibodies (Cell signaling, 5339S), anti-GKLF (KLF4 ...
• Myogenin is an Essential Regulator of Adult Myofibre Growth and Muscle Stem Cell Homeostasis

  Massimo Ganassi, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Primary antibodies used were: S6 ribosomal protein (pan) (1:1000; #2317; Cell Signaling), phospho-S6 ribosomal protein (Ser240/244 ...
• Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation

  Victoria E. B. Hipolito, et al., bioRxiv - Cell Biology 2019

  Quote: ... Ha-Tag and Tata-box binding protein (TBP; Cell Signaling Technologies, Danvers, MA), all at 1:1,000 ...
• The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

  Sheng Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1 mg of proteins were incubated with TCF7l2 antibody (#2569S, Cell Signaling Technology) or normal rabbit IgG (#2729 ...
• Gestational insulin resistance is mediated by the gut microbiome-indoleamine 2,3-dioxygenase axis

  Medha Priyadarshini, et al., bioRxiv - Physiology 2021

  Quote: ... Protein lysates from harvested tissues were prepared in RIPA lysis buffer (Cell Signaling), estimated using Bradford reagent (Bio-Rad) ...
• Global prediction of candidate R-loop binding and R-loop regulatory proteins

  Louis-Alexandre Fournier, et al., bioRxiv - Cell Biology 2021

  Quote: ... ChIP-Grade protein G magnetic beads (Cell Signaling, 9006S - 25 μL per IP) were pre-blocked in pre-blocking buffer (PBS/EDTA containing 0.5% BSA ...
• Substance P and adenosine signaling pathways regulate exosomal sorting of miR-21 in colonic epithelial cells

  Sameena Wani, et al., bioRxiv - Cell Biology 2022

  Quote: Total cellular and exosome proteins were isolated with RIPA buffer (Cell Signaling Technology) containing protease inhibitors (Cell Signaling Technology) ...
• G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

  Ewa Bielczyk-Maczynska, et al., bioRxiv - Physiology 2022

  Quote: ... Proteins were detected using primary antibodies against CREB (Cell Signaling, #9197, 1:1,000), p-CREB (Millipore Sigma ...
• Adaptive thermogenesis in mice requires adipocyte light-sensing via Opsin 3

  Gowri Nayak, et al., bioRxiv - Physiology 2019

  Quote: ... beta-tubulin (ab21057 at 1:2000) and lipolysis pathway proteins from Cell Signaling at 1:1000 -phospho 660-HSL (#4126) ...
• PLZF is a new substrate of CRBN with thalidomide and 5-hydroxythalidomide

  Satoshi Yamanaka, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... Biotinylated proteins were detected by anti-biotin (HRP-conjugated, Cell Signaling Technology, #7075). Anti-CRBN rabbit mAb (Cell Signaling Technology ...
• Sporadic ERK pulses drive non-genetic resistance in drug-adapted BRAF^V600E melanoma cells

  Luca Gerosa, et al., bioRxiv - Cancer Biology 2019

  Quote: ... proteins were detected using primary antibodies from Cell Signaling (EGFR, #4267, 1:1000) and Santa Cruz Biotechnology (Actin-HRP ...
• TRAF6-IRF5 kinetics, TRIF, and biophysical factors drive synergistic innate responses to particle-mediated MPLA-CpG co-presentation

  Pallab Pradhan, et al., bioRxiv - Immunology 2020

  Quote: ... Proteins of interest were detected with Anti-Rabbit IgG HRP (Cell signaling technologies) and visualized with Bio-Rad Clarity Max according to manufacturing protocol.
• Negative Regulation of Autophagy by UBA6-BIRC6–Mediated Ubiquitination of LC3

  Rui Jia, Juan S. Bonifacino, bioRxiv - Cell Biology 2019

  Quote: We used primary antibodies to the following proteins: LC3B (Cell Signaling Technology, 3868), UBA6 (Cell Signaling Technology ...
• Quantitative and temporal measurement of dynamic autophagy rates

  Nitin Sai Beesabathuni, Priya S. Shah, bioRxiv - Systems Biology 2021

  Quote: ... 1:1000 anti-S6 Ribosomal Protein (5G10) Rabbit mAb (Cell Signaling Technology, 2217), 1:1000 anti-LC3B (D11 ...
• Defining the RBPome of T helper cells to study higher order post-transcriptional gene regulation

  Kai P. Hoefig, et al., bioRxiv - Immunology 2020

  Quote: ... Proteins were visualized by staining with anti-rat (1:3000, 7077, Cell Signaling) or anti-mouse (1:3000 ...
• Creating a bottleneck: Robust LC3B lipidation analysis by adjusting autophagic flux with low concentrations of Bafilomycin A1

  Martina P. Liebl, et al., bioRxiv - Cell Biology 2021

  Quote: ... p-S6 ribosomal protein (S240/244) XP® rabbit mAB (5364S, Cell Signaling), S6 ribosomal protein mouse mAB (2317S ...
• A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway

  R. Samuel Herron, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit monoclonal anti-Phospho-S6 ribosomal protein (Ser240/244) (Cell Signaling Technology, 5364), rabbit polyclonal anti-CPSF6 (Bethyl Labs ...
• Inhibition of CHK2 dependent DNA damage response suppresses Zika virus infection through a STING dependent mechanism

  Huailiang Ma, et al., bioRxiv - Immunology 2022

  Quote: Antibodies against the following proteins were used: Phospho-CHK2 (Thr68) (Cell Signaling, #2197), Total CHK2 (Cell Signaling ...
• S100A1ct: a synthetic peptide derived from human S100A1 protein improves cardiac contractile performance and survival in pre-clinical heart failure models

  Dorothea Kehr, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... Badrilla: PLB pSer16 antibody Catalogue No.: A010-12) and total protein (Cell signaling: Troponin I Antibody #4002 and Phospholamban (D9W8M ...