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1251 - 1300 of 10000+ citations for 1 3 Bis 2 4 hydroxyphenyl 2 propyl benzene since 2020

• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: Phospho-MEK1/2 (Ser217/221) (41G9) Rabbit mAb (Cell Signaling Technology, cat. no. 9154) c-Raf (D4B3J ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... /Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... /Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology), Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) were diluted in Intercept PBS Block Buffer (LicorBio ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mouse mAb (Cell Signaling Technology)/Phospho-p44/42 MAPK (Erk1/2) D13.14.4E XP®Rabbit mAb (Cell Signaling Technology) or Phospho-MEK1/2 (Ser217/221 ...
• Nucleus translocation of tRNA synthetase mediates late integrated stress response

  Na Wei, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit monoclonal ATF-4 (1:1000, Cell Signaling Technology, #11815), rabbit polyclonal SARS (1:1000 ...
• Transferrin-dependent crosstalk between the intestinal tract and commensal microbes contributes for immune tolerance

  Xiaopeng Tang, et al., bioRxiv - Immunology 2020

  Quote: ... anti-phospho-interferon regulatory factor 3 (IRF3) (1:1□000 dilution, 29047S, Cell Signaling Technology, USA), anti-total-IRF3 (1:1□000 dilution ...
• The gamma-Protocadherins regulate the survival of GABAergic interneurons during developmentally-regulated cell death

  Candace H. Carriere, et al., bioRxiv - Neuroscience 2020

  Quote: ... and incubated for 30min in the primary + secondary antibody solution: 2%BSA-PBS + Rabbit anti-mouse Phosopho-Akt (Ser473) antibody (Cell Signaling Technologies 4060; 1:50), Goat anti-Rabbit Alexa 488 secondary antibody (ThermoFisher A32731 ...
• Genetic and chemical inhibition of autophagy in zebrafish induced myeloproliferation

  Kazi Md Mahmudul Hasan, et al., bioRxiv - Cell Biology 2021

  Quote: ... 2% normal goat serum and 0.2% Triton-X100 in PBS) for 30 minutes and hybridized with polyclonal rabbit anti-phospho-Histone H3 (Ser10) antibody (Cell Signaling Technology, #9701; 1:1000) at overnight at 4°C ...
• Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons

  Nicholas L. Truex, et al., bioRxiv - Immunology 2023

  Quote: ... Primary antibodies were incubated for 2 h in a solution of TBST (0.05%) and LI-COR blocking buffer (5%) containing the following antibodies: anti-ERK1/2 (Cell Signaling Technologies; dilution factor: 1/2000) and streptavidin IRdye680 (LI-COR Biosciences ...
• Signaling mechanisms and agricultural applications of (Z)-3-Hexenyl Butyrate-mediated stomatal closure

  Celia Payá, et al., bioRxiv - Molecular Biology 2023

  Quote: ... The resulting supernatants (10 μL) were analyzed by Western Blot with Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling, 1679101S; dilution 1:1,000) primary antibodies ...
• Single-cell transcriptomic analysis unveils spinal motor neuron subtype diversity underpinning the water-to-land transition in vertebrates

  Ee Shan Liau, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-cleaved caspase-3 (1:500 Cell Signaling Cat# 9661, RRID:AB_2341188). Guinea pig anti-Foxp1 (1:320000) ...
• Revisiting the origin of interleukin 1 (IL-1) based on biological activities of IL-1 in anamniotes and their sub-functionalization in amniotes

  Eva Hasel de Carvalho, et al., bioRxiv - Immunology 2022

  Quote: ... or 1:1000 anti-cleaved Caspase-3 #9661 (rabbit, Cell Signaling Technology), followed by 1:3000 goat anti-rabbit HRP 1706515 (BioRad).
• Lipid nanoparticles delivering constitutively active STING mRNA as a novel anti-cancer therapeutic approach

  Wei Liu, et al., bioRxiv - Bioengineering 2022

  Quote: ... and anti-Cleaved Caspase-3 (Asp175) (1:500, 9661, Cell Signaling Technology). The secondary antibodies used were Alexa Fluor 594 goat anti-mouse IgG (1:500 ...
• Transcriptional and Cytotoxic Responses of Human Intestinal Organoids to Interferon Types I, II, and III

  David A. Constant, et al., bioRxiv - Immunology 2021

  Quote: ... stained with anti-cleaved caspase 3 (Cell Signaling Technology #9661S; 1:400), anti-E-cadherin (Becton Dickinson #610182 ...
• Multiplexed drug testing of tumor slices using a microfluidic platform

  L. F. Horowitz, et al., bioRxiv - Bioengineering 2020

  Quote: ... rabbit anti-active caspase 3 (Asp175) (1/600, Cell Signaling, Antibody #9661), mouse anti-HuNu (1/500 ...
• GCNA is a histone binding protein required for spermatogonial stem cell maintenance

  Jonathan Ribeiro, Gerry P. Crossan, bioRxiv - Physiology 2022

  Quote: ... anti-Cleaved Caspase 3 (1:300, catalog no. 9661, Cell Signaling Technology); anti-DNMT3B (1:250 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and Cleaved Caspase 3 (1:100, Cat#: 9661, Cell Signaling, Danvers, MA) overnight at 4°C ...
• Flexible Simultaneous Mesoscale Two-Photon Imaging Of Neural Activity at High Speeds

  Mitchell Clough, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-cleaved caspase-3 (Asp175) (9661; Cell Signaling; 1:250 dilution), and mouse anti-HSP70/HSP72 (C92F3A-5 ...
• RNA-binding protein Orb2 causes microcephaly and supports centrosome asymmetry in Drosophila neural stem cells

  Beverly V. Robinson, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-cleaved Caspase 3 (CC3, 1:75; Cell Signaling Technology, 9661s), mouse anti-Pros (clone MR1A ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-cleaved caspase 3 (CC3) (rabbit, 1:250) (#9664, Cell Signaling Technology), anti-FUNDC1 (rabbit ...
• Transcriptional Profiling Reveals the Transcription Factor Networks Regulating the Survival of Striatal Neurons

  Lin Yang, et al., bioRxiv - Neuroscience 2021

  Quote: ... Primary antibodies against cleaved Caspase-3 (1:500; Cell Signaling, 9661, 43) were diluted in 10% donkey serum block solution ...
• The Cardiolipin Transacylase Tafazzin Regulates Basal Insulin Secretion and Mitochondrial Function in Pancreatic Islets from Mice

  Laura K. Cole, et al., bioRxiv - Physiology 2021

  Quote: ... rabbit activated caspase 3 (1:200) (Cell Signaling Technologies, Danvers MA, USA) overnight at 4°C ...
• Human iPSC-Derived Cardiomyocytes are Susceptible to SARS-CoV-2 Infection

  Arun Sharma, et al., bioRxiv - Cell Biology 2020

  Quote: ... cleaved caspase-3 (1:200, Cell Signaling Technology Cat# 9661, RRID: AB_2341188). Samples were then rinsed 5 times for 2 minutes each with PBS containing 0.3% Triton X-100 ...
• Neonatal enthesis healing involves non-inflammatory formation of acellular scar through ECM secretion by resident cells

  Ron Carmel Vinestock, et al., bioRxiv - Molecular Biology 2021

  Quote: ... rabbit anti-cleaved caspase-3 (Asp175) antibody (1:200, #9664s, Cell Signaling) or rat anti-F4/80 antibody (1:50 ...
• Eukaryotic translation initiation factor eIF4E-5 is required for spermiogenesis in Drosophila melanogaster

  Lisa Shao, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-caspase-3 (1:400; Asp175, Cell Signaling Technology, Danvers, USA), guinea pig anti-Soti (1:100 ...
• Deficiency in Lyst function leads to accumulation of secreted proteases and predisposition to mechanic stress-induced retinal detachment

  Xiaojie Ji, et al., bioRxiv - Genetics 2021

  Quote: ... glyceraldehyde 3-phosphate dehydrogenase (GAPDH, Cell Signaling, 2118, rabbit monoclonal, 1:1000), phospho-ERM (Cell Signaling ...
• The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

  Ke Xu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-Caspase-3 antibody (1:1,000 dilution, 9662, Cell Signaling Technology), rabbit anti-Cleaved Caspase-3 monoclonal antibody (1:1,000 dilution ...
• Talin regulates steady-state tensional homeostasis to drive vascular morphodynamics and cancer

  Pinelopi Nikolopoulou, et al., bioRxiv - Cell Biology 2022

  Quote: ... Cleaved Caspase-3 (1:300 dilution, Rabbit monoclonal; Cell Signaling, Cat# 9664), PECAM (1:400 dilution ...
• Talin regulates steady-state tensional homeostasis to drive vascular morphodynamics and cancer

  Pinelopi Nikolopoulou, et al., bioRxiv - Cell Biology 2022

  Quote: ... cleaved Caspase-3 (1:100 dilution, Rabbit monoclonal; Cell Signaling, Cat# 9664), YAP (1:100 dilution ...
• Functional characterization of cardiac fibroblasts in response to hemodynamic alteration

  Manabu Shiraishi, Ken Suzuki, Atsushi Yamaguchi, bioRxiv - Molecular Biology 2022

  Quote: ... anti-cleaved caspase 3 Ab at 1:100 dilution (9661, Cell Signaling), anti-αSMA Ab at 1:00 dilution (ab5694 ...
• Soluble VE-cadherin disrupts endothelial barrier function via VE-PTP/RhoA signalling

  Juna-Lisa Knop, et al., bioRxiv - Physiology 2022

  Quote: ... cleaved caspase-3 (Asp175) antibody (WB 1:600, Cell Signaling, CatNo 9661), caspase antibody (WB 1:1000 ...
• An adapted stem cell-derived microglia protocol for the study of microgliopathies and other neurological disorders

  Marie-France Dorion, et al., bioRxiv - Neuroscience 2023

  Quote: ... NLR family pyrin domain containing 3 (NLRP3; 1:500; #15101S, Cell Signaling) and GAPDH (1:5000 ...
• Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury

  Mary E. Mohr, et al., bioRxiv - Cell Biology 2023

  Quote: ... Primary antibodies used include: cleaved Caspase 3 (1:200, Cell Signaling, 9664), pMLKL (1:100 ...
• Neuroprotective effects of hepatoma-derived growth factor in models of Huntington’s disease

  Kerstin Voelkl, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit anti-cleaved Caspase-3 (Cell Signaling Technology, 9661, 1:500). Cells were washed for 5 min in PBS and incubated for 30 min in the dark with Alexa Fluor 488 ...
• Genetically perturbed myelin as a risk factor for neuroinflammation-driven axon degeneration

  Janos Groh, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-cleaved caspase 3 (1:300, catalog no. 9664; Cell Signaling); rabbit anti-pMLC Thr18/Ser19 (1:100 ...
• Role of the NO-GC/cGMP signaling pathway in platelet biomechanics

  Johanna G. Rodríguez, et al., bioRxiv - Biochemistry 2023

  Quote: ... glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (rabbit, 1:1000, 14C10, Cell Signaling #2118S), NO-GC (sGC β1 ...
• RhoB promotes Salmonella survival by regulating autophagy

  Marco Kirchenwitz, et al., bioRxiv - Cell Biology 2023

  Quote: ... cleaved-caspase-3 (9661, 1:1000 dilution, RRID: AB_2341188, Cell Signaling Technology), AKT (9272 ...
• Primordial germ cell DNA demethylation and development require DNA translesion synthesis

  Pranay Shah, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-cleaved caspase 3 (1:400, catalog no. 9661; Cell Signaling Technology); anti-MVH (ab27591) ...
• Cancer tissue of origin constrains the growth and metabolism of metastases

  Sharanya Sivanand, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or Cleaved Caspase 3 (Asp 175) (1:400 dilution; Cell Signaling 9661). Antibodies were diluted in 10% normal goat serum diluted 1:2 (Thermo Fischer ...
• MicroRNAs are necessary for the emergence of Purkinje cell identity

  Norjin Zolboot, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit anti-cleaved caspase-3 (1:500, Cell Signaling Technology, 9661). Secondary antibodies used were donkey anti-mouse-AF594 (Invitrogen ...
• Over supplementation of folic acid reduces survival 24 hours after hypoxia in male and female Drosophila melanogaster

  Siddarth Gunnala, et al., bioRxiv - Neuroscience 2024

  Quote: ... The active caspase-3 primary antibody (ac3; 1:100, Cell Signaling Technologies, Danvers ...
• Surface-associated antigen induces B-cell permeabilization and lysosome exocytosis facilitating antigen uptake and presentation to T-cells

  Fernando Y. Maeda, et al., bioRxiv - Cell Biology 2021

  Quote: ... and incubated with rabbit anti-phosphorylated myosin light chain 2 (pMLC2) antibodies (Cell Signaling Technology) to label activated NMII (Bresnick 1999) ...
• Novel ERR pan-agonists ameliorate heart failure through boosting cardiac fatty acid metabolism and mitochondrial function

  Weiyi Xu, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... Primary antibodies used are listed as below: anti-phosph-ERK1/2 (Cell Signaling Technologies, 9101S), anti-ERK1/2 (Cell Signaling Technologies ...
• Semaphorin3F Drives Dendritic Spine Pruning through Rho-GTPase Signaling

  Bryce W. Duncan, et al., bioRxiv - Neuroscience 2021

  Quote: ... For Cofilin we used rabbit monoclonal anti-Cofilin1/2 antibodies (Cell Signaling Technology# 5175, RRID:AB_10622000), and rabbit monoclonal anti-phospho-Cofilin Ser3 (Cell Signaling Technology# 3313 ...
• Loss of O-GlcNAcylation on MeCP2 Thr 203 Leads to Neurodevelopmental Disorders

  Juanxian Cheng, et al., bioRxiv - Neuroscience 2020

  Quote: ... and the rest was incubated with 2 μg anti-HA antibody (Cell Signaling Technology, 3724) or anti-GFP (Cell Signaling Technology ...
• Schizophrenia Risk Proteins ZNF804A and NT5C2 Interact at Synapses

  Afra Aabdien, et al., bioRxiv - Neuroscience 2021

  Quote: ... in PBS and blocked simultaneously in 2% normal goat serum (NGS – Cell Signaling Technology, 5425) in PBS for one hour with agitation ...
• MG132 induces progerin clearance and improves disease phenotypes in fibroblasts of patients affected with Hutchinson-Gilford Progeria-like syndromes

  Karim Harhouri, et al., bioRxiv - Genetics 2021

  Quote: ... 2/ Colorimetric detection of senescence-associated β galactosidase following the manufacturer’s protocol (Cell Signaling #9860). Cells were seeded in 4 chamber-wells slides (SPL Lifesciences ...