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751 - 800 of 10000+ citations for Acetamide N 2 3 dihydro 2 3 hydroxy 2 quinolinyl 1 3 dioxo 1H inden 5 yl since 2020

• BAX is necessary for neuronal death following exposure to isoflurane during the neonatal period

  Andrew M. Slupe, Laura Villasana, Kevin M. Wright, bioRxiv - Neuroscience 2020

  Quote: ... followed by antibody staining with 1:1000 anti-cleaved caspase-3 (Cell Signaling Technology) and subsequently 1:1000 anti-rabbit Alexa 568 (ThermoFisher ...
• EMC is required for biogenesis and membrane insertion of Xport-A, an essential chaperone of rhodopsin-1 and the TRP channel

  Catarina J. Gaspar, et al., bioRxiv - Cell Biology 2021

  Quote: ... testis were incubated with rabbit anti-cleaved caspase 3 (1:200) (Asp175, Cell Signaling) diluted in 0.1% PBT ...
• Cancer cells induce hepatocytes apoptosis in co-opted colorectal cancer liver metastatic lesions

  Miran Rada, et al., bioRxiv - Cancer Biology 2021

  Quote: The following primary antibodies were used: cleaved caspase-3 1:100 (Cell signaling, # 9664S) and cleaved PARP-1 1:50 (Cell signaling ...
• String/Cdc25 phosphatase is a suppressor of Tau-associated neurodegeneration

  Andreia C. Oliveira, et al., bioRxiv - Neuroscience 2022

  Quote: ... Incubation with primary antibodies anti-Cleaved caspase 3 (Asp 175) (1:50, Cell Signaling) and anti-ELAV (1:400 ...
• miR-17∼92 exerts stage-specific effects in adult V-SVZ neural stem cell lineages

  Fabrizio Favaloro, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-cleaved caspase 3 (rabbit polyclonal, 1:100, Cell Signaling, Cat# 9661, RRID: AB_2341188); anti-DLX2 (mouse polyclonal ...
• The early endosomal protein Rab21 is critical for enterocyte functions and intestinal homeostasis

  Sonya Nassari, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-cleaved caspase 3 (#9661, Cell Signaling Technology, Danvers, MA, USA; 1/500), rabbit anti-ref(2)p (ab178440 ...
• eyes absent in the cockroach panoistic ovaries regulates proliferation and differentiation through ecdysone signalling

  S. Ramos, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit antibody anti-cleaved Caspase-3 (Asp-175, Cell Signaling Tech; dilution 1:50), and mouse antibody anti-Eya ...
• FLASH irradiation enhances the therapeutic index of abdominal radiotherapy for the treatment of ovarian cancer

  Karen Levy, et al., bioRxiv - Cancer Biology 2020

  Quote: ... sections were incubated in cleaved caspase-3 (Asp175) antibody (1:300; Cell Signaling Technology) at 4°C overnight in a humidified chamber ...
• PFKFB3 Depletion Activates β-Cell Replication by Cell Competitive Culling of Compromised β-Cells Under Stress

  Jie Min, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-cleaved caspase-3 (Cell Signaling Technology 9664S, Danvers, MA, USA, 1:400); ...
• The efficacy of CB-103, a first-in-class transcriptional Notch inhibitor, in preclinical models of breast cancer

  Michele Vigolo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and a rabbit polyclonal anti-Cleaved Caspase 3 (Cell Signaling, Asp175, 1:500 dilution). After rinsing in PBS ...
• Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner

  Aleksandra Janusz-Kamińska, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-caspase 3 antibody (Cell Signaling, catalog no. 9662; 1:1000 for WB), rabbit anti-phospho-GluA1 (Ser845 ...
• Targeting tumour-intrinsic neural vulnerabilities of glioblastoma

  Sohyon Lee, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Alexa Fluor® 555 anti-Cleaved Caspase-3 (1:500, Cell Signaling Technology, #9604S), Alexa Fluor® 546 anti-HOMER (1:300 ...
• ATF4 Dependent Increase in Mitochondrial-Endoplasmic Reticulum Tethering Following OPA1 Deletion in Skeletal Muscle

  Antentor Hinton Jr., et al., bioRxiv - Biophysics 2023

  Quote: ... glyceraldehyde 3-phosphate dehydrogenase (GAPDH; 1:5,000; Cell Signaling Technology: Danvers, MA, USA; #2118), MFN1 (1:1,000 ...
• The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

  Ke Xu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... rabbit anti-Cleaved Caspase-3 monoclonal antibody (1:1,000 dilution, 9664, Cell Signaling Technology), rabbit anti-B-cell lymphoma-2 (BCL-2 ...
• An shRNA screen in primary human beta cells identifies the serotonin 1F receptor as a negative regulator of survival during transplant

  Rebecca A. Lee, et al., bioRxiv - Cell Biology 2024

  Quote: ... The primary antibodies were rabbit anti-cleaved caspase-3 (Cell Signaling; 9661; 1:100), chicken anti-GFP (Aves Labs ...
• Cyclin A/B RxL Macrocyclic Inhibitors to Treat Cancers with High E2F Activity

  Shilpa Singh, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The primary antibodies were: rabbit anti-Histone 3 DH12 (Cell Signaling #4499, 1:5000) and rabbit anti-phospho Histone H2A.X Ser 139 (Cell signaling #2577 ...
• Transferrin-dependent crosstalk between the intestinal tract and commensal microbes contributes for immune tolerance

  Xiaopeng Tang, et al., bioRxiv - Immunology 2020

  Quote: ... anti-phospho-interferon regulatory factor 3 (IRF3) (1:1□000 dilution, 29047S, Cell Signaling Technology, USA), anti-total-IRF3 (1:1□000 dilution ...
• Impact of Type II LRRK2 inhibitors on signalling and mitophagy

  Anna Tasegian, et al., bioRxiv - Neuroscience 2021

  Quote: ... The anti (pan)14-3-3 rabbit polyclonal antibody (#8312) and anti α-tubulin mouse monoclonal antibody (clone DM1A, mAb #3873) were purchased from Cell Signaling Technology. Anti-glyceraldehyde-3-phosphate dehydrogenase (GAPDH ...
• Effects of Emodin, a Plant-Derived Anthraquinone, on TGF-β1-Induced Cardiac Fibroblast Activation and Function

  Wayne Carver, et al., bioRxiv - Cell Biology 2021

  Quote: ... ERK1/2 or pERK1/2 (all from Cell Signaling Technology Inc, Danvers, MA, www.cellsignal.com). Nitrocellulose membranes were rinsed and incubated in horseradish peroxidase- conjugated anti-rabbit or anti-mouse serum as appropriate ...
• Regulation of early growth response-1 (Egr-1) gene expression by Stat1-independent type I interferon signaling and respiratory viruses

  Chilakamarti V. Ramana, bioRxiv - Genomics 2020

  Quote: ... and subjected to immunoblotting with the antibodies for phosphorylated Erk-1/2 (Thr202/Tyr 204) or total Erk-1/2 from Cell Signaling Technology (Beverly, MA). Blots were visualized by enhanced chemiluminescence western detection system (Pierce ...
• “Metabolic dysregulations of cancer cells with metastatic potential”

  Sara Abdul Kader, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MMP-2 (Cell signaling, #40994), Vimentin (Cell signaling ...
• Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics

  Anna L Koessinger, et al., bioRxiv - Cancer Biology 2021

  Quote: ... pERK1/2 (Cell Signaling #4370), AKT (Cell Signaling #9272) ...
• Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics

  Anna L Koessinger, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (Cell Signaling #4695), pERK1/2 (Cell Signaling #4370) ...
• Increased apoptotic priming of glioblastoma enables therapeutic targeting by BH3-mimetics

  Anna L Koessinger, et al., bioRxiv - Cancer Biology 2021

  Quote: ... BCL-2 (Cell Signaling #2762), BCL-xL (Cell Signaling #2762) ...
• Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD⁺ signaling

  Mustafa N. Okur, et al., bioRxiv - Cell Biology 2020

  Quote: ... mitofusin 2 (Cell signaling, #9482), total OXHOS rodent cocktail (Abcam ...
• Peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

  Kanji Okumoto, et al., bioRxiv - Cell Biology 2020

  Quote: ... and Erk1/2 (Cell Signaling), mouse monoclonal antibodies to HA (16B12 ...
• Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

  Brian Czaya, et al., bioRxiv - Cell Biology 2021

  Quote: ... ERK1/2 (4695, Cell Signaling), STAT3 (4904 ...
• Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

  Behnam Nabet, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (Cell Signaling, #4696), phospho-AKT S473 (Cell Signaling ...
• Peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

  Kanji Okumoto, et al., bioRxiv - Cell Biology 2020

  Quote: ... phospho-Erk1/2 (Cell Signaling), cytochrome P450 reductase (Santa Cruz Biotechnology ...
• LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer

  Donatella Delle Cave, et al., bioRxiv - Cancer Biology 2022

  Quote: ... MMP-2 (4022S, Cell Signaling), Vimentin (3932 ...
• COMBINATION THERAPIES TARGETING ALK-ABERRANT NEUROBLASTOMA IN PRECLINICAL MODELS

  Elizabeth R. Tucker, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK1/2 (Cell Signaling #4695), pERK1/2 (Cell Signaling #9101) ...
• Hemodynamic stress activates inflammatory responses and cell death through spectrin-dependent modulation of Store Operated Calcium Entry

  Lance Hsieh, et al., bioRxiv - Cell Biology 2022

  Quote: ... ERK1/2 (4695, Cell Signaling), SPTAN1 (MAB1622 ...
• Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

  Florian J. Bock, et al., bioRxiv - Cell Biology 2020

  Quote: ... pERK1/2 (4370, Cell Signaling), CASPASE 3 (9662 ...
• Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

  Florian J. Bock, et al., bioRxiv - Cell Biology 2020

  Quote: ... BCL-2 (2762, Cell Signaling), ERK1/2 (4695 ...
• Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

  Florian J. Bock, et al., bioRxiv - Cell Biology 2020

  Quote: ... ERK1/2 (4695, Cell Signaling), FGFR1 (9740 ...
• Double-targeted knockdown of miR-21 and CXCR4 inhibits malignant glioma progression by suppression of the PI3K/AKT and Raf/MEK/ERK pathways

  Feijiao Liu, Bo Yang, bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (Cell Signaling Technology), and phospho-ERK1/2 (Cell Signaling Technology) ...
• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... SOX-2 (Cell Signaling; #4900S), βIII-tubulin (Abcam ...
• Keratinocyte desmosomal cadherin Desmoglein 1 as a mediator and target of paracrine signaling in the melanoma niche

  Hope E. Burks, et al., bioRxiv - Cancer Biology 2022

  Quote: ... total ERK1/2 (Cell Signaling). The rabbit monoclonal antibody EP1576Y (ab52642 ...
• COMBINATION THERAPIES TARGETING ALK-ABERRANT NEUROBLASTOMA IN PRECLINICAL MODELS

  Elizabeth R. Tucker, et al., bioRxiv - Cancer Biology 2022

  Quote: ... pERK1/2 (Cell Signaling #9101), AKT (Cell Signaling #9272) ...
• Resistance to PSEN1-selective γ-secretase inhibitors in T-cell acute lymphoblastic leukemia

  Charlien Vandersmissen, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PEN-2 (#8598, Cell signaling), nicastrin (9C3 ...
• Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors

  Damien M. Rasmussen, et al., bioRxiv - Biophysics 2023

  Quote: ... and ERK1/2 (Cell Signaling). Membranes were washed and incubated for 1 h at RT with corresponding species-reactive secondary antibody and then imaged using an Odyssey CLx near-infrared imager (LI-COR Biosciences).
• Cell autonomous requirement of imprinted XCI in extra-embryonic polar trophoblast cells

  Feng Wang, et al., bioRxiv - Developmental Biology 2022

  Quote: ... pErk1/2 (Cell Signaling #9102), Fgfr2 (Abcam 10648) ...
• Site-1 Protease inhibits mitochondrial metabolism by controlling the TGF-β target gene MSS51

  Muhammad G. Mousa, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Smad 2 (5339, Cell Signaling); Phospho-AKT (4060 ...
• Prohibitin 2 is a Key Regulator of T Cell Proliferation and Effector Functions

  Johannes F. Vogt, et al., bioRxiv - Immunology 2024

  Quote: ... Erk1/2 (Cell Signaling #9102), p-Erk1/2 (Cell Signaling #9106) ...
• The Role of Alpha-Synuclein in Synucleinopathy: Impact on Lipid Regulation at Mitochondria–ER Membranes

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2024

  Quote: ... ERLIN-2 (Cell Signaling; 2959S), protein kinase C (Sigma-Aldrich ...
• YAP dysregulation triggers hypertrophy by CCN2 secretion and TGFβ uptake in human pluripotent stem cell-derived cardiomyocytes

  Orlando Chirikian, et al., bioRxiv - Cell Biology 2024

  Quote: ... pMST1/2 (Cell Signaling 49332) and GAPDH (Proteintech-60004-1 ...
• Targeted KRAS^G12V degradation elicits efficient and durable lung adenocarcinoma regression in vivo

  Alberto Martín, et al., bioRxiv - Cancer Biology 2024

  Quote: ... pERK1/2 (Cell Signaling, 9101), Phospho-S6 Ribosomal Protein Ser240/244 (Cell Signaling ...
• Abl kinases regulate FGF signaling independent of Crk phosphorylation to prevent Peters anomaly

  Hao Wu, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Erk1/2 (Cell Signaling, #4695), Abl (BD Pharmingen ...
• Endothelial Rho kinase controls blood vessel integrity and angiogenesis

  Martin Lange, et al., bioRxiv - Developmental Biology 2024

  Quote: ... pPAK1/2 (Cell Signaling, #2605S), PAK1/2/3 (Cell Signaling ...
• Endothelial Rho kinase controls blood vessel integrity and angiogenesis

  Martin Lange, et al., bioRxiv - Developmental Biology 2024

  Quote: ... pLIMK1/2 (Cell Signaling, # 3841S), LIMK1 (Cell Signaling ...