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1101 - 1150 of 10000+ citations for Acetamide N 2 3 dihydro 2 3 hydroxy 2 quinolinyl 1 3 dioxo 1H inden 5 yl since 2020

• Antihypertensive effect of brain-targeted mechanical intervention with passive head motion

  Shuhei Murase, et al., bioRxiv - Bioengineering 2022

  Quote: ... rabbit polyclonal anti-cleaved caspase- 3 (9661; Cell Signaling Technology, Danvers, MA) at 1:1,000 ...
• Polo-like kinase-1 Inhibitors and the Antiandrogen Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling

  Jesse C. Patterson, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Sections were stained with cleaved caspase-3 antibody (Cell Signaling Technologies, 9664) followed by detection with horseradish peroxidase conjugated secondary antibody and diaminobenzidine with hematoxylin used as a counterstain ...
• Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis

  Sai Zhang, et al., bioRxiv - Genomics 2020

  Quote: ... The following antibodies were used: H3K4me1 (#5326S, lot 3, Cell Signaling Technologies), H3K4me3 (#9751S ...
• PTBP1/HNRNP I controls intestinal epithelial cell regeneration by maintaining stem cell survival and stemness

  Wesley S. Tung, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Primary antibodies used are rabbit anti-active CASPASE 3 (Cell Signaling, 9661), mouse anti-KI67 (BD Pharmingen ...
• Combination EZH2 inhibition and retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells

  Eleanor O’Brien, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Primary antibodies used were: Cleaved Caspase-3 (9661; Cell Signaling Technology (CST)) ...
• FLECS Technology for High-Throughput Screening of Hypercontractile Cellular Phenotypes in Fibrosis: A Function-First Approach to Anti-Fibrotic Drug Discovery

  Yao Wang, et al., bioRxiv - Bioengineering 2023

  Quote: ... cells were incubated with rabbit anti-Smad2/3 antibody (Cell Signaling Technology, Cat #8685 ...
• Zoledronic acid improves bone quality and muscle function in a high bone turnover state

  Trupti Trivedi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Sections were incubated with phospho-SMAD2/3 (Cell Signaling Technology, Danvers, MA) at a 1:500 dilution overnight at 4°C ...
• Fibroblast activation protein regulates natural killer cell migration, extravasation and tumor infiltration

  Allison A. Fitzgerald, et al., bioRxiv - Immunology 2023

  Quote: ... clusters were stained using anti-cleaved caspase-3 (Cell Signaling, cat#9661). Hoechst 33342 ...
• Sulfatase 2 Inhibition Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy Through Augmentation of Extracellular ATP

  Jasmine M Manouchehri, et al., bioRxiv - Cancer Biology 2023

  Quote: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (Cell Signaling Technology, Cat #3683, RRID: AB_1642205) was used as a loading control ...
• Water-soluble 4-(dimethylaminomethyl)heliomycin exerts greater antitumor effects than parental heliomycin by targeting the tNOX-SIRT1 axis and apoptosis in oral cancer cells

  Atikul Islam, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-cleaved caspase-3 antibodies were purchased from Cell Signaling Technology, Inc ...
• Paclitaxel-loaded Cationic Fluid Lipid Nanodiscs and Liposomes with Brush-Conformation PEG Chains Penetrate Breast Tumors and Trigger Caspase-3 Activation

  Lorena Simón-Gracia, et al., bioRxiv - Biophysics 2022

  Quote: ... and rabbit anti-cleaved Caspase-3 (cat. no. 9661, Cell Signaling Technology) as primary antibodies in blocking buffer diluted 1 in 5 in PBST (antibody dilution 1/200 and 1/400 ...
• Blocking necroptosis reduces inflammation and tumor incidence in a mouse model of diet-induced hepatocellular carcinoma

  Sabira Mohammed, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and Caspase-3 (Cat. No. 9662) from Cell Signaling Technology (Danvers, MA); p62 (Cat ...
• IRE1 RNase controls CD95-mediated cell death

  D Pelizzari-Raymundo, et al., bioRxiv - Cell Biology 2022

  Quote: ... Caspase-8 (Adipogen, AG-20B-0057-C100, Caspase-3 (Cell signaling, 14220), Cleaved caspase-3 (Cell signaling ...
• Antagonistic nanobodies reveal mechanism of GSDMD pore formation and unexpected therapeutic potential

  Lisa D.J. Schiffelers, et al., bioRxiv - Immunology 2023

  Quote: ... rabbit anti-caspase-3 clone D3R6Y (Cell Signaling Technology Cat#14220, RRID:AB_2798429), rabbit anti-cleaved caspase-3 (Asp175 ...
• Elraglusib induces cytotoxicity via microtubule destabilisation independently of GSK3 inhibition

  Josh T. Coats, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Flow cytometry antibody: rabbit anti-phospho-histone 3 (Ser10) (Cell Signaling 3465) used at 1:100 ...
• Systemic low-dose anti-fibrotic treatment attenuates ovarian aging in the mouse

  Farners Amargant, et al., bioRxiv - Developmental Biology 2024

  Quote: For Cleaved Caspase 3 (CC3; 9579S, Cell Signaling Technology, Danvers, MA, US) detection ...
• Promoting Polarization and Differentiation of Primary Human Salivary Gland Stem/Progenitor Cells in Protease-Degradable Hydrogels via ROCK Inhibition

  Apoorva S. Metkari, et al., bioRxiv - Bioengineering 2024

  Quote: ... both with 3% (w/v) bovine serum albumin (BSA, Cell Signaling Technology), for 16 h at room temperature ...
• Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice

  Sreeram Vallabhaneni, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-phospho-ERK1/2 (Cell Signaling, CST4370), and anti–β-actin (Sigma) ...
• Inositol depletion regulates phospholipid metabolism and activates stress signaling in HEK293T cells

  Mahmoud Suliman, et al., bioRxiv - Cell Biology 2022

  Quote: ... P44/42 Erk1/2 (#9102, Cell signaling), Phospho-p44/42 MAPK (Erk1/2 ...
• DOK1 and DOK2 regulate CD8⁺ T cell signaling and memory formation without affecting tumor cell killing

  V. Laletin, et al., bioRxiv - Immunology 2021

  Quote: ... p-Erk1/2 (Cell Signaling Technology #4377), Erk-1/2 (Cell Signaling Technology #9102 ...
• Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion

  Sina Ibne Noor, et al., bioRxiv - Biochemistry 2020

  Quote: ... Rabbit anti-ERK1/2 (#9102, Cell Signaling), 1:1000 ...
• Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion

  Sina Ibne Noor, et al., bioRxiv - Biochemistry 2020

  Quote: ... Rabbit anti-MEK1/2 (#9122, Cell Signaling), 1:1000 ...
• The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

  Elisa Avolio, et al., bioRxiv - Cell Biology 2021

  Quote: ... Total ERK1/2 (Cell Signaling Technology #4395), 1:1000 ...
• A molecular clock controls periodically driven cell migration in confined spaces

  Sung Hoon Lee, et al., bioRxiv - Systems Biology 2020

  Quote: ... Myosin Light Chain 2 (Cell Signaling, 8505S), mDia1 (Cell Signaling ...
• Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis

  Benjamin Ng, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-p-ERK1/2 (4370, Cell Signaling), anti-ERK1/2s (4695 ...
• Pseudomonas aeruginosa Stimulates Inflammation and Enhances KSHV-Induced Cell Proliferation and Cellular Transformation through Both LPS and Flagellin

  Ashley Markazi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... phospho-ERK1/2 (4370S, Cell Signaling Technology).
• miR-200 deficiency promotes lung cancer metastasis by activating cancer-associated fibroblasts

  Bin Xue, et al., bioRxiv - Cancer Biology 2020

  Quote: ... pErk1/2 pAb (Cell Signaling Technology, 4370), TTF1 (Nkx2.1 ...
• Targeting Chromatin Effector Pygo2 to Enhance Immunotherapy in Prostate Cancer

  Yini Zhu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-Erk1/2 (Cell Signaling Technology, 4370), p53 (Cell Signaling Technology ...
• Novel ERR pan-agonists ameliorate heart failure through boosting cardiac fatty acid metabolism and mitochondrial function

  Weiyi Xu, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... anti-ERK1/2 (Cell Signaling Technologies, 9102S), anti-LC3B (Cell Signaling Technologies ...
• Cross-activation of the FGF, TGF-β and WNT pathways constrains BMP4-mediated induction of the Totipotent state in mouse embryonic stem cells

  Thulaj Meharwade, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-ERK1/2 (137F5) (Cell Signaling 4695S) lot 28 ...
• Human cytomegalovirus UL7, miR-US5-1 and miR-UL112-3p inactivation of FOXO3a protects CD34⁺ hematopoietic progenitor cells from apoptosis

  Meaghan H. Hancock, et al., bioRxiv - Microbiology 2020

  Quote: ... P-ERK1/2 (Thr202/Tyr204, Cell Signaling), PARP (Cell Signaling) ...
• Targeting a broad spectrum of KRAS-mutant cancers by hyperactivation-induced cell death

  Johanna Lilja, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK1/2 (Cat. no. 91025, Cell Signaling), phospho-AKT (Ser473 ...
• Taxane chemotherapy leads to breast cancer dormancy escape by stromal injury mediated IL-6/MAP2K signaling

  Ramya Ganesan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rabbit ERK1/2 IgG (Cell Signaling Technology) (cat ...
• Double-targeted knockdown of miR-21 and CXCR4 inhibits malignant glioma progression by suppression of the PI3K/AKT and Raf/MEK/ERK pathways

  Feijiao Liu, Bo Yang, bioRxiv - Cancer Biology 2020

  Quote: ... and phospho-ERK1/2 (Cell Signaling Technology). The protein levels were digitalized using ImageJ 1.48 version (NIH ...
• The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation

  Leila Revollo, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti Erk1/2(Cell Signaling Technology, #4695), anti P-selectin (R&D Systems ...
• THEMIS is a priming substrate of non-receptor tyrosine phosphatase PTPN6/SHP1 and plays dual roles during T cell development

  Jiali Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-ERK1/2 (Cell Signaling Technology, 4377), anti-phospho-ERK1/2 (Thr202/Tyr204 ...
• Discovery of novel ID2 antagonists from pharmacophore-based virtual screening as potential therapeutics for glioma

  Genshen Zhong, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-MMP-2 (Cell Signaling Technology, #87809), anti-VEGFA (Cell Signaling Technology ...
• Oncogenic metabolic rewiring independent of proliferative control in human mammary epithelial cells

  Wentao Dong, et al., bioRxiv - Biochemistry 2022

  Quote: ... ERK1/2 (Cell Signaling, Cat. No. 9102) phospho-ERK1/2 (Cell Signaling ...
• Cellular protection from H₂O₂ toxicity by Fv-Hsp70. Protection via catalase and gamma-glutamyl cysteine synthase

  Chris Hino, et al., bioRxiv - Cell Biology 2023

  Quote: ... and polyclonal Nrf 2 (Cell Signaling 336495). All antibodies were used at 1:1000 dilution in blocking buffer ...
• Epigenomic Analyses Identify FOXM1 As a Key Regulator of Anti-Tumor Immune Response in Esophageal Adenocarcinoma

  Benjamin Ziman, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 2 μg FOXM1 antibody (Cell Signaling, 20459) was then added and incubated at 4 °C overnight on a rotating platform ...
• Nischarin negatively impacts ShcD-mediated tumor cell migration

  Rayan A. Hago, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-Erk1/2 (cst4695-Cell Signaling, USA), anti-Nischarin (ab204588-Abcam ...
• PML mutants resistant to arsenic induced degradation fail to generate the appropriate SUMO and ubiquitin signals required for RNF4 and p97 recruitment

  Ellis G. Jaffray, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-SUMO- 2 (Cell signaling 4971S), rabbit FK2 ubiquitin (Enzo BML-PW8810-0500) ...
• SHIP2 controls matrix mineralization by regulation of the RhoA/ROCK pathway and remodeling of the actin cytoskeleton

  Anais Fradet, Jamie Fitzgerald, bioRxiv - Cell Biology 2022

  Quote: ... Erk1/2 antibody (Cell Signaling Technologies #9107) 1/2000 ...
• MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer

  Olaf Klingbeil, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p-LATS1/2 (T1079/T1041) (Cell Signaling, D57D3 ...
• Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon

  Daniela Araiza-Olivera, et al., bioRxiv - Cancer Biology 2024

  Quote: ... -total ERK1/2 (Cell Signaling Tech #9102), -GAPDH (#4138).
• Glioma-associated fibroblasts promote glioblastoma resistance to temozolomide through CCL2-CCR2 paracrine signaling

  Mingrong Zuo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... total-ERK1/2 (Cell Signaling Technology #4696), Phospho-p38 MAPK (T180/Y182 ...
• Renal-Derived Human sPRR Does Not Increase Blood Pressure in High Fat Diet Mice

  Gertrude Arthur, et al., bioRxiv - Physiology 2024

  Quote: ... Aquaporin 2 (Cell Signaling Technology Inc, 3487) and GAPDH (Sigma Aldrich ...
• A high-throughput zebrafish screen identifies novel candidate treatments for Kaposiform Lymphangiomatosis (KLA)

  Ivan Bassi, et al., bioRxiv - Developmental Biology 2024

  Quote: ... phosphor-ERK1/2 (#4376, Cell Signaling, USA), and Podoplanin (M3619 ...
• Chitinase 3-like-1 (CHI3L1) Inhibits Innate Anti-Tumor and Tissue Remodeling Immune Responses by Regulating CD47-SIRPα and CD24-Siglec10-Mediated Phagocytosis

  Bing Ma, et al., bioRxiv - Immunology 2024

  Quote: ... and SHP-2 (Cell Signaling Technology, #3752) overnight at 4°C in TBST and 5% BSA ...
• Spatiotemporal Proteomics Deciphers Functional Selectivity of EGFR ligands

  Akihiro Eguchi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-Erk1/2 (#4695; Cell Signaling Technology) mouse anti-phospho-Erk1/2 (T202/T204 ...