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7801 - 7850 of 10000+ citations for 7 hydroxy 1H 1 2 4 triazolo 1 5 a pyrimidin 5 one since 2019

• Gene dosage effects of polyA track engineered hypomorphs

  Geralle Powell, et al., bioRxiv - Genetics 2021

  Quote: ... or 1:10,000 anti-rabbit secondary antibody (Cell Signaling, 7074S) overnight ...
• Loss of Protein Kinase D2 Activity Protects Against Bleomycin-induced Dermal Fibrosis in Mice

  Liping Chen, et al., bioRxiv - Genetics 2021

  Quote: ... anti-p-PKD1 (ser744/748) (Cell signaling technology, 1:1000), anti-PKD2 (ABclonal ...
• Extraembryonic endoderm cells induce neuroepithelial tissue in gastruloids

  Noémie M. L. P. Bérenger-Currias, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-E-cadherin (1:200, 3195, Cell Signaling Technology), rabbit anti-PAX6 (1:100 (cerebral organoids ...
• Differential regulation of cranial and cardiac neural crest by Serum Response Factor

  Colin J. Dinsmore, Philippe Soriano, bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-cleaved Caspase 3 (Cell Signaling 9665, 1:400), rabbit anti-phospho Histone H3 (Ser10 ...
• Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents

  Raghu Ram Katreddi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... *Rabbit anti-NICD activated (1:75, D3B8, Cell Signaling Tech), *Mouse anti-DsRd (1:500 ...
• SLX4IP-mediated telomere maintenance is essential for androgen receptor-independent castration-resistant prostate cancer

  Tawna L. Mangosh, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Primary antibody dilutions: 1:20 000 GAPDH (Cell Signaling, 2118), 1:5 000 SLX4IP (Sigma ...
• A calcineurin-mediated scaling mechanism that controls a K⁺-leak channel to regulate morphogen and growth factor transcription

  Chao Yi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Anti-lef1 (1:1000, Cell Signaling Technology, 2230T, RRID: AB_823558)) ...
• RNA-guided cell targeting with CRISPR/RfxCas13d collateral activity in human cells

  Peiguo Shi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Cleaved Caspase 3 antibody (Cell signaling technology, 9661T, 1:500) was used for detecting the expression of cleaved Caspase 3 ...
• Opposing roles of p38α-mediated phosphorylation and arginine methylation in driving TDP-43 proteinopathy

  Mari Aikio, et al., bioRxiv - Molecular Biology 2021

  Quote: ... mouse Histone H3 (96C10) (1:1,500; 3638, Cell Signaling Technology), rabbit Mono-Methyl Arginine (R*GG ...
• Unraveling three-dimensional chromatin structural dynamics during spermatogonial differentiation

  Yi Zheng, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and rabbit anti-KIT (1: 200; 3074S, Cell Signaling Technology). The corresponding isotype IgGs in place of the primary antibodies were used as negative controls ...
• Vestibular and auditory hair cell regeneration following targeted ablation of hair cells with diphtheria toxin in zebrafish

  Erin Jimenez, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit cleaved Caspase-3 (Cell Signaling #9661, 1:300-dilution), Alexa Fluor 568 goat anti-rabbit IgG (1:1000-dilution).
• RhoA- and Ran-induced antagonistic forces underlie symmetry breaking and spindle rotation in mouse oocytes

  Benoit Dehapiot, et al., bioRxiv - Developmental Biology 2020

  Quote: ... pMLC2 (1/200 dilution, Rabbit polyclonal, Cell Signaling Technology #3671), RhoA (1/100 dilution ...
• Palmitic acid induces inflammation in placental trophoblasts and impairs their migration toward smooth muscle cells through plasminogen activator inhibitor-1

  Amanda M. Rampersaud, et al., bioRxiv - Developmental Biology 2020

  Quote: ... focal adhesion kinase (FAK; D507U, 1:1000, Cell Signaling Technology), and phosphorylated FAK (8556 ...
• Membrane potential regulates Hedgehog signaling and compartment boundary maintenance in the Drosophila wing disc

  Maya Emmons-Bell, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-cleaved-DCP1 (Asp216, 1:250; Cell Signaling Technology), and rabbit anti-GFP (#TP401 ...
• Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria

  Kuan Zhang, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-PDGFRA (1:150, Cell Signaling Technology, Cat# 3164), rabbit anti-phospho-PDGFRA (Tyr754 ...
• GCNA is a histone binding protein required for spermatogonial stem cell maintenance

  Jonathan Ribeiro, Gerry P. Crossan, bioRxiv - Physiology 2022

  Quote: ... anti-Nanog (1:1000, catalog no. 8822, Cell Signaling Technology); anti-TOP2 (1:1000 ...
• Iron Deficiency Induces Heart Failure with Ectopic Cardiac Calcification in Mice with Metabolic Syndrome

  Yoshiro Naito, et al., bioRxiv - Pathology 2022

  Quote: ... anti-β-catenin (#9587, Cell Signaling Technology; dilution 1:1000), and anti-GAPDH (#2118 ...
• A PCNA-K164R mutation impinges on origin activation and mitotic DNA synthesis

  Wendy Leung, et al., bioRxiv - Molecular Biology 2022

  Quote: ... rabbit anti-p-p53 (S15) (Cell Signaling, 9284S; 1:500), mouse anti-p53 (Santa Cruz ...
• Angiomotin isoform 2 promotes binding of PALS1 to KIF13B at the base of primary cilia and suppresses ciliary elongation

  Stine Kjær Morthorst, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-GAPDH (Cell Signaling Technology, cat# 2118S; 1:1,000), rabbit anti-AMOT (kindly provided by Dr ...
• Genetic instability from a single S-phase after whole genome duplication

  Simon Gemble, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-CDT1 (1/500; 8064S from Cell Signaling, RRID:AB_10896851), rabbit anti-Treslin (1/500 ...
• Signaling from the RNA sensor RIG-I is regulated by ufmylation

  Daltry L. Snider, et al., bioRxiv - Immunology 2022

  Quote: ... R-anti-14-3-3ε (Cell Signaling Technology, 1:1000), M-anti-Flag M2 (Sigma ...
• Human Cytomegalovirus modifies placental small extracellular vesicle secretion and composition towards a proviral phenotype to enhance infection of fetal recipient cells

  Mathilde Bergamelli, et al., bioRxiv - Cell Biology 2022

  Quote: ... or SOX2 (1/500 of stock; Cell Signaling D6D9 #3579). Secondary antibody incubation (Goat anti mouse or rabbit - Alexa-fluor 488 or 594 (2 μg/ml ...
• Deficiency in endocannabinoid synthase DAGLB contributes to Parkinson’s disease and dopaminergic neuron dysfunction

  Zhenhua Liu, et al., bioRxiv - Neuroscience 2021

  Quote: ... Rabbit monoclonal anti-Cre Recombinase (Cell Signaling, 12830S, 1:500), Mouse monoclonal anti-GAPDH (Sigma-Aldrich ...
• Deficiency in endocannabinoid synthase DAGLB contributes to Parkinson’s disease and dopaminergic neuron dysfunction

  Zhenhua Liu, et al., bioRxiv - Neuroscience 2021

  Quote: ... Rabbit monoclonal anti-HA-Tag (Cell Signaling, 3724S, 1:500), Rabbit monoclonal anti-Cre Recombinase (Cell Signaling ...
• Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

  Yu-En Lin, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-alpha tubulin (Cell Signaling, #2144, 1:10000), followed by blotting with secondary antibodies peroxidase-conjugated goat anti-rabbit IgG (Jackson Lab ...
• Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

  Yu-En Lin, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-phospho-Smad2 (Ser465/467, Cell Signaling, 3108T, 1:1000); anti-Smad3 (Cell Signaling ...
• Intersectional, anterograde transsynaptic targeting of the neurons receiving monosynaptic inputs from two upstream regions

  Takuma Kitanishi, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-DARPP-32 (1:800, 2306S, Cell Signaling Technology), goat anti-ChAT (1:100 ...
• Impaired KDM2B-mediated PRC1 recruitment to chromatin causes neural stem cell senescence and ASD/ID-like behavioral deficits

  Yuen Gao, et al., bioRxiv - Neuroscience 2021

  Quote: ... or rabbit anti-GFAP (1:300, 12389, Cell Signaling technology). After washing with DPBS ...
• Age-dependent Effect Imposed by Rotenone Exposure

  Madeleine C. Moseley, et al., bioRxiv - Neuroscience 2021

  Quote: ... P-H3 (Millipore #06-570; Cell Signaling #9307S, 1:200), NPY (Bioss #bs0071R ...
• Characterization of early Alzheimer’s-like pathological alterations in non-human primates with aging: a pilot study

  Hannah Jester, et al., bioRxiv - Molecular Biology 2021

  Quote: ... p-4E-BP1 (1:1000; Thr37, Thr46) (Cell Signaling, Cat#), 4E-BP1 (1:1000 ...
• Extensive and diverse patterns of cell death sculpt neural networks in insects

  Sinziana Pop, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-cleaved Drosophila Dcp1 (1:100; Asp216, Cell Signaling), guinea pig anti-Syncrip (1:100 ...
• Arap1 Loss Causes RPE Phagocytic Dysfunction and Subsequent Photoreceptor Death

  Andy Shao, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and rabbit anti-Beta-actin IgG (1:4000, Cell Signaling) overnight at 4°C ...
• The hallucinogenic serotonin_2A receptor agonist, DOI, promotes CREB-dependent gene expression of specific plasticity-associated genes in the rodent neocortex

  Lynette A. Desouza, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-pCREB (1:1000; Cell Signaling Technology, MA, USA) or goat anti-5-HT2A receptor (1:500 ...
• Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2

  Polina Kosillo, et al., bioRxiv - Neuroscience 2021

  Quote: ... and phospho-S6 (Ser240/244) (1:1000, Cell Signaling: 5364S). The following secondary antibodies were used ...
• Nuclear Export of Drosophila PERIOD contributes to temperature compensation of the circadian clock

  Astrid Giesecke, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1:2000 for mouse anti HA-tag (6E2 Cell signaling), and 1:2000 for anti-CLK (3) ...
• The chromatin remodeler Ino80 mediates alternative RNAPII pausing site determination

  Youngseo Cheon, et al., bioRxiv - Molecular Biology 2021

  Quote: ... and anti-tubulin (Cell Signaling, 2144S; used at 1:4000).
• End-of-life targeted auxin-mediated degradation of DAF-2 Insulin/IGF-1 receptor promotes longevity free from growth-related pathologies

  Richard Venz, et al., bioRxiv - Molecular Biology 2021

  Quote: ... HRP-conjugated goat anti-mouse (Cell Signaling #7076, 1:2000) secondary antibodies were used to detect the proteins by enhanced chemiluminescence (Bio-Rad #1705061) ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... phospho-S6K1 (1:1000, Cat#: 9234, Cell Signaling, Danvers, MA), total S6K1 (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... total AKT (1:1000, Cat#: 9272, Cell Signaling, Danvers, MA), β-catenin (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... phospho-p38 (1:1000, Cat#: 9216, Cell Signaling, Danvers, MA), total p38 (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... phospho-JNK (1:1000, Cat#: 4668, Cell Signaling, Danvers, MA), total JNK (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... phospho-AKT (1:1000, Cat#: 4060, Cell Signaling, Danvers, MA), total AKT (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and GAPDH (1:1000, Cat#: 2118, Cell Signaling, Danvers, MA). Full length gels provided in supplemental figures 1 and 2 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... total p38 (1:1000, Cat#: 9212, Cell Signaling, Danvers, MA), phospho-S6K1 (1:1000 ...
• Extracellular vesicle microRNA cargo engineering reveals critical mechanisms underlying therapeutic efficacy

  Lindsey M. Euscher, et al., bioRxiv - Bioengineering 2022

  Quote: ... and rabbit cleaved caspase-3 (1:200; Asp175, Cell Signaling). Alexa Fluor 488- ...
• Tumor elimination by clustered microRNAs miR-306 and miR-79 via non-canonical activation of JNK signaling

  Zhaowei Wang, Xiaoling Xia, Tatsushi Igaki, bioRxiv - Cell Biology 2022

  Quote: ... HRP-linked antibody (Cell Signaling Technology, Cat #7074, 1:5000) or anti-guinea pig IgG ...
• Mechanisms of A-type lamin targeting to nuclear ruptures are disrupted in LMNA- and BANF1-associated progerias

  Rhiannon M. Sears, Kyle J. Roux, bioRxiv - Cell Biology 2022

  Quote: ... and rabbit anti-Ankle2 (1:1000; ab225905; Cell Signaling Technology). Mouse monoclonal anti-tubulin (1:5000 ...
• Separate to operate: the centriole-free inner core of the centrosome regulates the assembly of the intranuclear spindle in Toxoplasma gondii

  Ramiro Tomasina, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-HA at 1:200 (Cell Signaling, Cat #: 3724S), mouse anti-IMC-1(16) ...
• NOX4 inhibition promotes the remodeling of dystrophic muscle

  David W. Hammers, bioRxiv - Cell Biology 2022

  Quote: ... and anti-active caspase-3 (1:1000; Cell Signaling #9661) primary antibodies ...
• Link between aging and atheroprotection in Mif-deficient atherosclerotic mice

  Christine Krammer, et al., bioRxiv - Immunology 2021

  Quote: ... and rabbit anti-mouse Ki67 (1:200, #9129T, Cell Signaling). Afterwards ...