Labshake search

101 - 150 of 1181 citations for Ethyl 6 2 morpholinomethyl phenyl 6 oxohexanoate since 2020

• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... SOX-2 (Cell Signaling; #4900S), βIII-tubulin (Abcam ...
• Cell autonomous requirement of imprinted XCI in extra-embryonic polar trophoblast cells

  Feng Wang, et al., bioRxiv - Developmental Biology 2022

  Quote: ... pErk1/2 (Cell Signaling #9102), Fgfr2 (Abcam 10648) ...
• Site-1 Protease inhibits mitochondrial metabolism by controlling the TGF-β target gene MSS51

  Muhammad G. Mousa, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Smad 2 (5339, Cell Signaling); Phospho-AKT (4060 ...
• COMBINATION THERAPIES TARGETING ALK-ABERRANT NEUROBLASTOMA IN PRECLINICAL MODELS

  Elizabeth R. Tucker, et al., bioRxiv - Cancer Biology 2022

  Quote: ... pERK1/2 (Cell Signaling #9101), AKT (Cell Signaling #9272) ...
• Resistance to PSEN1-selective γ-secretase inhibitors in T-cell acute lymphoblastic leukemia

  Charlien Vandersmissen, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PEN-2 (#8598, Cell signaling), nicastrin (9C3 ...
• Keratinocyte desmosomal cadherin Desmoglein 1 as a mediator and target of paracrine signaling in the melanoma niche

  Hope E. Burks, et al., bioRxiv - Cancer Biology 2022

  Quote: ... total ERK1/2 (Cell Signaling). The rabbit monoclonal antibody EP1576Y (ab52642 ...
• Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors

  Damien M. Rasmussen, et al., bioRxiv - Biophysics 2023

  Quote: ... and ERK1/2 (Cell Signaling). Membranes were washed and incubated for 1 h at RT with corresponding species-reactive secondary antibody and then imaged using an Odyssey CLx near-infrared imager (LI-COR Biosciences).
• The Role of Alpha-Synuclein in Synucleinopathy: Impact on Lipid Regulation at Mitochondria–ER Membranes

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2024

  Quote: ... ERLIN-2 (Cell Signaling; 2959S), protein kinase C (Sigma-Aldrich ...
• YAP dysregulation triggers hypertrophy by CCN2 secretion and TGFβ uptake in human pluripotent stem cell-derived cardiomyocytes

  Orlando Chirikian, et al., bioRxiv - Cell Biology 2024

  Quote: ... pMST1/2 (Cell Signaling 49332) and GAPDH (Proteintech-60004-1 ...
• Targeted KRAS^G12V degradation elicits efficient and durable lung adenocarcinoma regression in vivo

  Alberto Martín, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pERK1/2 (Cell Signaling, 9101), Phospho-S6 Ribosomal Protein Ser240/244 (Cell Signaling ...
• Prohibitin 2 is a Key Regulator of T Cell Proliferation and Effector Functions

  Johannes F. Vogt, et al., bioRxiv - Immunology 2024

  Quote: ... Erk1/2 (Cell Signaling #9102), p-Erk1/2 (Cell Signaling #9106) ...
• Abl kinases regulate FGF signaling independent of Crk phosphorylation to prevent Peters anomaly

  Hao Wu, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Erk1/2 (Cell Signaling, #4695), Abl (BD Pharmingen ...
• Endothelial Rho kinase controls blood vessel integrity and angiogenesis

  Martin Lange, et al., bioRxiv - Developmental Biology 2024

  Quote: ... pPAK1/2 (Cell Signaling, #2605S), PAK1/2/3 (Cell Signaling ...
• Endothelial Rho kinase controls blood vessel integrity and angiogenesis

  Martin Lange, et al., bioRxiv - Developmental Biology 2024

  Quote: ... pLIMK1/2 (Cell Signaling, # 3841S), LIMK1 (Cell Signaling ...
• TRIM5α restriction of HIV-1-N74D viruses in lymphocytes is caused by a loss of cyclophilin A protection

  Anastasia Selyutina, et al., bioRxiv - Microbiology 2020

  Quote: ... and activated with IL-2 (100 U/ml) (Human IL-2; Cell Signaling Technology, #8907SF) and phytohemagglutinin (1 µg/ml ...
• Preserving endothelial integrity in human saphenous veins during preparation for coronary bypass surgery

  Meghan W. Sedovy, et al., bioRxiv - Physiology 2023

  Quote: ... and nuclear factor erythroid 2-related factor 2 (NRF2, #12721, 1:25, Cell Signaling Technology). Antibody binding was identified by incubation with goat anti-rabbit or anti-mouse secondary antibodies (Thermo Fisher Scientific ...
• Calcium-Mediated Modulation of Blood-Brain Barrier Permeability by Laser Stimulation of Endothelial-Targeted Nanoparticles

  Xiaoqing Li, et al., bioRxiv - Bioengineering 2022

  Quote: ... P-p44/42 ERK1/2 and p44/42 ERK1/2 were purchased from Cell Signaling Technology. Gold (III ...
• Radiation-Induced Changes in Energy Metabolism Result in Mitochondrial Dysfunction in Salivary Glands

  Lauren G. Buss, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and anti-extracellular signal-regulated protein kinases 1/2 (ERK1/2) (p44/42 MAPK, Cell Signaling). For detection ...
• Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice

  Sreeram Vallabhaneni, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-ERK1/2 (Cell signaling, CST4695), anti-phospho-ERK1/2 (Cell Signaling ...
• Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

  Jill E. Hunter, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK 1/2 (9102 Cell Signaling), AKT (phospho S473 ...
• BRD4-mediated repression of p53 is a target for combination therapy in AML

  Anne-Louise Latif, et al., bioRxiv - Cell Biology 2020

  Quote: ... BCL-2 (Cell signaling, 2870, RRID:AB_2290370) (Supplementary Table 6) ...
• Gain-of-function mutation in Gli3 causes ventricular septal defects

  Antonia Wiegering, et al., bioRxiv - Developmental Biology 2020

  Quote: ... pMEK1/2 (#9121; Cell Signaling Technology), acetylated α-tubulin (#sc-23950 ...
• PD-1-induced T cell exhaustion is controlled by a Drp1-dependent mechanism

  Luca Simula, et al., bioRxiv - Immunology 2021

  Quote: ... anti-ERK1/2 (Cell Signaling 4695), anti-Hsp90 (Cell Signaling 4877) ...
• Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

  Brian Czaya, et al., bioRxiv - Cell Biology 2021

  Quote: ... Phospho- ERK1/2 (9101, Cell Signaling), phospho-STAT3 (9145 ...
• Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells via modulating metabolism and death pathways

  J Vial, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-ERK1/2 (9102, Cell signaling), anti-mTOR (2983 ...
• Chronic high dietary sucrose induces sexually dimorphic metabolic adaptations in liver and adipose tissue

  Erin J Stephenson, et al., bioRxiv - Physiology 2020

  Quote: ... ACC1/2 (#3676S, Cell Signaling Technology), phospho-ACC1/2 Ser79 (#3661 ...
• PAK1 and PAK2 in cell metabolism regulation

  Tereza Kořánová, et al., bioRxiv - Cell Biology 2021

  Quote: ... PAK1/2/3 (Cell Signaling, #2604), and β-actin (Sigma–Aldrich ...
• Pseudomonas aeruginosa Stimulates Inflammation and Enhances KSHV-Induced Cell Proliferation and Cellular Transformation through Both LPS and Flagellin

  Ashley Markazi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (4695S, Cell Signaling Technology), phospho-ERK1/2 (4370S ...
• The Mechanism of Neurite Outgrowth Induction by Novel Synthetic Retinobenzoic Acids

  Yang Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... phospho-ERK1/2 (Cell Signaling Technology), or phospho-mTOR (Cell Signaling Technology ...
• IKK2/NFkB signaling controls lung resident CD8 T cell memory during influenza infection

  Curtis J. Pritzl, et al., bioRxiv - Immunology 2022

  Quote: ... phosphorylated ERK1/2 from Cell Signaling; anti-SMAD7(293739 ...
• Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFкB p50 recruitment, and H3K9me2 deposition

  Veronica Elizabeth Burns, Tom Klaus Kerppola, bioRxiv - Immunology 2022

  Quote: ... αlaminB1 (Cell Signaling 13435, lot 2), normal rabbit IgG (Santa Cruz sc-2027 ...
• Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFкB p50 recruitment, and H3K9me2 deposition

  Veronica Elizabeth Burns, Tom Klaus Kerppola, bioRxiv - Immunology 2022

  Quote: ... αG9a (Cell Signaling 3306, lot 2), αGLP (Abcam ab41969 ...
• TCF-7 is dispensable for anti-tumor response but required for persistent function of mature CD8 T cells

  Rebecca Harris, et al., bioRxiv - Immunology 2022

  Quote: ... JAK 2(Cell Signaling Technology # 3230), JAK3 (Cell Signaling Technology #8863) ...
• TCF-7 is dispensable for anti-tumor response but required for persistent function of mature CD8 T cells

  Rebecca Harris, et al., bioRxiv - Immunology 2022

  Quote: ... ERK1-2 (Cell Signaling Technology #9107), JAK 2(Cell Signaling Technology # 3230) ...
• YTHDF1 drives intestinal immune response against bacterial infection

  Xin Zong, et al., bioRxiv - Immunology 2020

  Quote: ... ERK1/2 (Cell Signaling Technology, 9102), phospho-ERK1/2 (HuaAn ...
• AMPK-dependent phosphorylation is required for transcriptional activation of TFEB/TFE3

  Mathieu Paquette, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ACC1/2 (Cell Signaling Technology, 3676), p-ACC1/2 (S79 ...
• 17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

  Samim Ali Mondal, et al., bioRxiv - Physiology 2022

  Quote: ... MMP-2 (Cell Signaling; 1:1000), TIMP-1 (Sino Biological ...
• Genetic or transcranial magnetic stimulation of B-RAF–MEK signaling promotes CST axon sprouting and functional regeneration

  Francesco Boato, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-pMEK1/2 (Cell Signaling, 9121), anti-AKT (Cell Signaling ...
• A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions

  Damien Detraux, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-ERK1/2 (Cell Signaling 9102), anti-phosphoERK1/2 (Cell Signaling 9101 ...
• A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions

  Damien Detraux, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-phosphoERK1/2 (Cell Signaling 9101) and anti-SMAD2/3 (Cell Signaling 8685).
• Canonical and noncanonical TGF-β signaling regulate fibrous tissue differentiation in the axial skeleton

  Sade W. Clayton, Ga I Ban, Cunren Liu, Rosa Serra, bioRxiv - Developmental Biology 2020

  Quote: ... ERK1/2 Catalog #4695S (Cell Signaling), pp38 Catalog #9211S (Cell Signaling) ...
• Canonical and noncanonical TGF-β signaling regulate fibrous tissue differentiation in the axial skeleton

  Sade W. Clayton, Ga I Ban, Cunren Liu, Rosa Serra, bioRxiv - Developmental Biology 2020

  Quote: ... pERK1/2 Catalog #9101S (Cell Signaling), ERK1/2 Catalog #4695S (Cell Signaling) ...
• Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/P38 signaling

  Jamie L. Grit, et al., bioRxiv - Genomics 2020

  Quote: ... phospho-ERK1/2 (Cell Signaling #9101), and β-Actin (Cell Signaling #3700) ...
• GP96 drives exacerbation of secondary bacterial pneumonia following influenza A virus infection

  Tomoko Sumitomo, et al., bioRxiv - Microbiology 2020

  Quote: ... Calpain 2 (Rabbit-pAb, Cell Signaling), or serotype 2 capsule (Rabbit ...
• Unbiased and UMI-informed sequencing of cell-free miRNAs at single-nucleotide resolution

  M.A.J. van Eijndhoven, et al., bioRxiv - Genomics 2021

  Quote: ... Argonaute 2 (#2987; Cell Signaling Technology) and β-Actin (sc-47778 ...
• KRAS G12D can be targeted by potent salt-bridge forming inhibitors

  Zhongwei Mao, et al., bioRxiv - Cancer Biology 2021

  Quote: ... pERK1/2 (Cell Signaling Technology, 4370), ERK1/2 (Cell Signaling Technology ...
• KRAS G12D can be targeted by potent salt-bridge forming inhibitors

  Zhongwei Mao, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (Cell Signaling Technology, 4695), pAKT(Thr308 ...
• SARS-CoV-2 desensitizes host cells to interferon through inhibition of the JAK-STAT pathway

  Da-Yuan Chen, et al., bioRxiv - Microbiology 2020

  Quote: ... pSTAT-2 (Cell Signaling Technologies; #4441), STAT2 (Santa Cruz Biotechnology ...
• FGFR Signaling Coordinates the Balance Between Glycolysis and Fatty Acid β-Oxidation in Lymphatic Endothelial Cells

  Hongyuan Song, Jie Zhu, Longhou Fang, Pengchun Yu, bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 (Cell Signaling Technology, 4695), CPT1A (Abcam ...
• Nutrient Sensing Receptor GPRC6A Regulates mTORC1 Signaling and Tau Biology

  Chao Ma, et al., bioRxiv - Neuroscience 2024

  Quote: ... ERK1/2 (Cell Signaling Tech, #9102S), ERK1/2 pT202/Y204 (Cell Signaling Tech ...