Labshake search

701 - 750 of 10000+ citations for 2' Chloro 4 5 5 dimethyl 1 3 dioxan 2 yl butyrophenone since 2020

• miR-200 deficiency promotes lung cancer metastasis by activating cancer-associated fibroblasts

  Bin Xue, et al., bioRxiv - Cancer Biology 2020

  Quote: ... pErk1/2 pAb (Cell Signaling Technology, 4370), TTF1 (Nkx2.1 ...
• Targeting Chromatin Effector Pygo2 to Enhance Immunotherapy in Prostate Cancer

  Yini Zhu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-Erk1/2 (Cell Signaling Technology, 4370), p53 (Cell Signaling Technology ...
• Novel ERR pan-agonists ameliorate heart failure through boosting cardiac fatty acid metabolism and mitochondrial function

  Weiyi Xu, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... anti-ERK1/2 (Cell Signaling Technologies, 9102S), anti-LC3B (Cell Signaling Technologies ...
• Cross-activation of the FGF, TGF-β and WNT pathways constrains BMP4-mediated induction of the Totipotent state in mouse embryonic stem cells

  Thulaj Meharwade, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-ERK1/2 (137F5) (Cell Signaling 4695S) lot 28 ...
• Human cytomegalovirus UL7, miR-US5-1 and miR-UL112-3p inactivation of FOXO3a protects CD34⁺ hematopoietic progenitor cells from apoptosis

  Meaghan H. Hancock, et al., bioRxiv - Microbiology 2020

  Quote: ... P-ERK1/2 (Thr202/Tyr204, Cell Signaling), PARP (Cell Signaling) ...
• Targeting a broad spectrum of KRAS-mutant cancers by hyperactivation-induced cell death

  Johanna Lilja, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ERK1/2 (Cat. no. 91025, Cell Signaling), phospho-AKT (Ser473 ...
• Taxane chemotherapy leads to breast cancer dormancy escape by stromal injury mediated IL-6/MAP2K signaling

  Ramya Ganesan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rabbit ERK1/2 IgG (Cell Signaling Technology) (cat ...
• Double-targeted knockdown of miR-21 and CXCR4 inhibits malignant glioma progression by suppression of the PI3K/AKT and Raf/MEK/ERK pathways

  Feijiao Liu, Bo Yang, bioRxiv - Cancer Biology 2020

  Quote: ... and phospho-ERK1/2 (Cell Signaling Technology). The protein levels were digitalized using ImageJ 1.48 version (NIH ...
• The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation

  Leila Revollo, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti Erk1/2(Cell Signaling Technology, #4695), anti P-selectin (R&D Systems ...
• THEMIS is a priming substrate of non-receptor tyrosine phosphatase PTPN6/SHP1 and plays dual roles during T cell development

  Jiali Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-ERK1/2 (Cell Signaling Technology, 4377), anti-phospho-ERK1/2 (Thr202/Tyr204 ...
• Discovery of novel ID2 antagonists from pharmacophore-based virtual screening as potential therapeutics for glioma

  Genshen Zhong, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-MMP-2 (Cell Signaling Technology, #87809), anti-VEGFA (Cell Signaling Technology ...
• Oncogenic metabolic rewiring independent of proliferative control in human mammary epithelial cells

  Wentao Dong, et al., bioRxiv - Biochemistry 2022

  Quote: ... ERK1/2 (Cell Signaling, Cat. No. 9102) phospho-ERK1/2 (Cell Signaling ...
• Cellular protection from H₂O₂ toxicity by Fv-Hsp70. Protection via catalase and gamma-glutamyl cysteine synthase

  Chris Hino, et al., bioRxiv - Cell Biology 2023

  Quote: ... and polyclonal Nrf 2 (Cell Signaling 336495). All antibodies were used at 1:1000 dilution in blocking buffer ...
• Epigenomic Analyses Identify FOXM1 As a Key Regulator of Anti-Tumor Immune Response in Esophageal Adenocarcinoma

  Benjamin Ziman, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 2 μg FOXM1 antibody (Cell Signaling, 20459) was then added and incubated at 4 °C overnight on a rotating platform ...
• Nischarin negatively impacts ShcD-mediated tumor cell migration

  Rayan A. Hago, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-Erk1/2 (cst4695-Cell Signaling, USA), anti-Nischarin (ab204588-Abcam ...
• PML mutants resistant to arsenic induced degradation fail to generate the appropriate SUMO and ubiquitin signals required for RNF4 and p97 recruitment

  Ellis G. Jaffray, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-SUMO- 2 (Cell signaling 4971S), rabbit FK2 ubiquitin (Enzo BML-PW8810-0500) ...
• SHIP2 controls matrix mineralization by regulation of the RhoA/ROCK pathway and remodeling of the actin cytoskeleton

  Anais Fradet, Jamie Fitzgerald, bioRxiv - Cell Biology 2022

  Quote: ... Erk1/2 antibody (Cell Signaling Technologies #9107) 1/2000 ...
• MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer

  Olaf Klingbeil, et al., bioRxiv - Cancer Biology 2024

  Quote: ... p-LATS1/2 (T1079/T1041) (Cell Signaling, D57D3 ...
• Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon

  Daniela Araiza-Olivera, et al., bioRxiv - Cancer Biology 2024

  Quote: ... -total ERK1/2 (Cell Signaling Tech #9102), -GAPDH (#4138).
• Glioma-associated fibroblasts promote glioblastoma resistance to temozolomide through CCL2-CCR2 paracrine signaling

  Mingrong Zuo, et al., bioRxiv - Cancer Biology 2024

  Quote: ... total-ERK1/2 (Cell Signaling Technology #4696), Phospho-p38 MAPK (T180/Y182 ...
• Renal-Derived Human sPRR Does Not Increase Blood Pressure in High Fat Diet Mice

  Gertrude Arthur, et al., bioRxiv - Physiology 2024

  Quote: ... Aquaporin 2 (Cell Signaling Technology Inc, 3487) and GAPDH (Sigma Aldrich ...
• A high-throughput zebrafish screen identifies novel candidate treatments for Kaposiform Lymphangiomatosis (KLA)

  Ivan Bassi, et al., bioRxiv - Developmental Biology 2024

  Quote: ... phosphor-ERK1/2 (#4376, Cell Signaling, USA), and Podoplanin (M3619 ...
• Chitinase 3-like-1 (CHI3L1) Inhibits Innate Anti-Tumor and Tissue Remodeling Immune Responses by Regulating CD47-SIRPα and CD24-Siglec10-Mediated Phagocytosis

  Bing Ma, et al., bioRxiv - Immunology 2024

  Quote: ... and SHP-2 (Cell Signaling Technology, #3752) overnight at 4°C in TBST and 5% BSA ...
• Spatiotemporal Proteomics Deciphers Functional Selectivity of EGFR ligands

  Akihiro Eguchi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-Erk1/2 (#4695; Cell Signaling Technology) mouse anti-phospho-Erk1/2 (T202/T204 ...
• Multi-layered proteomics identifies insulin-induced upregulation of the EphA2 receptor via the ERK pathway and dependent on low IGF1R level

  Sarah Hyllekvist Jørgensen, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-ERK1/2 (Cell Signaling Technology); rabbit anti-Eph receptor A2 antibody (ab273118 and ab185156) ...
• Myocardin-related transcription factors regulate morphogenetic events in vertebrate embryos by controlling F-actin organization and apical constriction

  Keiji Itoh, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-Erk1/2 (9102, Cell Signaling), rabbit anti-phospho-Smad2 (3108S ...
• CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer

  Chunge Zhong, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ERK1/2 (Cell Signaling Technology, Cat# 137F5), p21 (Proteintech ...
• Lipid droplet targeting of ABHD5 and PNPLA3 I148M is required to promote liver steatosis

  Grace Teskey, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mek1/2 (Cell Signaling cat. No. S8727), AIF (Cell Signaling cat ...
• Testicular sex cord–stromal tumors in mice with constitutive activation of PI3K and loss of Pten

  Marija Dinevska, et al., bioRxiv - Cancer Biology 2024

  Quote: ... phospho-Erk1/2 (Cell Signaling Technologies 4370), phospho-Akt (Cell Signaling Technologies 4060 ...
• Electron transport chain inhibition increases cellular dependence on purine transport and salvage

  Zheng Wu, et al., bioRxiv - Biochemistry 2023

  Quote: ... The membranes were washed with PBS 3 times for 5 minutes and then incubated with horseradish peroxidase conjugated secondary antibody (Cell Signaling Technology, 7074, 7076) in 5% non-fat milk in PBST at room temperature for 1 hour ...
• Development of follicular dendritic cells in lymph nodes depends on retinoic acid mediated signaling

  Jasper J. Koning, et al., bioRxiv - Immunology 2020

  Quote: ... Cells were fixed with 4% paraformaldehyde for 5 min and subsequently permeabilized with 0.2% Triton-X and stained with anti-relB (Cell Signaling Technology, Danvers, USA) followed by goat-anti-rabbit Alexa 546 (Invitrogen) ...
• Alternative mRNA splicing controls the functions of the histone H3K27 demethylase UTX/KDM6A

  Omid Fotouhi, et al., bioRxiv - Biochemistry 2023

  Quote: ... The membrane was blocked in 5% skimmed milk and incubated overnight at 4°C with primary antibodies for UTX (Cell Signaling Technologies #33510), GFP (JL-8 ...
• Sustained experimental activation of FGF8/ERK in the developing chicken spinal cord reproducibly models early events in ERK-mediated tumorigenesis

  Axelle Wilmerding, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-phospho-p44/42 MAPK (ERK1/2) (Thr202/Tyr204) 1:250 (Cell signaling #9101), rabbit anti-SOX2 1:500 (AB5603 Merck Millipore) ...
• MicroRNA-dependent inhibition of PFN2 orchestrates ERK activation and pluripotent state transitions by regulating endocytosis

  Carolyn Sangokoya, Robert Blelloch, bioRxiv - Developmental Biology 2020

  Quote: ... Phospho-p44/42 Erk1/2 Thr202/Tyr204 at 1:1000 dilution (Cell Signaling Technology, 4370), and p44/42 Erk1/2 at 1:1000 dilution (Cell Signaling Technology ...
• Reversal of β-amyloid induced microglial toxicity in vitro by activation of Fpr2/3

  Edward S. Wickstead, et al., bioRxiv - Neuroscience 2020

  Quote: ... or superoxide dismutase 2 (SOD2; rabbit monoclonal, 1:1000, Cell Signaling Technology, Leiden, The Netherlands) in Tris-buffer saline solution containing 0.1% Tween-20 and 5% (w/v ...
• Negative durotaxis: cell movement toward softer environments

  Aleksi Isomursu, et al., bioRxiv - Biophysics 2020

  Quote: ... rbt anti-p-ERK1/2 (T202/Y204) (Cell Signaling Technology, 4370, 1:1000 for WB), ms anti-YAP (Santa Cruz Biotechnology ...
• Kir6.2-containing K_ATP channels are necessary for glucose dependent increases in amyloid-beta and Alzheimer’s-related pathology

  John Grizzanti, et al., bioRxiv - Neuroscience 2022

  Quote: ... 2° antibody conjugated with HRP specific to either (1:3,000) goat anti-rabbit (Cell Signaling) or (1:3,000 ...
• Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer progression

  Jason J. Northey, et al., bioRxiv - Cancer Biology 2022

  Quote: ... phospho-p44/42 MAPK (ERK1/2) (T202/Y204) (Cell Signaling Technology, Cat. #: 9101, 1:200), NFκB p65 (D14E12 ...
• Purinergic receptor P2RY14 cAMP signaling regulates EGFR-driven Schwann cell precursor self-renewal and nerve tumor initiation in neurofibromatosis

  Jennifer Patritti-Cram, et al., bioRxiv - Neuroscience 2021

  Quote: ... P44/42 MAPK (Erk1/2) (137F5) rabbit mAB (1:1000, Cell Signaling Technologies, Cat#: 4695S).
• Biphasic Response of Protein Kinase A to Cyclic Adenosine Monophosphate Triggers Distinct Epithelial Phenotypes

  João Pedro Fonseca, et al., bioRxiv - Systems Biology 2020

  Quote: ... F(ab’)2 Fragment (Alexa Fluor® 488 Conjugate) (Cell Signaling Technology #4412, 1:1000).
• Biphasic Response of Protein Kinase A to Cyclic Adenosine Monophosphate Triggers Distinct Epithelial Phenotypes

  João Pedro Fonseca, et al., bioRxiv - Systems Biology 2020

  Quote: ... anti-p44/42 MAPK (Erk1/2) (L34F12) Mouse mAb (Cell signaling technology ##4696, 1:2000), anti-Phospho-p38 MAPK (Thr180/Tyr182 ...
• Long-term non-invasive drug treatments for adult zebrafish

  Yuting Lu, E. Elizabeth Patton, bioRxiv - Cancer Biology 2021

  Quote: ... total p44/42 MAPK (ERK1/2) primary antibody (1:200, rabbit, Cell Signaling Technologies #9102), and Alexa-fluor 488 secondary antibody (1:1000 ...
• KRAS G12D can be targeted by potent salt-bridge forming inhibitors

  Zhongwei Mao, et al., bioRxiv - Cancer Biology 2021

  Quote: ... slides were incubated with primary antibodies against pERK1/2 (1:200, Cell Signaling Technology, 4370), cleaved Caspase-3 (1:200 ...
• Murine gammaherpesvirus 68 ORF45 stimulates B2 retrotransposon and pre-tRNA activation in a manner dependent on mitogen-activated protein kinase (MAPK) signaling

  Azra Lari, Britt A. Glaunsinger, bioRxiv - Microbiology 2022

  Quote: ... anti-phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) antibody (Cell Signaling #9101, 1:1000), anti-Brf1polyclonal antibody (Bethyl ...
• Ca²⁺-driven cytoplasmic backflow secures spindle position in fertilized mouse eggs

  Takaya Totsuka, Miho Ohsugi, bioRxiv - Cell Biology 2024

  Quote: ... rabbit anti-phospho-myosin light chain 2 (Ser19) (pMLC) (1:100, Cell Signaling Technology #3671), for 2 hours ...
• Endosomal LRBA regulates the endo-lysosomal pathway

  Viktória Szentgyörgyi, et al., bioRxiv - Immunology 2024

  Quote: ... mouse monoclonal anti p44/42 MAPK (Erk1/2) (L334F10) antibody (#4696, Cell Signaling, 1:2000), rabbit polyclonal anti phospho-p44/42 MAPK (Erk1/2 ...
• Endosomal LRBA regulates the endo-lysosomal pathway

  Viktória Szentgyörgyi, et al., bioRxiv - Immunology 2024

  Quote: ... mouse monoclonal anti p44/42 MAPK (Erk1/2) (L334F10) antibody (#4696, Cell Signaling, 1:2000), rabbit polyclonal anti phospho-p44/42 MAPK (Erk1/2 ...
• Influence of myosin regulatory light chain and myosin light chain kinase on hair cells of the inner ear

  Ryohei Oya, et al., bioRxiv - Biophysics 2023

  Quote: ... anti-phospho-myosin light chain 2 (3671; Cell Signaling Technology, Danvers, MA, USA; 1:50); Alexa Fluor 488-labeled secondary antibody (Thermo Fisher Scientific ...
• Differentiation signals from glia are fine-tuned to set neuronal numbers during development

  Anadika R. Prasad, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (1:100, Cell Signaling #9101), chicken anti-RFP (1:500 ...
• HD-PTP/PTPN23 hypomorphic mice display lipodystrophy

  Brian A. Davies, et al., bioRxiv - Cell Biology 2022

  Quote: ... total-p42/44 MAPK (ERK1/2) 3A7 mouse monoclonal antibody (1:2000, 9107, Cell Signaling), p-AKT-S473 D9E rabbit monoclonal antibody (1:1000 ...