Labshake search

9301 - 9350 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Endothelin B receptor inhibition rescues aging-dependent neuronal regenerative decline

  Rui Feng, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti- Connexin-43 (Cell Signaling, Catalog#: 3512s, 1:200); mouse anti TUJ1 (β-III tubulin ...
• KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes

  Xiaowen Xie, et al., bioRxiv - Molecular Biology 2024

  Quote: ... HDAC1 (Cell Signaling Technology, catalog no. 34589, D5C6U, 1:1,000), FLAG (Sigma-Aldrich ...
• Stress-induced dysfunction of neurovascular astrocytes contributes to sex-specific behavioral deficits

  Justin L. Bollinger, et al., bioRxiv - Neuroscience 2024

  Quote: ... or rabbit anti-ALDH1L1 (1:500, Cell Signaling Technologies, #85828), overnight at 4°C ...
• Modeling mTORopathy-related epilepsy in cultured murine hippocampal neurons using the multi-electrode array

  Anouk M. Heuvelmans, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-S6 Ribosomal Protein (1:2000 #2217 Cell Signaling), rabbit anti-TSC1 (1:1000 ...
• Lysosome damage triggers acute formation of ER to lysosomes membrane tethers mediated by the bridge-like lipid transport protein VPS13C

  Xinbo Wang, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-TBK1 (Cell Signaling Technology, 3504S; for WB, 1:2000), anti-pSer172 TBK1 (Cell Signaling Technology ...
• Lysosome damage triggers acute formation of ER to lysosomes membrane tethers mediated by the bridge-like lipid transport protein VPS13C

  Xinbo Wang, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-IKKe (Cell Signaling Technology, 3416S; for WB: 1:2000), anti-TBK1 (Cell Signaling Technology ...
• Drug-Induced p53 Activation Promotes Acinar Cell Identity and Prevents Pancreatic Cancer Initiation

  Jennifer J Twardowski, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit monoclonal anti-MIST1 (Cell Signaling Technology 14896T, 1:100), rabbit monoclonal anti-p-ERK1/2 (Cell Signaling Technology 4370S ...
• Patho-transcriptomic analysis of invasive mucinous adenocarcinoma of the lung (IMA): comparison with lung adenocarcinoma with signet ring cell features (SRCC)

  William D. Stuart, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and ALK (1:100 EDTA, Cell Signaling Technologies, Danvers, MA). RNAScope for NKX2-1 mRNA (Advanced Cell Diagnostics [ACD] ...
• Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor

  Patricia D.B. Tiburcio, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cleaved Caspase-9 (Cell Signaling Technology 7237, RRID:AB_10895832; 1:1,000), Cyclin D2 (Cell Signaling Technology 3741 ...
• Stat3-mediated Atg7 expression enhances anti-tumor immunity in melanoma

  Sarah M. Zimmerman, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Primary antibodies: anti-ATG7 (Cell Signaling #8558 at 1:500), anti-ACTIN (Abcam ab213262 at 1:1000) ...
• AKT2 modulates astrocytic nicotine responses in vivo

  Andrew M. Lombardi, et al., bioRxiv - Neuroscience 2024

  Quote: The pAKT2 antibody (Cell Signaling, #8599, used at 1:750), host species rabbit ...
• AKT2 modulates astrocytic nicotine responses in vivo

  Andrew M. Lombardi, et al., bioRxiv - Neuroscience 2024

  Quote: The GAPDH antibody (Cell Signaling, #5174, used at 1:1000), host species rabbit ...
• ErbB2/HER2 expression level determines CDK4-inhibitor sensitivity and cyclin D1 and c-Myc dependency at the G1/S transition

  Ayaka Nagasato-Ichikawa, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p-RB (Ser807/811; 1:1000; Cell Signaling Technology; #8516), p-RB (Thr373 ...
• ErbB2/HER2 expression level determines CDK4-inhibitor sensitivity and cyclin D1 and c-Myc dependency at the G1/S transition

  Ayaka Nagasato-Ichikawa, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p-ERK (Thr202 Tyr204; 1:1000; Cell Signaling Technology; #4370), HER2/ErbB2 (1:1000 ...
• Altered liver metabolism post-wean abolishes efficacy of vitamin D for breast cancer prevention in a mouse model

  Sarah M Bernhardt, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Cycle 2 F4/80 (Cell Signaling, 70076S, 1:500, 1hr), Cycle 3 CD45 (BD Pharmingen ...
• TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanisms

  Nicholas L Calistri, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 1:100 anti-cPARP-AF647 (#6987S, Cell Signaling Technology) or 1:500 anti-TUBB3-AF647 (#ab190575 ...
• Radiation-Induced Cellular Plasticity: A Strategy for Combatting Glioblastoma

  Ling He, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mixed with β3-tubulin (Cell Signaling Technology, #5568s, 1:400) overnight at 4°C ...
• Let-7 restrains an oncogenic epigenetic circuit in AT2 cells to prevent ectopic formation of fibrogenic transitional cell intermediates and pulmonary fibrosis

  Matthew J. Seasock, et al., bioRxiv - Cell Biology 2024

  Quote: ... Rabbit anti-Phospho-p70 S6K (1:200, Cell Signaling, 9234), Rabbit anti-pro-SFTPC (1:200 ...
• Stabilization of GTSE1 by cyclin D1-CDK4/6 promotes cell proliferation: relevance in cancer prognosis

  Nelson García-Vázquez, et al., bioRxiv - Biochemistry 2024

  Quote: ... p-RB (S807/811) (1:1,000, Cell Signaling Technology 9308S), SKP1 (1:5,000 ...
• Modification of Azithromycin to Mitigate its Arrest of Autophagy

  Ryan D Quarrington, et al., bioRxiv - Biochemistry 2024

  Quote: ... rabbit anti-TAX1BP1 (TAX; 1:2000, Cell Signaling Technology, #5105), rabbit anti-NDP52 (1:4000 ...
• Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis

  Erin E. Mulkearns-Hubert, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-c-MYC at 1:1000 dilution (Cell Signaling, 9402S), Na/K ATPase at 1:2000 (ThermoFisher Scientific ...
• Staphylococcus warneri dampens SUMOylation and promotes intestinal inflammation

  Léa Loison, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-SAE1 (#13585, Cell Signaling Technology, 1:1,000 dilution), rabbit anti-SAE2 (D15C11 ...
• Staphylococcus warneri dampens SUMOylation and promotes intestinal inflammation

  Léa Loison, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-SAE2 (D15C11, Cell Signaling Technology, 1:1,000 dilution) and rabbit anti-SUMO3 (R205 (is2)27 ...
• Theca cell mechanics and tissue pressure regulate mammalian ovarian folliculogenesis

  Arikta Biswas, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-phospho histone H3 (Cell Signaling Technology, 1:100), rabbit anti-cleaved caspase 3 (Abcam ...
• Oxygen-releasing nanodroplets relieve intratumoral hypoxia in head and neck cancer spheroids

  Marvin Xavierselvan, et al., bioRxiv - Bioengineering 2024

  Quote: ... HIF-1α (dilution: 1:1000, Cat: 3716, Cell Signaling Technology), and HIF-2α (dilution ...
• Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related multisystem neurodegenerative deficits

  Ariadna Laguna, et al., bioRxiv - Neuroscience 2024

  Quote: ... together with Hoechst 33342 (1:10000, Cell Signaling Technology; RRID:AB_10626776) to stain nuclei ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... cells were incubated with α-Tubulin (1:45; Cell Signaling) diluted in blocking buffer and incubated for 1 hour at RT ...
• The main duct of von Ebner’s glands is a source of Sox10⁺ taste bud progenitors and susceptible to pathogen infections

  Wenxin Yu, et al., bioRxiv - Cell Biology 2024

  Quote: ... or Plp1 (1:500, #28702, Cell Signaling Technology, Danvers, MA) diluted with 0.1 M PBS containing 0.3% Triton X-100 and 1% normal donkey serum ...
• P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by Borrelia burgdorferi

  Michal Caspi Tal, et al., bioRxiv - Immunology 2024

  Quote: ... HRP-linked secondary antibody (1:1,000 dilution, Cell Signaling Technology) (1 h ...
• Wnt signaling dosage controlled by a Ctnnb1 enhancer balances homeostasis and tumorigenesis of intestinal epithelia

  Xiaojiao Hua, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-β-catenin (Cell Signaling Technology, 8480T, 1:100), rabbit anti-Muc2 (Thermo Fisher Scientific ...
• Depletion of TDP-43 exacerbates tauopathy-dependent brain atrophy by sensitizing vulnerable neurons to caspase 3-mediated endoproteolysis of tau in a mouse model of Multiple Etiology Dementia

  Meghraj S Baghel, et al., bioRxiv - Neuroscience 2024

  Quote: ... antiserum against Tau4R (E7T4F) (1:1000; 79327, Cell Signaling Technology); antiserum against cleaved Caspase 3 (1:2000 ...
• Delineation of a thrombin receptor-stimulated vascular smooth muscle cell transition generating cells in the plaque-stabilising fibrous cap

  James CK Taylor, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and GAPDH (loading control, Cell Signaling Technologies, 2118, 1:4000) were detected using HRP-labelled secondary antibodies ...
• An in vitro assay of MCTS1-DENR-dependent re-initiation and ribosome profiling uncover the activity of MCTS2 and distinct function of eIF2D

  Romane Meurs, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit anti-phospho-eIF2alpha (Ser51) 1:1000 (#9721S, Cell Signaling), mouse anti-FLAG 1:10000 (M2F3165 ...
• FDA-approved PDE4 inhibitors reduce the dominant toxicity of ALS–FTD-associated CHCHD10^S59L

  Swati Maitra, et al., bioRxiv - Neuroscience 2024

  Quote: ... PINK1 & TOM20 (Cell Signaling and Santa Cruz Biotechnology, 1:250), LC3B (Cell Signaling Technology ...
• Asymmetric Engagement of Dimeric CRL3^KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes

  Megan J.R. Yeo, et al., bioRxiv - Molecular Biology 2024

  Quote: ... HDAC1 (Cell Signaling Technology, catalog no. 34589, D5C6U, 1:1,000), HDAC2 (Cell Signaling Technology ...
• KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes

  Xiaowen Xie, et al., bioRxiv - Molecular Biology 2024

  Quote: ... His- tag (Cell Signaling Technology, catalog no. 2365, 1:1,000), HA-tag (Cell Signaling Technology ...
• Asymmetric Engagement of Dimeric CRL3^KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes

  Megan J.R. Yeo, et al., bioRxiv - Molecular Biology 2024

  Quote: ... His-tag (Cell Signaling Technology, catalog no. 2365, 1:1,000), HA-tag (Cell Signaling Technology ...
• Asymmetric Engagement of Dimeric CRL3^KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes

  Megan J.R. Yeo, et al., bioRxiv - Molecular Biology 2024

  Quote: ... HDAC2 (Cell Signaling Technology, catalog no. 57156, D6S5P, 1:1,000), FLAG (Sigma-Aldrich ...
• Stomatin-like protein 2 senses oxidative stress through the interaction with phosphatidic acid to promote mitochondrial unfolded protein response

  Maria Paulina Castelo Rueda, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and rabbit anti-β actin (Cell Signaling. #4967; 1:1000).
• In vivo CRISPR base editing for treatment of Huntington’s disease

  Shraddha Shirguppe, et al., bioRxiv - Bioengineering 2024

  Quote: ... and mouse anti-GFAP (1:200; Cell Signaling Technology, #3670)).
• PIEZO1-Mediated Mechanotransduction Regulates Collagen Synthesis on Nanostructured 2D and 3D Models of Fibrosis

  Neda Rashidi, et al., bioRxiv - Bioengineering 2024

  Quote: ... Primary antibodies for YAP (Cell signaling, Danvers, MA, 1:200), PIEZO1 (Novus Biologicals ...
• Translation-independent association of mRNAs encoding protomers of the 5-HT_2A-mGlu2 receptor complex in living cells

  Somdatta Saha, Javier Gonzalez-Maeso, bioRxiv - Biochemistry 2024

  Quote: ... anti-GAPDH (Cell Signaling technology, catalog no. 2118, 1:1000), anti-Lamin A/C (Cell Signaling technology ...
• Translation-independent association of mRNAs encoding protomers of the 5-HT_2A-mGlu2 receptor complex in living cells

  Somdatta Saha, Javier Gonzalez-Maeso, bioRxiv - Biochemistry 2024

  Quote: ... anti-HA (Cell Signaling technology, catalog no. 2367, 1:1000), anti-GAPDH (Cell Signaling technology ...
• Stabilization of GTSE1 by cyclin D1-CDK4/6 promotes cell proliferation: relevance in cancer prognosis

  Nelson García-Vázquez, et al., bioRxiv - Biochemistry 2024

  Quote: ... p-cyclin D1 (T286) (1:1,000, Cell Signaling Technology 3300S), cyclin E (1:1,000 ...
• CD28 Shapes T Cell Receptor Signaling by Regulating ZAP70 Activation and Lck Dynamics

  Kumarkrishna Raychaudhuri, et al., bioRxiv - Immunology 2024

  Quote: ... anti-p-PLCγ-1-Y783 (Cell Signaling, Cat. No. 2821S) and anti-p-Erk-T202/Y205 (Cell Signaling ...
• Reorganization of innate immune cell lipid profiles by bioinspired meroterpenoids to limit inflammation

  Lorenz Waltl, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... rabbit anti-phospho-MEK1/2 (1:1000; #9121; Cell Signaling), goat anti-FLAP (1:1000 ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... p44/42 MAPK (Erk1/2) (#4695, Cell signaling, 1:1000), ROCK2 (#8236 ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... Phospho-p38 MAPK (Thr180/Tyr182) (#9211, Cell signaling, 1:1000), p38 MAPK (#9212 ...
• Targeting of a STING Agonist to Perivascular Macrophages in Prostate Tumors Delays Resistance to Androgen Deprivation Therapy

  Haider Al-janabi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and a mouse anti-human CD31/PECAM-1 (Cell Signaling). All three were conjugated to fluorophores and diluted with 3% (wt/vol ...
• LHPP expression in triple-negative breast cancer promotes tumor growth and metastasis by modulating the tumor microenvironment

  Jeffrey Reina, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-F4/80 (Cell Signaling Technology, 70076, 1:200), and rabbit anti-Ki67 (Abcam ...