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1351 - 1400 of 10000+ citations for 7 Chloro 1 3 dihydro 1 methyl 5 phenyl 2H benzo 1 4 diazepin 2 one 4 oxide since 2019

• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (4695, 1:1000, Cell Signaling Technology), Phospho-p44/42 MAPK (Erk1/2 ...
• Engineering Regionally-Activated Drugs for Neuroscience

  Zhimin Huang, et al., bioRxiv - Bioengineering 2023

  Quote: ... (2) incubate with primary rabbit anti-c-Fos (1:2000, 2250S, Cell Signaling Technology) and chicken antityrosine hydroxylase (1:2000 ...
• Engineering Regionally-Activated Drugs for Neuroscience

  Zhimin Huang, et al., bioRxiv - Bioengineering 2023

  Quote: ... (2) incubate with primary rabbit anti-c-Fos (1:2000, 2250S, Cell Signaling Technology) antibody in PBS with 0.3% Triton-X for 2h at room temperature ...
• E-cadherin-dependent phosphorylation of EGFR governs a homeostatic feedback loop controlling intercellular junction viscosity and collective migration modes

  Chaoyu Fu, et al., bioRxiv - Cell Biology 2023

  Quote: ... Phospho-Myosin Light Chain 2 (Ser19) antibody (3671, Cell Signaling Technologies, diluted 1:50) according to the manufacturer’s instructions ...
• Dormancy-inducing 3D-engineered matrix uncovers mechanosensitive and drug protective FHL2-p21 signaling axis

  Sadra Bakhshandeh, et al., bioRxiv - Bioengineering 2024

  Quote: ... and anti-phospho-p44/42 MAPK (p-ERK1/2) (1:200, #9101S, Cell Signaling). The secondary antibodies are ...
• Oseltamivir (Tamiflu), a Commonly Prescribed Antiviral Drug, Mitigates Hearing Loss in Mice

  Emma Sailor-Longsworth, et al., bioRxiv - Neuroscience 2024

  Quote: ... or antibody anti-pERK1/2 (Thr202/Tyr204, 1:400 dilution, 9101, Cell Signaling Technology) and imaged with a confocal microscope (LSM 700 ...
• Pervasive promoter hypermethylation of silenced TERT alleles in human cancers

  D Esopi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or 4 μL IgG (2729, Cell Signaling). Dynabead Protein G beads (30 μL ...
• ZO-1 regulates Hippo-independent YAP activity and cell proliferation via a GEF-H1- and TBK1-regulated mechanosensitive signalling network

  Alexis J. Haas, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit polyclonal (3013, Lot 4, Cell Signaling); phospho-Ser172 TBK1 ...
• TRIPLE-NEGATIVE BREAST CANCER CELLS RECRUIT NEUTROPHILS BY SECRETING TGF-β AND CXCR2 LIGANDS

  Shuvasree SenGupta, et al., bioRxiv - Immunology 2021

  Quote: ... blocked with 5% nonfat dry milk for 1 hr and probed with primary Abs: phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204, dilution 1:2000, Cell Signaling Technology cat. no. 4370) and alpha tubulin (dilution 1:2000 ...
• Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response

  Johanna L. Mehl, et al., bioRxiv - Cell Biology 2022

  Quote: ... and incubated overnight with primary antibodies (1:500 pSTAT1, 7649 Cell Signaling; 1:500 pSTAT3, 9145 Cell Signaling; 1:500 pSTAT5, 9359S Cell Signaling; 1:500 STAT1, 9172 Cell Signaling; 1:500 STAT3 ...
• ECM degradation in the stump region induced by Fgf during functional joint regeneration in frogs

  Haruka Matsubara, Takeshi Inoue, Kiyokazu Agata, bioRxiv - Developmental Biology 2023

  Quote: ... diluted 1:100), Rat anti-GFP monoclonal antibody (nacalai tesque, GF090R, diluted 1:1000) and rabbit anti-pSmad1/5/9 antibody (Cell Signaling Technology, #13820, diluted 1:100). After the primary antibody incubation ...
• Stiffness of Nanoparticulate Mineralized Collagen Scaffolds Triggers Osteogenesis via Mechanotransduction and Canonical Wnt Signaling

  Qi Zhou, et al., bioRxiv - Bioengineering 2020

  Quote: ... Sections were then separately incubated with anti-p-Smad1/5 (1:500, Cell Signaling Technologies), anti-Yap (1:200 ...
• Base editor scanning charts the DNMT3A activity landscape

  Nicholas Z. Lue, et al., bioRxiv - Biochemistry 2022

  Quote: ... H3K36me2 (10 × 106 cells, 1 μg anti-H3K36me2, Cell Signaling Technologies, Cat#2901, Lot#5). Dynabeads Protein G (Thermo Fisher Scientific ...
• TRPM2 deficiency protects against atherosclerosis by inhibiting TRPM2-CD36 inflammatory axis in macrophages

  Pengyu Zong, et al., bioRxiv - Physiology 2021

  Quote: ... Rabbit polyclonal antibodies to CD36 (D8L9T) (Cell Signaling Technology, 14347S, 1:1000 in 5% BSA); Rabbit polyclonal antibodies to Fyn (Cell Signaling Technology ...
• TRPM2 deficiency protects against atherosclerosis by inhibiting TRPM2-CD36 inflammatory axis in macrophages

  Pengyu Zong, et al., bioRxiv - Physiology 2021

  Quote: ... Rabbit polyclonal antibodies to MIF (E7T1W) (Cell Signaling Technology, 87501, 1:1000 in 5% BSA); Rabbit polyclonal antibodies to CD36 (D8L9T ...
• Chemoproteomic study uncovers HemK2/KMT9 as a new target for NTMT1 bisubstrate inhibitors

  Dongxing Chen, et al., bioRxiv - Biochemistry 2021

  Quote: ... HRP-linked antibody (1:1000 dilution in 5% BSA in TBST buffer, Cell signaling #7074) was incubated at 4 °C for 1h ...
• Nanoligomers targeting NF-κB and NLRP3 reduce neuroinflammation and improve cognitive function with aging and tauopathy

  Devin Wahl, et al., bioRxiv - Physiology 2024

  Quote: ... followed by HRP-conjugated secondary antibodies (TST-T in 5% milk; 1:5000; Cell Signaling) for 1 h ...
• Lineage transcription factors co-regulate subtype-specific genes providing a roadmap for systematic identification of small cell lung cancer vulnerabilities

  Karine Pozo, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-NKX2-1 (1:2000; Cell Signaling Technology 12373), rabbit anti-PROX1 (1:2000 ...
• Electro-acupuncture Alleviates METH Withdrawal-induced Spatial Memory Deficits by Restoring Astrocyte-drived Glutamate Uptake in dCA1

  Pengbo Shi, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-GLT-1 (1:300; Cell Signaling Technology, USA), rabbit anti-GLAST (1:300 ...
• Intracellular Staphylococcus aureus perturbs the host cell Ca²⁺-homeostasis to promote cell death

  Kathrin Stelzner, et al., bioRxiv - Microbiology 2020

  Quote: ... Antibodies against Calpain 1 (1:1000, #2556, Cell signaling Technology), Calpain 4 (1:500 ...
• Dorsal horn CGRP-expressing interneurons contribute to nerve injury-induced mechanical hypersensitivity

  LS Löken, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-Fos (1:5000, Calbiochem; 1:2000, Cell Signaling), guinea pig anti-Fluorogold (1:1000 ...
• Synapsin-caveolin-1 mitigates cognitive deficits and neurodegeneration in Alzheimer’s disease mice

  Shanshan Wang, et al., bioRxiv - Neuroscience 2020

  Quote: ... and rabbit anti- Cav-1 (1:1000, Cell Signaling, USA) at 4°C overnight ...
• The DNA Damage response and cell competition are p53- and Xrp1-dependent processes that suppress hyperplastic aneuploidy

  Chaitali Khan, Nicholas E. Baker, bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-cleaved Dcp-1 (Cell Signaling 9578, 1:200), mouse anti-γH2Av (DSHB UNC93-5.2.1 ...
• Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival

  K. Pfeifer, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rb-anti-Dcp-1 (1:50; Cell Signaling Technology #9578), Developmental Studies Hybridoma Bank ...
• β-Catenin-NFκB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction

  Shikai Hu, et al., bioRxiv - Pathology 2021

  Quote: ... Histone H3 (Cell Signaling, 9715, 1:1000 in 1% milk). Membranes were washed in Blotto buffer and incubated with the appropriate HRP-conjugated secondary antibody for 75 minutes at room temperature ...
• Overexposure to apoptosis via disrupted glial specification perturbs Drosophila macrophage function and reveals roles of the CNS during injury

  Emma Louise Armitage, et al., bioRxiv - Immunology 2020

  Quote: ... Rabbit anti-cDCP-1 (9578S 1:1000; Cell Signaling Technologies), mouse anti-Repo (concentrate of clone 8D12 used at 1:1000 ...
• KANSL1 Deficiency Causes Neuronal Dysfunction by Oxidative Stress-Induced Autophagy

  Katrin Linda, et al., bioRxiv - Neuroscience 2020

  Quote: ... p-ULK1 (1:1000; Ser757) (1:1000; Cell Signaling 14202), and LAMP1 (1:200 ...
• Targeting of MCL-1 in breast cancer associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties

  TL Bonneaud, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Mcl-1 (1:800, Cell Signaling Technology, Danvers, MA, USA); Vimentin (1:100 ...
• Ankyrin-B is lipid-modified by S-palmitoylation to promote dendritic membrane scaffolding of voltage-gated sodium channel Nav1.2 in neurons

  Julie P. Gupta, Paul M. Jenkins, bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Flotillin-1 antibody (Cell Signaling Technologies, 1:1000), rabbit/mouse anti-HA antibody (Cell Signaling Technologies ...
• Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity

  Claudia Feriotti, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-caspase-1 (anti-rabbit, 1:1000; #24232, Cell Signaling), anti-AIM2 (anti-rabbit ...
• Targeting the Src pathway enhances the efficacy of selective FGFR inhibitors in cancers with FGFR3 alterations

  Nadia Carvalho Lima, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Anti-rabbit HRP (7074) 1:2000-1:10,000 (Cell Signaling) and anti-mouse HRP (G32-62G-1000 ...
• Neuronal octopamine signaling regulates mating-induced germline stem cell proliferation in female Drosophila melanogaster

  Yuto Yoshinari, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit cleaved Dcp-1 (Cell Signaling Technology #9578; 1:100), rat anti-Vasa (DSHB ...
• Lineage reversion drives WNT independence in intestinal cancer

  Teng Han, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-ETS-1 (1:1000, Cell Signaling Technologies, #14069), rabbit anti-GAPDH (1:1000 ...
• Selective localization of Mfn2 near PINK1 enable its preferential ubiquitination by Parkin on mitochondria

  Marta Vranas, et al., bioRxiv - Biochemistry 2021

  Quote: ... rabbit anti-mitofusin 1 (1:100, mAb 13196S, Cell Signaling), rabbit anti-Miro1 (1:50 ...
• KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance

  Anastasia-Maria Zavitsanou, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-PD-1 (D4W2J, Cell Signaling Technology, 1/200, Opal520), anti-Foxp3 (236A/E7 ...
• Condensation of the Drosophila Nerve Cord is Oscillatory and depends on Coordinated Mechanical Interactions

  Katerina Karkali, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-Dcp-1 (Asp216) (1:100, Cell Signaling #9578), rabbit anti-GFP tag polyclonal (1:600 ...
• Direct control of translational elongation by TAOK2β highlights altered protein synthesis as a fundamental underlying component of autism

  Melad Henis, et al., bioRxiv - Neuroscience 2022

  Quote: ... (Cell Signaling Technology; 2278, WB 1:1,000, ICC 1:300); rabbit anti-IgG (Millipore ...
• RhoA activation promotes glucose uptake to elevate proliferation in MAPK inhibitor resistant melanoma cells

  Vasanth Siruvallur Murali, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Insulin receptor substrate 1 1:1000(Cell Signaling Technology, 2383L), Ser636/639 Phospho-Insulin receptor substrate 1 (Cell Signaling Technology ...
• Caspase cleavage of Influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production

  Carmen Figueras-Novoa, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit polyclonal PARP-1 (Cell Signaling, 9542, WB 1:1000).
• Protective role of Pten downregulation in Huntington’s Disease models

  Nisha, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Dcp-1 (1:100; 9578; Cell Signaling Technology, USA), anti-Dlg1 (1:100 ...
• Activation of intestinal immunity by pathogen effector-triggered aggregation of lysosomal TIR-1/SARM1

  Samantha Y. Tse-Kang, et al., bioRxiv - Immunology 2024

  Quote: ... 1:1000 phospho p38 PMK-1 (Cell Signaling Technology, #9211), 1:1000 total PMK-1,45 1:2000 mouse monoclonal anti-alpha-Tubulin (Sigma ...
• Lysosomal integrity suppresses TIR-1/SARM1 aggregation to restrain toxic propagation of p38 innate immunity

  Samantha Y. Tse-Kang, Read Pukkila-Worley, bioRxiv - Immunology 2024

  Quote: ... 1:1000 phospho p38 PMK-1 (Cell Signaling Technology, #9211), 1:1000 total PMK-1,23 1:2000 mouse monoclonal anti-alpha-Tubulin (Sigma ...
• The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle atrophy

  Yurika Ito, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-TRA-1-81 (diluted 1:200, Cell Signaling Technology), anti-NANOG (diluted 1:200 ...
• N-glycosylation engineering in chimeric antigen receptor T cells enhances anti-tumor activity

  Elien De Bousser, et al., bioRxiv - Immunology 2023

  Quote: ... monoclonal rabbit anti-galectin-1 (1:200, Cell Signaling, 13888S) or monoclonal rabbit anti-galectin-3 (1:200 ...
• IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A

  Magdalena Gebert, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-XBP-1 (S) (1:1000, D2C1F, Cell Signaling). After the washing steps ...
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-human caspase-1 (1:1,000, #3866, Cell Signaling Technology), anti-caspase-1 (1:1,000 ...
• In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

  Jerry J. Fan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-Caveolin-1 (Cell Signaling Technology #3267, 1:400), rabbit anti-Clathrin Heavy Chain (Cell Signaling Technology #4796 ...
• In vivo functional genomics identifies essentiality of potassium homeostasis in medulloblastoma

  Jerry J. Fan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-Caveolin-1 (Cell Signaling Technology #3267, 1:200), rabbit anti-DCX (abcam #ab18723 ...
• Regenerative growth is constrained by brain tumor to ensure proper patterning in Drosophila

  Syeda Nayab Fatima Abidi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and anti-cleaved Dcp-1 (1:250)(Cell Signaling #9578). The Developmental Studies Hybridoma Bank (DSHB ...
• Stress-induced Rab11a-exosomes induce AREG-mediated cetuximab resistance in colorectal cancer

  John D. Mason, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-Caveolin-1 (Cell Signaling Technology #3238, 1:500), goat anti-AREG (R&D Systems #AF262 ...