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801 - 850 of 10000+ citations for 5 Methoxy 1 Triisopropylsilyl 1H Pyrrolo 2 3 B Pyridine since 2020

• miR-17∼92 exerts stage-specific effects in adult V-SVZ neural stem cell lineages

  Fabrizio Favaloro, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-cleaved caspase 3 (rabbit polyclonal, 1:100, Cell Signaling, Cat# 9661, RRID: AB_2341188); anti-DLX2 (mouse polyclonal ...
• The early endosomal protein Rab21 is critical for enterocyte functions and intestinal homeostasis

  Sonya Nassari, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-cleaved caspase 3 (#9661, Cell Signaling Technology, Danvers, MA, USA; 1/500), rabbit anti-ref(2)p (ab178440 ...
• eyes absent in the cockroach panoistic ovaries regulates proliferation and differentiation through ecdysone signalling

  S. Ramos, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit antibody anti-cleaved Caspase-3 (Asp-175, Cell Signaling Tech; dilution 1:50), and mouse antibody anti-Eya ...
• FLASH irradiation enhances the therapeutic index of abdominal radiotherapy for the treatment of ovarian cancer

  Karen Levy, et al., bioRxiv - Cancer Biology 2020

  Quote: ... sections were incubated in cleaved caspase-3 (Asp175) antibody (1:300; Cell Signaling Technology) at 4°C overnight in a humidified chamber ...
• PFKFB3 Depletion Activates β-Cell Replication by Cell Competitive Culling of Compromised β-Cells Under Stress

  Jie Min, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-cleaved caspase-3 (Cell Signaling Technology 9664S, Danvers, MA, USA, 1:400); ...
• The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

  Ke Xu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-Cleaved Caspase-3 monoclonal antibody (1:1,000 dilution, 9664, Cell Signaling Technology), rabbit anti-B-cell lymphoma-2 (BCL-2 ...
• Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner

  Aleksandra Janusz-Kamińska, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-caspase 3 antibody (Cell Signaling, catalog no. 9662; 1:1000 for WB), rabbit anti-phospho-GluA1 (Ser845 ...
• Targeting tumour-intrinsic neural vulnerabilities of glioblastoma

  Sohyon Lee, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Alexa Fluor® 555 anti-Cleaved Caspase-3 (1:500, Cell Signaling Technology, #9604S), Alexa Fluor® 546 anti-HOMER (1:300 ...
• The efficacy of CB-103, a first-in-class transcriptional Notch inhibitor, in preclinical models of breast cancer

  Michele Vigolo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and a rabbit polyclonal anti-Cleaved Caspase 3 (Cell Signaling, Asp175, 1:500 dilution). After rinsing in PBS ...
• ATF4 Dependent Increase in Mitochondrial-Endoplasmic Reticulum Tethering Following OPA1 Deletion in Skeletal Muscle

  Antentor Hinton Jr., et al., bioRxiv - Biophysics 2023

  Quote: ... glyceraldehyde 3-phosphate dehydrogenase (GAPDH; 1:5,000; Cell Signaling Technology: Danvers, MA, USA; #2118), MFN1 (1:1,000 ...
• An shRNA screen in primary human beta cells identifies the serotonin 1F receptor as a negative regulator of survival during transplant

  Rebecca A. Lee, et al., bioRxiv - Cell Biology 2024

  Quote: ... The primary antibodies were rabbit anti-cleaved caspase-3 (Cell Signaling; 9661; 1:100), chicken anti-GFP (Aves Labs ...
• Cyclin A/B RxL Macrocyclic Inhibitors to Treat Cancers with High E2F Activity

  Shilpa Singh, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The primary antibodies were: rabbit anti-Histone 3 DH12 (Cell Signaling #4499, 1:5000) and rabbit anti-phospho Histone H2A.X Ser 139 (Cell signaling #2577 ...
• NMNAT promotes glioma growth through regulating post-translational modifications of p53 to inhibit apoptosis

  Jiaqi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti- Caspase-3 (1:250 for Immunocytochemistry of fly brain, 1:1000 for Western blot analysis, Cell Signaling, 9665), anti-Cleaved Caspase-3 (1:1000 ...
• Trp53 ablation fails to prevent microcephaly in mouse pallium with impaired minor intron splicing

  Alisa K. White, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 1:200 (mouse anti-γH2AX, MilliporeSigma, 05-636; or 1:300 (rabbit anti-cleaved caspase 3, Cell Signaling Technology, 9665S ...
• Intermittent KHz-frequency electrical stimulation selectively engages small unmyelinated vagal afferents

  Yao-Chuan Chang, et al., bioRxiv - Bioengineering 2022

  Quote: ... were washed with TBS buffer 3 times for 5 minutes and subjected to antigen retrieval using 1X SignalStain® Citrate Unmasking Solution (Cell signaling). The citrate buffer was bought to boiling temperature and added to the sections ...
• Short-term high fat diet feeding of mice suppresses catecholamine-stimulated Ca²⁺ signalling in hepatocytes and intact liver

  Robert P. Brumer, et al., bioRxiv - Physiology 2022

  Quote: ... The following day sections were washed in wash buffer 3 times for 5 min and co-stained for anti-Rabbit IgG Fab2 Alexa Fluor 488 (Cell Signaling, 4412S) at 1:1000 dilution at room temperature for 1 h ...
• Altered PVN-to-CA2 hippocampal oxytocin pathway and reduced number of oxytocin-receptor expressing astrocytes in heart failure rats

  Ferdinand Althammer, et al., bioRxiv - Neuroscience 2022

  Quote: ... Membranes were then washed in TBS-T (3 × 5 min) and probed with secondary antibodies: mouse (Cat #: 7076S; Cell Signaling Danvers, MA) or rabbit (Cat # ...
• Cocaine, via ΔFosB, remodels gene expression and excitability in ventral hippocampus

  Andrew L. Eagle, et al., bioRxiv - Neuroscience 2024

  Quote: ... Immunoprecipitation was carried out overnight at 4 °C using 5 μl of rabbit polyclonal FosB antibody (2251S, lot 3, Cell Signaling Technology) or 2 μg of rabbit polyclonal IgG isotype (3900S ...
• Sensitivity to Vγ9Vδ2TCR T cells is imprinted after single mutations during early oncogenesis

  Astrid Cleven, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit mAb P44/42 MAPK (Erk 1/2) (137F5) (1:1,000; #4695; Cell Signaling Technology), rabbit mAb Phospho-MAPK (Erk 1/2 Thr202/Tyr204 ...
• Optical TrkB activation in Parvalbumin interneurons regulates intrinsic states to orchestrate cortical plasticity

  Frederike Winkel, et al., bioRxiv - Neuroscience 2020

  Quote: ... blocked in TBST with 3% BSA for 1 hour at room temperature and incubated in primary antibody solutions (in TBST with 3% BSA) directed against: phosphorylated (pY816, #4168, 1:1000; pY515, #9141, 1:1000; pY706-7, #4621S, 1:1000, Cell signaling technology (CST), Danvers ...
• Malignant astrocyte swelling and impaired glutamate clearance drive the expansion of injurious spreading depolarization foci

  Ákos Menyhárt, et al., bioRxiv - Neuroscience 2020

  Quote: ... then blocked with 3 % BSA in PBS for 1 h at room temperature and incubated with primary antibodies (mouse anti-GFAP, Sigma, 1:500; mouse anti-NeuN, Millipore, 1:500; rabbit anti-cleaved caspase-3, Cell Signaling, 1:500) overnight in 3 % BSA in PBS at 4°C ...
• O-glycosylation regulates plant developmental transitions downstream of miR156

  Krishna Vasant Mutanwad, et al., bioRxiv - Plant Biology 2021

  Quote: ... or blocked with 5% BSA for 1 hour at room temperature and probed with anti-HA antibody (rabbit, Cell Signaling Technology 3742S, 1:1000 in 5% BSA/PBST) respectively ...
• Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation

  Qin Ni, et al., bioRxiv - Biophysics 2024

  Quote: ... cells were washed 3X in PBS and blocked for 1 h at RT with 5% BSA solution containing 5% normal goat serum (Cell Signaling) and 0.1% Triton X-100 ...
• The homeodomain transcription factor Ventx2 regulates respiratory progenitor cell number and differentiation timing during Xenopus lung development

  Scott A. Rankin, Aaron M. Zorn, bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-phosopho-Smad1/5/9 (Cell Signaling Technology #13820, 1:500); chicken anti-GFP (Aves Labs GFP-1020 ...
• Programmable downsizing of CRISPR-Cas9 activity for precise and safe genome editing

  Masaki Kawamata, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and rabbit monoclonal pSmad1/5/8 (D5B10, Cell Signaling Technology, 1:1000) antibodies were reacted overnight at 4 °C ...
• Colon Cancer Cells Evade Drug Action by Enhancing Drug Metabolism

  Bojie Cong, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HRP-linked antibody (1:2000 in 5%BSA/TBST, #7076S, Cell Signaling), anti-rabbit IgG ...
• Mmp17-deficient mice exhibit heightened goblet cell effector expression in the colon and increased resistance to chronic Trichuris muris infection

  Pia M. Vornewald, et al., bioRxiv - Immunology 2023

  Quote: ... pStat6 (Cell Signaling Technology 56554S, 1:1000 5% BSA and TBS-T), and GAPDH (Abcam ab125247 ...
• Collagen receptor GPVI-mediated platelet activation and pro-coagulant activity aggravates inflammation and aortic wall remodelling in abdominal aortic aneurysm

  T Feige, et al., bioRxiv - Cell Biology 2023

  Quote: ... Respective IgG antibodies served as negative control (#3900S, Cell Signaling, 1:5). For visualizing nuclei ...
• Extracellular vesicles adhere to cells predominantly through the interaction of CD151-associated integrin heterodimers and GM1 with laminin

  Tatsuki Isogai, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit polyclonal anti-integrin beta 5 (1:500, Cell Signaling, Cat# 4708S), rabbit polyclonal anti-laminin 1+2 (1:1000 ...
• Extracellular vesicles adhere to cells predominantly through the interaction of CD151-associated integrin heterodimers and GM1 with laminin

  Tatsuki Isogai, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit polyclonal anti-integrin alpha 5 (1:250, Cell Signaling, Cat# 4705S), rabbit polyclonal anti-integrin alpha 6 (1:500 ...
• Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis

  Sachin N. Davis, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-phospho-Smad1/5 (1:800, 9516, Cell Signaling Technology, RRID:AB_491015), rabbit anti-Ki67 (0.5 µg/ml ...
• High-throughput diversification of protein-ligand surfaces to discover chemical inducers of proximity

  James B. Shaum, et al., bioRxiv - Biochemistry 2024

  Quote: ... or GAPDH (Cell Signaling Technologies, 1:1000 in 5% milk in TBST). Membranes were washed followed by incubation with the secondary IRDye 800CW donkey anti-rabbit antibody (Thermo Fisher Scientific ...
• The VGCC auxiliary subunit α2δ1 is an extracellular GluA1 interactor and regulates LTP, spatial memory, and seizure susceptibility

  Gerardo Leana-Sandoval, et al., bioRxiv - Neuroscience 2024

  Quote: ... After blocking tissue with 5% swine serum (Jackson Immuno Research, # 014-000-121) and 2% BSA (Cell Signaling, #9998S) in permeabilizing conditions (0.1% Triton X-100 ...
• Ubiquitin specific protease 1 expression and function in T cell immunity

  Kyla D Omilusik, et al., bioRxiv - Immunology 2021

  Quote: ... Id2 (1:1000; 9-2-8, CalBioeagents or D39E8, Cell Signaling), Id3 (1:1000 ...
• Dopamine ameliorates hyperglycemic memory-induced vascular dysfunction in diabetic retinopathy

  Yeon-Ju Lee, et al., bioRxiv - Biochemistry 2022

  Quote: ... Bcl-2-associated X protein (BAX) (1:1000, Cell Signaling Technology), cytochrome c (1:500 ...
• Metabolic Derangement in Polycystic Kidney Disease Mouse Models Is Ameliorated by Mitochondrial-Targeted Antioxidants

  Nastaran Daneshgar, et al., bioRxiv - Pathology 2021

  Quote: ... p44/42 MAPK (Erk1/2) (Cell Signaling Technology, 4695, 1:500) and phospho-p44/42 MAPK (ERK1/2 ...
• PDGFR dimer-specific activation, trafficking and downstream signaling dynamics

  Madison A. Rogers, Katherine A. Fantauzzo, bioRxiv - Cell Biology 2021

  Quote: ... phospho-Erk1/2 (1:1000; Thr202/Thr204; 9101; Cell Signaling Technology); Erk1/2 (1:1000 ...
• Computational pharmacogenomics screen identifies synergistic statin-compound combinations as anti-breast cancer therapies

  Jenna van Leeuwen, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p44/42 MAPK (ERK1/2) (1:1000, Cell Signaling Technology, 4695), PARP (1:1000 ...
• Hemangiosarcoma cells induce M2 polarization and PD-L1 expression in macrophages

  Kevin Christian M. Gulay, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p-ERK1/2 antibody (1:1000; Cell Signaling Technology, 4370S), anti-ERK1/2 antibody (1:1000 ...
• Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

  Parishmita Sarma, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-pERK1/2 (1:5000; Cell Signaling Technology, Cat. no. 9101), and anti-tERK1/2 (1:5000 ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and anti-pLATS1/2 (1:200, Cell Signaling Technology, #8654, RRID:AB_10971635). Subsequently ...
• GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

  Christina Wolf, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-PKM1/2 mAb (clone C103A3, 1:1000, Cell Signaling 3582), anti-TOM20 (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... phospho-ERK1/2 (1:1000, Cat#: 4377, Cell Signaling, Danvers, MA), total ERK1/2 (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... total ERK1/2 (1:1000, Cat#: 9102, Cell Signaling, Danvers, MA), phospho-JNK (1:1000 ...
• Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome

  Fikri Birey, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Myosin Light Chain 2 (rabbit, 1:1,000, Cell Signaling, 8505S), and Phospho-Myosin Light Chain 2 (Ser19 ...
• Angiocrine IGFBP3 Spatially Coordinates IGF Signaling During Neonatal Cardiac Regeneration

  Shah R. Ali, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-p44/42 MAPK (Erk1/2) (Cell Signaling, 9102S, 1:500), anti-phospho p44/42 MAPK (Erk1/2 ...
• Targeting of MCL-1 in breast cancer associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties

  TL Bonneaud, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 2 μl of anti-MCL-1 antibody (Cell signaling mAb #94296) and 10μl of beads were then used for 200 μg of proteins following manufacturer’s instructions (direct protocol) ...
• Endothelial cell polarity and extracellular matrix production rely on functional ATP6AP2 during developmental and pathological angiogenesis

  NR Patel, A Blanks, Y Li, MC Prieto, SM Meadows, bioRxiv - Molecular Biology 2021

  Quote: ... anti-p44/42 MAPK (Erk1/2) (Cell signaling, 4695, 1:1000), anti-phospho-p44/42 MAPK (pErk1/2 ...
• Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor

  Jie Li, Jiayi Wu, Xiao-chen Bai, Eunhee Choi, bioRxiv - Cell Biology 2022

  Quote: ... anti-pERK1/2 (WB, 1:000; 197G2, Cat. #4377, Cell Signaling); anti-IR (WB ...
• In vivo KRAS G12D/V degradation mediated by CANDDY using a modified proteasome inhibitor

  Satoshi Imanishi, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... Erk1/2 (p44/42 MAPK) (1:1000, #4695; Cell Signaling Technology), p-Akt (1:2000 ...