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801 - 850 of 1122 citations for 6 Amino benzooxazole 2 thiol since 2019

• Cell-intrinsic functions of the transcription factor Bhlhe40 in activated B cells and T follicular helper cells restrain the germinal center reaction and prevent lymphomagenesis

  René Rauschmeier, et al., bioRxiv - Immunology 2021

  Quote: ... Alexa Fluor 647–labeled anti–rabbit F(ab)2 fragment (both from Cell Signaling Technology) and the Cytofix/Cytoperm kit (BD ...
• Differentiation signals from glia are fine-tuned to set neuronal numbers during development

  Anadika R. Prasad, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (1:100, Cell Signaling #9101), chicken anti-RFP (1:500 ...
• Discovery of E6AP AZUL binding to UBQLN1/2 in cells, phase-separated droplets, and an AlphaFold-NMR integrated structure

  Gwen R. Buel, et al., bioRxiv - Biophysics 2022

  Quote: ... 2 mg of protein was combined with 15 µL anti-UBQLN1 (Cell Signaling Technologies 14526) or anti-UBQLN2 (Cell Signaling Technologies 85509 ...
• HD-PTP/PTPN23 hypomorphic mice display lipodystrophy

  Brian A. Davies, et al., bioRxiv - Cell Biology 2022

  Quote: ... total-p42/44 MAPK (ERK1/2) 3A7 mouse monoclonal antibody (1:2000, 9107, Cell Signaling), p-AKT-S473 D9E rabbit monoclonal antibody (1:1000 ...
• Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates that reduce surface AMPA receptor expression in primary neurons

  Jocelyn Widagdo, et al., bioRxiv - Neuroscience 2022

  Quote: ... total myc-GluA1/2 was labeled with rabbit anti-myc antibody (71D10, Cell Signaling Technology) at 4°C overnight ...
• Murine gammaherpesvirus 68 ORF45 stimulates B2 retrotransposon and pre-tRNA activation in a manner dependent on mitogen-activated protein kinase (MAPK) signaling

  Azra Lari, Britt A. Glaunsinger, bioRxiv - Microbiology 2022

  Quote: ... anti-phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) antibody (Cell Signaling #9101, 1:1000), anti-Brf1polyclonal antibody (Bethyl ...
• Thrombospondin 2 is a key determinant of fibrogenesis in NAFLD

  Takefumi Kimura, et al., bioRxiv - Molecular Biology 2023

  Quote: ... small mothers against decapentaplegic (SMAD) 2/3 (D7/G7) (Cell Signaling Technology, #8685, 1:1,000), Phospho-Smad2 (Ser465/467)/Smad3 (Ser423/425 ...
• Drugs of abuse hijack a mesolimbic pathway that processes homeostatic need

  Bowen Tan, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2% donkey serum) and then incubated with primary antibody (rabbit anti-c-fos, Cell Signaling, 1:500 for 100-μm sections ...
• Atypical Chemokine Receptor 3 ‘Senses’ CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation

  Christopher T. Schafer, et al., bioRxiv - Biochemistry 2023

  Quote: ... ERK1/2 phosphorylation was detected by probing with anti-phospho-p44/42 (4370, Cell Signaling) and anti-tubulin (T6074 ...
• Combined KRAS^G12C and SOS1 inhibition enhances and extends the anti-tumor response in KRAS^G12C-driven cancers by addressing intrinsic and acquired resistance

  Venu Thatikonda, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (1:2000, Cell Signaling Technology #4370) was developed using Opal tyramide signal amplification (TSA ...
• Oncogenic Kras^G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8⁺ T cells dependent manner

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (1:2000, Cell Signaling Technology #4370) was developed using Opal tyramide signal amplification (TSA ...
• Control of gastruloid patterning and morphogenesis by the Erk and Akt signaling pathways

  Evan J. Underhill, Jared E. Toettcher, bioRxiv - Developmental Biology 2023

  Quote: ... Erk1/2 phosphorylated at Thr202 and Tyr204 rabbit (Cell Signaling Technology, 4370, 1:200 dilution), phospho-Akt at Ser473 rabbit (Cell Signaling Technology ...
• Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis

  Thomas Kehrer, et al., bioRxiv - Microbiology 2022

  Quote: ... Antibodies used for immunostaining of histology slides are: SARS-CoV-2 spike (99423S, Cell Signaling) at a 1:400 dilution ...
• Alterations in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers revealed by spatial transcriptomics

  Anthony Caputo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 1:200 phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling Technology, 9101S). Primary antibodies used for immunohistochemistry of FFPE tissues were 1:50 COL6 (Rockland ...
• Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)

  Ting Zhang, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... or 2 μg control normal Rabbit IgG antibody (antibody 2729; Cell Signaling Technology, Danvers, MA), in the presence of protein G magnetic beads ...
• FGF9, a potent mitogen, is a new ligand for integrin αvβ3, and the FGF9 mutant defective in integrin binding acts as an antagonist

  Chih-Chieh Chang, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-phospho-p44/42 MAPK (p-ERK1/2) (Thr-202/Tyr204) (Cell Signaling Technology, USA), rabbit anti-FGFR1 (Cell Signaling Technology ...
• Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral and signaling plasticity in vivo

  Mohamed R. Ahmed, et al., bioRxiv - Neuroscience 2023

  Quote: ... blots were re-probed with a rabbit anti-ERK1/2 antibody (Cell Signaling, cat.# 9102) at 1:1,000 dilution to detect total ERK1/2 ...
• Hyperactivation of MEK1 in cortical glutamatergic neurons results in projection axon deficits and aberrant motor learning

  George R. Bjorklund, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (RRID:AB_2315112, Cell Signaling Technologies 4370), rabbit anti-ERK2 (RRID:AB_732210 ...
• Hyperactivation of MEK1 in cortical glutamatergic neurons results in projection axon deficits and aberrant motor learning

  George R. Bjorklund, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) (RRID:AB_2315112, Cell Signaling Technologies 4370), rabbit anti-ERK2 (RRID:AB_732210 ...
• Influence of myosin regulatory light chain and myosin light chain kinase on hair cells of the inner ear

  Ryohei Oya, et al., bioRxiv - Biophysics 2023

  Quote: ... anti-phospho-myosin light chain 2 (3671; Cell Signaling Technology, Danvers, MA, USA; 1:50); Alexa Fluor 488-labeled secondary antibody (Thermo Fisher Scientific ...
• Endosomal LRBA regulates the endo-lysosomal pathway

  Viktória Szentgyörgyi, et al., bioRxiv - Immunology 2024

  Quote: ... mouse monoclonal anti p44/42 MAPK (Erk1/2) (L334F10) antibody (#4696, Cell Signaling, 1:2000), rabbit polyclonal anti phospho-p44/42 MAPK (Erk1/2 ...
• Endosomal LRBA regulates the endo-lysosomal pathway

  Viktória Szentgyörgyi, et al., bioRxiv - Immunology 2024

  Quote: ... mouse monoclonal anti p44/42 MAPK (Erk1/2) (L334F10) antibody (#4696, Cell Signaling, 1:2000), rabbit polyclonal anti phospho-p44/42 MAPK (Erk1/2 ...
• Enhanced feature matching in single-cell proteomics characterizes response to IFN-γ and reveals co-existence of different cell states

  Karl K. Krull, Syed A. Ali, Jeroen Krijgsveld, bioRxiv - Systems Biology 2024

  Quote: ... U-2 OS cells underwent treatment with 50 ng/mL recombinant IFN-γ (Cell Signaling). The cytokine was diluted in 0.5% (w/v ...
• Ca²⁺-driven cytoplasmic backflow secures spindle position in fertilized mouse eggs

  Takaya Totsuka, Miho Ohsugi, bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-phospho-myosin light chain 2 (Ser19) (pMLC) (1:100, Cell Signaling Technology #3671), for 2 hours ...
• Mechanoaccumulation of non-muscle myosin IIB during mitosis requires its translocation activity

  Chao Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... or the GFP antibody (HuaBio, ET1604-26; used in Figs. 5 B C D and 6 A) or GAPDH antibody (Cell Signaling Technology, #5174; used in Fig. S3 A) or p-MLC2 antibody (Cell Signaling Technology ...
• ERK-mediated mechanochemical waves direct collective cell polarization

  Naoya Hino, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-phospho-MEK1/2 (Ser217/221) rabbit antibody (no. 9121, Cell Signaling Technology, 1:1,000 dilution); anti-ERK1/2 mouse antibody (no ...
• Active Perception during Angiogenesis: Filopodia speed up Notch selection of tip cells in silico and in vivo

  Bahti Zakirov, et al., bioRxiv - Cell Biology 2020

  Quote: ... Embryos were subsequently incubated overnight with anti-phospho-ERK1 /2 antibody (1:250, Cell Signaling; #4370) in blocking buffer ...
• Tumor Suppressor p53 Restrains Cancer Cell Dissemination by Modulating Mitochondrial Dynamics

  Thi Tuyet Trinh Phan, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and phospho-ERK1/2 (Thr202/Tyr204) (4370) were purchase from Cell Signaling Technology (Beverly, MA, USA). Antibodies against MTFP1 (ab198217 ...
• IDENTIFICATION OF A NOVEL BDNF-SPECIFIC CORTICOSTRIATAL CIRCUITRY

  Yann Ehinger, et al., bioRxiv - Neuroscience 2021

  Quote: ... Rabbit anti-Phospho-ERK1/2 antibody (CST 4377) was purchased from Cell Signaling Technology (Danvers, MA). Chicken anti-GFP (A10262) ...
• Nintedanib ameliorates experimental pulmonary arterial hypertension via inhibition of endothelial mesenchymal transition and smooth muscle cell proliferation

  Takeo Tsutsumi, et al., bioRxiv - Physiology 2019

  Quote: ... anti-Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) Antibody (1:2,000; #9101, Cell Signaling Technology), anti-AKT polyclonal antibody (1:2,000 ...
• MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

  Junmei Cairns, et al., bioRxiv - Cancer Biology 2019

  Quote: ... p-MEK1/2 and Phospho-(Ser) PKC Substrate Antibody were purchased from Cell Signaling (Danvers, MA). ERα and ERα-S167 antibodies were obtained from Abcam (Cambridge ...
• ASH2L drives proliferation and sensitivity to bleomycin and other genotoxins in Hodgkin’s lymphoma and testicular cancer cells

  Daniel Constantin, Christian Widmann, bioRxiv - Cancer Biology 2020

  Quote: ... lot 2) and the one used for immunocytochemistry was from Cell Signaling (CLS D93F6; lot 1). The antibodies against H3K4me3 (Ab8580 ...
• Nanchangmycin regulates FYN, FAK and ERK to control the fibrotic activity of hepatic stellate cells

  Wenyang Li, et al., bioRxiv - Cell Biology 2021

  Quote: ... phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) antibody (1:1000, Cell Signaling Technology, cat# 4370), and goat anti-rabbit IgG secondary antibody (Invitrogen ...
• Dampened PI3K/AKT signaling contributes to cancer resistance of the naked mole rat

  Jing Zhao, et al., bioRxiv - Cancer Biology 2020

  Quote: The following antibodies were used in this study: phospho-ERK1/2 (4370, Cell Signaling Technology (CST)) ...
• Silencing of oncogenic KRAS by mutant-selective small interfering RNA

  Bjoern Papke, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Rabbit polyclonal anti-phospho-p44/42 MAPK (pERK1/2) (Thr202/Tyr204) (Cell Signaling Technology Cat #4370), Rabbit polyclonal anti-p44/42 MAPK (ERK1/2 ...
• Dynamics and heterogeneity of Erk-induced immediate-early gene expression

  Siddhartha G. Jena, et al., bioRxiv - Cell Biology 2021

  Quote: ... Primary antibodies used were Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling Technology #9101), c-Fos (Cell Signaling Technology #2250) ...
• Optimized Workflow for Enrichment and Identification of Biotinylated Peptides using Tamavidin 2-REV for BioID and Cell Surface Proteomics

  Kohei Nishino, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-phospho-ERK1/2 (Thr202/Tyr204) (D13.14.4E) XP rabbit mAb (Cell Signaling Technology, #4370, 1:2,500); anti-α-tubulin (DM1a ...
• A dual mechanism of APC/C inhibition by MAP kinases

  Li Sun, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit polyclonal anti-phospho-p44/42 (detecting activated Pmk1 or Erk1/2) (Cell Signaling Technology; #9101); rabbit polyclonal anti-PSTAIRE (detecting Cdc2 ...
• Purinergic receptor P2RY14 cAMP signaling regulates EGFR-driven Schwann cell precursor self-renewal and nerve tumor initiation in neurofibromatosis

  Jennifer Patritti-Cram, et al., bioRxiv - Neuroscience 2021

  Quote: ... phosphor-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) rabbit (1:1000, Cell Signaling Technologies, Cat#: 8544S); P44/42 MAPK (Erk1/2 ...
• Towards a biotechnological platform for the production of human pro-angiogenic growth factors in the green alga Chlamydomonas reinhardtii

  Montserrat Jarquín-Cordero, et al., bioRxiv - Plant Biology 2019

  Quote: ... The primary monoclonal antibodies rabbit mAb anti-VEGFR-2 (55B11) (Cell Signaling Technology, Danvers, MA, USA) and rabbit mAb anti-phospho-VEGFR-2 (Tyr1175 ...
• Existence and functions of hypothalamic kisspeptin neuropeptide signaling system in a non-chordate deuterostome species

  Tianming Wang, et al., bioRxiv - Evolutionary Biology 2019

  Quote: ... then probed with rabbit anti-phospho-RK1/2(Thr202/Tyr204) antibody (1:2,000; Cell Signaling Technology), followed by detection using HRP-conjugated goat anti-rabbit IgG (Beyotime) ...
• Existence and functions of hypothalamic kisspeptin neuropeptide signaling system in a non-chordate deuterostome species

  Tianming Wang, et al., bioRxiv - Evolutionary Biology 2019

  Quote: ... Blots were stripped and reprobed by using anti-ERK1/2 antibody (1:2,000; Cell Signaling Technology), as a control for protein loading.
• Genome-wide analysis of transcriptional bursting-induced noise in mammalian cells

  Hiroshi Ochiai, et al., bioRxiv - Systems Biology 2019

  Quote: ... anti-Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (1:2000; 4370, Cell Signaling Technology, RRID:AB_2315112), anti-Phospho-4E-BP1 (Thr37/46 ...
• Spatial integration of mechanical forces by alpha-actinin establishes actin network symmetry

  Fabrice Senger, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-phospho myosin light chain 2 (Ser19) (Cell Signaling Technology #3671; 1/50 for Iimmunofluorescence), rabbit anti-ACTN1 (Sigma #HPA006035 ...
• Mechanochemical control of epidermal stem cell divisions by B-plexins

  Chen Jiang, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit polyclonal anti-phospho-myosin light chain 2 (Ser19) (1:200, Cell Signaling, cat. no. #3671), rabbit polyclonal anti-phospho-myosin light chain 2 (Thr18/Ser19 ...
• Targeting G_i/o protein-coupled receptor signaling blocks HER2-induced breast cancer development and enhances HER2-targeted therapy

  Cancan Lyu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (no. 4696) and phospho-ERK1/2T202/Y204 (no. 4370) were from Cell Signaling Technology; GADPH (sc-47724 ...
• RIOK2 drives glioblastoma cell proliferation by modulating MYC through the RNA-binding protein IMP3

  Alexander S. Chen, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Beads were conjugated with 10 μg either anti-IMP3 (#1: MBL, RN009P, #2: Cell Signaling, 57145) or non-specific IgG ...
• Rac1, Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons

  Zouzana Kounoupa, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse monoclonal anti-Phospho-Myosin light chain 2 (Ser19) (1:200; Cell signaling, Beverly, MA, USA), anti-mouse Phospho RhoA ...
• Independent control over cell patterning and adhesion on hydrogel substrates for tissue interface mechanobiology

  Louis S. Prahl, et al., bioRxiv - Bioengineering 2022

  Quote: ... rabbit anti-phospho-p44/42 MAPK (ERK1/2) (1:200, #4370, Cell Signaling Technologies, RRID: AB_2315112), and rabbit anti-E-cadherin (24E10 ...
• ROS induction as a strategy to target persister cancer cells with low metabolic activity in NRAS mutated melanoma

  Ossia M. Eichhoff, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204, 20G11, Cell Signaling #4376, RRID:AB_331772, dilution 1:1000), Caveolin-1 (E249 ...