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1851 - 1900 of 3293 citations for IL 2 Mouse since 2019

• Jak2^V617F Reversible Activation Shows an Essential Requirement for Jak2^V617F in Myeloproliferative Neoplasms

  Andrew Dunbar, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and phospho-44/42 MAPK (Erk1/2) (Cell Signaling 4376, 1:100). Pictures were taken at 100X ...
• Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice

  Florence Njau, et al., bioRxiv - Cell Biology 2019

  Quote: ... Phospho-VEGFR-2 (Tyr1175) Sandwich ELISA Kit was from Cell Signaling Technology. Mouse albumin ELISA kit (Bethyl Lab ...
• Cortical ChAT⁺ neurons co-transmit acetylcholine and GABA in a target- and brain-region specific manner

  Adam J Granger, et al., bioRxiv - Neuroscience 2020

  Quote: ... Session 2 for PSD-95 (rabbit α-PSD95, 3450 Cell Signaling Tech.), Session 3 for VGAT (rabbit α-VGAT ...
• NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

  Carolina Marques, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (Cell Signaling Technology, #9102, 1:1000; Abcam #ab17942, 1:1000), p-MEK (S217/221 ...
• ATP allosterically stabilizes Integrin-linked kinase for efficient force generation

  Isabel M. Martin, et al., bioRxiv - Biophysics 2021

  Quote: ... phospho-Myosin Light Chain 2 (Thr18/Ser19) (Cell Signaling; 3674; 1:200), Paxillin (BD Transduction Laboratories ...
• MEK1/2 in Rhabdomyosarcoma

  Kenneth A. Crawford, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling Cat# 9101), ß-Actin (13E5 ...
• Oxidative Stress and Neuroinflammation in a Rat Model of Co-Morbid Obesity and Psychogenic Stress

  Jose M. Santiago Santana, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-rabbit SOD-2 (1:2000; catalog #13141S; Cell Signaling, Danvers, MA); anti-rabbit GFAP (1:5000 ...
• Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma

  Odessa R. Yabut, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-phospho-Erk1/2 (1:250 dilution; Cat. #: 4370, Cell Signaling); γH2AX (1:100 dilution ...
• Perineuronal net receptor PTPσ regulates retention of memories

  Angelina Lesnikova, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-p44/42 MAPK (Erk1/2) rabbit pAb (Cell Signaling Technology, #9102); anti-p70 S6 kinase rabbit pAb (Cell Signaling Technology ...
• Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

  Chirag Vasavda, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-phospho-ERK1/2 (T202/Y204) (Cell Signaling 4370, 1:2000), rabbit anti-ERK1/2 (Cell Signaling 4695 ...
• TOP-2 is differentially required for the proper maintenance of cohesin on meiotic chromosomes in C. elegans spermatogenesis and oogenesis

  Christine Rourke, Aimee Jaramillo-Lambert, bioRxiv - Genetics 2021

  Quote: ... rabbit anti-AIR-2 [(1:500) Figure 2B] (Cell Signaling Technology, 2914S), Histone H3 phospho-T3 (1:750 ...
• Venous activation of MEK/ERK drives development of arteriovenous malformation and blood flow anomalies with loss of Rasa1

  Jasper Greysson-Wong, et al., bioRxiv - Developmental Biology 2021

  Quote: Phospho-p44/42 MAPK (ERK1/2) (Thr2020/Tyr204) antibody (Cell Signaling, #9101) staining was performed as previously published (Randlett et al. ...
• A dynamic equilibrium between TTP and CPEB4 controls mRNA stability and inflammation resolution

  Clara Suñer, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Phospho-p44/42 (Erk1/2) (Thr202/Try204) (Cell Signaling Clon E10, 9106); SOCS1 (Abcam Ab9870) ...
• A BTB-Domain Transcription factor Recruits Chromatin Remodelers and a Histone Chaperone during the exit from Pluripotency

  Daniel Olivieri, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Separate membranes were probed with Erk1/2 antibody (Cell Signaling Technology, #9102) or Phospho-Erk1/2 antibody (Cell Signaling Technology ...
• Single Serine on TSC2 Exerts Biased Control over mTORC1 Activation by ERK1/2 but Not Akt

  Brittany L. Dunkerly-Eyring, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-p44/42 MAPK (ERK1/2) (Cell Signaling Technology, 1:1000). Total protein stain used was Revert Total Protein Stain (Licor) ...
• Metformin-mediated mitochondrial protection post-cardiac arrest improves EEG activity and confers neuroprotection and survival benefit

  Muhammad Shoaib, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Total AMPK β1/2 (1:1000; Cell Signaling Technology, Beverly, MA). Detection used anti-rabbit horseradish peroxidase–conjugated secondary antibody (1:2000 ...
• The RNA binding proteins ZFP36L1 and ZFP36L2 modulate transcriptional and post-transcriptional genome-wide effects of glucocorticoids

  Jennifer Rynne, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Precleared lysates were immunoprecipitated with BRF1/2 antibody (#2119, Cell Signaling Technology), Glucocorticoid Receptor antibody (#3660 ...
• Retinoid acid receptor β mechanically regulates the activity of pancreatic cancer cells

  Carlos Matellan, et al., bioRxiv - Bioengineering 2022

  Quote: ... or anti-MLC-2 antibodies (Cell Signaling Technology, 3672S, Rabbit, 1:100) and anti-PAN cytokeratin (Abcam ...
• Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer

  E. M. Poursani, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Phospho-p44/42 MAPK (pERK1/2)(T202/Y204) (D13.14.4E, Cell Signaling Technology), p44/42 MAPK (ERK1/2 ...
• Breast cancer mutations HER2^V777L and PIK3CA^H1047R activate the p21-CDK4/6 –Cyclin D1 axis driving tumorigenesis and drug resistance

  Xiaoqing Cheng, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell signaling technology, #9101). Secondary antibodies used include anti-rabbit IgG (H+L ...
• Cryptochromes and UBP12/13 deubiquitinases antagonistically regulate DNA damage response in Arabidopsis

  Yuzhao Hu, et al., bioRxiv - Plant Biology 2023

  Quote: ... anti-phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling Technology), anti-actin (MP Biomedicals ...
• Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice

  Ferrol I. Rome, et al., bioRxiv - Physiology 2022

  Quote: ... and 3-hydroxymethylglutaryl-CoA synthase 2 (HMGCS2; Cell Signaling Technology, 20940S; RRID:AB_2798853). All primary antibodies were used as a dilution of 1:1000 ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:1000; 9101; Cell Signaling Technology, Inc.); ERK1/2 (1:1000 ...
• Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression

  Giusy Pizzirusso, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:1000 anti-Synaptotagmin-2 polyclonal rabbit antibody (#60889, Cell Signaling Technology), 1:1000 anti-GABA-A Receptor beta 3 polyclonal rabbit antibody (#NB300-199 ...
• Mitochondrial Raf1 Regulates Glutamine Catabolism

  Ronald L. Shanderson, et al., bioRxiv - Cancer Biology 2024

  Quote: Primary antibodies used: p44/42 (ERK1/2)(L34F12)(4696S, Cell Signaling Technology), Phospho-p44/42 MAPK (ERK1/2)(Thr202/204)(9101S ...
• Mitochondrial Raf1 Regulates Glutamine Catabolism

  Ronald L. Shanderson, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK (ERK1/2)(Thr202/204)(9101S, Cell Signaling Technology),c-Raf (D4B3J ...
• An atlas of epithelial cell states and plasticity in lung adenocarcinoma

  Guangchun Han, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p44/42 MAPK (ERK1/2, rabbit, Cell Signaling Technology, 9102, 1:2000), or S6 (E.573.4 ...
• Bromodomain-containing Protein 4 Regulates Innate Inflammation in Airway Epithelial Cells via Modulation of Alternative Splicing

  Morgan Mann, et al., bioRxiv - Systems Biology 2023

  Quote: ... 2 μg α-RelA antibody (Cell Signaling, Danvers, MA, USA, Cat. # 8242) was added to each extract ...
• Culture conditions greatly impact the levels of vesicular and extravesicular Ago2 and RNA in extracellular vesicle preparations

  Lizandra Jimenez, et al., bioRxiv - Cancer Biology 2023

  Quote: Rabbit anti-Argonaute 2 (cat no. 2897) was purchased from Cell Signaling. Rat anti-Ago2 (cat no ...
• Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints

  Alexa C. Cannon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PAK 1/2/3 1:1000 (Cell Signaling Technology Cat# 2604, RRID:AB_2160225), Myc-Tag 1:1000 (Cell Signaling Technology Cat# 2276 ...
• Angpt1 binding to Tie1 regulates the signaling required for lymphatic vessel development in zebrafish

  Nanami Morooka, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-Phospho-p44/42 MAPK (Erk1/2) (1:500, Cell signaling), and mouse anti-RFP (1:500 ...
• Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2

  Pavlo Potalitsyn, et al., bioRxiv - Biochemistry 2023

  Quote: ... and IGF-2 Receptor/CI-M6PR (D3V8C) antibody (Cell Signaling, cat.no.14364). Anti-actin (20-33 ...
• Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron

  Da-Yuan Chen, et al., bioRxiv - Microbiology 2023

  Quote: ... An anti-SARS-CoV-2 S antibody (Cell Signaling technologies: clone E5S3V) that showed equivalent immunoreactivity against WT and Omicron spike was used to identify virus-infected cells ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Phospho-p44/42 (ERK1/2) (1:1000, 197G2, 4377T, Cell Signaling), anti-p44/42 (ERK1/2 ...
• Macrophage migration is differentially regulated by distinct ECM components

  Matthew W. Stinson, et al., bioRxiv - Cell Biology 2023

  Quote: ... Phospho-Myosin Light Chain 2 antibody (for immunofluorescence) (Polyclonal, Cell Signaling, #3674); Goat anti-Rabbit IgG Rhodamine Red-X (RRX ...
• Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer

  Amir Hosseini, et al., bioRxiv - Cell Biology 2023

  Quote: ... F(ab’)2 Fragment (Alexa Fluor 647 Conjugate (Cell Signaling Technology, 4410) for 1 hour at room temperature ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p-p44/42 MAPK (pERK1/2) (Cell Signaling Technology, 9101S, 1:1,000) and β-actin (Cell Signaling Technology ...
• Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular cells

  Yihong Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... phosphor-p42/44 MAPK (p-ERK1/2, Cell Signaling Technology, Danvers, MA) and GAPDH (Cell Signaling Technology ...
• Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

  Zhuxuan Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (#4370, Cell Signaling Technology, 1:1000), ERK (#9102S ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:1000, Cell Signaling Technology, Cat# 9106), ERK1/2 (1:1000 ...
• Subfamily C7 Raf-like kinases MRK1, RAF26, and RAF39 regulate immune homeostasis and stomatal opening in Arabidopsis thaliana

  Márcia Gonçalves Dias, et al., bioRxiv - Plant Biology 2023

  Quote: ... 1:2,000 rabbit anti-p44/42 MAPK (Erk1/2) (Cell Signaling 9102S); 1:10,000 goat anti-rabbit-IgG (Sigma A0545) ...
• Diet-induced obesity results in endothelial cell desensitization to VEGF-A and permanent islet vascular dysfunction

  Yan Xiong, et al., bioRxiv - Physiology 2023

  Quote: ... Erk1/2 antibody (rabbit, 1:2000; all from Cell Signaling Technology, USA), and α-tubulin antibody (mouse,1:1000 ...
• Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia

  Ling Zhou, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... ERK1/2 (4696S) were obtained from Cell Signaling Technology (Boston, MA, USA), against NFE2 (11089-1-AP) ...
• Drug-Induced p53 Activation Promotes Acinar Cell Identity and Prevents Pancreatic Cancer Initiation

  Jennifer J Twardowski, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit monoclonal anti-p-ERK1/2 (Cell Signaling Technology 4370S, 1:100), rabbit polyclonal anti-p53 (Invitrogen PA5-88098 ...
• Urban wastewater contains a functional human antibody repertoire of mucosal origin

  Sean Stephenson, et al., bioRxiv - Immunology 2024

  Quote: ... SARS-CoV-2 Spike Protein Serological IgG ELISA Kit (Cell Signaling, #20154C), and SARS-CoV-2 Spike Protein Serological IgA ELISA Kit (Cell Signaling ...
• Viral Insulin/IGF-like Peptides Selectively Activate Host Insulin/IGF Signaling pathways during Grouper Iridovirus Infection

  Aurelien Chuard, et al., bioRxiv - Microbiology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody (Cell Signaling #9101); p44/42 MAPK (Erk1/2 ...
• Targeting oncogenic K-Ras mutants with a small-molecule degrader through Nedd4-1

  Taoling Zeng, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and anti-MEK1/2 (9122) antibodies were purchased from Cell Signaling Technology; rabbit anti-K-Ras (BS6231 ...
• Distinct and interchangeable growing patterns in colorectal cancer stem-like cells are regulated by Musashi-1

  Roberto Coppo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Secondary anti-rabbit (#7074) and -mouse (#7076) antibodies were obtained from Cell Signaling Technology. All antibodies were used at the producer’s suggested concentrations.
• Inactivation of the Hippo Tumor Suppressor Pathway Promotes Melanoma

  Marc A. Vittoria, et al., bioRxiv - Cancer Biology 2021

  Quote: ... incubated with anti-rabbit or mouse SignalStain Boost IHC detection reagent (Cell Signaling Technology) for 30 min and then developed with SignalStain DAB substrate kit (Cell Signaling Technology ...
• UFMylation regulates translational homeostasis and cell cycle progression

  Igor A. Gak, et al., bioRxiv - Cell Biology 2020

  Quote: ... Ribosomal protein S3 (D50G7) XP® mouse mAb (Cell Signaling Technologies, 9538, 1:1000), Ribosomal protein L23/RPL23 rabbit polyclonal (Bethyl Laboratories ...