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1251 - 1300 of 2267 citations for 5 Bromo 2 Tert Butyldimethylsilyl 4 Methylthiazole since 2020

• In Vitro Validation of Computationally Predicted Oncogenic Driver Mutations in EGFR Tyrosine Kinase Domain

  Vidya P Warrier, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho-ERK1/2 and the appropriate secondary antibodies were purchased from Cell Signaling or Santa Cruz Biotechnology ...
• The role of calcium, Akt and ERK signaling in cadmium-induced hair cell death

  Jennifer Galdieri, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (Cell Signaling, 4370) diluted at 1:200.
• Infection-induced epilepsy is caused by increased expression of chondroitin sulfate proteoglycans in hippocampus and amygdala

  Dipan C. Patel, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit polyclonal anti-α-tubulin antibody (2 µg/ml; 2144, Cell Signaling Technology) overnight at 4 °C ...
• Tumor suppressor let-7 acts as a key regulator for maintaining pluripotency gene expression in Muse cells

  Gen Li, Shohei Wakao, Masaaki Kitada, Mari Dezawa, bioRxiv - Cell Biology 2023

  Quote: ... Phospho-p44/p42 MEK/ERK (ERK1/2; Thr202/Tyr 204) (1:1000, Cell Signaling), p44/p42 MEK/ERK (ERK1/2 ...
• Identification of SIRT4 as a novel paralog-specific interactor and candidate suppressor of C-RAF kinase in MAPK signaling

  Mehrnaz Mehrabipour, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-p-ERK(1/2) (1:1000; #4370, Cell Signaling, Frankfurt am Main, Germany); anti-KRAS (1:1000 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (4695, 1:30, Cell Signaling Technology), anti-Hrs (sc-271455 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (4695, 1:1000, Cell Signaling Technology), Phospho-p44/42 MAPK (Erk1/2 ...
• Engineering Regionally-Activated Drugs for Neuroscience

  Zhimin Huang, et al., bioRxiv - Bioengineering 2023

  Quote: ... (2) incubate with primary rabbit anti-c-Fos (1:2000, 2250S, Cell Signaling Technology) and chicken antityrosine hydroxylase (1:2000 ...
• Engineering Regionally-Activated Drugs for Neuroscience

  Zhimin Huang, et al., bioRxiv - Bioengineering 2023

  Quote: ... (2) incubate with primary rabbit anti-c-Fos (1:2000, 2250S, Cell Signaling Technology) antibody in PBS with 0.3% Triton-X for 2h at room temperature ...
• E-cadherin-dependent phosphorylation of EGFR governs a homeostatic feedback loop controlling intercellular junction viscosity and collective migration modes

  Chaoyu Fu, et al., bioRxiv - Cell Biology 2023

  Quote: ... Phospho-Myosin Light Chain 2 (Ser19) antibody (3671, Cell Signaling Technologies, diluted 1:50) according to the manufacturer’s instructions ...
• Oseltamivir (Tamiflu), a Commonly Prescribed Antiviral Drug, Mitigates Hearing Loss in Mice

  Emma Sailor-Longsworth, et al., bioRxiv - Neuroscience 2024

  Quote: ... or antibody anti-pERK1/2 (Thr202/Tyr204, 1:400 dilution, 9101, Cell Signaling Technology) and imaged with a confocal microscope (LSM 700 ...
• Therapeutic expression of RAS Degrader RRSP in Pancreatic Cancer via Nanocarrier-mediated mRNA delivery

  Taylor E. Escher, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Anti–Phospho-p44/42 MAPK (pERK1/2; Cell Signaling Technology, catalog no. 4377, RRID:AB_331775), anti-p44/42 MAPK (ERK1/2 ...
• Synthesis of ionizable lipopolymers using split-Ugi reaction for pulmonary delivery of various size RNAs and gene editing

  K. Yu. Vlasova, et al., bioRxiv - Bioengineering 2024

  Quote: ... cycle 2 Rabbit E-Cadherin (Cell Signaling, 24E10 #3195, dilution 1:200, 1 h), cycle 3 Rabbit CD31 (Abcam ...
• Netrin signaling mediates survival of dormant epithelial ovarian cancer cells

  Pirunthan Perampalam, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK(Erk1/2) T202/Y204 (Cell Signaling Technology; rabbit antibody #4370), p38 MAPK (Cell Signaling Technology ...
• Dormancy-inducing 3D-engineered matrix uncovers mechanosensitive and drug protective FHL2-p21 signaling axis

  Sadra Bakhshandeh, et al., bioRxiv - Bioengineering 2024

  Quote: ... and anti-phospho-p44/42 MAPK (p-ERK1/2) (1:200, #9101S, Cell Signaling). The secondary antibodies are ...
• Vascular endothelial growth factor-D improves lung vascular integrity during acute lung injury

  Yifan Yuan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and Thr18/Ser19 Phospho-Myosin Light Chain 2 (#3674) from Cell Signaling Technology (Danvers); ICAM-1 (Santa Cruz Biotechnologies ...
• Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model

  Christopher D. Balak, et al., bioRxiv - Neuroscience 2024

  Quote: ... 2 μg each of two TFEB antibodies (Abcam ab2636, Cell Signaling CST 37785 (D2O7D), or 2 μg each of two TFE3 antibodies (Abcam ab93808 ...
• A spreading, multi-tissue wound signal initiates whole-body regeneration

  Catriona Breen, Mansi Srivastava, bioRxiv - Developmental Biology 2024

  Quote: ... Primary antibodies used are as follows: rabbit anti-pERK1/2 (Cell Signaling Technology 4370) 1:100 ...
• Transient proliferation by reversible YAP and mitogen-control of the cyclin D1/p27 ratio

  Katherine R. Ferrick, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit phospho-MAPK1/2(Thr202/Tyr204)(1:400, Cell Signaling Technology Cat#4370, RRID:AB_2315112), mouse phospho-S6(235/236)(1:800 ...
• Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation

  Yuma Cho, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-phosoho-Myosin Light Chain 2 (Thr18/Thr19) mAb (95777; Cell Signaling Technology); rabbit anti-TROP2 mAb (ab214488 ...
• PCDHGC3 silencing promotes clear cell renal cell carcinoma metastasis via mTOR/HIF2α and lipid metabolism reprogramming

  Lucía Celada, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (#9101 Cell Signaling Technology) at 1:1,000 dilution ...
• Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state

  Mary C. Rominger, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) 1:1000 (Thr202/Tyr204) (Cell Signaling Technology, 4370), AKT 1:1000 (Cell Signaling Technology ...
• Loss of the predicted cell adhesion molecule MPZL3 promotes EMT and chemoresistance in ovarian cancer

  Ya-Yun Cheng, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and incubated with blocking buffer containing 2% goat serum/PBS (Cell Signaling Technology, 5425) for 30 mins at room temperature ...
• Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex

  Zhe Ji, et al., bioRxiv - Cell Biology 2024

  Quote: ... cells were incubated with 2 ng/mL TGF-β3 (Cell signaling #8425 and #10858) or 20 ng/mL BMP-4 (Peprotech 120-05 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: p44/42 MAPK (Erk1/2) (3A7) Mouse mAb (Cell Signaling Technology, cat. no. 9107)
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: Phospho-MEK1/2 (Ser217/221) (41G9) Rabbit mAb (Cell Signaling Technology, cat. no. 9154) c-Raf (D4B3J ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... /Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... /Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology), Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) were diluted in Intercept PBS Block Buffer (LicorBio ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• X-Linked Histone H3K27 Demethylase Kdm6a Regulates Sexually Dimorphic Differentiation of Hypothalamic Neurons

  Lucas E. Cabrera Zapata, et al., bioRxiv - Neuroscience 2021

  Quote: ... and then incubated overnight at 4 °C with 1:1000 anti-H3K27me3 primary antibody (Cell Signaling Technology, USA). After that ...
• In vivo repair of a protein underlying a neurological disorder by programmable RNA editing

  John R Sinnamon, et al., bioRxiv - Neuroscience 2020

  Quote: ... Sections were incubated overnight at 4°C with rabbit anti-MeCP2 (rabbit mab D4F3, Cell Signaling, 1:500) and rat anti-HA (rat mab 3F10 ...
• Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity

  P-L. Bernard, et al., bioRxiv - Immunology 2021

  Quote: ... Blots were incubated overnight at 4 °C with the corresponding primary antibody directed CISH (Cell Signaling Technology #8731) or Akt (Cell Signaling Technology #9272 ...
• Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells

  Xiaolong Wei, et al., bioRxiv - Cancer Biology 2020

  Quote: ... the membranes were then probed at 4°C overnight with various primary antibodies: anti-γ-H2AX (Cell Signaling), anti-phospho-Chk1 (Ser345 ...
• Sex-Specific Role of Myostatin Signaling in Neonatal Muscle Growth, Denervation Atrophy, and Neuromuscular Contractures

  Marianne E Emmert, et al., bioRxiv - Developmental Biology 2022

  Quote: ... and incubated overnight at 4°C with an antibody against phosphorylated Akt (Ser473) (1:750; Cell Signaling #9271), total Akt (1:750 ...
• A nuclear receptor facilitates differentiation of human PSCs into more mature hepatocytes

  Haiting Ma, et al., bioRxiv - Developmental Biology 2022

  Quote: ... followed by overnight incubation with primary antibody overnight at 4 °C (1:100 rabbit-anti-HNF4A Cell signaling 3113S ...
• Small Extracellular Vesicles Secreted by Region-specific Astrocytes Ameliorate the Mitochondrial Function in a Cellular Model of Parkinson’s Disease

  Loredana Leggio, et al., bioRxiv - Neuroscience 2021

  Quote: ... Coverslips were fixed with 4% PFA and stained with rabbit polyclonal anti-cleaved caspase-3 (Cell Signaling, 9664) primary antibody and with mouse monoclonal anti-map2 primary antibody (Merck Millipore ...
• Sphingosine 1-Phosphate Mediates Adiponectin Receptor Signaling Essential For Lipid Homeostasis And Embryogenesis

  Mario Ruiz, et al., bioRxiv - Cell Biology 2022

  Quote: ... Blots were incubated with primary antibodies overnight at 4°C: rabbit monoclonal anti-HA antibody (C29F4, Cell signaling) 1:5000 dilution ...
• Exogenous and endogenous HDAC inhibitor effects in Rubinstein-Taybi syndrome models

  Elisabetta Di Fede, et al., bioRxiv - Genetics 2020

  Quote: ... Slides were first incubated overnight at 4°C with the anti-Ki67 antibody (#9129 Cell Signaling, 1:400), washed with PBT and then incubated with Alexa-488 anti-Rabbit secondary antibody (#6441-30 SouthernBiotech ...
• Differential cellular responses to adhesive interactions with galectin-8 and fibronectin coated substrates

  Wenhong Li, et al., bioRxiv - Cell Biology 2020

  Quote: ... before incubation at 4 C overnight with appropriate primary antibodies: Rho Rabbit Antibody (Cell Signaling, catalogue no. 8820), Rac1 Mouse Antibody (Cell Signaling ...
• Genetic and Epigenetic Regulation of Skeletal Muscle Ribosome Biogenesis with Exercise

  Vandré C. Figueiredo, et al., bioRxiv - Cell Biology 2020

  Quote: ... membranes were incubated overnight at 4°C with a primary antibody (all Cell Signaling Technology, Inc., Danvers, MA) in blocking solution ...
• Cooperation between oncogenic Ras and p53 stimulates JAK/STAT non-cell autonomously to promote Ras tumor radioresistance

  Yong-Li Dong, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Membranes were probed overnight at 4 °C with anti-pSTAT-3 (Tyr 705) (1:1000, Cell Signaling #9145) or anti-STAT (1:1000 ...
• Enhanced epithelial to mesenchymal transition and chemoresistance in advanced Retinoblastoma tumors is driven by miR-181a

  Vishnu Suresh Babu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... tissues were incubated overnight at 4°C with antibodies for ZEB1 (1:1000; cat#70512, Cell Signaling Technology), Cathepsin L (1:500 ...
• CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer

  Julia M. Houthuijzen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Incubation with primary antibodies was done overnight at 4°C using the following dilutions: PDGFRβ (Cell signaling, #3196) 1:50 ...
• KMT2D Regulates thymic Egress by Modulating Maturation and integrin Expression

  Sarah J Potter, et al., bioRxiv - Immunology 2022

  Quote: ... 167 mM NaCl) were precipitated overnight at 4°C with H3K4me3 antibody (#9727; Cell signaling technology, Danvers, USA) or normal rabbit IgG (considered “input,” # 2729 ...
• The Gene Knockout of Angiotensin II Type 1a Receptor Improves High-fat Diet-Induced Obesity in rat via Promoting Adipose Lipolysis

  Aiyun Li, et al., bioRxiv - Physiology 2022

  Quote: ... and then incubated overnight at 4°C with specific primary antibodies as follows: ATGL (2138S, Cell Signaling Technology), P-HSL (ser660 ...
• Apolipoprotein-based regulation of ganglioside metabolism upon secretase activity inhibition in iPSC-derived cerebral organoids

  Durga Jha, et al., bioRxiv - Neuroscience 2023

  Quote: ... The sections were then incubated overnight at 4°C with an Anti-APP primary antibody (D54D2, Cell Signaling), diluted in the blocking solution ...
• Female specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and Estrogen Receptor α

  Gemma Molinaro, et al., bioRxiv - Neuroscience 2024

  Quote: ... slices were incubated again with a rabbit antibody raised against PTEN over-night at 4°C (Cell Signaling). After washing ...