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101 - 150 of 1797 citations for Locostatin CAS 90719 30 5 100% since 2020

• Matriptase generates a tissue damage response via promoting Gq signalling, leading to RSK and DUOX activation

  MA Jiajia, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1:100 (#4370, Cell Signaling Technology), Rabbit anti-p44/42 MAPK (Erk1/2) ...
• Neuronal hemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein

  Santulli Chiara, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-MYC 1:100 (Cell Signaling) and anti-Hemoglobin 1:1000 (MP Biomedicals) ...
• Dynamic control of metabolic zonation and liver repair by endothelial cell Wnt2 and Wnt9b revealed by single cell spatial transcriptomics using Molecular Cartography

  Shikai Hu, et al., bioRxiv - Pathology 2022

  Quote: ... GFP (Cell signaling, 2956, 1:100), Cyclin D1 (abcam ...
• Dynamic control of metabolic zonation and liver repair by endothelial cell Wnt2 and Wnt9b revealed by single cell spatial transcriptomics using Molecular Cartography

  Shikai Hu, et al., bioRxiv - Pathology 2022

  Quote: ... GFP (Cell signaling, 2956, 1:100), in antibody diluent and incubated at 4°C overnight ...
• A Novel Mouse Model that Recapitulates the Heterogeneity of Human Triple Negative Breast Cancer

  Zinab O. Doha, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD4 (Cell Signaling #25229, 1:100); MHCII (eBioscience #eB14-5321 ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... YFP (Cell Signaling 2956, 1:100), Slug (Cell Signaling 9585 ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... Slug (Cell Signaling 9585, 1:100), acetylated-tubulin (Cell Signaling 5335 ...
• Matriptase generates a tissue damage response via promoting Gq signalling, leading to RSK and DUOX activation

  MA Jiajia, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1:100 (#9102, Cell Signaling Technology), Rabbit anti-p90RSK (Phospho-Thr348) ...
• Intermediate Progenitor cells provide a transition between hematopoietic progenitors and their differentiated descendants

  Carrie M. Spratford, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbitαdpERK (1:100, Cell Signaling #4370), and αL1 (1:10 ...
• Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice

  Chunxing Yang, et al., bioRxiv - Genetics 2021

  Quote: ... NF-L (Cell Signaling, #2837,1:100), CNPase (Cell Signaling ...
• Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice

  Chunxing Yang, et al., bioRxiv - Genetics 2021

  Quote: ... CNPase (Cell Signaling, #5664s,1:100), MBP(Abcam,ab62631,1:100) ...
• LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium

  Rosalie T. Zwiggelaar, et al., bioRxiv - Developmental Biology 2020

  Quote: ... H3K4me1 (1:100, Cell Signaling 9723) and H3K4me2 (1:1500 ...
• Regulation of Blos1 by IRE1 prevents the accumulation of Huntingtin protein aggregates

  Donghwi Bae, et al., bioRxiv - Cell Biology 2022

  Quote: ... RAB7 (Cell Signaling 9367, 1:100), or FLAG (Sigma F3165 ...
• p16^High senescence restricts totipotent potential during somatic cell reprogramming

  Bogdan B. Grigorash, et al., bioRxiv - Cell Biology 2022

  Quote: ... Nanog (Cell Signaling #8822, 1:100), Desmin (Abcam #15200 ...
• A Conserved Mechanism of Cardiac Hypertrophy Regression through FoxO1

  Thomas G. Martin, et al., bioRxiv - Physiology 2024

  Quote: ... LC3B (Cell Signaling, 2755, 1:100), Puromycin (Sigma ...
• DMSO derives Trophectoderm and Clonal Blastoid from Single Human Pluripotent Stem Cell

  Samhan Alsolami, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 100 nM of Gö6976 (Cell Signaling), 10 μM of PKCý pseudosubstrate inhibitor (Life Technologies) ...
• TRPML1 activation ameliorates lysosomal phenotypes in CLN3 deficient retinal pigment epithelial cells

  D. Wünkhaus, et al., bioRxiv - Cell Biology 2023

  Quote: ... TFEB (Cell Signaling, 4240, 1:100), goat anti-mouse IgG (H+L) ...
• TGFB1 Induces Fetal Reprogramming and Enhances Intestinal Regeneration

  Lei Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... SOX9 (Cell Signaling 82630, 1:100) and DAPI (Biotium 40043 ...
• Oncogenic Kras^G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8⁺ T cells dependent manner

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD19 (Cell Signaling 3574s; 1:100), CD8 (Cell Signaling 85336S ...
• Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury

  Mary E. Mohr, et al., bioRxiv - Cell Biology 2023

  Quote: ... pMLKL (1:100, Cell Signaling, D6E3G), PTGS2 (1:100 ...
• Early embryogenesis in CHDFIDD mouse model reveals facial clefts and altered craniofacial neurogenesis

  M Hampl, et al., bioRxiv - Developmental Biology 2023

  Quote: ... SOX2 (1:100, 2748s, Cell Signaling), SOX9 (1:100 ...
• PRMT1 Inhibition Selectively Targets BNC1-Dependent Proliferation, but not Migration in Squamous Cell Carcinoma

  Rafik Boudra, et al., bioRxiv - Cancer Biology 2023

  Quote: ... IRF6 (Cell Signaling, 6948, 1:100), Ki67 (NCL-Ki67p ...
• Early and late chaperone intervention therapy boosts XBP1s and ADAM10, restores proteostasis, and rescues learning in Alzheimer’s Disease mice

  Jennifer M. Hafycz, et al., bioRxiv - Neuroscience 2023

  Quote: ... peIF2α (1:100, Cell Signaling 3597S); BiP/anti-KDEL (1:1000 ...
• Non-homologous end joining shapes the genomic rearrangement landscape of chromothripsis from mitotic errors

  Qing Hu, et al., bioRxiv - Cell Biology 2023

  Quote: ... 100 nM calyculin A (Cell Signaling) were added to directly to the cell culture medium and incubated for one hour at 37°C ...
• Microglia mediate the early-life programming of adult glucose control

  M Valdearcos, et al., bioRxiv - Physiology 2024

  Quote: ... glucagon (1:100, rabbit, Cell Signaling) and somastotatin (1:500 ...
• ER Ca²⁺-levels control neuromodulator secretion by regulating L-type Ca²⁺-channel activity

  Rein I. Hoogstraaten, et al., bioRxiv - Neuroscience 2024

  Quote: ... polyclonal STIM1 (1:100, Cell Signaling), polyclonal STIM2 (1:100 ...
• ER Ca²⁺-levels control neuromodulator secretion by regulating L-type Ca²⁺-channel activity

  Rein I. Hoogstraaten, et al., bioRxiv - Neuroscience 2024

  Quote: ... polyclonal STIM2 (1:100, Cell Signaling), monoclonal HA-tag (1:800 ...
• Glutamatergic regulation of miRNA-containing exosome precursor trafficking and secretion from cortical neurons

  Marcela Bertolio, et al., bioRxiv - Neuroscience 2024

  Quote: ... EEA1 (1:100, Cell Signaling #3288), Golga5 (1:100 ...
• Glutamatergic regulation of miRNA-containing exosome precursor trafficking and secretion from cortical neurons

  Marcela Bertolio, et al., bioRxiv - Neuroscience 2024

  Quote: ... Golga5 (1:100, Cell Signaling #A15768), mouse CD63 (1:50 ...
• ACSS2 regulates ferroptosis in an E2F1-dependent manner in breast cancer brain metastatic cells

  Emily M. Esquea, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ACSS2 (Cell Signaling Technology 1:100), GFAP (Life Technologies 2.2B10 1:100 ...
• Latrophilins are essential for endothelial junctional fluid shear stress mechanotransduction

  Keiichiro Tanaka, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Anti-Phospho-Smad1/5 (Cell signaling) (13820) ...
• Unbiased and UMI-informed sequencing of cell-free miRNAs at single-nucleotide resolution

  M.A.J. van Eijndhoven, et al., bioRxiv - Genomics 2021

  Quote: ... Exportin 5 (#12565S; Cell Signaling Technology), Dicer (#5362 ...
• Human GBP1 promotes pathogen vacuole rupture and inflammasome activation during Legionella pneumophila infection

  Antonia R. Bass, Sunny Shin, bioRxiv - Microbiology 2020

  Quote: ... caspase-5 (D3G4W; 46680S; Cell Signaling), Gasdermin-D (126-138 ...
• Optogenetic Instruction of Cell Fate by Temporal Patterning of Mechanobiological Signals

  Rocío G. Sampayo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... pSMAD1/5 (1:400, Cell Signaling), mCherry (1:1000 ...
• An isogenic human iPSC model unravels neurodevelopmental abnormalities in SMA

  Tobias Grass, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 5% NGS (Cell Signaling, 5424S), immunostained with the indicated primary antibodies for 2h at RT and secondary antibodies for 1h at RT ...
• Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid

  Min Pan, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pSMAD1/5/9 (Cell Signaling, # 13820S), ACVR1 (Abcam ...
• PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification

  José Antonio Valer, et al., bioRxiv - Molecular Biology 2024

  Quote: ... p-SMAD1/5 (Cell Signaling, 9516), and vinculin (Sigma ...
• Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development

  Divyesh Joshi, et al., bioRxiv - Cell Biology 2024

  Quote: ... pSmad1/5/8 (Cell Signaling Technology), GAPDH (Sigma Chemical Co. ...
• Secreted exosomes induce filopodia formation

  Caitlin McAtee, et al., bioRxiv - Cell Biology 2024

  Quote: ... pSmad1/5/9 (Cell Signaling #13820) and Smad1 (Cell Signaling #6944 ...
• Inactivation of the Hippo Tumor Suppressor Pathway Promotes Melanoma

  Marc A. Vittoria, et al., bioRxiv - Cancer Biology 2021

  Quote: ... for 30 min and then developed with SignalStain DAB substrate kit (Cell Signaling Technology) according to manufacturer’s instructions ...
• Excess ribosomal protein production unbalances translation in Fragile X Syndrome

  Sang S. Seo, et al., bioRxiv - Neuroscience 2022

  Quote: ... Membranes were then incubated with HRP-conjugated secondary antibodies for 30 minutes (Cell Signaling), developed with Clarity ECL (BioRad) ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (4695, 1:30, Cell Signaling Technology), anti-Hrs (sc-271455 ...
• Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer

  Mindy K Graham, et al., bioRxiv - Cancer Biology 2023

  Quote: ... F4/80 (Cell Signaling, Ca. No 70076) diluted 1:200 with 36 minutes of incubation ...
• Capitella teleta gets left out: Possible evolutionary shift causes loss of left tissues rather than increased neural tissue from dominant-negative BMPR1

  Nicole B. Webster, Néva P. Meyer, bioRxiv - Developmental Biology 2023

  Quote: ... and 1:400 rabbit anti-phosphorylated-SMAD1/5/8 (pSMAD1/5/8; clone 41D10, Cell Signaling Technologies). Secondary antibodies used were as follows ...
• The conserved ER-transmembrane protein TMEM39 coordinates with COPII to promote collagen secretion and prevent ER stress

  Zhe Zhang, et al., bioRxiv - Cell Biology 2020

  Quote: ... cells were lysed on ice for 30 min in cell lysis buffer (Cell signaling, 9803) with protease inhibitor cocktail (SIGMA 11836153001) ...
• Integrating transcription factor abundance with chromatin accessibility in human erythroid lineage commitment

  Reema Baskar, et al., bioRxiv - Genomics 2021

  Quote: ... for 30 mins at room temperature and FITC anti-rabbit secondary (Cell Signaling Technologies #4412S) for 30 mins ...
• Vcam1+ Fibro-adipogenic Progenitors Mark Fatty Infiltration in Chronic Limb Threatening Ischemia

  Qunsheng Dai, et al., bioRxiv - Genomics 2024

  Quote: ... was applied for 30 minutes at RT followed by primary antibodies [perilipin (Cell signaling, 9349S), PPARg (Cell signaling ...
• CD40 ligation-induced ERK activation promotes autophagy which leads to enhanced radiosensitivity in cervical carcinoma cells

  Baocai Liu, et al., bioRxiv - Cell Biology 2024

  Quote: ... for 24 h or pretreated for 30 min with 10 µM U0126 (Cell Signaling Technology) before being stimulated with CD40L ...
• Aberrant epigenetic and transcriptional events associated with breast cancer risk

  Natascia Marino, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 0.1%TritonX-100) steps cells were incubated with primary either rabbit anti-vimentin (Cell Signaling, D21H3, 1:100) or mouse anti-E-cadherin (Cell Signaling ...
• Notch and LIM-homeodomain protein Arrowhead regulate each other in a feedback mechanism to play a role in wing and neuronal development in Drosophila

  Jyoti Singh, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-Vg (1:100), rabbit anti DCP-1 (1:100, 9578) was procured from Cell Signaling Technology, rabbit anti-HA (1:100 ...