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1251 - 1300 of 3119 citations for 7 Chloro 1H pyrrolo 2 3 c pyridine since 2019

• High-Speed Low-Light In Vivo Two-Photon Voltage Imaging of Large Neuronal Populations

  Jelena Platisa, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-cleaved caspase-3 (Asp175) (9661; Cell Signaling; 1:250 dilution). Slices were then washed three times in 0.1 M PBS and incubated in secondary antibodies ...
• Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing

  Benedetta Artegiani, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-cleaved caspase-3 (Asp175) rabbit polyclonal 1:400 (Cell Signaling Technology #9661L), anti-E-cadherin mouse monoclonal 1:200 (BD bioscience #610182) ...
• Depletion of Ric-8B leads to reduced mTORC2 activity

  Maíra H. Nagai, et al., bioRxiv - Molecular Biology 2019

  Quote: ... followed by incubation with anti-cleaved caspase-3 (Cell Signaling #9661, 1:250) diluted in 1% FBS ...
• Platelet proteolytic machinery assessment in Alzheimer’s Diseases

  Roy G. Muriu, Jessica M. Sage, Abdulbaki Agbas, bioRxiv - Neuroscience 2019

  Quote: ... Cell signaling antibodies (Cell Signaling Technology, 3 Trask Lane, Danvers, MA 01923, USA): Anti-Beclin-1 (pAb ...
• Circadian Clock Core Component Bmal1 Dictates Cell Cycle Rhythm of Proliferating Hepatocytes during Liver Regeneration

  Huaizhou Jiang, et al., bioRxiv - Pathology 2021

  Quote: ... and glyceraldehyde 3-phosphate dehydrogenase (GADPH) (#5174) were purchased from Cell Signaling Technology; Bmal1 (SC-373955) ...
• Exosomal miR-106b-5p promotes Mtb survival via targeting CREB5 followed by SOAT1-CIDEC and CASP9-CASP3 pathway

  Haotian Chen, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-caspase-3(9662S)were acquired from Cell Signaling Technology (Beverly, MA, USA). Anti-CIDEC(PA1-4316)was purchased from Thermo Fisher Scientific ...
• Endothelial cells elicit a pro-inflammatory response to SARS-CoV-2 without productive viral infection

  Lilian Schimmel, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-cleaved caspase 3 (Cell Signaling, 9661 IF1:30 after pre-labeling), rabbit anti-GAPDH (Cell Signaling ...
• The ATF6β-calreticulin axis promotes neuronal survival under endoplasmic reticulum stress and excitotoxicity

  Dinh Thi Nguyen, et al., bioRxiv - Cell Biology 2021

  Quote: ... Primary antibodies against cleaved caspase-3 (Asp175, Cell Signaling Technology, Inc; 1:800) and βIII tubulin (MAB1637 ...
• Glucocorticoids Unmask Silent Non-Coding Genetic Risk Variants for Common Diseases

  Thanh Thanh Le Nguyen, et al., bioRxiv - Genomics 2022

  Quote: ... and Normal IgG Rabbit 2729 (Cell Signaling, lot 3, 0.49ug per 80ug chromatin). Quantitative PCR primers were designed with the NCBI Primers Blast Tools to ensure specificity of primers against the whole genome ...
• Biocompatible polymers for scalable production of human neural organoids

  Genta Narazaki, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Cleaved Caspase-3 (Asp175) (rabbit, Cell Signaling Technology, #9661, 1:200 dilution). Alexa Fluor dyes ...
• Hypoxia causes pancreatic β-cell dysfunction by activating a transcriptional repressor BHLHE40

  Tomonori Tsuyama, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) antibody (2118, Cell Signaling Technology, Danvers, MA), anti-HIF1α antibody (NB100-479 ...
• SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing

  Wenbo Liu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-Cleaved Caspase-3 (Asp175) antibody (#9661, Cell Signaling Technology, 1:200); and rabbit anti-Ki67 antibody (ab15580 ...
• QKI 6 ameliorates CIRI through promoting synthesis of triglyceride in neuron and inhibiting neuronal apoptosis associated with SIRT1-PPARγ-PGC-1α axis

  Rui Liu, et al., bioRxiv - Neuroscience 2020

  Quote: ... or anti-cleaved caspase-3 (D175; 1:1200; Cell Signaling Technology, Beverly, MA), β-Actin Mouse mAb (8H10D10 ...
• Lung type II alveolar epithelial cells collaborate with CCR2⁺ inflammatory monocytes in host defense against an acute vaccinia infection in the lungs

  Ning Yang, et al., bioRxiv - Immunology 2020

  Quote: ... Anti-glyceraldehyde-3-phosphate dehydrogenase (GADPH) or anti-β-actin antibodies (Cell Signaling) were used as loading controls.
• SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis

  Branden A. Smeester, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Cleaved caspase 3 (Asp175, clone D3E9) PE was purchased from Cell Signaling Technologies and cells were stained according to manufacturer’s recommendations ...
• AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication

  Kunihiko Yamashiro, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit-cleaved Caspase 3 (1:500, 9661S, Cell Signaling Technology, Danvers, MA, USA), rabbit-Calbindin (1:500 ...
• Diabetic phenotype in mouse and humans with β-amyloid pathology reduces the number of microglia around β-amyloid plaques

  Teemu Natunen, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-Caspase-3 (1:1000, #9662, Cell Signaling Technology, Danvers, MA, USA), mouse anti-phospho-ERK (1:500 ...
• FOXO1 represses Sprouty2 and Sprouty4 expression in endothelial cells to promote arterial specification and vascular remodeling in the mouse yolk sac

  Nanbing Li-Villarreal, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and incubated with antibodies to either Caspase 3 (Cell Signaling #9661, 1:50); Connexin37 (ThermoFisher Scientific #404200 ...
• Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

  Jennifer E. Kay, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Slides were then incubated with cleaved caspase-3 primary antibody (Cell Signaling Technology) for 60 minutes at room temperature ...
• Genetic Disruption of WASHC4 Drives Endo-lysosomal Dysfunction and Cognitive-Movement Impairments in Mice and Humans

  Jamie L. Courtland, et al., bioRxiv - Cell Biology 2020

  Quote: Primary antibodies: Rabbit anti-Cleaved Caspase-3 (Cell Signaling Technology #9661, 1:2000), Mouse anti-Calbindin (Sigma #C9848 ...
• Active growth signalling promotes cancer cell sensitivity to the CDK7 inhibitor ICEC0942

  G.A. Wilson, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Primary antibodies used anti Caspase 3 (Cell Signaling Technology 9662 rabbit 1:1000), anti Phospho-CDK1 (Thr161 ...
• Assessing the Cognitive Status of Drosophila by the Value-Based Feeding Decision

  Chih-Chieh Yu, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-cleaved Caspase-3 (1:200; Cell Signaling Technology 9661, RRID: AB_2341188), rat anti-Elav (1:100 ...
• The selective autophagy receptor p62 and the heat shock protein HSP27 facilitate lysophagy via the formation of phase-separated condensates

  Elizabeth R. Gallagher, Erika L.F. Holzbaur, bioRxiv - Cell Biology 2022

  Quote: ... rabbit monoclonal anti-GABARAP (E1J4E) (Cell Signaling, 13733, Lot: 3, WB: 1:1000); rabbit monoclonal anti-GABARAP+GABARAPL1+GABARAPL2 (Abcam ...
• High-fat diet feeding triggers a regenerative response in the adult zebrafish brain

  Yagmur Azbazdar, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-cleaved-Caspase-3 (1:400, 5A1E, Cell Signaling Technology, MA, USA) mouse anti-PCNA (1:200 ...
• P66Shc Mediates SUMO2-induced Endothelial Dysfunction

  Jitendra Kumar, et al., bioRxiv - Cell Biology 2024

  Quote: ... SUMO2/3 (Catalog no. 633306, Sigma and Catalog no. 4971, Cell Signaling Technologies); Monoclonal Ubc9 (D26F2 ...
• HuD (ELAVL4) gain-of-function impairs neuromuscular junctions and induces apoptosis in in vitro and in vivo models of amyotrophic lateral sclerosis

  Beatrice Silvestri, et al., bioRxiv - Neuroscience 2024

  Quote: ... fixed cells were incubated with anti-CC-3 (1:400, 9661, Cell signaling) overnight ...
• The Cyclin-Like Protein Spy1 Mediates Tumourigenic Potential of Triple Negative Breast Cancer

  Bre-Anne Fifield, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Primary antibodies were used as follows: cleaved caspase 3 (1:250; Cell Signaling) and phospho-histone H3 (1:300 ...
• Long noncoding RNA AL109754.1 Regulates Myeloid Dendritic Cell Differentiation and Potentiates TLR signaling

  Raza Ali Naqvi, Araceli Valverde, Afsar Naqvi, bioRxiv - Immunology 2023

  Quote: ... IRF3 (PE conjugated Rabbit mAb Phospho-IRF-3 [Ser396], clone: D6O1M, Cell Signaling).
• Targeting Ras signaling excitability in cancer cells through combined inhibition of FAK and PI3K

  Chao-Cheng Chen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and rabbit anti-human cleaved caspase 3 antibodies (Cell Signaling #9661, 1:800) at room temperature for 1 hour ...
• Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer

  Junghui Koo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ID-3 (#9837) and AKR1C2 (#13035) antibodies were purchased from Cell Signaling Technology. BMP6 (ab155963) ...
• Evolutionary diversification reveals distinct somatic versus germline cytoskeletal functions of the Arp2 branched actin nucleator protein

  Kaitlin A. Stromberg, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... though testes were stained with anti-cleaved caspase 3 (Asp 175, Cell Signaling) as done previously36 and probed with anti-rabbit secondary antibody (Alexa Fluor 488 ...
• Reduced glycolysis links resting zone chondrocyte proliferation in the growth plate

  Tatsuya Kobayashi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and anti-acetylate histone 3 lysine 9 (H3K9Ac) antibody (#9649, Cell Signaling Technology).
• Cytomegalovirus-induced inactivation of TSC2 disrupts the coupling of fatty acid biosynthesis to glucose availability resulting in a vulnerability to glucose limitation

  Matthew H. Raymonda, et al., bioRxiv - Microbiology 2023

  Quote: ... tuberin (TSC2; Santa Cruz Biotechnology, glyceraldehyde-3-phosphate dehydrogenase (GAPDH; Cell Signaling, 2118), anti-UL38 (8D6) ...
• Epitranscriptomics m⁶A analyses reveal distinct m⁶A marks under tumor necrosis factor α (TNF-α)-induced apoptotic conditions in HeLa cells

  Azime Akçaöz-Alasar, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-cleaved-caspase-3 (1:200, 5A1E, Cell Signaling Technology, MA, USA), in PBS/0.1% Triton at 4 °C overnight ...
• Patient-derived tumor organoids from resected non-small cell lung cancers for high-throughput response testing with approved and repurposed drugs

  Kanve N. Suvilesh, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and apoptosis marker cleaved caspase-3 (Rabbit, 9664, 1:100; Cell Signaling Technologies). Percentages of Ki67 and or cleaved caspase-3 positive expression in PDTOs were calculated by a pathologist blinded to the study ...
• Age-related STAT3 signaling regulates severity of respiratory syncytial viral infection in human bronchial epithelial cells

  Caiqi Zhao, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-Cleaved Caspase-3 (Asp175) (1:100, Cat# 9661, Cell Signaling Technology), and rabbit anti-SARS-CoV nucleocapsid protein (N ...
• Age-related STAT3 signaling regulates severity of respiratory syncytial viral infection in human bronchial epithelial cells

  Caiqi Zhao, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-Cleaved Caspase-3 (Asp175) (1:100, Cat# 9661, Cell Signaling Technology), rabbit anti-phospho-RIP (Ser166 ...
• Age-related STAT3 signaling regulates severity of respiratory syncytial viral infection in human bronchial epithelial cells

  Caiqi Zhao, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-Cleaved Caspase-3 (Asp175) (1:1000, Cat#9661S, Cell Signaling Technology), and mouse anti-β-actin (1:2000 ...
• AUTS2, a causative gene for microcephaly, regulates division of intermediate progenitor cells and production of upper-layer neurons

  Kazumi Shimaoka, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-cleaved caspase-3 (1:400; 9661S; Cell Signaling Technology, Danvers, MA), rabbit anti-PAX6 (1:500 ...
• MEK1/2 and ERK1/2 mediated lung endothelial injury and altered hemostasis promote diffuse alveolar hemorrhage in murine lupus

  Haoyang Zhuang, et al., bioRxiv - Immunology 2024

  Quote: ... Primary antibodies anti-cleaved caspase-3 (1:100 Cell Signaling Technology, Danvers, MA), anti-CD31/Pecam1 (R&D Systems 1:200 ...
• Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival

  Jongkyun Kang, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-cleaved caspases-3 (1:150, 9661, Cell Signaling Technology, RRID: AB_2341188), or rabbit anti-Iba1 (1:500 ...
• Investigation of fascin1, a marker of mature dendritic cells, reveals a New role for IL-6 signaling in chemotaxis

  Fumio Matsumura, et al., bioRxiv - Immunology 2020

  Quote: ... the supernatants were used for Western blotting with antibodies against phospho ERK1/2 and total ERK1/2 (Cell Signaling Technology).
• Phosphatases of regenerating liver balance F-actin rearrangements during T cell activation through WD repeat containing protein 1

  Óscar Aguilar-Sopeña, et al., bioRxiv - Immunology 2023

  Quote: ... α-phospho-p44/p42 MAPK (ERK1/2) and α-total p44/p42 MAPK (ERK1/2) were from Cell Signaling (USA).
• An integrated mechanistic and data-driven computational model predicts cell responses to high- and low-affinity EGFR ligands

  Paul J. Myers, Sung Hyun Lee, Matthew J. Lazzara, bioRxiv - Systems Biology 2023

  Quote: siRNAs against ERK1/2 (#6560) and AKT1/2 (#6211) and SignalSilence control siRNA (#6568) were purchased from Cell Signaling Technology and were used at 10 µM ...
• PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity

  Florian Wiede, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (Cell Signaling Technology Cat# 9102, RRID:AB_330744), and p-(Y694 ...
• BRAF inhibitors reprogram cancer-associated fibroblasts to drive matrix remodeling and therapeutic escape in melanoma

  Tianyi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (Cell Signaling Technology, 9107, 1:2000), p-ERK1/2 (Cell Signaling Technology ...
• Selective dephosphorylation by PP2A-B55 directs the meiosis I - meiosis II transition in oocytes

  S. Zachary Swartz, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti phospho ERK1/2 T202/Y204 (Cell Signaling #9101 ...
• Palmitic acid induces inflammation in placental trophoblasts and impairs their migration toward smooth muscle cells through plasminogen activator inhibitor-1

  Amanda M. Rampersaud, et al., bioRxiv - Developmental Biology 2020

  Quote: ... ERK1/2 (9102, 1:1000, Cell Signaling Technology), phosphorylated ERK1/2 (E10 ...
• Signaling modality within gp130 receptor enhances tissue regeneration

  Ruzanna Shkhyan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... p-ERK 1/2 (cat #9106, Cell Signaling), p-Y416-SRC (cat #1246F ...
• Satellite cell depletion in early adulthood attenuates muscular dystrophy pathogenesis

  Justin G. Boyer, et al., bioRxiv - Molecular Biology 2019

  Quote: ... phosphorylated Erk1/2 (1:1000, Cell Signaling Technology), Erk1/2 (1:2000 ...