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751 - 800 of 10000+ citations for 5 1 3 benzothiazol 2 ylamino pentanoic acid since 2020

• The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

  Brian Hurwitz, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1/100 Phospho-Myosin Light Chain 2 (Ser19) (Cell Signaling Technologies, 3675); 1/250 p62/SQSTM (Cell Signaling Technologies ...
• Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

  Timothy N. Hoang, et al., bioRxiv - Immunology 2020

  Quote: ... pSTAT3 (Cell Signaling; Cat. No. 9145L at 1:200 for 2 hours), Iba-1 (BioCare ...
• A novel mechanism of bulk cytoplasmic transport by cortical dynein in Drosophila ovary

  Wen Lu, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit phospho-MLC (pMLC 2/Ser19, 1:100, Cell Signaling, Cat# 3671); mouse monoclonal anti-DHC antibody (2C11-2 ...
• Negative durotaxis: cell movement toward softer environments

  Aleksi Isomursu, et al., bioRxiv - Biophysics 2020

  Quote: ... rbt anti-ERK1/2 (Cell Signaling Technology, 9102, 1:1000 for WB), rbt anti-p-ERK1/2 (T202/Y204 ...
• Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

  Parishmita Sarma, et al., bioRxiv - Biochemistry 2022

  Quote: ... and anti-tERK1/2 (1:5000; Cell Signaling Technology, Cat. no. 9102). CXCR7pp2 was synthesized at the Tufts University Core Facility.
• Deletion of the microglial transmembrane immune signaling adaptor TYROBP ameliorates Huntington’s disease mouse phenotype

  Jordi Creus-Muncunill, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-p44/42 MAPK (Erk1/2) Antibody (1:1000, #9102, Cell Signaling), anti-C1q [4.8] (1:500 ...
• Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer progression

  Jason J. Northey, et al., bioRxiv - Cancer Biology 2022

  Quote: ... p44/42 MAPK (ERK1/2) (Cell Signaling Technology, Cat. #: 9102, 1:1000), phospho-PR (S294 ...
• Transferrin-dependent crosstalk between the intestinal tract and commensal microbes contributes for immune tolerance

  Xiaopeng Tang, et al., bioRxiv - Immunology 2020

  Quote: ... anti-total-IκBα (1:2□000 dilution, 4814T, Cell Signaling Technology, USA), anti-phospho-NF-κB p65 (1:1□000 dilution ...
• Biased agonists of the chemokine receptor CXCR3 differentially drive formation of G_αi:β-arrestin complexes

  Kevin Zheng, et al., bioRxiv - Biochemistry 2020

  Quote: ... phosphorylated extracellular regulated kinase 1/2 (ERK) (Cell Signaling Technology, Danvers, MA) and total ERK (Millipore ...
• Jak2^V617F Reversible Activation Shows an Essential Requirement for Jak2^V617F in Myeloproliferative Neoplasms

  Andrew Dunbar, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and phospho-44/42 MAPK (Erk1/2) (Cell Signaling 4376, 1:100). Pictures were taken at 100X ...
• ATP allosterically stabilizes Integrin-linked kinase for efficient force generation

  Isabel M. Martin, et al., bioRxiv - Biophysics 2021

  Quote: ... phospho-Myosin Light Chain 2 (Thr18/Ser19) (Cell Signaling; 3674; 1:200), Paxillin (BD Transduction Laboratories ...
• Oxidative Stress and Neuroinflammation in a Rat Model of Co-Morbid Obesity and Psychogenic Stress

  Jose M. Santiago Santana, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-rabbit SOD-2 (1:2000; catalog #13141S; Cell Signaling, Danvers, MA); anti-rabbit GFAP (1:5000 ...
• Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma

  Odessa R. Yabut, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-phospho-Erk1/2 (1:250 dilution; Cat. #: 4370, Cell Signaling); γH2AX (1:100 dilution ...
• Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling

  Chirag Vasavda, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-phospho-ERK1/2 (T202/Y204) (Cell Signaling 4370, 1:2000), rabbit anti-ERK1/2 (Cell Signaling 4695 ...
• TOP-2 is differentially required for the proper maintenance of cohesin on meiotic chromosomes in C. elegans spermatogenesis and oogenesis

  Christine Rourke, Aimee Jaramillo-Lambert, bioRxiv - Genetics 2021

  Quote: ... rabbit anti-AIR-2 [(1:500) Figure 2B] (Cell Signaling Technology, 2914S), Histone H3 phospho-T3 (1:750 ...
• Single Serine on TSC2 Exerts Biased Control over mTORC1 Activation by ERK1/2 but Not Akt

  Brittany L. Dunkerly-Eyring, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-p44/42 MAPK (ERK1/2) (Cell Signaling Technology, 1:1000). Total protein stain used was Revert Total Protein Stain (Licor) ...
• Metformin-mediated mitochondrial protection post-cardiac arrest improves EEG activity and confers neuroprotection and survival benefit

  Muhammad Shoaib, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Total AMPK β1/2 (1:1000; Cell Signaling Technology, Beverly, MA). Detection used anti-rabbit horseradish peroxidase–conjugated secondary antibody (1:2000 ...
• Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function

  Rajan K C, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p-p44/42 MAPK (pERK1/2) (Cell Signaling Technology, 9101S, 1:1,000) and β-actin (Cell Signaling Technology ...
• Angpt1 binding to Tie1 regulates the signaling required for lymphatic vessel development in zebrafish

  Nanami Morooka, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-Phospho-p44/42 MAPK (Erk1/2) (1:500, Cell signaling), and mouse anti-RFP (1:500 ...
• An atlas of epithelial cell states and plasticity in lung adenocarcinoma

  Guangchun Han, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p44/42 MAPK (ERK1/2, rabbit, Cell Signaling Technology, 9102, 1:2000), or S6 (E.573.4 ...
• Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression

  Giusy Pizzirusso, et al., bioRxiv - Neuroscience 2024

  Quote: ... 1:1000 anti-Synaptotagmin-2 polyclonal rabbit antibody (#60889, Cell Signaling Technology), 1:1000 anti-GABA-A Receptor beta 3 polyclonal rabbit antibody (#NB300-199 ...
• Diet-induced obesity results in endothelial cell desensitization to VEGF-A and permanent islet vascular dysfunction

  Yan Xiong, et al., bioRxiv - Physiology 2023

  Quote: ... Erk1/2 antibody (rabbit, 1:2000; all from Cell Signaling Technology, USA), and α-tubulin antibody (mouse,1:1000 ...
• Subfamily C7 Raf-like kinases MRK1, RAF26, and RAF39 regulate immune homeostasis and stomatal opening in Arabidopsis thaliana

  Márcia Gonçalves Dias, et al., bioRxiv - Plant Biology 2023

  Quote: ... 1:2,000 rabbit anti-p44/42 MAPK (Erk1/2) (Cell Signaling 9102S); 1:10,000 goat anti-rabbit-IgG (Sigma A0545) ...
• PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

  Maria B. Campaña, et al., bioRxiv - Cell Biology 2023

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:1000; 9101; Cell Signaling Technology, Inc.); ERK1/2 (1:1000 ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... phospho-ERK1/2 (Thr202/Tyr204) (1:1000, Cell Signaling Technology, Cat# 9106), ERK1/2 (1:1000 ...
• Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

  Zhuxuan Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Phospho-p44/42 MAPK (Erk1/2) (#4370, Cell Signaling Technology, 1:1000), ERK (#9102S ...
• Retinoid acid receptor β mechanically regulates the activity of pancreatic cancer cells

  Carlos Matellan, et al., bioRxiv - Bioengineering 2022

  Quote: ... or anti-MLC-2 antibodies (Cell Signaling Technology, 3672S, Rabbit, 1:100) and anti-PAN cytokeratin (Abcam ...
• Endosome dysfunction leads to gain-of-function TLR7 and human lupus

  Harshita Mishra, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Phospho-p44/42 (ERK1/2) (1:1000, 197G2, 4377T, Cell Signaling), anti-p44/42 (ERK1/2 ...
• Drug-Induced p53 Activation Promotes Acinar Cell Identity and Prevents Pancreatic Cancer Initiation

  Jennifer J Twardowski, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit monoclonal anti-p-ERK1/2 (Cell Signaling Technology 4370S, 1:100), rabbit polyclonal anti-p53 (Invitrogen PA5-88098 ...
• A combination of the geroprotectors trametinib and rapamycin is more effective than either drug alone

  Lisonia Gkioni, et al., bioRxiv - Physiology 2024

  Quote: ... and total ERK1/2 (1:1000, anti-rabbit, Cell Signaling Technology, 4695) in 5% fatty-acid free BSA in TBS-T at 4°C overnight ...
• Rigosertib Reverses Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome

  Levi Legler, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and anti-phospho-ERK 1/2 (Thr202/Tyr204) (#9101) (Cell Signaling Technology). Visualization of the primary antibody binding was performed using the Li-Cor anti-rabbit 680 IRDye system in conjunction with the Li-Cor Odyssey FC ...
• Gestational arsenite exposure alters maternal postpartum heart size and induces Ca²⁺ handling dysregulation in cardiomyocytes

  Nicole Taube, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... p44/42 MAPK (ERK1/2) (1:1000, Rabbit mAb, Cell Signaling, 9102S), p-p44/42 MAPK (T202/Y204 ...
• Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging

  Hui Li, et al., bioRxiv - Neuroscience 2020

  Quote: ... The membranes were blocked with 5% non-fat dry milk for 2 h at RT and incubated overnight at 4°C with rabbit anti-phospho-ERK1/2 (1:2000, Cell Signaling), anti-phospho-Ser473-Akt (1:2000 ...
• Levels of p53 expression determine the competitive ability of embryonic stem cells during the onset of differentiation

  Salvador Perez Montero, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Cells were then incubated with primary antibody (Cleaved Caspase 3 #9664, Cell signaling,1:200 dilution) for 1 hour at room temperature ...
• Dpp and Hedgehog promote the Glial response to neuronal damage in the developing Drosophila Visual system

  Sergio B. Velarde, et al., bioRxiv - Neuroscience 2020

  Quote: ... The following primary antibodies were used: rabbit anti-Phospho-histone 3 1:200 (Cell Signaling Technology), rabbit anti-cleaved Dcp1 1:200 (Cell Signaling Technology) ...
• Amyloid beta acts synergistically as a pro-inflammatory cytokine

  Thomas J. LaRocca, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and signal (protein expression) was normalized to glyceraldehyde-3-phosphate dehydrogenase (GAPDH; Cell Signaling, 1:1000).
• Kirigami electronics for long-term electrophysiological recording of human neural organoids and assembloids

  Xiao Yang, et al., bioRxiv - Neuroscience 2023

  Quote: ... cleaved caspase-3 (Asp175) antibody (rabbit, Cell Signaling Technology, 9661, 45 and 47, 1:200 dilution), anti-neurofilament heavy polypeptide antibody (mouse ...
• Synthetic torpor triggers a neuroprotective and regulated mechanism in the rat brain, favoring the reversibility of Tau protein hyperphosphorylation

  Fabio Squarcio, et al., bioRxiv - Neuroscience 2022

  Quote: ... were detected using the rabbit polyclonal antibody for cleaved-Caspase 3 (Asp175) (Cell Signaling, 1:300), followed by a Donkey Anti-rabbit IgG conjugated with Alexa-594 (Thermo Fisher ...
• Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function

  Caleb C.S. Calhoun, et al., bioRxiv - Neuroscience 2024

  Quote: ... was used at 3:1000 and pErk antibody was used at 1:500 (Cell Signaling, #4370). Typically ...
• Rhes, a Striatal Enriched Protein, Regulates Post-Translational Small-Ubiquitin-like-Modifier (SUMO) Modification of Nuclear Proteins and Alters Gene Expression

  Oscar Rivera, et al., bioRxiv - Biochemistry 2020

  Quote: ... #2983), Histone H3 (1:10,000, #4499), MEK1/2 (1:1000, #8727) and LDH (1:5000, #2012;) were from Cell Signaling Technology, Inc ...
• Role of miR-181c in Diet-Induced Obesity Through Regulation of Lipid Synthesis in Liver

  Kei Akiyoshi, et al., bioRxiv - Cell Biology 2021

  Quote: ... the membrane was incubated with antibody that recognizes proteins IDH 1 (1:1000) and IDH 2 (1:1000) (Cell Signaling, MA) and α-Tubulin (Abcam ...
• Uncovering the mechanistic basis of intracellular Raf inhibitor sensitivity reveals synergistic cotreatment strategies

  Ethan G. Stoddard, et al., bioRxiv - Cell Biology 2024

  Quote: 14-3-3 (pan) E9S9M Rabbit mAb (Cell Signaling Technology, cat. no. 95422)
• Mechanisms of translation inhibition and suppression of Stress Granule formation by cisplatin

  Paulina Pietras, et al., bioRxiv - Cell Biology 2021

  Quote: ... and Cleaved Caspase 3 (#9664, 1:400 dilution for IF) and anti-Rsk2 (#5528; 1:200 dilution for IF) were purchased from Cell Signaling Technology. Anti-Tubulin α (66031-1-Ig ...
• The Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy

  Dale P. Corkery, et al., bioRxiv - Cell Biology 2020

  Quote: ... Galectin-3 (#87985, IF: 1:400) and Na/K-ATPase α1 (#23565, IF: 1:100) antibodies were purchased from Cell Signaling Technology. Anti-beta-actin antibody (A2228 ...
• SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns

  Kazuhiro Fukumura, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-SF3B1 (1:500 dilution; D221-3, MBL Life Science) and anti-phosph-SF3B1(Thr313) (1:500 dilution; D8D8V, Cell Signaling Technology). After washing three times with PBS ...
• A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments

  Christopher Chidley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... incubation for 1–3 hr at RT with 1:5000 secondary antibody (Cell Signaling Technology goat HRP-linked Anti rabbit IgG #7074), and 3 more 5 min washes with TBST ...
• Regulation of Store-Operated Ca²⁺ Entry by IP₃ Receptors Independent of Their Ability to Release Ca²⁺

  Pragnya Chakraborty, et al., bioRxiv - Cell Biology 2023

  Quote: ... washed with TBST (3 ×10 min), incubated (1 hr, 20°C) in TBST containing HRP-conjugated secondary antibody (1:3000 anti-mouse, Cell Signaling Technology Cat# 7076S ...
• A critical role of a eubiotic microbiota in gating proper immunocompetence in Arabidopsis

  Bradley C. Paasch, et al., bioRxiv - Plant Biology 2023

  Quote: ... Blots for detecting phosphorylated MAPK were blocked in 5% BSA and immunoblotted with a phosphor-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) antibody (Cell Signaling). Horseradish peroxidase-conjugated anti-rabbit antibody produced in goat (Agrisera ...
• Loss of genital epithelial barrier function is greater with depot-medroxyprogesterone acetate than intravaginal rings that release etonogestrel and ethinyl estradiol

  Mohan Liu, et al., bioRxiv - Immunology 2023

  Quote: ... Endogenous peroxidase activity was quenched by 3% hydrogen peroxidase prior to 4-hour incubation at 4°C with 5% normal goat serum (Cell Signaling Technology®, Danvers, MA) and rabbit anti-DSG1 (clone EPR677766(B) ...
• Constitutive signal bias mediated by the human GHRHR splice variant 1

  Zhaotong Cong, et al., bioRxiv - Molecular Biology 2021

  Quote: ... The membranes were blocked with 5% BSA in TBST buffer for 2 h at RT and incubated overnight at 4°C with primary antibodies against ERK1/2 (1:1000; 9102s, Cell Signaling Technology), pERK1/2 (1:1000 ...