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9551 - 9600 of 10000+ citations for 6 METHYL 4 4 NITRO PHENYL 2 OXO 1 2 3 4 TETRAHYDRO PYRIMIDINE 5 CARBOXYLIC ACID ETHYL ESTER since 2019

• Partial inhibition of mitochondrial complex I attenuates neurodegeneration and restores energy homeostasis and synaptic function in a symptomatic Alzheimer’s mouse model

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... phospho-ULK1 (Ser555) (1:1000, Cell Signaling Technology, cat. #5869), phospho-ULK1 (Ser317 ...
• Electro-acupuncture Alleviates METH Withdrawal-induced Spatial Memory Deficits by Restoring Astrocyte-drived Glutamate Uptake in dCA1

  Pengbo Shi, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-c-Fos (1:2000; Cell Signaling Technology, USA), rabbit anti-SYP1 (Synaptotagmin-1 ...
• Compartment-Specific Neurexin Nanodomains Orchestrate Tripartite Synapse Assembly

  Justin H. Trotter, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-HA rabbit (Cell Signaling Cat#3724; 1:250 ICC), anti-Homer1 rabbit (Millipore Cat# ABN37 ...
• Directed Differentiation of Human Pluripotent Stem Cells into Radial Glia and Astrocytes Bypasses Neurogenesis

  Vukasin M. Jovanovic, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti LC3 A/B 1:50 (D3U4C, Cell Signaling), rabbit anti-ATG3 1:50 (3415 ...
• The SARS-CoV-2 receptor, Angiotensin converting enzyme 2 (ACE2) is required for human endometrial stromal cell decidualization

  Sangappa B. Chadchan, et al., bioRxiv - Cell Biology 2020

  Quote: ... and anti-GAPDH (1:3000, #2118S Cell Signaling Technology, USA) in 5% BSA in TBS-T overnight at 4°C ...
• Regulation of GluA1 Phosphorylation by D-amphetamine and Methylphenidate in the Cerebellum

  Laura Cutando, et al., bioRxiv - Neuroscience 2020

  Quote: ... horseradish peroxidase-conjugated antibodies (1:10000) from Cell Signaling Technology to rabbit (Cat# 7074S ...
• The DCC receptor regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation

  Laura Morcom, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-β-catenin (1:500, 9562, Cell signaling technology), mouse anti-β-dystroglycan (1:50 ...
• Developing Small Molecules that Inhibit K-Ras/GTP Binding Based on New Affinity Measurements

  Luca Carta, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 1 % NP40) from Active Ras Detection kit (Cell Signaling Technology) supplemented with Halt™ Protease & Phosphatase Inhibitor Cocktail (Thermo Scientific) ...
• Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma

  Xiuxiu Lu, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-K63 ubiquitin chain linkage (Cell Signaling, 5621s, 1/1000), anti-GST (Cell Signaling ...
• Pioglitazone improves deficits of Fmr1-KO mouse model of Fragile X syndrome by interfering with excessive diacylglycerol signaling

  Andréa Geoffroy, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-p-S6 (Ser235/236, 1/1000, 2211S Cell Signaling), anti-GAPDH (MAB374 ...
• Directing multicellular organization by varying the aspect ratio of soft hydrogel microwells

  Gayatri J. Pahapale, et al., bioRxiv - Bioengineering 2021

  Quote: ... and rabbit anti-Phospho-Paxillin (69363, Cell Signaling, 1:100). The secondary antibody was goat anti-rabbit antibody conjugated with Alexa Fluor 488 (A-11034 ...
• Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

  Thomas Kruse, et al., bioRxiv - Biochemistry 2021

  Quote: ... rabbit anti-G3BP1 (WB; 1:1000, Cell Signaling Technology, #17798S), mouse anti-G3BP1 (IF ...
• The mitotic checkpoint protein MAD2 delivers monoamine transporters to endocytosis

  Florian Koban, Michael Freissmuth, bioRxiv - Neuroscience 2021

  Quote: ... HRP-linked anti-rabbit IgG (1:5000; 7074S, Cell Signaling); IRDye 800CW goat-anti-Rabbit IgG (1:5000 ...
• Alterations in leptin signaling in Amyotrophic Lateral Sclerosis (ALS)

  Agueda Ferrer-Donato, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-phospho STAT3 (Tyr705) (1:500; Cell signaling); Rabbit anti-Suppressor of cytokine signaling 3 (SOCS3 ...
• Reduction of Nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43-related neurodegeneration

  Leon Tejwani, et al., bioRxiv - Neuroscience 2020

  Quote: ... and rabbit anti-phospho-S6 (Cell Signaling; #2215; 1:1000).
• Reduction of Nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43-related neurodegeneration

  Leon Tejwani, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-phospho-4E-BP1 (Cell Signaling; #2855; 1:1,000), rabbit anti- ULK1 (Cell Signaling ...
• Role of PARP1 in oligodendrocyte differentiation during developmental myelination and remyelination after myelin damage

  Yan Wang, et al., bioRxiv - Neuroscience 2021

  Quote: ... Gasdermin D (1:1000, 93709, RRID: AB_2800210, Cell Signaling Technology), MLKL (1:1000 ...
• SARS-CoV-2 spike protein induces brain pericyte immunoreactivity in absence of productive viral infection

  Rayan Khaddaj-Mallat, et al., bioRxiv - Neuroscience 2021

  Quote: ... and mouse anti-ACE2 (Cell Signaling Technology; 15983; 1/200). Afterwards ...
• The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling

  Sheng Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... or anti-rat (1:3000, RRID:AB_10694715, #7077, Cell Signaling Technology) secondary antibodies.
• GSAP Regulates Amyloid Beta Production through Modulation of Amyloid Precursor Protein Trafficking

  Jerry C. Chang, et al., bioRxiv - Neuroscience 2020

  Quote: ... Phospho-APP (Thr668) Antibody (1:1000, 3823S, Cell Signaling Technology), GSAP antibody (1:1000 ...
• CDNF rescues motor neurons in three animal models of ALS by targeting ER stress

  Francesca De Lorenzo, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-eIF2α (1:1000, 5324, Cell Signaling, MA, USA) anti-Chop (1:2000 ...
• ERα-LBD, a novel isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance

  Antonio Strillacci, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-β-actin 13E5 (Cell Signaling Technology, USA, 1:2000). Secondary antibodies (HRP conjugated) ...
• Breast tumor Insulin-like growth factor receptor regulates cell adhesion and metastasis: Alignment of mouse single cell and human breast cancer transcriptomics

  Alison E. Obr, et al., bioRxiv - Cancer Biology 2021

  Quote: ... phospho-Histone H3 (Ser10) (1:200; Cell Signaling, D2C8 XP), P-cadherin (1:100 ...
• Ferroptosis Regulation by the NGLY1/NFE2L1 Pathway

  Giovanni C. Forcina, et al., bioRxiv - Cell Biology 2021

  Quote: ... TCF11/NRF1/NFE2L1 D5B10 1:1000 (Cell Signaling Technology, 8052S); NGLY1 1:500 (Sigma-Aldrich ...
• Targeting Scavenger Receptor Type B1 In Cholesterol-Addicted Lymphomas Abolishes Glutathione Peroxidase 4 and Results in Ferroptosis

  Jonathan S. Rink, et al., bioRxiv - Cancer Biology 2020

  Quote: ... the β-actin antibody (Cell Signaling Technologies, AB_2223172; 1:3,000) and a secondary antibody (goat anti-rabbit HRP ...
• The level of oncogenic Ras controls the malignant transformation of Lkb1 mutant tissue in vivo

  Briana Rackley, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-phospho AKT (Ser 473) (Cell Signaling, 1:1000), mouse anti-phospho CaMKII (Thr 286 ...
• Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors

  Rupsa Datta, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or F4/80 (Cell Signaling Technologies #70076; 1:125 dilution) using standard techniques.
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Mouse anti-ß-Actin (Cell Signaling Technology # 58169; 1:1000), Mouse anti-ß-Tubulin (Sigma-Aldrich # T8328 ...
• RIPK2 Stabilizes c-Myc and is an Actionable Target for Inhibiting Prostate Cancer Metastasis

  Yiwu Yan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... phospho-c-Myc (Ser62) (1:1,000, Cell Signaling Technology #13748S), ubiquitin (K48-linkage specific ...
• RIPK2 Stabilizes c-Myc and is an Actionable Target for Inhibiting Prostate Cancer Metastasis

  Yiwu Yan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... fluorochrome-conjugated secondary antibody (1:1,000, Cell Signaling Technology #4408) was diluted in 2% BSA and incubated with the samples for 1 h at 37°C in the dark ...
• RIPK2 Stabilizes c-Myc and is an Actionable Target for Inhibiting Prostate Cancer Metastasis

  Yiwu Yan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ubiquitin (K48-linkage specific) (1:1,000, Cell Signaling Technology, #12805), FLAG (1:5,000 ...
• RIPK2 Stabilizes c-Myc and is an Actionable Target for Inhibiting Prostate Cancer Metastasis

  Yiwu Yan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... JNK (phospho-T183/Y185) (1:1,000, Cell Signaling Technology #9251S), mCherry (1:1,000 ...
• Targeting subtype-specific metabolic preferences in nucleotide biosynthesis inhibits tumor growth in a breast cancer model

  Martin P. Ogrodzinski, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 1:1000 dilution of anti-vinculin (Cell Signaling Technology, E1E9V). Anti-APRT and anti-vinculin antibodies were diluted in 5% bovine serum albumin and incubated overnight at 4 °C ...
• Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma

  Allison N. Lau, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or β-actin (Cell Signaling Technologies 8457, 1:10,000 dilution).
• Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice

  William Binning, et al., bioRxiv - Neuroscience 2020

  Quote: ... and anti-NeuN (1:1000, Cell Signaling, cat#D3S3I, RRID:AB_2630395). Secondary antibodies used include Alexa Fluor 555 goat anti-mouse (1:1000 ...
• Cerebellar dopamine D2 receptors regulate preference for social novelty

  Laura Cutando, et al., bioRxiv - Neuroscience 2019

  Quote: ... horseradish peroxidase-conjugated antibodies (1:10000) from Cell Signaling Technology to rabbit (Cat# 7074S ...
• LAMP3 is critical for surfactant homeostasis in mice

  Lars P. Lunding, et al., bioRxiv - Biochemistry 2021

  Quote: ... and donkey anti-mouse IgG HRP (1:2000, Cell Signaling) served as secondary Abs ...
• Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis

  Ayala Tovy, et al., bioRxiv - Cell Biology 2021

  Quote: ... Following primary antibody phospho-HSL (Ser660) 1:100 (Cell signaling) was added for overnight incubation ...
• A histidine cluster determines YY1-compartmentalized coactivators and chromatin elements in phase-separated super-enhancers

  Wenmeng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... H3K4me3 (Cell Signaling Technology, cat#9751, 1:200 for IF); H3K27ac (Abcam ...
• A histidine cluster determines YY1-compartmentalized coactivators and chromatin elements in phase-separated super-enhancers

  Wenmeng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... AKT (Cell Signaling Technology, cat#4685S, 1:1000 for WB); GAPDH (Acton ...
• A histidine cluster determines YY1-compartmentalized coactivators and chromatin elements in phase-separated super-enhancers

  Wenmeng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... H3K9me3 (Cell Signaling Technology, cat#13969, 1:500 for IF); pAKT-Thr308 (Cell Signaling Technology ...
• A histidine cluster determines YY1-compartmentalized coactivators and chromatin elements in phase-separated super-enhancers

  Wenmeng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... H3K4me1 (Cell Signaling Technology, cat#5326, 1:500 for IF); H3K4me3 (Cell Signaling Technology ...
• A histidine cluster determines YY1-compartmentalized coactivators and chromatin elements in phase-separated super-enhancers

  Wenmeng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... CDK9 (Cell Signaling Technology, cat#2316, 1:100 for IF); RNA Pol II-S2P (Millipore ...
• Toxoplasma gondii PPM3C, a secreted protein phosphatase, affects parasitophorous vacuole effector export

  Joshua A. Mayoral, et al., bioRxiv - Microbiology 2020

  Quote: ... IRF1 by rabbit anti-IRF1 (D5E4, Cell Signaling, 1:500), tachyzoite SAG1 by mouse anti-SAG1 (Thermo Fisher ...
• Dengue activates mTORC2 signaling to counteract apoptosis and maximize viral replication

  Christoph C. Carter, et al., bioRxiv - Microbiology 2020

  Quote: ... and 1× protease and phosphatase inhibitor cocktail (Cell Signaling Technology)) ...
• Operation of a TCA cycle subnetwork in the mammalian nucleus

  Eleni Kafkia, et al., bioRxiv - Systems Biology 2020

  Quote: ... rabbit anti-cytochrome c (1:1000, Cell Signaling Technology, #8674), rabbit anti-beta III tubulin (1:1000 ...
• Chicoric acid prevents neurodegeneration via microbiota-gut-brain axis in a mouse Parkinson’s disease model

  Ning Wang, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-NF-κB (1:1000, #8242, Cell Signaling Technology), rabbit anti-MyD88(1:1000 ...
• Identification of compounds enhancing Aqp4 stop codon readthrough

  D. Sapkota, J.D. Dougherty, bioRxiv - Neuroscience 2020

  Quote: ... incubated with anti-AQP4X (1:4000, Cell Signaling Technology, #60789) or anti-Vincullin (Abcam ...
• Drebrin mediates scar formation and astrocyte reactivity during brain injury by inducing RAB8 tubular endosomes

  Juliane Schiweck, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-integrin beta1 (Cell Signaling, #4706S, WB 1:1000), mouse anti-CD29 18/CD29 (BD Biosciences ...
• Inhibiting proBDNF to mature BDNF conversion leads to autism-like phenotypes in vivo

  He You, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-PSD-95 (1:1000; clone D27E11; Cell Signaling Technology), anti-SynGAP (1:1000 ...