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151 - 200 of 2267 citations for 5 Bromo 2 Tert Butyldimethylsilyl 4 Methylthiazole since 2020

• Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

  Brian Czaya, et al., bioRxiv - Cell Biology 2021

  Quote: ... ERK1/2 (4695, Cell Signaling), STAT3 (4904 ...
• Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

  Behnam Nabet, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (Cell Signaling, #4696), phospho-AKT S473 (Cell Signaling ...
• Peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

  Kanji Okumoto, et al., bioRxiv - Cell Biology 2020

  Quote: ... phospho-Erk1/2 (Cell Signaling), cytochrome P450 reductase (Santa Cruz Biotechnology ...
• LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer

  Donatella Delle Cave, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MMP-2 (4022S, Cell Signaling), Vimentin (3932 ...
• COMBINATION THERAPIES TARGETING ALK-ABERRANT NEUROBLASTOMA IN PRECLINICAL MODELS

  Elizabeth R. Tucker, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK1/2 (Cell Signaling #4695), pERK1/2 (Cell Signaling #9101) ...
• Hemodynamic stress activates inflammatory responses and cell death through spectrin-dependent modulation of Store Operated Calcium Entry

  Lance Hsieh, et al., bioRxiv - Cell Biology 2022

  Quote: ... ERK1/2 (4695, Cell Signaling), SPTAN1 (MAB1622 ...
• Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

  Florian J. Bock, et al., bioRxiv - Cell Biology 2020

  Quote: ... pERK1/2 (4370, Cell Signaling), CASPASE 3 (9662 ...
• Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

  Florian J. Bock, et al., bioRxiv - Cell Biology 2020

  Quote: ... BCL-2 (2762, Cell Signaling), ERK1/2 (4695 ...
• Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

  Florian J. Bock, et al., bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 (4695, Cell Signaling), FGFR1 (9740 ...
• Double-targeted knockdown of miR-21 and CXCR4 inhibits malignant glioma progression by suppression of the PI3K/AKT and Raf/MEK/ERK pathways

  Feijiao Liu, Bo Yang, bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (Cell Signaling Technology), and phospho-ERK1/2 (Cell Signaling Technology) ...
• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... SOX-2 (Cell Signaling; #4900S), βIII-tubulin (Abcam ...
• Cell autonomous requirement of imprinted XCI in extra-embryonic polar trophoblast cells

  Feng Wang, et al., bioRxiv - Developmental Biology 2022

  Quote: ... pErk1/2 (Cell Signaling #9102), Fgfr2 (Abcam 10648) ...
• Site-1 Protease inhibits mitochondrial metabolism by controlling the TGF-β target gene MSS51

  Muhammad G. Mousa, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Smad 2 (5339, Cell Signaling); Phospho-AKT (4060 ...
• COMBINATION THERAPIES TARGETING ALK-ABERRANT NEUROBLASTOMA IN PRECLINICAL MODELS

  Elizabeth R. Tucker, et al., bioRxiv - Cancer Biology 2022

  Quote: ... pERK1/2 (Cell Signaling #9101), AKT (Cell Signaling #9272) ...
• Resistance to PSEN1-selective γ-secretase inhibitors in T-cell acute lymphoblastic leukemia

  Charlien Vandersmissen, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PEN-2 (#8598, Cell signaling), nicastrin (9C3 ...
• Keratinocyte desmosomal cadherin Desmoglein 1 as a mediator and target of paracrine signaling in the melanoma niche

  Hope E. Burks, et al., bioRxiv - Cancer Biology 2022

  Quote: ... total ERK1/2 (Cell Signaling). The rabbit monoclonal antibody EP1576Y (ab52642 ...
• Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors

  Damien M. Rasmussen, et al., bioRxiv - Biophysics 2023

  Quote: ... and ERK1/2 (Cell Signaling). Membranes were washed and incubated for 1 h at RT with corresponding species-reactive secondary antibody and then imaged using an Odyssey CLx near-infrared imager (LI-COR Biosciences).
• The Role of Alpha-Synuclein in Synucleinopathy: Impact on Lipid Regulation at Mitochondria–ER Membranes

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2024

  Quote: ... ERLIN-2 (Cell Signaling; 2959S), protein kinase C (Sigma-Aldrich ...
• YAP dysregulation triggers hypertrophy by CCN2 secretion and TGFβ uptake in human pluripotent stem cell-derived cardiomyocytes

  Orlando Chirikian, et al., bioRxiv - Cell Biology 2024

  Quote: ... pMST1/2 (Cell Signaling 49332) and GAPDH (Proteintech-60004-1 ...
• Targeted KRAS^G12V degradation elicits efficient and durable lung adenocarcinoma regression in vivo

  Alberto Martín, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pERK1/2 (Cell Signaling, 9101), Phospho-S6 Ribosomal Protein Ser240/244 (Cell Signaling ...
• Prohibitin 2 is a Key Regulator of T Cell Proliferation and Effector Functions

  Johannes F. Vogt, et al., bioRxiv - Immunology 2024

  Quote: ... Erk1/2 (Cell Signaling #9102), p-Erk1/2 (Cell Signaling #9106) ...
• Abl kinases regulate FGF signaling independent of Crk phosphorylation to prevent Peters anomaly

  Hao Wu, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Erk1/2 (Cell Signaling, #4695), Abl (BD Pharmingen ...
• Endothelial Rho kinase controls blood vessel integrity and angiogenesis

  Martin Lange, et al., bioRxiv - Developmental Biology 2024

  Quote: ... pPAK1/2 (Cell Signaling, #2605S), PAK1/2/3 (Cell Signaling ...
• Endothelial Rho kinase controls blood vessel integrity and angiogenesis

  Martin Lange, et al., bioRxiv - Developmental Biology 2024

  Quote: ... pLIMK1/2 (Cell Signaling, # 3841S), LIMK1 (Cell Signaling ...
• Prenatal cadmium exposure alters proliferation in mouse CD4⁺ T cells via LncRNA Snhg7

  Jamie L. McCall, et al., bioRxiv - Immunology 2021

  Quote: ... GAPDH (D16H11; 51745, lot 4, Cell Signaling Technologies) 1:1000 ...
• Endothelial Caspase-9 Promotes Glial Changes, Inflammation, and Contrast Sensitivity Decline in Retinal Vascular Injury

  Crystal Colón Ortiz, et al., bioRxiv - Neuroscience 2022

  Quote: ... and AQP-4 (1:100 Cell Signaling 59678S) were prepared with blocking buffer and sections were incubated overnight at 4°C ...
• eIf2α-regulated translation modulates the early adhesion of mesenchymal-like cells

  Alexia Caillier, et al., bioRxiv - Cell Biology 2022

  Quote: ... α4 (8440; Cell Signaling Technology, Danvers, MA, USA), Hsp70 (C92F3A-5 ...
• PROTAC-mediated selective degradation of cytosolic soluble epoxide hydrolase enhances ER-stress reduction

  Yuxin Wang, et al., bioRxiv - Biochemistry 2022

  Quote: ... 4) XBP-1s (#12782, Cell Signaling, Danvers, MA); and 4 ...
• Contribution of 6mer seed toxicity to HIV-1 induced cytopathicity

  Aparajitha Vaidyanathan, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-Argonaute-4 (1:1000) (Cell Signaling #6913), anti-Dicer (1:1000 ...
• Dynamic control of gene expression by ISGF3 and IRF1 during IFNβ and IFNγ signaling

  Aarathy Ravi Sundar Jose Geetha, et al., bioRxiv - Immunology 2023

  Quote: ... and IRF1 (Cell signaling, Catalog # 8478, 4 µl). 50µl of magnetic beads per sample were added for 3 hours at 4°C while rotating ...
• TRIM5α restriction of HIV-1-N74D viruses in lymphocytes is caused by a loss of cyclophilin A protection

  Anastasia Selyutina, et al., bioRxiv - Microbiology 2020

  Quote: ... and activated with IL-2 (100 U/ml) (Human IL-2; Cell Signaling Technology, #8907SF) and phytohemagglutinin (1 µg/ml ...
• Preserving endothelial integrity in human saphenous veins during preparation for coronary bypass surgery

  Meghan W. Sedovy, et al., bioRxiv - Physiology 2023

  Quote: ... and nuclear factor erythroid 2-related factor 2 (NRF2, #12721, 1:25, Cell Signaling Technology). Antibody binding was identified by incubation with goat anti-rabbit or anti-mouse secondary antibodies (Thermo Fisher Scientific ...
• Resolving mechanisms of immune-mediated disease in primary CD4 T cells

  C Bourges, et al., bioRxiv - Genetics 2020

  Quote: ... 4°C) and immunoprecipitation was performed overnight at 4°C using an anti-NFkBp65 antibody (clone D14E12; Cell Signaling Technology 8242) or an isotype control (rabbit IgG monoclonal antibody ...
• SLX4IP-mediated telomere maintenance is essential for androgen receptor-independent castration-resistant prostate cancer

  Tawna L. Mangosh, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 1:5 000 p21 (Cell Signaling, 2947).
• Increased ACTL6A Occupancy Within mSWI/SNF Chromatin Remodelers Drives Human Squamous Cell Carcinoma

  Chiung-Ying Chang, et al., bioRxiv - Molecular Biology 2021

  Quote: ... YAP (Cell Signaling Technology, 14074S; 5 µl), Pan-TEAD (Cell Signaling Technology ...
• Targeting a proteolytic neo-epitope of CUB-domain containing protein 1 in RAS-driven cancer

  Shion A. Lim, et al., bioRxiv - Biochemistry 2021

  Quote: ... 5 µL CDCP1 antibody (D1W9N, Cell Signaling) was added into 200 µL cell lysate precleared by 20 µL Protein A magnetic beads (EMD Millipore ...
• Generation of a new Adar1p150^-/- mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis

  Zhen Liang, Carl R Walkley, Jacki E Heraud-Farlow, bioRxiv - Genetics 2022

  Quote: ... rabbit anti-MDA-5 (Cell Signaling, D74E4) and mouse anti-Actin (Sigma Aldrich ...
• Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops

  Iain Williamson, et al., bioRxiv - Molecular Biology 2023

  Quote: ... or 5 μg Rabbit IgG (Cell Signaling) respectively ...
• Intrinsic BMP inhibitor Gremlin regulates lung alveolar progenitor cell proliferation and differentiation

  Toyoshi Yanagihara, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Phospho-Smad1/5 (#9516S, Cell Signaling Technology), alpha-Tubulin (#2144S ...
• Control of neuronal excitation-inhibition balance by BMP-SMAD1 signaling

  Zeynep Okur, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-phosphoSMAD1/5/9 (Cell signaling #13820), mouse anti-BMPR2 (BD Pharmingen ...
• Integrative analysis reveals a conserved role for the amyloid precursor protein in proteostasis during aging

  Vanitha Nithianandam, et al., bioRxiv - Neuroscience 2023

  Quote: ... pSMAD1/5/9 (1:2000, Cell Signaling), GABARAP (1:2000 ...
• RNA structures within Venezuelan equine encephalitis virus E1 alter macrophage replication fitness and contribute to viral emergence

  Sarah E. Hickson, Jennifer L. Hyde, bioRxiv - Microbiology 2024

  Quote: ... MDA-5 Rabbit mAb (Cell signaling, D74E4), Fibrillarin/U3 RNP Rabbit pAb (ABclonal ...
• TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

  Luyang Xiong, et al., bioRxiv - Immunology 2023

  Quote: ... pSmad1/5/9 (Cell Signaling Technology, 13820S,), β-catenin (Cell signaling Technology ...
• Innate immune receptor C5aR1 regulates cancer cell fate and can be targeted to improve radiotherapy in tumours with immunosuppressive microenvironments

  Callum Beach, et al., bioRxiv - Cancer Biology 2023

  Quote: ... (5) FoxP3 (1:400, 126553; Cell Signaling)–Opal 650 ...
• Nuclear morphology predicts cell survival to cisplatin chemotherapy

  Chi-Ju Kim, et al., bioRxiv - Cancer Biology 2023

  Quote: ... docetaxel (5 nM; Cell Signaling Technology, #9886), or etoposide (25 μM ...
• Dynamic decoding of VEGF signaling and coordinated control of multiple phenotypes by the Src-TEM4-YAP pathway

  Sung Hoon Lee, Tae-Yun Kang, Andre Levchenko, bioRxiv - Systems Biology 2023

  Quote: ... 5 μM RPL30 Primer (Cell Signaling #7014) 2 μl or 100 μM target primers 0.4 μl and Taq DNA Polymerase 0.5 μl with the following PCR reaction program (Initial denaturation 95 °C for 5 minutes ...
• Listeria adhesion protein orchestrates caveolae-mediated apical junctional remodeling of epithelial barrier for L. monocytogenes translocation

  Rishi Drolia, et al., bioRxiv - Microbiology 2023

  Quote: ... and 5% normal goat serum (Cell Signaling) and immunostained with specific primary antibodies or a cocktail of primary antibodies (Table S2 ...
• ZO-1 regulates Hippo-independent YAP activity and cell proliferation via a GEF-H1- and TBK1-regulated mechanosensitive signalling network

  Alexis J. Haas, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit polyclonal (4911, Lot 5, Cell Signaling); TAZ ...
• Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain

  Gabriella O. Estevam, et al., bioRxiv - Molecular Biology 2024

  Quote: ... MET pY1234/5 (3077) (Cell Signaling Technologies).
• Skeletal muscle ribosome analysis: a comparison of common assay methods and utilization of a novel RiboAb antibody cocktail

  Joshua S. Godwin, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 5 µL rpl11 (Cell Signaling, cat #: 18163S), 5 µL rps3 (Cell Signaling ...