Labshake search

51 - 100 of 10000+ citations since 2019

• Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profile

  Audrey Burban, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Notch1 (1:1000, Cell Signaling, #CST3608), Olig2 (1:2000 ...
• Cholesterol biosynthesis inhibition synergizes with AKT inhibitors in triple-negative breast cancer

  Alissandra L. Hillis, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cells were incubated with primary antibody for 1 hour rocking at room temperature (LAMP1; Cell Signaling Technology, 9091, 1:100). Cells were washed three times with 1X PBS and then incubated with secondary antibody for 30 minutes rocking at room temperature (Goat anti-Rabbit IgG Alexa Fluor 488 ...
• RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism

  Leïla Dumas, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Tubulin (1:1000, Cell Signaling CS2146), Lamin A (1:1000 ...
• RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism

  Leïla Dumas, et al., bioRxiv - Cancer Biology 2024

  Quote: ... P(S240-244)-rpS6 (1:1000, Cell signaling 2215S), GRSF1 (1:1000 ...
• Mechanical confinement governs phenotypic plasticity in melanoma

  Miranda V. Hunter, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-acetylated tubulin (Cell Signaling Technologies, CST 5335), rat anti-tyrosinated tubulin (Millipore Sigma ...
• Antibody targeting of surface PSGL-1 glycoprotein leads to lymphoma apoptosis and tumorigenesis inhibition

  João L. Pereira, et al., bioRxiv - Cancer Biology 2024

  Quote: ... tissue sections were incubated with rabbit anti-cleaved caspase 3 (1:200; cat. no. 9661, Cell Signaling Technology) or rabbit anti-Ki67 (1:500 ...
• Mitochondrial uncoupler and retinoic acid synergistically induce differentiation and inhibit proliferation in neuroblastoma

  Haowen Jiang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and incubated with anti-human N-Myc rabbit monoclonal antibody (#51705, Cell Signaling Technology, Inc., MA, USA at a dilution of 1:300) and S100 beta (EP32 ...
• The Notch1/Delta-like-4 axis is crucial for the initiation and progression of oral squamous cell carcinoma

  Christian T. Meisel, et al., bioRxiv - Cancer Biology 2024

  Quote: ... polyclonal rabbit anti-Notch1 (D1E11) (dilution 1:100; 3608S; Cell Signaling), polyclonal rabbit anti-Runx1 (dilution 1:100 ...
• SMARCD1 is a “Goldilocks” metastasis modifier

  Christina Ross, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mouse anti-Myc-tag (1:1000; Cell Signaling). Goat anti-rabbit (Santa Cruz ...
• Ligand supplementation restores the cancer therapy efficacy of an antirheumatic drug auranofin from serum inactivation

  Yuan Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... monoclonal mouse anti-DLAT (1:1,000; catalog no. 12362S; Cell signaling Technology); monoclonal mouse HRP-conjugated GAPDH (1:10,000 ...
• Persister cancer cells are characterized by H4K20me3 heterochromatin that defines a low inflammatory profile

  Valentina Ramponi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mouse anti-Histone H3 (96C10) Antibody (1:500, Cell Signaling, #3638), mouse anti-γ-Tubulin Antibody clone GTU-88 (1:5000 ...
• The long noncoding RNA lnc-FANCI-2 restricts RAS signaling and phosphorylation of Akt and Erk in HPV16-infected cervical cancer cells

  Haibin Liu, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Erk1/2 (p44/42 MAPK, #4695), anti-phospho-Erk1/2 (#4370), and anti-IGFBP3 (D1U9C, #25864) were from Cell Signaling Technology (Danvers, MA). Anti-VIM (#MA5-11883 ...
• The long noncoding RNA lnc-FANCI-2 restricts RAS signaling and phosphorylation of Akt and Erk in HPV16-infected cervical cancer cells

  Haibin Liu, et al., bioRxiv - Cancer Biology 2024

  Quote: ... LY294002 (Cell Signaling Technology, Danvers, MA, #9901) or 10 µM mitogen-activated protein kinase kinase (MEK ...
• Cholesterol biosynthesis inhibition synergizes with AKT inhibitors in triple-negative breast cancer

  Alissandra L. Hillis, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 0.3% Triton X-100 in PBS) and incubated with anti-cleaved caspase-3 (Cell Signaling Technology, 9661) in blocking buffer overnight at 4°C ...
• Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer

  Fei Yue, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Non-phospho (Active) β-Catenin (Ser33/37/Thr41) (D13A1) rabbit antibody (Cell Signaling Technology, 8814), β-Catenin mouse Antibody (BD Biosciences ...
• Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer

  Fei Yue, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Myc-tag (71D10) rabbit antibody (Cell Signaling Technology, 2278), Flag-tag M2 mouse antibody (Sigma-Aldrich ...
• Increased interaction between connexin43 and microtubules is critical for glioblastoma stem-like cell maintenance and tumorigenicity

  James W. Smyth, et al., bioRxiv - Cancer Biology 2024

  Quote: ... or V5 tag (Cell Signaling Technology) were used as isotype controls ...
• Transgenic αβ TCR tonic signaling is leukemogenic while strong stimulation is leukemia-suppressive

  Telmo A. Catarino, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-cleaved-caspase 3 (1:200, 9661, Cell Signaling), Ki67 (1:500 ...
• Increased interaction between connexin43 and microtubules is critical for glioblastoma stem-like cell maintenance and tumorigenicity

  James W. Smyth, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-Notch1 (Cell Signaling Technology), mouse anti-α-tubulin (MilliporeSigma) ...
• DNA damage-induced PARP/ALC1 activation leads to Epithelial-to-Mesenchymal transition stimulating homologous recombination

  Fatemeh Rajabi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... As a positive control α-H3K27me3 rabbit monoclonal antibody (Cell Signaling Technology, # 9733). As a negative control ...
• Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profile

  Audrey Burban, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Cleaved caspase 3 (1:100, Cell signaling, #D175), anti-SOX2 (1:100 ...
• Exploiting a metabolic vulnerability in brain tumour stem cells using a brain-penetrant drug with safe profile

  Audrey Burban, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 20 ng/mL mEGF (Cell Signaling, #5331SC) and 20 ng/mL mFGF (Abbiotec ...
• The expression of PKM1 and PKM2 in developing, benign, and cancerous prostatic tissues

  Lin Li, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and HRP-conjugated secondary antibody (Cell Signaling, Beverly, MA). Protein bands were visualized by using ProSignal® Dura ECL Reagent (Genesee Scientific ...
• HAF Prevents Hepatocyte Apoptosis and Hepatocellular Carcinoma through Transcriptional Regulation of the NF-κB pathway

  Karen Acuña Pilarte, et al., bioRxiv - Cancer Biology 2024

  Quote: ... RIP3 were purchased from Cell Signaling Technology (Danvers, MA), antibodies against pp50 and NEMO were from Santa Cruz Biotechnology (Dallas ...
• Negative regulation of APC/C activation by MAPK-mediated attenuation of Cdc20^Slp1 under stress

  Li Sun, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit polyclonal anti-phospho-p44/42 (detecting activated Pmk1) (Cell Signaling Technology; #9101; 1:1,000); rabbit monoclonal anti-phospho-p38 (Cell Signaling Technology ...
• Negative regulation of APC/C activation by MAPK-mediated attenuation of Cdc20^Slp1 under stress

  Li Sun, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit monoclonal anti-phospho-p38 (Cell Signaling Technology; #4511; 1:1,000); rabbit polyclonal anti-PSTAIRE (detecting Cdc2 ...
• Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer

  Larysa Poluben, et al., bioRxiv - Cancer Biology 2024

  Quote: ... FOXA1 (Cell Signaling Technologies, 53528S), BRD4 (Diagenode ...
• Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer

  Larysa Poluben, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Accel-NGS 2S Plus DNA Libraries Kit with Unique Dual Indexing (Swift Biosciences, 29096/290384) or SimpleChIP ChIP-seq Multiplex Oligos for Illumina with Dual Index Primers (Cell Signaling Technology, 47538) according to the manufacturer’s instructions ...
• Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer

  Larysa Poluben, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-H3 (Cell Signaling Technologies, #4499S, 1:2000). The siRNA for non-targeting control (Dharmacon ...
• Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer

  Larysa Poluben, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p300 (Cell Signaling Technologies, 57625S) and then conjugation to Protein A and G Dynabeads (Thermo Fisher Scientific) ...
• Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2

  Chrystian Junqueira Alves, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cells were lysed using Cell Lysis Buffer (Cell Signaling, 9803). Protein concentrations were determined using a BCA assay (Thermo Scientific) ...
• Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer

  Larysa Poluben, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-PSA (Cell Signaling Technologies , #5365S, 1:2000), anti-H3 (Cell Signaling Technologies ...
• Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer

  Larysa Poluben, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Libraries were generated using the SimpleChIP ChIP-seq Multiplex Oligos for Illumina with Dual Index Primers (Cell Signaling Technology, 47538) according to the manufacturer’s instructions ...
• RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway

  Fang Huang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-NF-κB p65(Cell Signaling Technology, #8242), anti-IκBα (Cell Signaling Technology ...
• Co-Essentiality Analysis Identifies PRR12 as a Regulator of Cohesin and Genome Integrity

  Alexandra L. Nguyen, et al., bioRxiv - Cell Biology 2024

  Quote: The following antibodies were used: Phospho-ATM (Ser1981) (10H11.E12) (1:500, Cell Signaling; 4526), PRR12 (1:250 ...
• BAX and BAK expression triggers multiple IRE1 signaling outputs under ER stress

  Claudia Sepulveda, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-SAPK/JNK (1:1000; 9252 Cell Signaling). Detection of the phosphorylated IRE1α form was performed using the Phostag™ assay loading 15 μg of total protein onto 4% SDS-PAGE minigels containing 80 μM of Phostag™ in the presence of 25 mM MnCl2.
• BAX and BAK expression triggers multiple IRE1 signaling outputs under ER stress

  Claudia Sepulveda, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-IRE1alpha (1:1000; 3294, Cell Signaling), anti-Phospho-SAPK/JNK (1:1000 ...
• RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway

  Fang Huang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Phospho-stat1 (Tyr701) (Cell Signaling Technology, #8062),and anti-MFGE8(R&D systems ...
• RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway

  Fang Huang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Phospho-Akt (Ser473) (Cell Signaling Technology, #4060), anti-Akt (pan ...
• RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway

  Fang Huang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Phospho-NF-κB p65 (Cell Signaling Technology, #3033), anti-NF-κB p65(Cell Signaling Technology ...
• BAX and BAK expression triggers multiple IRE1 signaling outputs under ER stress

  Claudia Sepulveda, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Phospho-SAPK/JNK (1:1000; 4668, Cell Signaling) anti-SAPK/JNK (1:1000 ...
• RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway

  Fang Huang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Akt (pan) (Cell Signaling Technology, #4691), anti-Phospho-NF-κB p65 (Cell Signaling Technology ...
• Co-Essentiality Analysis Identifies PRR12 as a Regulator of Cohesin and Genome Integrity

  Alexandra L. Nguyen, et al., bioRxiv - Cell Biology 2024

  Quote: ... SMC4 (1:500, Cell Signaling; D14E2), H3S10p (1:250 ...
• The expression of PKM1 and PKM2 in developing, benign, and cancerous prostatic tissues

  Lin Li, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Primary antibodies include PKM1 and PKM2 (7067S, dilution 1:500, and 4053S, dilution 1:1000, respectively, Cell Signaling Technology, Danvers, MA), p63 and FOXA2 (ab735 and ab108422 ...
• A high throughput CRISPR perturbation screen identifies epigenetic regulators impacting primordial germ cell development

  Liangdao Li, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and goat anti-rabbit IgG (1:2000, Cell signaling; 7074S) secondary antibodies were used for protein detection ...
• Filamin A mediates embryonical palatal fusion by linking mechanotransduction with β-Catenin/Smad2

  Ziyi Wang, et al., bioRxiv - Developmental Biology 2024

  Quote: ... with 20X LumiGLO® Reagent and 20X Peroxide (Cell Signaling, Danvers, MA, USA).
• The Role of Nde1 Phosphorylation in Interkinetic Nuclear Migration and Schizophrenia

  David J Doobin, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Antibodies used: anti phosphor-Thr(Pro) (Cell Signaling, 1:1000), anti Nde1 (generated as in Stehman et al. ...
• The long noncoding RNA lnc-FANCI-2 restricts RAS signaling and phosphorylation of Akt and Erk in HPV16-infected cervical cancer cells

  Haibin Liu, et al., bioRxiv - Cancer Biology 2024

  Quote: ... U0126 (Cell Signaling Technology, Danvers, MA, #9903) and examined for their proliferation and viability by CCK-8 assay and RAS effector expression by Western blot.
• Loss of NAT10 disrupts enhancer organization via p300 mislocalization and suppresses transcription of genes necessary for metastasis progression

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The antibodies used included anti-rabbit H3K27ac (0.16 μg) (Cell Signaling Technology), anti-rabbit H3K27me3 (0.51 μg ...
• Loss of NAT10 disrupts enhancer organization via p300 mislocalization and suppresses transcription of genes necessary for metastasis progression

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-rabbit HA (5 μg) (Cell Signaling Technology), anti-rabbit V5 (1:40 dilution ...