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8951 - 9000 of 10000+ citations for Human High Sensitive Leucine Rich Alpha 2 Glycoprotein 1 LRG1 CLIA Kit since 2019

• ULK1-regulated AMP sensing by AMPK and its application for the treatment of chronic kidney disease

  Tomoki Yanagi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-phospho-AMPKα (pThr172) (1:1,000, #2535, Cell Signaling Technology), anti-AMPKβ1 (1:1,000 ...
• ULK1-regulated AMP sensing by AMPK and its application for the treatment of chronic kidney disease

  Tomoki Yanagi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-phospho-Raptor (Ser792) (1:1,000, #2083, Cell Signaling Technology), and anti-phospho-AMPKγ1 ...
• Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance

  Stewart W.C. Masson, et al., bioRxiv - Systems Biology 2023

  Quote: ... phosphorylated Akt S473 (Cell Signaling Technologies #9271; diluted 1:1000), pan-Akt (Cell Signaling Technologies #9272 ...
• Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance

  Stewart W.C. Masson, et al., bioRxiv - Systems Biology 2023

  Quote: ... phosphorylated PRAS40 T246 (Cell Signaling Technologies #13175; diluted 1:1000), PRAS40 (Cell Signaling Technologies #2691 ...
• Activation of goblet cell stress sensor IRE1β is controlled by the mucin chaperone AGR2

  Eva Cloots, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-AGR2 (Cell Signaling Technologies, Clone D9V2F, 1/1000).
• Rare catechol-O-methyltransferase (COMT) missense variants are structurally unstable proteasome targets

  Fia B. Larsen, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-LC3a/b (diluted 1:2000) (Cell Signaling Technology, D3U4C), anti-mCherry (diluted 1:1000 ...
• Cyclone: an accessible pipeline to analyze, evaluate and optimize multiparametric cytometry data

  Ravi K. Patel, et al., bioRxiv - Immunology 2023

  Quote: ... and EpCAM (1:50, clone: D9S3P, from Cell Signaling technology). The tissue was counterstained with DAPI (Akoya cat ...
• Epithelial multicellular clustering enabled by polarized macrophages on soft matrices

  Hannah Zmuda, Amit Pathak, bioRxiv - Bioengineering 2023

  Quote: ... Anti-Catenin-d1 (P120; 1:800; Cell Signaling Technology: 59854), and non-muscle myosin-2A conjugated with Alexa 647 (NM2A ...
• Isoform-specific targeting properties of the protocadherin CDHR5 control its apical delivery to promote brush border assembly

  Samaneh Matoo, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-P-ERM (1:200; Cell Signaling catalog no. 3726) or anti-GFP (1:200 ...
• Antigen-presenting type-I conventional dendritic cells facilitate curative checkpoint blockade immunotherapy in pancreatic cancer

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-mouse CD11c (Cell Signaling Technology, CST 97585S, 1:350), anti-human CD11c (Abcam ...
• Cellular mechanisms of heterogeneity in NF2-mutant schwannoma

  Christine Chiasson-MacKenzie, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-merlin rabbit mAb (1:100; D1D8, Cell Signaling Technology); anti-pS6 (S235/236 ...
• Oxygen-independent, hormonal control of HIF-1α regulates the developmental and regenerative growth of cardiomyocytes

  Amarylis C.B.A. Wanschel, et al., bioRxiv - Developmental Biology 2023

  Quote: ... using antibodies against: HIF-1α (1:2000; D1S7W, Cell Signaling), GHRH-R (1:500 ...
• Platelet pannexin-1 channels modulate inflammation during abdominal aortic aneurysm formation

  Lisa Maria Metz, et al., bioRxiv - Cell Biology 2022

  Quote: ... glyceraldehyde 3-phosphate dehydrogenase (GAPDH, #2118S, Cell Signaling, 1:1000) and horseradish peroxidase (HRP)-linked anti-rabbit secondary antibodies (#7074S ...
• Lethal giant larvae gene family (Llgl1 and Llgl2) functions as a tumor suppressor in mouse skin epidermis

  Victor M. Bii, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-p-IKKα/β (1:500, Cell Signaling, #2697), rabbit anti-IKKβ (1:1000 ...
• Lethal giant larvae gene family (Llgl1 and Llgl2) functions as a tumor suppressor in mouse skin epidermis

  Victor M. Bii, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-p-RelA-p65 (1:1000, Cell Signaling, #8242); mouse anti-aPKC (1:1000 ...
• BIRC5 Regulates IGFBP-3-Induced Autocrine Loop in Cancer Stem Cells

  Yeon-Jee Kahm, Uhee Jung, Rae-Kwon Kim, bioRxiv - Cancer Biology 2023

  Quote: ... Sox2 (cat. no. 3579; Cell Signaling Technology, Inc., 1:1000), Oct-4 (cat ...
• BIRC5 Regulates IGFBP-3-Induced Autocrine Loop in Cancer Stem Cells

  Yeon-Jee Kahm, Uhee Jung, Rae-Kwon Kim, bioRxiv - Cancer Biology 2023

  Quote: ... Nanog (cat. no. 4893; Cell Signaling Technology, Inc., 1:1000), ZEB1 (cat ...
• Myeloperoxidase enhances the migration of human choriocarcinoma JEG-3 cells¹

  ZN. Mihalic, et al., bioRxiv - Cell Biology 2023

  Quote: ... A primary rabbit anti-MPO antibody (Cell Signaling, 1:500) in 1:10 blocking solution + 0.1% Triton X-100 was added and incubated overnight at 4°C ...
• Propionate reinforces epithelial identity and reduces aggressiveness of non-small cell lung carcinoma via chromatin remodelling

  Vignesh Ramesh, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and β-Actin HRP conjugated (1:10000, Cell Signaling, 12262). Next day ...
• MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression

  Jiayu Chen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mouse anti-β-Actin antibody (3700, Cell Signaling, 1:5000). Fluorescent secondary antibodies used in this study were IRDye 680RD Donkey anti-Mouse IgG Secondary Antibody and IRDye 800CW Donkey anti-Rabbit IgG Secondary Antibody (Licor ...
• The cancer-specific lncRNA LISR customizes ribosomes to suppress anti-tumour immunity

  Sonia Cinque, et al., bioRxiv - Cancer Biology 2023

  Quote: ... eIF2α-Tot (#5324, clone D7D3; Cell Signaling Technology, 1:1,000), eIF2α-Phospho-S51 (#3398 ...
• Human papillomavirus 16 E2 interaction with TopBP1 is required for E2 and viral genome stability during the viral life cycle

  Apurva T. Prabhakar, et al., bioRxiv - Cancer Biology 2023

  Quote: ... phospho-γH2AX 1:1000 (Cell Signaling Technology, catalog no. 9718), HPV16 E7 1:200 (Santa Cruz ...
• Cooperative NF-κB and Notch1 signaling promotes macrophage-mediated MenaINV expression in breast cancer

  Camille L. Duran, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Lamin A/C (1:1000, Cell Signaling Technologies, cat# 2032), or GAPDH (1:10,000 ...
• PTPN1 deficiency modulates BMPR2 signaling and induces endothelial dysfunction in Pulmonary Arterial Hypertension

  Md Khadem Ali, et al., bioRxiv - Cell Biology 2022

  Quote: ... with primary antibodies PTP1b (Cat # CST5311, Cell Signaling, 1:1000), BMPR2 (Cat # MA5-15827 ...
• Intermediate filament dysregulation and astrocytopathy in the human disease model of KLHL16 mutation in giant axonal neuropathy (GAN)

  Rachel Battaglia, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-Vimentin (Cell Signaling Technology, D21H3, IF 1:100), mouse anti-Vimentin (Thermo Fisher Scientific ...
• Tau tubulin kinase 1 and 2 regulate ciliogenesis and human pluripotent stem cells–derived neural rosettes

  Lucia Binó, Lukáš Čajánek, bioRxiv - Cell Biology 2023

  Quote: ... Phospho-Histone H3 Thr11 (rabbit, #9764 Cell Signaling, 1:300). Coverslips were then washed 3x 5min in PBS and stained with donkey-raised secondary antibodies in either blocking buffer or 0,2% Triton-X100 in PBS ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-CD31 antibody (1:100, Cat# 77699, Cell signaling), respectively ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho-Akt (Ser473) (1:500; Cat# 9271, Cell Signaling), anti-Akt (1:1000 ...
• Multi-omic screening of invasive GBM cells in engineered biomaterials and patient biopsies reveals targetable transsulfuration pathway alterations

  Joseph H. Garcia, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and probed with anti-CTH (Cell Signaling #30068, 1:1000) and anti-GAPDH (Cell Signaling #5174 ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-ubiquityl-PCNA (Lys164) (1:1000; Cat# 13439, Cell Signaling), anti-ubiquitin Lys63-specific (1:1000 ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-phospho-Chk1 (Ser345) (1:2000; Cat# 2348, Cell Signaling), anti-phospho-histone H3 (Ser10 ...
• Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

  Yi-Chang Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-lamin A/C (1:2000, Cat# 4777, Cell Signaling), anti-BRCA2 (1:3000 ...
• ARID1A-deficient cells promote endometrial carcinoma progression and dissemination by reprograming tumor microenvironment

  Cristina Megino-Luque, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-COL1A (1:200, Triton X-100; Cell signaling 39952); anti-p-MLY2 (Ser19 ...
• Lineage plasticity enables low-ER luminal tumors to evolve and gain basal-like traits

  Gadisti Aisha Mohamed, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-GFP (Cell Signaling, 2956, clone: D5.1, 1:150 dilution) with Opal 650 (1:500 dilution) ...
• A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation

  Katherine J. Susa, et al., bioRxiv - Immunology 2023

  Quote: ... or Phospho-CD19 (Tyr531) antibody (Cell Signaling, 1:1000 dilution) in TBST containing 1% BSA ...
• A Cas9-fusion proximity-based approach generates an Irak1-Mecp2 tandem duplication mouse model for the study of MeCP2 duplication syndrome

  Eleonora Maino, et al., bioRxiv - Genetics 2023

  Quote: ... rabbit monoclonal D51G7 anti-IRAK1 (#4504, Cell Signaling, 1:1000), rabbit monoclonal anti-GAPDH (sc-47724 ...
• The myocardium utilizes Pdgfra-PI3K signaling to steer towards the midline during heart tube formation

  Rabina Shrestha, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and pan-AKT (1:2000, Cell Signaling 4691, RRID: AB_915783), Anti-rabbit HRP-conjugated (1:5000 ...
• The phosphodiesterase 2A regulates lymphatic endothelial development via cGMP-mediated control of Notch signaling

  Claudia Carlantoni, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-β-actin (Cat#: 4970, Cell Signaling, 1:1000), and anti-PROX1 (Cat# ...
• Intrinsic microtubule destabilization of multiciliated choroid plexus epithelial cells during postnatal lifetime

  Kim Hoa Ho, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-acetylated α-tubulin (1:800, #5335T, Cell Signaling), mouse anti-glutamylated tubulin GT335 (1:800 ...
• Control of gastruloid patterning and morphogenesis by the Erk and Akt signaling pathways

  Evan J. Underhill, Jared E. Toettcher, bioRxiv - Developmental Biology 2023

  Quote: ... Snail C15D3 rabbit (Cell Signaling Technology, 3879, 1:50 dilution), E-cadherin 24E10 rabbit (Cell Signaling Technology ...
• Mob4 is essential for spermatogenesis in Drosophila melanogaster

  Inês B. Santos, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and anti-cleaved caspase 3 (1:500, Cell Signaling #9661). The samples were washed thrice in PBST for 20 min and incubated with appropriate secondary antibodies in a humid chamber for 2 h at room temperature ...
• Dysregulated CD38 expression in blood and skin immune cells of patients with hidradenitis suppurativa

  Peter Dimitrion, et al., bioRxiv - Immunology 2023

  Quote: ... and CD14 (Cell Signaling D7A22T; 1:250, TRS-low pH) on a Dako Autostainer Link ...
• Gestational diabetes mellitus dysregulates the PD-1/PD-L1 axis at the feto-maternal interface

  ZN. Mihalic, et al., bioRxiv - Immunology 2023

  Quote: ... Anti-PD-L1 (clone E1L3N, 1:1000 dilution, Cell Signaling) and anti-GAPDH (clone 14C10 ...
• Gestational diabetes mellitus dysregulates the PD-1/PD-L1 axis at the feto-maternal interface

  ZN. Mihalic, et al., bioRxiv - Immunology 2023

  Quote: ... and anti-GAPDH (clone 14C10, 1:500 dilution, Cell Signaling) monoclonal antibodies were used ...
• Mitochondrial metabolism in Drosophila macrophage-like cells regulates body growth via modulation of cytokine and insulin signaling

  Shrivani Sriskanthadevan-Pirahas, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and anti-phospho-JNK (1:500, Cell Signaling Technolog #4668S). Goat and donkey secondary antibodies were purchased from Santa Cruz Biotechnology (sc-2030 ...
• Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10

  Caterina Ivaldo, et al., bioRxiv - Cell Biology 2022

  Quote: ... and anti-β-catenin (rabbit, Cell Signaling Technology, 1:100) antibodies were used followed by specific secondary Alexa Fluor antibodies (1:500 anti-mouse Alexa Fluor 546 and 1:500 anti-rabbit Alexa 488 Thermo Fisher) ...
• The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis

  Bianca M. Lupan, et al., bioRxiv - Developmental Biology 2023

  Quote: ... as well as Ki67 (Cell Signaling Technology, 12202, 1:250).
• Partial Activation of PPAR-γ by Synthesized Quercetin Derivatives Modulates TGF-β1-Induced EMT in Lung Cancer Cells

  Sangeeta Ballav, Amit Ranjan, Soumya Basu, bioRxiv - Cancer Biology 2022

  Quote: ... and anti-Zeb-1 (rabbit, Cell Signaling Technology, CA, USA). Anti-rabbit and anti-mouse antibodies conjugated to horseradish peroxidase (HRP ...
• A multifunctional Wnt regulator underlies the evolution of coat pattern in African striped mice

  Matthew R. Johnson, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Primary antibodies rabbit anti-LEF1 (Cell signaling #2230S, 1:100), rabbit anti-β-catenin (Sigma # C2206 ...
• Spatiotemporal analysis of SARS-CoV-2 infection reveals an expansive wave of monocyte-derived macrophages associated with vascular damage and virus clearance in hamster lungs

  Ola Bagato, et al., bioRxiv - Immunology 2023

  Quote: ... rabbit anti-Cleaved Caspase-3 (Cell Signaling, #9661, 1:200), rabbit anti-Uteroglobin (Abcam ...