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1651 - 1700 of 10000+ citations for 1 Piperidin 4 yl azetidine 3 carboxylic acid since 2020

• The DNA Damage response and cell competition are p53- and Xrp1-dependent processes that suppress hyperplastic aneuploidy

  Chaitali Khan, Nicholas E. Baker, bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-cleaved Dcp-1 (Cell Signaling 9578, 1:200), mouse anti-γH2Av (DSHB UNC93-5.2.1 ...
• Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival

  K. Pfeifer, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rb-anti-Dcp-1 (1:50; Cell Signaling Technology #9578), Developmental Studies Hybridoma Bank ...
• β-Catenin-NFκB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction

  Shikai Hu, et al., bioRxiv - Pathology 2021

  Quote: ... Histone H3 (Cell Signaling, 9715, 1:1000 in 1% milk). Membranes were washed in Blotto buffer and incubated with the appropriate HRP-conjugated secondary antibody for 75 minutes at room temperature ...
• Overexposure to apoptosis via disrupted glial specification perturbs Drosophila macrophage function and reveals roles of the CNS during injury

  Emma Louise Armitage, et al., bioRxiv - Immunology 2020

  Quote: ... Rabbit anti-cDCP-1 (9578S 1:1000; Cell Signaling Technologies), mouse anti-Repo (concentrate of clone 8D12 used at 1:1000 ...
• KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy

  Katrin Linda, et al., bioRxiv - Neuroscience 2020

  Quote: ... p-ULK1 (1:1000; Ser757) (1:1000; Cell Signaling 14202), and LAMP1 (1:200 ...
• Targeting of MCL-1 in breast cancer associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties

  TL Bonneaud, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Mcl-1 (1:800, Cell Signaling Technology, Danvers, MA, USA); Vimentin (1:100 ...
• Ankyrin-B is lipid-modified by S-palmitoylation to promote dendritic membrane scaffolding of voltage-gated sodium channel Nav1.2 in neurons

  Julie P. Gupta, Paul M. Jenkins, bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Flotillin-1 antibody (Cell Signaling Technologies, 1:1000), rabbit/mouse anti-HA antibody (Cell Signaling Technologies ...
• Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity

  Claudia Feriotti, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-caspase-1 (anti-rabbit, 1:1000; #24232, Cell Signaling), anti-AIM2 (anti-rabbit ...
• Targeting the Src pathway enhances the efficacy of selective FGFR inhibitors in cancers with FGFR3 alterations

  Nadia Carvalho Lima, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Anti-rabbit HRP (7074) 1:2000-1:10,000 (Cell Signaling) and anti-mouse HRP (G32-62G-1000 ...
• Neuronal octopamine signaling regulates mating-induced germline stem cell proliferation in female Drosophila melanogaster

  Yuto Yoshinari, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit cleaved Dcp-1 (Cell Signaling Technology #9578; 1:100), rat anti-Vasa (DSHB ...
• Lineage reversion drives WNT independence in intestinal cancer

  Teng Han, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-ETS-1 (1:1000, Cell Signaling Technologies, #14069), rabbit anti-GAPDH (1:1000 ...
• V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis

  Miriam Formica, et al., bioRxiv - Genetics 2020

  Quote: ... rabbit anti-ERK 1/2 1:1000 (4695, Cell Signaling). Western blots protein levels were analyzed using Image Lab (Biorad).
• Selective localization of Mfn2 near PINK1 enable its preferential ubiquitination by Parkin on mitochondria

  Marta Vranas, et al., bioRxiv - Biochemistry 2021

  Quote: ... rabbit anti-mitofusin 1 (1:100, mAb 13196S, Cell Signaling), rabbit anti-Miro1 (1:50 ...
• KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance

  Anastasia-Maria Zavitsanou, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-PD-1 (D4W2J, Cell Signaling Technology, 1/200, Opal520), anti-Foxp3 (236A/E7 ...
• Condensation of the Drosophila Nerve Cord is Oscillatory and depends on Coordinated Mechanical Interactions

  Katerina Karkali, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-Dcp-1 (Asp216) (1:100, Cell Signaling #9578), rabbit anti-GFP tag polyclonal (1:600 ...
• Direct control of translational elongation by TAOK2β highlights altered protein synthesis as a fundamental underlying component of autism

  Melad Henis, et al., bioRxiv - Neuroscience 2022

  Quote: ... (Cell Signaling Technology; 2278, WB 1:1,000, ICC 1:300); rabbit anti-IgG (Millipore ...
• RhoA activation promotes glucose uptake to elevate proliferation in MAPK inhibitor resistant melanoma cells

  Vasanth Siruvallur Murali, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Insulin receptor substrate 1 1:1000(Cell Signaling Technology, 2383L), Ser636/639 Phospho-Insulin receptor substrate 1 (Cell Signaling Technology ...
• Caspase cleavage of Influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production

  Carmen Figueras-Novoa, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit polyclonal PARP-1 (Cell Signaling, 9542, WB 1:1000).
• Protective role of Pten downregulation in Huntington’s Disease models

  Nisha, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Dcp-1 (1:100; 9578; Cell Signaling Technology, USA), anti-Dlg1 (1:100 ...
• Activation of intestinal immunity by pathogen effector-triggered aggregation of lysosomal TIR-1/SARM1

  Samantha Y. Tse-Kang, et al., bioRxiv - Immunology 2024

  Quote: ... 1:1000 phospho p38 PMK-1 (Cell Signaling Technology, #9211), 1:1000 total PMK-1,45 1:2000 mouse monoclonal anti-alpha-Tubulin (Sigma ...
• Lysosomal integrity suppresses TIR-1/SARM1 aggregation to restrain toxic propagation of p38 innate immunity

  Samantha Y. Tse-Kang, Read Pukkila-Worley, bioRxiv - Immunology 2024

  Quote: ... 1:1000 phospho p38 PMK-1 (Cell Signaling Technology, #9211), 1:1000 total PMK-1,23 1:2000 mouse monoclonal anti-alpha-Tubulin (Sigma ...
• The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle atrophy

  Yurika Ito, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-TRA-1-81 (diluted 1:200, Cell Signaling Technology), anti-NANOG (diluted 1:200 ...
• N-glycosylation engineering in chimeric antigen receptor T cells enhances anti-tumor activity

  Elien De Bousser, et al., bioRxiv - Immunology 2023

  Quote: ... monoclonal rabbit anti-galectin-1 (1:200, Cell Signaling, 13888S) or monoclonal rabbit anti-galectin-3 (1:200 ...
• IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A

  Magdalena Gebert, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-XBP-1 (S) (1:1000, D2C1F, Cell Signaling). After the washing steps ...
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-human caspase-1 (1:1,000, #3866, Cell Signaling Technology), anti-caspase-1 (1:1,000 ...
• In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

  Jerry J. Fan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-Caveolin-1 (Cell Signaling Technology #3267, 1:400), rabbit anti-Clathrin Heavy Chain (Cell Signaling Technology #4796 ...
• In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

  Jerry J. Fan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-Caveolin-1 (Cell Signaling Technology #3267, 1:200), rabbit anti-DCX (abcam #ab18723 ...
• Regenerative growth is constrained by brain tumor to ensure proper patterning in Drosophila

  Syeda Nayab Fatima Abidi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and anti-cleaved Dcp-1 (1:250)(Cell Signaling #9578). The Developmental Studies Hybridoma Bank (DSHB ...
• Stress-induced Rab11a-exosomes induce AREG-mediated cetuximab resistance in colorectal cancer

  John D. Mason, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-Caveolin-1 (Cell Signaling Technology #3238, 1:500), goat anti-AREG (R&D Systems #AF262 ...
• Cell-cycle dependent inhibition of BRCA1 signaling by the lysine methyltransferase SET8

  Yannick Perez, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-53PB1 (1:500, Cell Signaling and 1:1000, Millipore), anti-RNF168 (1:100 ...
• Mechanical activation of VE-cadherin stimulates AMPK to increase endothelial cell metabolism and vasodilation

  Nicholas M. Cronin, et al., bioRxiv - Cell Biology 2024

  Quote: ... and monoclonal Pecam-1 at 1:500 (Cell Signaling; 89C2). Cells were washed with PBS and the following secondary antibodies were diluted 1:1000 in 10% BSA anti-rabbit alexa-488 and/or anti-mouse alexa-647 and allowed to incubate for 2 hours at room temperature ...
• Upregulating ANKHD1 in PS19 mice reduces Tau phosphorylation and mitigates Tau-toxicity-induced cognitive deficits

  Xiaolin Tian, et al., bioRxiv - Neuroscience 2024

  Quote: ... and rabbit anti-Iba-1 (1:1,000, Cell Signaling #17198). For secondary antibodies ...
• Identification of novel myokines and putative protein targets that mediate functional adaptations in response to chronic contractile activity induced skeletal muscle-extracellular vesicle treatment

  Patience O. Obi, et al., bioRxiv - Cell Biology 2024

  Quote: ... and rabbit anti-Profilin-1 (3237, Cell Signaling, 1:200). Subsequently ...
• NUAK1 regulates contraction in vascular smooth muscle cells derived from abdominal aortic aneurysm patients

  Karlijn B. Rombouts, et al., bioRxiv - Cell Biology 2024

  Quote: ... NUAK family kinase 1 (1:1000, #4458, Cell Signaling technology), phosphorylated Myosin light chain (Ser19 ...
• Integrin β3 Targeting Biomaterial Preferentially Promotes Secretion of bFGF and Proliferation of iPSC-Derived Vascular Smooth Muscle Cells

  Biraja C. Dash, et al., bioRxiv - Bioengineering 2021

  Quote: ... The plates were then washed 3 times with PBST before adding 100 μl of TMB substrate solution (Cell Signaling Technology, USA, Catalog: 7004S) to the plates after aspirating out the PBST and was incubated for 25 minutes at room temperature on a plate shaker ...
• Mitochondrial diabetes in mice expressing a dominant-negative allele of nuclear respiratory factor-1 (Nrf1) in pancreatic β-cells

  Fionnuala Morrish, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Apoptotic cells were identified in paraffin-embedded sections by immuno-staining with activated cleaved caspase 3 antibody (Cell Signaling Technologies, Inc., Danvers, MA). Immunohistochemistry was performed using guinea pig antiinsulin primary antibody (Fitzgerald Labs ...
• Development of adaptive anoikis resistance promotes metastasis that can be overcome by CDK8/19 Mediator kinase inhibition

  Mehri Monavarian, et al., bioRxiv - Cancer Biology 2023

  Quote: ... OV90 and CAOV3 cells were cultured in a glass bottom 96 well plate as described and stained with Cleaved caspase 3 (CC3) antibody (Cell signaling technology: 9661T) at 1:100 dilution after 12 hours incubation with T cells for CAOV3 and 48 hours incubation for OV90 cells ...
• Protein Structure Inspired Drug Discovery

  Fangfang Qiao, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and Western blot performed on resultant protein as described by us.[85] Samples were probed using antibody against cleaved caspase 3 (Cell Signaling Technology, #9664) and β-actin (Santa Cruz ...
• Semaglutide Improves Myocardial Perfusion and Performance in a Large Animal Model of Coronary Artery Disease

  Christopher R. Stone, et al., bioRxiv - Molecular Biology 2024

  Quote: ... All membranes were additionally normalized for variation in loading by incubation with vinculin or glyceraldehyde-3-phosphate dehydrogenase (GAPDH, both Cell Signaling, Danvers, MA). After overnight incubation ...
• The nuclear receptor RORα preserves cardiomyocyte mitochondrial function by regulating mitophagy through caveolin-3

  JY Beak, et al., bioRxiv - Molecular Biology 2020

  Quote: ... VDAC1 (#4661, 1:000), HA (#3724, 1:1000), LC3B (#83506, 1:500), and Hsp60 (#12165, 1:1000) were from Cell Signaling Technology (Danvers, MA, USA). GAPDH (MAB374 clone 6C5 ...
• TRIM46 is not required for axon specification or axon initial segment formation in vivo

  Allison J. Melton, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:1000) and TRIM46 (#1 in text: Abcam Cat# ab307967, RRID:AB_3096363, 1:200-1:1000, #2 in text: Cell Signaling Technology Cat# 92574, RRID:AB_3096364, 1:200), rabbit polyclonal antibodies against βIV-spectrin (M.N ...
• OTUD1 deubiquitylase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways

  Daisuke Oikawa, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1:1,000), Lamin A/C (#4777, 1:1,000), and GST (#2622, 1:1,000) were obtained from Cell Signaling. HOIL-1L (sc-393754 ...
• Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila

  Jyoti Singh, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-Vg (1:100), rabbit anti DCP-1 (1:100, 9578) was procured from Cell Signaling Technology, rabbit anti-HA (1:100 ...
• Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples

  Feng Cai, et al., bioRxiv - Biochemistry 2022

  Quote: ... 0.1% Tween-20)) and then incubated with primary antibodies (PC: Proteintech, 16588-1-AP, 1:1000 dilution, or β-actin: Cell Signaling, 8457S, 1:1000 dilution) in TBST supplemented with 5% BSA at 4°C overnight ...
• Methionine Restriction Reduces Lung Cancer Progression and Increases Chemotherapy Response

  Kassandra J. Naughton, et al., bioRxiv - Cancer Biology 2024

  Quote: ... membranes were cut for different antibodies depending on protein size and placed into the appropriate antibody solution made in TBST (CBS 1:1000 Cell Signaling Technologies CAT#: 14782S, EZH2 1:250-1:500 Cell Signaling Technologies CAT#: 5246S, LKB1 1:1000 Cell Signaling Technologies CAT# ...
• Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimer’s mouse model

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... phospho-Beclin-1 (Ser15) (1:1000, Cell Signaling Technology, cat. # 84966), PGC1α (1∶1000 ...
• Retromer Combinatorials for Gene-Therapy Across a Spectrum of Neurological Diseases

  Yasir H. Qureshi, et al., bioRxiv - Neuroscience 2020

  Quote: ... Sorl1 (611861, BD-biosciences, 1:2k & 79322, Cell Signaling, 1:500), and β-actin (ab6276 ...
• The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

  Sheng Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... P-Smad 1/5 (1:200, RRID:AB_491015, #9516, Cell Signaling Technology), CC1 (1:100 ...
• A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1

  Lisa Donker, et al., bioRxiv - Cell Biology 2021

  Quote: ... Wee1 (D10D2, Cell signaling; 13084, 1:500 IF, 1:1000 WB), α-actinin (BM-75.2 ...
• Human skeletal muscle CD90⁺ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

  Jean Farup, et al., bioRxiv - Cell Biology 2020

  Quote: ... Perilipin-1 (rabbit, 1:200, Cat. no. 9349, Cell Signaling Technologies), CD34 (rabbit ...