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1351 - 1400 of 10000+ citations for 6 METHOXY ISOCHROMAN 1 ONE since 2019

• Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targeting of WRN and ATR

  Dali Zong, et al., bioRxiv - Cancer Biology 2023

  Quote: ... pATR (T1989, 1:500, Cell Signaling), pCHK1 (S345 ...
• An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes

  Simone Caielli, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Caspase 1 (Cell Signaling #24232S), anti-polγ (Abcam #ab128899) ...
• Synaptopodin is required for long-term depression at Schaffer collateral-CA1 synapses

  Yanis Inglebert, et al., bioRxiv - Neuroscience 2023

  Quote: ... IP3R (1:1000, Cell Signaling, D53A5). Horseradish peroxidase (HRP)-conjugated secondary antibodies goat anti-rabbit (abcam ...
• TPPP Forms Liquid Condensates and Aggregates in Multiple System Atrophy

  Shahrnaz Kemal, et al., bioRxiv - Neuroscience 2023

  Quote: ... GFAP (Cell Signaling 123895, 1:400), MBP (Abcam ab7349 ...
• Aberrant activation of the innate immune sensor PKR by self dsRNA is prevented by direct interaction with ADAR1

  Ketty Sinigaglia, et al., bioRxiv - Immunology 2023

  Quote: ... eIF2α 1:1,000 (Cell signaling, #9722), Rig-I 1:500 (Cell Signaling ...
• DNA-guided transcription factor cooperativity shapes face and limb mesenchyme

  Seungsoo Kim, et al., bioRxiv - Genomics 2023

  Quote: ... CTCF (Cell Signaling, 2899, 1:25), V5 (Abcam ...
• DNA-guided transcription factor cooperativity shapes face and limb mesenchyme

  Seungsoo Kim, et al., bioRxiv - Genomics 2023

  Quote: ... AP2a (Cell Signaling, 3215, 1:25), CTCF (Cell Signaling ...
• Systemic Lupus Erythematosus Serum Stimulation of Human Intestinal Organoids Induces Changes in Goblet Cell Differentiation and Mitochondrial Fitness

  Inga Viktoria Hensel, et al., bioRxiv - Cell Biology 2023

  Quote: ... β-actin (1:500; Cell Signaling #4970S), STAT1 (1:1000 ...
• Systemic Lupus Erythematosus Serum Stimulation of Human Intestinal Organoids Induces Changes in Goblet Cell Differentiation and Mitochondrial Fitness

  Inga Viktoria Hensel, et al., bioRxiv - Cell Biology 2023

  Quote: ... STAT1 (1:1000; Cell Signaling #9167S) or IFIT3 (1:500 ...
• Nuclear MTHFD2 secures mitosis progression by preserving centromere integrity

  Natalia Pardo-Lorente, et al., bioRxiv - Cell Biology 2023

  Quote: ... Vinculin (Cell Signaling; #13901S; 1:1000), FDX1 (Thermo Fisher Scientific ...
• Cofilin-Driven Nuclear Deformation Drives Dendritic Cell Migration through the Extracellular Matrix

  Harry Warner, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (Cell Signaling 2118, 1:500), Myosin 9 HC (Thermofisher 5D9D2 ...
• Divergent Proteome Reactivity Influences Arm-Selective Activation of Pharmacological Endoplasmic Reticulum Proteostasis Regulators

  Gabriel M. Kline, et al., bioRxiv - Biochemistry 2023

  Quote: ... mouse GAPDH (1:1000) (Cell Signaling), Goat anti-rabbit IRdye 800-cw (Licor ...
• Oxygen-independent, hormonal control of HIF-1α regulates the developmental and regenerative growth of cardiomyocytes

  Amarylis C.B.A. Wanschel, et al., bioRxiv - Developmental Biology 2023

  Quote: ... AMPKα (1:2000; 5831S, Cell signaling), Thr172-phospho-AMPKα (1:2000 ...
• Group A Streptococcus Induces Lysosomal Dysfunction in THP-1 Macrophages

  Scott T. Nishioka, et al., bioRxiv - Microbiology 2023

  Quote: ... LAMP-1 (Cell Signaling Technology, #9091), V1A (Abnova ...
• Platelet pannexin-1 channels modulate inflammation during abdominal aortic aneurysm formation

  Lisa Maria Metz, et al., bioRxiv - Cell Biology 2022

  Quote: ... GAPDH (#2118S, Cell Signaling, 1:1000) served as loading control ...
• Extracellular vesicles and co-isolated endogenous retroviruses differently affect dendritic cells

  Federico Cocozza, et al., bioRxiv - Cell Biology 2023

  Quote: ... Argonaute2 1/1000 (Cell Signaling, 2897), MHC I 1/1000 (rabbit-anti-mouse MHCI ...
• Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier

  Stephanie L. Baringer, et al., bioRxiv - Cell Biology 2023

  Quote: ... TfR (Cell Signaling, 13208S, 1:500), Tf (Abcam ...
• TGFB1 Induces Fetal Reprogramming and Enhances Intestinal Regeneration

  Lei Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... OLFM4 (Cell Signaling 39141, 1:2500), CD44 (BD 558739 ...
• TGFB1 Induces Fetal Reprogramming and Enhances Intestinal Regeneration

  Lei Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... SOX9 (Cell Signaling 82630, 1:100) and DAPI (Biotium 40043 ...
• Oncogenic Kras^G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8⁺ T cells dependent manner

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD19 (Cell Signaling 3574s; 1:100), CD8 (Cell Signaling 85336S ...
• Oncogenic Kras^G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8⁺ T cells dependent manner

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... pERK (Cell Signaling 4376S, 1:250), diluted in blocking buffer overnight at 4 °C or for 3 hours at room temperature ...
• Oncogenic Kras^G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8⁺ T cells dependent manner

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD8 (Cell Signaling 85336S, 1:300), CD11b (Abcam ab133357 ...
• Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance

  Fei Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... H3K36me2 (1:1,000, 2901; Cell Signaling), H3K36me3 (1:2,000 ...
• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... p38 (total, Cell Signaling, 1:1000), pan – OXPHOS (ATP5A1 ...
• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... XBP1s (Cell Signaling, D2C1F, 1:1000), PARP (Cell Signaling ...
• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... ATF4 (Cell Signaling, D4B8, 1:1000).
• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... IRE1α (Cell Signaling, 14C10, 1:1000), β-tubulin ...
• MYC enhancer invasion promotes prognostic cancer type-specific gene programs through an epigenetic switch

  Simon T. Jakobsen, et al., bioRxiv - Genomics 2023

  Quote: ... MYC (Cell Signaling, 13987, 1:1000), β-tubulin (Sigma Aldrich ...
• MYC enhancer invasion promotes prognostic cancer type-specific gene programs through an epigenetic switch

  Simon T. Jakobsen, et al., bioRxiv - Genomics 2023

  Quote: ... H3 (Cell Signaling, 2650, 1:2500), H3K9ac (Abcam ...
• Myddosome clustering in IL-1 receptor signaling regulates the formation of an NF-kB activating signalosome

  Fakun Cao, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1:400 (Cell Signaling Technology, #2697); anti-M1-Ub ...
• Morphological changes and two Nodal paralogs drive left-right asymmetry in the squamate veiled chameleon (C. calyptratus)

  Natalia A. Shylo, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1:500 (Cell Signaling Technology 3108S); and Arl13b 1:2000 (Proteintech 17711-1-AP)] in blocking solution overnight at 4°C ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (5174S, Cell Signaling, 1/10000), HtrA2 (#9745 ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... TOMM20 (42406, Cell Signaling, 1:2000), TOM40 (18409-1-AP ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ... HtrA2 (#9745, Cell Signaling, 1/1000), OMA1 (HPA055120 ...
• Cytosolic retention of the mitochondrial protease HtrA2 during mitochondrial protein import stress (MPIS) triggers the DELE1-HRI pathway

  Paul Y. Bi, et al., bioRxiv - Cell Biology 2023

  Quote: ATF4 (11815S, Cell Signaling, 1/2000), DELE1(PA5-57712 ...
• FBXO42 activity is required to prevent mitotic arrest, spindle assembly checkpoint activation, and lethality in glioblastoma and other cancers

  Pia Hoellerbauer, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Tp53 (Cell Signaling #48818, 1:500), αTubulin (Sigma #T9026 ...
• The multimodal action of G alpha q in coordinating growth and homeostasis in the Drosophila wing imaginal disc

  Vijay Velagala, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and DCP-1 (#9578S; Cell Signaling), diluted to 1:100 in 5% NGS ...
• The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis

  Bianca M. Lupan, et al., bioRxiv - Developmental Biology 2023

  Quote: ... CC3 (Cell Signaling, 9661, 1:250), PH3 (Millipore ...
• Multi-omics on truncating ASXL1 mutations in Bohring Opitz syndrome identify dysregulation of canonical and non-canonical Wnt signaling

  Isabella Lin, et al., bioRxiv - Genetics 2022

  Quote: ... H3K4me3 (Cell Signaling, #9751S, 1:50) and H3K27me3 (Cell Signaling ...
• FBXO42 activity is required to prevent mitotic arrest, spindle assembly checkpoint activation, and lethality in glioblastoma and other cancers

  Pia Hoellerbauer, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ΔActin (Cell Signaling #3700S, 1:2,000). The following secondary antibodies were used (LI-COR ...
• Myddosome clustering in IL-1 receptor signaling regulates the formation of an NF-kB activating signalosome

  Fakun Cao, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1:800 (Cell Signaling Technology, #3033); anti-phospho-IKK ...
• Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury

  Mary E. Mohr, et al., bioRxiv - Cell Biology 2023

  Quote: ... pMLKL (1:100, Cell Signaling, D6E3G), PTGS2 (1:100 ...
• NAD homeostasis maintained by NMNAT2 supports vesicular glycolysis and fuels fast axonal transport in distal axons of cortical glutamatergic neurons in mice

  Sen Yang, et al., bioRxiv - Neuroscience 2023

  Quote: ... Draq5 (1:10,000 dilution, Cell Signaling) or 4°,6-diamidino-2-phenylindole (DAPI ...
• BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation

  Samuel R. Witus, et al., bioRxiv - Biochemistry 2023

  Quote: ... Tubulin (2128S, Cell Signaling; 1:2000), Lamin B1 (SC374015 ...
• Liraglutide protects against diastolic dysfunction and improves ventricular protein translation

  Cody Rutledge, et al., bioRxiv - Physiology 2023

  Quote: ... 4EBP1 (1:1000, Cell Signaling, #9644), P62 (Invitrogen #PA5-20839 ...
• Liraglutide protects against diastolic dysfunction and improves ventricular protein translation

  Cody Rutledge, et al., bioRxiv - Physiology 2023

  Quote: ... S6 (1:1000, Cell Signaling, #2217), GAPDH (1:5000 ...
• Dissecting endocytic mechanisms reveals new molecular targets to enhance sodium iodide symporter activity with clinical relevance to radioiodide therapy

  Martin L. Read, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PICALM (1:1000; Cell Signaling Technology) and β-actin (1:2000 ...
• Oxygen-independent, hormonal control of HIF-1α regulates the developmental and regenerative growth of cardiomyocytes

  Amarylis C.B.A. Wanschel, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Cas9 (1:2000; 14697, Cell signaling), AMPKα (1:2000 ...
• Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin

  Stephanie L. Baringer, et al., bioRxiv - Neuroscience 2023

  Quote: ... IRP2 (Cell Signaling, 37135, 1:1000), FTH (Cell Signaling ...
• Amyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin

  Stephanie L. Baringer, et al., bioRxiv - Neuroscience 2023

  Quote: ... IRP1 (Cell Signaling, 20272, 1:1000), IRP2 (Cell Signaling ...