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7701 - 7750 of 10000+ citations for 6 4 METHOXY PHENYL 3 METHYL IMIDAZO 2 1 B THIAZOLE 5 CARBALDEHYDE since 2019

• 5-hydroxymethylcytosines regulate gene expression as a passive DNA demethylation resisting epigenetic mark in proliferative somatic cells

  Alex Wei, et al., bioRxiv - Genomics 2023

  Quote: ... 1:3000 anti-ACTB (Cell Signaling Technology, 3700S) overnight in 4°C while shaking ...
• HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance

  Hongbo Ling, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Beclin-1 (Cell Signaling Technology, #3495, RRID:AB_1903911), anti-p62 (Cell Signaling Technology ...
• GRAMD2⁺ alveolar type I cell plasticity facilitates cell state transitions in organoid culture

  Hua Shen, et al., bioRxiv - Cell Biology 2023

  Quote: ... SOX2 (1:100, #4900, Cell Signaling, Danvers, MA), HOPX (1:50 ...
• Human Papillomavirus 16 replication converts SAMHD1 into a homologous recombination factor and promotes its recruitment to replicating viral DNA

  Claire D. James, et al., bioRxiv - Cancer Biology 2023

  Quote: ... phospho-SAMHD1 1/500 (Cell Signaling Technology, 89930) GAPDH 1/10,000 (Santa Cruz ...
• ATR promotes mTORC1 activation via de novo cholesterol synthesis in p16-low cancer cells

  Naveen Kumar Tangudu, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HRP-linked (Cell Signaling Technology, 7074; 1:5000).
• Adaptive epigenetic regulation of neuronal metabolism by a mitochondrial redox signal

  Marius W. Baeken, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-acetylated lysine (9441, Cell Signaling, 1:1000), anti-DNMT3B (67259 ...
• Long noncoding RNA Hottip maintained skeletal homeostasis via suppressing the enhancer of zeste homolog 2 (Ezh2)/histone methylation regulatory axis

  Zhi-Peng Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... and H3K27me3 (1:100; Cell Signaling Technology, USA). The nonimmune IgG control samples were used as a mock ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... STAM1 Antibody (13053, 1:30, Cell Signaling Technology), anti-CHMP7 (sc-271805 ...
• Fibroblast Nrf2 inhibits profibrotic transcription with Ddx54 and mitigates pathological fibrosis in the mouse heart and kidney

  Toshiyuki Nishiji, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-Nrf2 (Cell Signaling, #12721, 1/1000), mouse anti-β-actin (Sigma Aldrich ...
• Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

  Zhuxuan Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and GAPDH (#2118L, Cell Signaling Technology, 1:500) were detected using the appropriate HRP-conjugated secondary antibodies according to the manufacturer’s instructions.
• Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

  Zhuxuan Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... KRAS(G12D) (#14429S, Cell Signaling Technology, 1:500), and GAPDH (#2118L ...
• Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations

  Maria Victoria Hinckelmann, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-phopsho-cofilin (Cell signaling, 1:1000) and mouse anti-actin (Sigma ...
• Olfactory learning in Drosophila requires O-GlcNAcylation of mushroom body ribosomal subunits

  Haibin Yu, et al., bioRxiv - Cell Biology 2023

  Quote: ... and GFP (1:200, Cell Signaling Technology, 2955).
• T cells Use Focal Adhesions to Pull Themselves Through Confined Environments

  Alexia Caillier, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 1:1000 Integrin β3 (Cell Signaling, 13166). They were then rinsed 3X 5 min with PBS-T before incubation for 30min in 5% non fat dry milk in PBS-T with secondary antibody ...
• The ability of the LIMD1 and TRIP6 LIM domains to bind to f-actin under strain is critical for their tension dependent localization to adherens junctions and association with the Hippo pathway kinase LATS1

  Samriddha Ray, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti -LATS1(1:500, Cell Signaling,3477), rabbit anti - LIMD1 (1:500 ...
• The ability of the LIMD1 and TRIP6 LIM domains to bind to f-actin under strain is critical for their tension dependent localization to adherens junctions and association with the Hippo pathway kinase LATS1

  Samriddha Ray, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-GAPDH (1:1000, Cell signaling, 5174). For detection of biotinylated proteins by western blotting IRDye® 680RD Streptavidin (LI-COR Biosciences ...
• Instant Assembly of Collagen for Scaffolding, Tissue Engineering, and Bioprinting

  Xiangyu Gong, et al., bioRxiv - Bioengineering 2023

  Quote: ... anti-SOX17 (D1T8M, Cell Signaling Technology, 1:50), anti-CDX2 (D11D10 ...
• Instant Assembly of Collagen for Scaffolding, Tissue Engineering, and Bioprinting

  Xiangyu Gong, et al., bioRxiv - Bioengineering 2023

  Quote: ... anti-CDX2 (D11D10, Cell Signaling Technology, 1:50), anti-Nanog (sc-293121 ...
• Instant Assembly of Collagen for Scaffolding, Tissue Engineering, and Bioprinting

  Xiangyu Gong, et al., bioRxiv - Bioengineering 2023

  Quote: ... anti-OCT4 (#2750, Cell Signaling Technology, 1:200). Secondary antibodies ...
• Targetable leukemia dependency on noncanonical PI3Kγ signaling

  Qingyu Luo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-ubiquitin (1:1000; 43124S; Cell Signaling Technology), anti-SPI1 (1:1000 ...
• Targetable leukemia dependency on noncanonical PI3Kγ signaling

  Qingyu Luo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-PDK1 (1:1000; 3062S; Cell Signaling Technology), and anti-β-actin (1:5000 ...
• Targetable leukemia dependency on noncanonical PI3Kγ signaling

  Qingyu Luo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-PAK1 (1:1000; 2602S; Cell Signaling Technology), anti-p-AKT-S473 (1:2000 ...
• Targetable leukemia dependency on noncanonical PI3Kγ signaling

  Qingyu Luo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-SPI1 (1:1000; 2258S; Cell Signaling Technology), anti-ASH2L (1:2000 ...
• Targetable leukemia dependency on noncanonical PI3Kγ signaling

  Qingyu Luo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-AKT (1:1000; 4691S; Cell Signaling Technology), anti-p-PDK1-S241 (1:1000 ...
• Histone monoaminylation dynamics are regulated by a single enzyme and promote neural rhythmicity

  Qingfei Zheng, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-Tgm2 (1:500, Cell Signaling 3557S), and rabbit anti-H3 (1:50000 ...
• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma

  Feras E. Machour, et al., bioRxiv - Molecular Biology 2023

  Quote: ... γH2AX (Cell Signaling Technology cat.no. 2577, 1:1000), pChk1-S345 (Cell Signaling Technology cat.no ...
• The NAD⁺ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC derived Cortical Organoid of Alpers’ Disease

  Yu Hong, et al., bioRxiv - Neuroscience 2023

  Quote: ... NeuN (1:500; Cell Signaling, cat. no. 24307), MAP2 (1:1000 ...
• Post-translational regulation of the Numb/Notch pathway in neurogenesis and cancer by Dlk2

  Stephanie.B Telerman, et al., bioRxiv - Cell Biology 2023

  Quote: ... PhosphoNumb Ser276 (1:200, Cell signaling Technology 4140S), Mdm2/HDM2 (1:200 ...
• Downregulation of a cell polarity protein potentiates Chikungunya Virus infection in host cells

  Ramesh Kumar, et al., bioRxiv - Cell Biology 2023

  Quote: ... beta-actin (1:1000, Cell signaling Technology 4967), beta-tubulin (1:200 ...
• Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo

  Yuqi Gui, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit against SNAP25 (1:2,000; Cell Signaling #3926), mouse against Histone H1 (1:500 ...
• DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identity

  Coral K. Wille, et al., bioRxiv - Genetics 2023

  Quote: ... and α-TUBULIN (1:3000; Cell Signaling, 3873). Immunoblot images were captured with ECL on an ImageQuant LAS 4000 or with LI-COR Odyssey ...
• DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identity

  Coral K. Wille, et al., bioRxiv - Genetics 2023

  Quote: ... total Histone H3 (1:3000; Cell Signaling, 3638S) and α-TUBULIN (1:3000 ...
• CCR2-targeting pepducins reduce T cell-nociceptor interaction driving bone cancer pain

  Élora Midavaine, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-pP38 (1:100, Cell Signaling, #4511), rabbit anti-Ki67 (1:100 ...
• Dynamic mRNA stability changes buffer transcriptional activation during neuronal differentiation and are regulated by RNA binding proteins

  Yuan Zhou, et al., bioRxiv - Molecular Biology 2023

  Quote: ... β-tubulin-III (Cell signaling, Cat# 2128, 1:200), or Synaptophysin (Abcam ...
• Astrocytes regulate neuronal network burst frequency through NMDA receptors species- and donor-specifically

  Noora Räsänen, et al., bioRxiv - Neuroscience 2023

  Quote: ... GRIN1 rabbit (1:500, Cell Signaling Technologies, 5704), s100β rabbit (1:100,Abcam ...
• A multi-strategy antimicrobial discovery approach reveals new ways to combat Chlamydia

  Magnus Ölander, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit-anti-ATG5 (1:1000; Cell Signaling 12994), rabbit-anti-ATG7 (1:1000 ...
• A multi-strategy antimicrobial discovery approach reveals new ways to combat Chlamydia

  Magnus Ölander, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit-anti-TBK1 (1:1000; Cell Signaling, 3504), and rabbit-anti-IRF3 (1:1000 ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... EZH2 (1:1000, Cell Signaling Technology, Cat# 5246) and SUZ12 (1:1000 ...
• Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter

  Marco Di Gioia, et al., bioRxiv - Immunology 2023

  Quote: ... NRF2 (1:1000, Cell Signaling Technology, Cat# 12721), phospho-ERK1/2 (Thr202/Tyr204 ...
• Axon guidance during CNS regeneration is required for specific brain innervation

  Celine Delpech, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-c-fos (Cell Signaling Technology, 1:200). The following day ...
• ATAD1 and the integrated stress response prevent clogging of TOM and damage caused by un-imported mitochondrial proteins

  John Kim, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-COXIV (1:1000, Cell Signaling Technology), mouse anti-eIF2α (1:1000 ...
• Desmosomal Cadherin Tension Loss in Pemphigus Vulgaris Mediated by the Inhibition of Active RhoA at Cell-Cell Adhesions

  Xiaowei Jin, et al., bioRxiv - Biophysics 2024

  Quote: ... E-cad antibodies (1:200, Cell Signaling Technologies), Alexa Fluor 647 (1:100 ...
• The ER Thioredoxin-Related Transmembrane Protein TMX2 Controls Redox-Mediated Tethering of ER-Mitochondria Contacts (ERMCS)

  Junsheng Chen, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-Flag (1:400, 14793, Cell Signaling); mouse anti-HA (1:200 ...
• The Rubicon-WIPI axis regulates exosome biogenesis during aging

  Kyosuke Yanagawa, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-ATG16L1 (Cell Signaling Technology, 8089, 1:1000), anti-PIK3C3 (Cell Signaling Technology ...
• The Rubicon-WIPI axis regulates exosome biogenesis during aging

  Kyosuke Yanagawa, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-PIK3C3 (Cell Signaling Technology, 3811, 1:1000), anti-WIPI1 (Sigma-Aldrich ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... Phospho-Akt (Thr308) (#4056, Cell signaling, 1:1000), Akt (#9272 ...
• Cell-matrix force transmission regulates the loss of naïve pluripotency in mouse embryonic stem cells

  Srivatsava Viswanadha, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit Sox1 1:200 (Cell Signaling, Cat#4194).
• CD28 Shapes T Cell Receptor Signaling by Regulating ZAP70 Activation and Lck Dynamics

  Kumarkrishna Raychaudhuri, et al., bioRxiv - Immunology 2024

  Quote: ... anti-PLCγ-1(Cell Signaling, Cat. No. 2822S), anti-Erk (Cell Signaling ...
• SRSF2 transcriptional function maintains genome integrity during cell division

  Rebecca E. Wagner, et al., bioRxiv - Cell Biology 2024

  Quote: ... total Pol II (1:1000, Cell Signaling Technologies), Pol II ser2 (1:1000 ...
• WEE1 kinase inhibition triggers severe chromosome pulverization in aneuploid cells

  Maria M. Haykal, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-CDK1 phosphorylated substrates (Cell signaling, 1/1000), rat anti-alpha-tubulin (ab6160 ...