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801 - 850 of 10000+ citations for 7 Chloro 1 3 dihydro 1 methyl 5 phenyl 2H benzo 1 4 diazepin 2 one 4 oxide since 2019

• TRIM46 is not required for axon specification or axon initial segment formation in vivo

  Allison J. Melton, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit monoclonal antibodies against TRIM46 (#1 in text: Abcam Cat# ab307967, RRID:AB_3096363, 1:500, #2 in text: Cell Signaling Technology Cat# 92574, RRID:AB_3096364, 1:1000), guinea pig monoclonal antibody against TRIM46 (Synaptic Systems Cat# 377 308 ...
• Single-cell transcriptomic analysis unveils spinal motor neuron subtype diversity underpinning the water-to-land transition in vertebrates

  Ee Shan Liau, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-cleaved caspase-3 (1:500 Cell Signaling Cat# 9661, RRID:AB_2341188). Guinea pig anti-Foxp1 (1:320000) ...
• Revisiting the origin of interleukin 1 (IL-1) based on biological activities of IL-1 in anamniotes and their sub-functionalization in amniotes

  Eva Hasel de Carvalho, et al., bioRxiv - Immunology 2022

  Quote: ... or 1:1000 anti-cleaved Caspase-3 #9661 (rabbit, Cell Signaling Technology), followed by 1:3000 goat anti-rabbit HRP 1706515 (BioRad).
• Lipid nanoparticles delivering constitutively active STING mRNA as a novel anti-cancer therapeutic approach

  Wei Liu, et al., bioRxiv - Bioengineering 2022

  Quote: ... and anti-Cleaved Caspase-3 (Asp175) (1:500, 9661, Cell Signaling Technology). The secondary antibodies used were Alexa Fluor 594 goat anti-mouse IgG (1:500 ...
• Transcriptional and Cytotoxic Responses of Human Intestinal Organoids to Interferon Types I, II, and III

  David A. Constant, et al., bioRxiv - Immunology 2021

  Quote: ... stained with anti-cleaved caspase 3 (Cell Signaling Technology #9661S; 1:400), anti-E-cadherin (Becton Dickinson #610182 ...
• Depletion of Ric-8B leads to reduced mTORC2 activity

  Maíra H. Nagai, et al., bioRxiv - Molecular Biology 2019

  Quote: ... and anti-cleaved caspase-3 primary antibodies (Cell Signaling #9661, 1:250). Nuclei were stained with DAPI (SIGMA ...
• Multiplexed drug testing of tumor slices using a microfluidic platform

  L. F. Horowitz, et al., bioRxiv - Bioengineering 2020

  Quote: ... rabbit anti-active caspase 3 (Asp175) (1/600, Cell Signaling, Antibody #9661), mouse anti-HuNu (1/500 ...
• GCNA is a histone binding protein required for spermatogonial stem cell maintenance

  Jonathan Ribeiro, Gerry P. Crossan, bioRxiv - Physiology 2022

  Quote: ... anti-Cleaved Caspase 3 (1:300, catalog no. 9661, Cell Signaling Technology); anti-DNMT3B (1:250 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and Cleaved Caspase 3 (1:100, Cat#: 9661, Cell Signaling, Danvers, MA) overnight at 4°C ...
• Flexible Simultaneous Mesoscale Two-Photon Imaging Of Neural Activity at High Speeds

  Mitchell Clough, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-cleaved caspase-3 (Asp175) (9661; Cell Signaling; 1:250 dilution), and mouse anti-HSP70/HSP72 (C92F3A-5 ...
• RNA-binding protein Orb2 causes microcephaly and supports centrosome asymmetry in Drosophila neural stem cells

  Beverly V. Robinson, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-cleaved Caspase 3 (CC3, 1:75; Cell Signaling Technology, 9661s), mouse anti-Pros (clone MR1A ...
• The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

  Hikaru Eto, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Ring1B (Cell Signaling Technology, 5694S, 1:200, 3 μg/sample for ChIP), Cleaved caspase-3 (Cell signaling Technology ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-cleaved caspase 3 (CC3) (rabbit, 1:250) (#9664, Cell Signaling Technology), anti-FUNDC1 (rabbit ...
• Transcriptional Profiling Reveals the Transcription Factor Networks Regulating the Survival of Striatal Neurons

  Lin Yang, et al., bioRxiv - Neuroscience 2021

  Quote: ... Primary antibodies against cleaved Caspase-3 (1:500; Cell Signaling, 9661, 43) were diluted in 10% donkey serum block solution ...
• The Cardiolipin Transacylase Tafazzin Regulates Basal Insulin Secretion and Mitochondrial Function in Pancreatic Islets from Mice

  Laura K. Cole, et al., bioRxiv - Physiology 2021

  Quote: ... rabbit activated caspase 3 (1:200) (Cell Signaling Technologies, Danvers MA, USA) overnight at 4°C ...
• Human iPSC-Derived Cardiomyocytes are Susceptible to SARS-CoV-2 Infection

  Arun Sharma, et al., bioRxiv - Cell Biology 2020

  Quote: ... cleaved caspase-3 (1:200, Cell Signaling Technology Cat# 9661, RRID: AB_2341188). Samples were then rinsed 5 times for 2 minutes each with PBS containing 0.3% Triton X-100 ...
• Neonatal enthesis healing involves non-inflammatory formation of acellular scar through ECM secretion by resident cells

  Ron Carmel Vinestock, et al., bioRxiv - Molecular Biology 2021

  Quote: ... rabbit anti-cleaved caspase-3 (Asp175) antibody (1:200, #9664s, Cell Signaling) or rat anti-F4/80 antibody (1:50 ...
• Eukaryotic translation initiation factor eIF4E-5 is required for spermiogenesis in Drosophila melanogaster

  Lisa Shao, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-caspase-3 (1:400; Asp175, Cell Signaling Technology, Danvers, USA), guinea pig anti-Soti (1:100 ...
• Deficiency in Lyst function leads to accumulation of secreted proteases and predisposition to mechanic stress-induced retinal detachment

  Xiaojie Ji, et al., bioRxiv - Genetics 2021

  Quote: ... glyceraldehyde 3-phosphate dehydrogenase (GAPDH, Cell Signaling, 2118, rabbit monoclonal, 1:1000), phospho-ERM (Cell Signaling ...
• The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

  Ke Xu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-Caspase-3 antibody (1:1,000 dilution, 9662, Cell Signaling Technology), rabbit anti-Cleaved Caspase-3 monoclonal antibody (1:1,000 dilution ...
• Talin regulates steady-state tensional homeostasis to drive vascular morphodynamics and cancer

  Pinelopi Nikolopoulou, et al., bioRxiv - Cell Biology 2022

  Quote: ... Cleaved Caspase-3 (1:300 dilution, Rabbit monoclonal; Cell Signaling, Cat# 9664), PECAM (1:400 dilution ...
• Talin regulates steady-state tensional homeostasis to drive vascular morphodynamics and cancer

  Pinelopi Nikolopoulou, et al., bioRxiv - Cell Biology 2022

  Quote: ... cleaved Caspase-3 (1:100 dilution, Rabbit monoclonal; Cell Signaling, Cat# 9664), YAP (1:100 dilution ...
• Functional characterization of cardiac fibroblasts in response to hemodynamic alteration

  Manabu Shiraishi, Ken Suzuki, Atsushi Yamaguchi, bioRxiv - Molecular Biology 2022

  Quote: ... anti-cleaved caspase 3 Ab at 1:100 dilution (9661, Cell Signaling), anti-αSMA Ab at 1:00 dilution (ab5694 ...
• Soluble VE-cadherin disrupts endothelial barrier function via VE-PTP/RhoA signalling

  Juna-Lisa Knop, et al., bioRxiv - Physiology 2022

  Quote: ... cleaved caspase-3 (Asp175) antibody (WB 1:600, Cell Signaling, CatNo 9661), caspase antibody (WB 1:1000 ...
• Microdissected tumor cuboids: a microscale cancer model that retains a complex tumor microenvironment

  Lisa F Horowitz, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-human/mouse cleaved-caspase 3 (1:300; Cell Signaling, 9661). followed by 1:500 546-Donkey/Goat anti-rabbit (or other) ...
• Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury

  Mary E. Mohr, et al., bioRxiv - Cell Biology 2023

  Quote: ... Primary antibodies used include: cleaved Caspase 3 (1:200, Cell Signaling, 9664), pMLKL (1:100 ...
• Neuroprotective effects of hepatoma-derived growth factor in models of Huntington’s disease

  Kerstin Voelkl, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit anti-cleaved Caspase-3 (Cell Signaling Technology, 9661, 1:500). Cells were washed for 5 min in PBS and incubated for 30 min in the dark with Alexa Fluor 488 ...
• Primordial germ cell DNA demethylation and development require DNA translesion synthesis

  Pranay Shah, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-cleaved caspase 3 (1:400, catalog no. 9661; Cell Signaling Technology); anti-MVH (ab27591) ...
• Genetically perturbed myelin as a risk factor for neuroinflammation-driven axon degeneration

  Janos Groh, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-cleaved caspase 3 (1:300, catalog no. 9664; Cell Signaling); rabbit anti-pMLC Thr18/Ser19 (1:100 ...
• Role of the NO-GC/cGMP signaling pathway in platelet biomechanics

  Johanna G. Rodríguez, et al., bioRxiv - Biochemistry 2023

  Quote: ... glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (rabbit, 1:1000, 14C10, Cell Signaling #2118S), NO-GC (sGC β1 ...
• RhoB promotes Salmonella survival by regulating autophagy

  Marco Kirchenwitz, et al., bioRxiv - Cell Biology 2023

  Quote: ... cleaved-caspase-3 (9661, 1:1000 dilution, RRID: AB_2341188, Cell Signaling Technology), AKT (9272 ...
• MicroRNAs are necessary for the emergence of Purkinje cell identity

  Norjin Zolboot, et al., bioRxiv - Neuroscience 2023

  Quote: ... and rabbit anti-cleaved caspase-3 (1:500, Cell Signaling Technology, 9661). Secondary antibodies used were donkey anti-mouse-AF594 (Invitrogen ...
• Cancer tissue of origin constrains the growth and metabolism of metastases

  Sharanya Sivanand, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or Cleaved Caspase 3 (Asp 175) (1:400 dilution; Cell Signaling 9661). Antibodies were diluted in 10% normal goat serum diluted 1:2 (Thermo Fischer ...
• An adapted stem cell-derived microglia protocol for the study of microgliopathies and other neurological disorders

  Marie-France Dorion, et al., bioRxiv - Neuroscience 2023

  Quote: ... NLR family pyrin domain containing 3 (NLRP3; 1:500; #15101S, Cell Signaling) and GAPDH (1:5000 ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:500 Cell Signaling Technology), ERK1/2 (Thr202/Tyr204 ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... phospho-MEK1/2 (Ser217/221) (1:500 Cell Signaling Technology), MEK1/2 (1:500 Cell Signaling Technology) ...
• HDAC and MAPK/ERK Inhibitors Cooperate to Reduce Viability and Stemness in Medulloblastoma

  Mariane da Cunha Jaeger, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Phospho-p44/42 MAPK (pErk1/2, 1:2000; Cell Signaling), p44/42 MAPK (Erk1/2 ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... p-ERK1/2 T202/Y204 (#4370S, 1:1000, Cell Signaling), ERK1/2 (#4695S ...
• Extracellular Superoxide Dismutase (EC-SOD) Regulates Gene Methylation and Cardiac Fibrosis During Chronic Hypoxic Stress

  Ayan Rajgarhia, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and ERK 1/2 (Cell Signaling Technology, Danvers, MA, USA)
• Wnt-dependent activation of ERK mediates repression of chondrocyte fate during calvarial development

  Beatriz Ibarra, Cody Machen, Radhika P. Atit, bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-phospho-ERK1/2 (1:1250, Cell Signaling 4370). Wide-field images were captured at 20X and 40X using the Leica DMi8 inverted microscope using the Leica Application Suite X (LASX ...
• TrkB agonists prevent post-ischemic BDNF-TrkB mediated emergence of refractory neonatal seizures in CD-1 pups

  P.A. Kipnis, et al., bioRxiv - Neuroscience 2019

  Quote: ... rabbit α Erk1/2 (1:1000, Cell Signaling Technology; #4695), rabbit α phospho-Erk1/2 (1:1000 ...
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit anti-pErk1/2 (Cell Signaling Technology # 9101; 1:1000), Rabbit anti-Erk1/2 (Cell Signaling Technology # 9102 ...
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit anti-Erk1/2 (Cell Signaling Technology # 9102; 1:1000), Mouse anti-ß-Actin (Cell Signaling Technology # 58169 ...
• Neurofibromin 1 controls metabolic balance and Notch-dependent quiescence of juvenile myogenic progenitors

  Xiaoyan Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit anti-pErk1/2 (Cell Signaling Technology # 9101; 1:300), Rabbit anti-phosphor (s235/236)-S6 (Cell Signaling Technology # 4858 ...
• The Peroxiredoxin 6 gene plays a critical role in the homeostatic regulation of fear response

  Sarayut Phasuk, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-total ERK1/2 (1:1000; Cell Signaling, Danvers, MA), anti-PSD95 (1:2000 ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p44/42 MAPK (Erk1/2) (Cell Signaling, 9102s, 1:1000), MITF (Cell Signaling ...
• Hemangiosarcoma cells induce M2 polarization and PD-L1 expression in macrophages

  Kevin Christian M. Gulay, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-ERK1/2 antibody (1:1000; Cell Signaling Technology, 4695S), anti-H2AK119Ub1 antibody (1:2000 ...
• A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes corpus luteum regression

  Dianrong Li, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Phospho-MEK1/2 (9154S, Cell Signaling; WB, 1:1000), anti-MEK1/2 (ab178876 ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and pLATS1/2 (1:500, Cell Signaling Technology, #8654, RRID:AB_10971635) and Cytochrome P450 2E1 (1:500 ...
• Vitamin C functions as double-edge sword on cancer progression depending on ERK activation or inhibition mediated by its receptor SVCT2

  Yian Guan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-pERK1/2 (1:5000, Cat#9101, Cell Signaling Technology), anti-PTPN12 (1:500 ...