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8901 - 8950 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Cytoplasmic protein-free mRNA induces stress granules by two G3BP1/2-dependent mechanisms

  Sean J. Ihn, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-FMRP (rabbit polyclonal, 1:50 dilution, Cell Signaling Technology), anti-PABP (rabbit polyclonal ...
• Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency

  Chikako Okubo, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit monoclonal anti-ERK1/2 (1:50, Cell Signaling Technology), rabbit monoclonal anti- phospho-ERK1/2 (Thr202/Tyr204 ...
• mTORC3 activity is regulated by GSK3β through the activation of PKCδ that phosphorylates and activates STAT1

  Jun Zhan, et al., bioRxiv - Cell Biology 2024

  Quote: ... and leupeptin (1 µg/ml) (Cell Signaling Technologies, Thermo Fisher)] supplemented with 1 mM phenylmethylsulfonyl fluoride (PMSF) ...
• Chlamydia trachomatis modulates the expression of JAK-STAT signaling components to attenuate the Type II interferon response of epithelial cells

  Francis L. Fontanilla, et al., bioRxiv - Microbiology 2024

  Quote: ... JAK2 XP (Cell Signaling Technologies 3230-CST, 1:500 dilution), IDO1 (Cell Signaling Technologies 86630 ...
• Chlamydia trachomatis modulates the expression of JAK-STAT signaling components to attenuate the Type II interferon response of epithelial cells

  Francis L. Fontanilla, et al., bioRxiv - Microbiology 2024

  Quote: ... pJAK2-Tyr1008 (Cell Signaling Technologies 8082-CST, 1:500 dilution), JAK2 XP (Cell Signaling Technologies 3230-CST ...
• Lamin B Receptor Upregulation in Metastatic Melanoma Causes Cholesterol-Mediated Nuclear Envelope Fragility

  Michelle A. Baird, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-GAPDH (1:2000; Clone 14C10, Cell Signaling, 2118S). The secondary antibodies (HRP-conjugated goat anti-mouse (115-035-003 ...
• Production of OSU G5P[7] Porcine Rotavirus Expressing a Fluorescent Reporter by Reverse Genetics

  Anthony J. Snyder, et al., bioRxiv - Microbiology 2024

  Quote: ... or β-actin antibody (D6A8, Cell Signaling Technology, 1:2000). The bound primary antibodies were detected using 1:10,000 dilutions of horseradish peroxidase (HRP)-conjugated secondary antibodies (goat anti-mouse IgG [CST] ...
• The interferon-ɣ inducible factor 16 (IFI16) restricts adeno-associated virus serotype 2 (AAV2) transduction in an immune-modulatory independent way

  Sereina O. Sutter, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-E2F1 (Cell Signaling 3742; dilution for WB; 1:1‘000), anti-p53 (Abcam ...
• Lysine Demethylase 4A is a Centrosome Associated Protein Required for Centrosome Integrity and Genomic Stability

  Pratim Chowdhury, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-lamin A/C (1:2000, Cell Signaling, Cat. # 2032S), anti-SETD2 (1:1000 ...
• The transcriptional response of cortical neurons to concussion reveals divergent fates after injury

  Mor R. Alkaslasi, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-phospho-H2AX (1:400, Cell Signaling Tech., 2577), rabbit anti-Olig2 (1:500 ...
• Non-canonical induction of autophagy increases adeno-associated virus type 2 (AAV2) transduction efficiency

  Sereina O. Sutter, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-Atg13 (Cell signaling 13468: dilution for WB, 1:200), anti-AAV2 intact particle (A20 ...
• Cell circuits underlying nanomaterial specific respiratory toxicology

  Carola Voss, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... or AM marker (rabbit CD11c, 1:200, Cell Signaling, #97585). Olympus BX51 fluorescence microscopy was used for direct visualization of dUTP-labeled DNA ...
• Lipid Dysregulation Unveil the Intricate Interplay of Lysosomal and Mitochondrial Changes in Frontotemporal Dementia with GRN Haploinsufficiency

  Jon Ondaro, et al., bioRxiv - Neuroscience 2024

  Quote: ... HRP-linked Antibody (1:5 000, 7076, 7074, Cell Signaling) or fluorescent secondary antibodies were used at 1/5 000 ...
• Condensin-mediated restriction of retrotransposable elements facilitates brain development in Drosophila melanogaster

  Bert I. Crawford, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-phospho-histone H3 ser10 (Cell Signaling 9701; 1:500), anti-prospero (Developmental Studies Hybridoma Bank MR1A ...
• TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes

  Yi Zeng, et al., bioRxiv - Neuroscience 2024

  Quote: ... or GAPDH (D16H11) XP (1:1000, Cell Signaling Technology 8884S). Membranes were subsequently incubated in blocking buffer containing horseradish peroxidase (HRP)-conjugated anti-mouse IgG (H+L ...
• Chromatin regulator Kdm6b is required for the establishment and maintenance of neural stem cells in mouse hippocampus

  Eugene Gil, et al., bioRxiv - Neuroscience 2024

  Quote: ... and anti-H3K27m3 (Cell Signaling Technologies, no. 9733, 1:100) An IgG control was run in parallel for each experiment (Cell Signaling Technologies ...
• Alpha-synuclein-induced nigrostriatal degeneration and pramipexole treatment disrupt frontostriatal plasticity

  Sarah Chevalier, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1/800 to TrkB (Cell Signaling Technology, Leiden, The Netherlands) and 1/8000 to alpha-tubulin (Sigma-Aldrich ...
• Conditional knockout of Shank3 in the ventral CA1 by quantitative in vivo genome-editing impairs social memory

  Myung Chung, et al., bioRxiv - Neuroscience 2024

  Quote: ... and rabbit anti-Shank3 (64555, 1:500; Cell Signaling Technology). After washing with PBS (- ...
• Atacama Clear for Complex 3D Imaging of Organs

  Neranjan de Silva, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-Pdgfr-β (3169, Cell Signaling Technology, at 1:100), anti-CD31 (BD Biosciences ...
• Fluoxetine treatment during postnatal and juvenile temporal epochs evokes diametrically opposing changes in anxio-depressive behaviors, gene expression, mitochondrial function, and neuronal architecture in the medial prefrontal cortex

  Utkarsha Ghai, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit phosphorylated p-70 S6K (1:250, Cell Signaling Technologies), rabbit actin (1:5000 ...
• The calcium pump PMCA4b promotes epithelial cell polarization and lumen formation

  Sarolta Tóth, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-E-cadherin (CST 3195, Cell Signaling, dilution 1:1000), anti-N-cadherin (sc-8424 ...
• Loss of TIM4-Dependent Efferocytosis in Kupffer Cells Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis

  Hongxue Shi, et al., bioRxiv - Pathology 2024

  Quote: ... anti-F4/80 (Cell signaling technology, #70076s, RRID:AB_2799771, 1:200), anti-osteopontin (Opn ...
• Human assembloid model of the ascending neural sensory pathway

  Ji-il Kim, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-TCF7L2 (rabbit, Cell Signaling Technology, 2569S, 1:200 dilution), anti-PHOX2A (rabbit ...
• FoxO transcription factors actuate the formative pluripotency specific gene expression programme

  Laura Santini, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 1:1000 for anti-pan-Akt (rabbit; Cell Signaling, 4691), 1:1000 for anti-phospho-GSK3β(Ser9 ...
• FoxO transcription factors actuate the formative pluripotency specific gene expression programme

  Laura Santini, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 1:1000 for anti-4E-BP1 (rabbit; Cell Signaling, 9644), 1:1000 for anti-phospho-p70 S6 kinase(Thr389 ...
• FoxO transcription factors actuate the formative pluripotency specific gene expression programme

  Laura Santini, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and 1:1000 for anti-FoxO3a (rabbit; Cell Signaling, 2497). The following primary antibodies were diluted in PBS-T containing 5% milk and used 1:1000 for anti-NANOG (rabbit ...
• Generation of Systemic Chimeras via Rabbit Induced Pluripotent Stem Cells Reprogrammed with KLF2, ERAS, and PRMT6

  Florence Perold, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Phospho-Akt (Ser473) (Cell Signaling, ref #4060, 1:1000), and anti-beta-actin (Sigma-Aldrich ...
• Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway

  Ryosuke Isotani, et al., bioRxiv - Cell Biology 2024

  Quote: ... and rabbit anti-β-catenin (1/200; 9562; Cell Signaling). For samples incubated with mouse primary antibodies ...
• Vascular damage and excessive proliferation compromise liver function after extended hepatectomy in mice

  Maxime De Rudder, et al., bioRxiv - Cell Biology 2024

  Quote: ... We used antiCD31 antibody (77699S, Cell Signaling, diluted 1/200) to detect endothelial cells ...
• Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2

  Ling Xu, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-ACE2 (Cell Signaling Technology, USA, #74512, 1:100), mouse anti-GFP (Santa Cruz Biotechnology ...
• Morphological Reprogramming of Primary Cilia Length Mitigates the Fibrotic Phenotype in Fibroblasts Across Diverse Fibrotic Conditions

  Priyanka Verma, et al., bioRxiv - Cell Biology 2024

  Quote: ... Acetyl-α-Tubulin (Cell Signaling #5335, Danvers, MA 1:500) and ARL13b (Proteintech ...
• Caspase cleavage of Influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production

  Carmen Figueras-Novoa, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit polyclonal caspase-6 (Cell Signaling, 9762, WB 1:1000), mouse monoclonal anti-β-actin (Proteintech ...
• Downstream-of-gene (DoG) transcripts contribute to an imbalance in the cancer cell transcriptome

  Pedro A. Avila-Lopez, et al., bioRxiv - Genomics 2024

  Quote: ... anti-Rpb1 NTD (D8L4Y) (Cell Signaling, #14958, 1:1000 dilution).
• Rbpms2 promotes female fate upstream of the nutrient sensing Gator2 complex component, Mios

  Miranda L. Wilson, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-p-p70s6k (1:500 dilution; Cell Signaling, 9205), rabbit anti-Mios (1:500 dilution ...
• NOTUM-MEDIATED WNT SILENCING DRIVES EXTRAVILLOUS TROPHOBLAST CELL LINEAGE DEVELOPMENT

  Vinay Shukla, et al., bioRxiv - Developmental Biology 2024

  Quote: ... phosphorylated CTNNB1 (1:1000, Ser33/37/Thr41, 9561 Cell Signaling), EPAS1 (1:300 ...
• HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis

  Fengmei Xu, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-HA (Cell Signaling Technology [C29F4], 3724, 1:1,000). Horseradish peroxidase (HRP)-conjugated secondary antibodies used were goat anti-rabbit IgG or anti-mouse IgG (Bio-Rad ...
• SMA Type II Skeletal Muscle Treated with Nusinersen shows SMN Restoration but Mitochondrial Deficiency

  Fiorella Carla Grandi, et al., bioRxiv - Genetics 2024

  Quote: ... anti-phospho (Ser15)-p53 (1:1000, Cell Signaling Cat#92845), or anti-GADD45A (1:1000 ...
• DDR1 regulates RUNX1-CBFβ to control breast stem cell differentiation

  Colin Trepicchio, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and Goat anti-Mouse (7076, Cell Signaling Technology, 1:1000).
• Merkel cell polyomavirus protein ALTO modulates TBK1 activity to support persistent infection

  Ranran Wang, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-TBK1 p-S172 (1:1000, 5483S, Cell Signaling Technology), anti-P65 (1:1000 ...
• Merkel cell polyomavirus protein ALTO modulates TBK1 activity to support persistent infection

  Ranran Wang, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-STING p-S366 (1:1000, 19781S, Cell Signaling Technology), anti-TBK1 (1:1000 ...
• Merkel cell polyomavirus protein ALTO modulates TBK1 activity to support persistent infection

  Ranran Wang, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-IRF3 p-S386 (1:1000, 37829S, Cell Signaling Technology), anti-RFP (1:2,000 ...
• Merkel cell polyomavirus protein ALTO modulates TBK1 activity to support persistent infection

  Ranran Wang, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-Src antibody (1:1000, 2109S, Cell Signaling Technology), mouse anti-Src antibody (1:1000 ...
• Merkel cell polyomavirus protein ALTO modulates TBK1 activity to support persistent infection

  Ranran Wang, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-P65 p-S536 (1:1000, 3033S, Cell Signaling Technology), anti-IRF3 (1:500 ...
• Fes-deficient macrophages enhance CD8⁺ T cell priming and tumour control through increased proinflammatory cytokine production and presentation

  Brian J. Laight, et al., bioRxiv - Immunology 2024

  Quote: ... phospho-NF-κB (1:1000; Cell Signaling Technologies cat#: 3033S), phospho-TBK1 (1:1000 ...
• Endosomal LRBA regulates the endo-lysosomal pathway

  Viktória Szentgyörgyi, et al., bioRxiv - Immunology 2024

  Quote: ... rabbit monoclonal EEA1 (C45B10) antibody (#3288, Cell Signaling, 1:2000), rabbit monoclonal anti LAMP1 (D2D11 ...
• The interferon-ɣ inducible factor 16 (IFI16) restricts adeno-associated virus serotype 2 (AAV2) transduction in an immune-modulatory independent way

  Sereina O. Sutter, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-Rb (Cell Signaling 9309; dilution for WB; 1:2‘000), anti-Rb-P-S807/811 (Cell Signaling 8516 ...
• Nociceptive neurons interact directly with gastric cancer cells via a CGRP/Ramp1 axis to promote tumor progression

  Xiaofei Zhi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Phospho-Rb (Ser807/811, 1:200, Cell Signaling Technology), anti-NF200 (1:200 ...
• Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

  Dong Wang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and Phosphor-Pol II-Ser2 (Cell Signaling, 13499, 1:1000).
• Nuclear release of eIF1 globally increases stringency of start-codon selection to preserve mitotic arrest physiology

  Jimmy Ly, et al., bioRxiv - Molecular Biology 2024

  Quote: ... anti-phospho-eIF2α Ser51 (1:1000, Cell Signaling Technology, #3398), anti-eIF1 (1:1000 ...
• Inhibition of eukaryotic translation initiation factor 1A (eIF1A) and 3B (eIF3B) diminishes the psoriatic phenotype in two mouse models and human 3D model samples

  Nicole Golob-Schwarzl, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and Ki-67 (1:250; #12202S, Cell Signaling, Massachusetts, USA). As a secondary method ...