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7251 - 7300 of 10000+ citations for 7 CHLORO 1 METHYL 1H PYRAZOLO 4 3 B PYRIDINE since 2019

• Monocarboxylate transporter 1 in Schwann cells is critical for maintenance of sensory nerve myelination during aging

  Mithilesh Kumar Jha, et al., bioRxiv - Neuroscience 2019

  Quote: ... c-Jun (clone 60A8; Cell Signaling Technology; 1:300) or CD271 (p75NTR ...
• Loss of function mutation of mouse Snap29 on a mixed genetic background phenocopy abnormalities found in CEDNIK and 22q11.2 Deletion Syndrome patients

  Vafa Keser, et al., bioRxiv - Developmental Biology 2019

  Quote: ... An anti-rabbit secondary antibody (1:5000, Cell Signaling) was used for both SNAP29 and beta-actin ...
• Cell signaling coordinates global Polycomb Repressive Complex 2 recruitment and gene expression in murine embryonic stem cells

  Mohammad B. Aljazi, et al., bioRxiv - Genetics 2020

  Quote: ... rabbit anti-JARID2 antibody (1:100, Cell Signaling Technology), rabbit anti-RING1B antibody (1:100 ...
• Defined neuronal populations drive fatal phenotype in Leigh Syndrome

  Irene Bolea, et al., bioRxiv - Neuroscience 2019

  Quote: ... p-S6(Ser235/236) (Cell signaling, rabbit, 1:2,000), β-actin (Sigma ...
• Aicardi-Goutières Syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer

  Sarah K Deasy, et al., bioRxiv - Cancer Biology 2019

  Quote: ... NF-κB1 p105/p50 (1:1000; Cell Signaling #12540), NF-κB2 p100/p52 (1:1000 ...
• Aicardi-Goutières Syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer

  Sarah K Deasy, et al., bioRxiv - Cancer Biology 2019

  Quote: ... NF-κB2 p100/p52 (1:1000; Cell Signaling #4882), RELB (1:1000 ...
• Fibroblast growth factor 9 stimulates neurite outgrowth through NF-kB signaling in striatal cell Huntington’s disease models

  Issa Olakunle Yusuf, et al., bioRxiv - Neuroscience 2020

  Quote: ... and NF-kB/p65 (Cell signaling; 1:250 dilution). Afterward ...
• Lineage reversion drives WNT independence in intestinal cancer

  Teng Han, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-Smad4 (1:1000, Cell Signaling Technologies, #46535), rabbit anti-Smad2/3 (1:1000 ...
• Lineage reversion drives WNT independence in intestinal cancer

  Teng Han, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-YAP (1:1000, Cell Signaling Technologies, #14074), rabbit anti-YAP/TAZ (1:1000 ...
• Lineage reversion drives WNT independence in intestinal cancer

  Teng Han, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-Runx2 (1:1000, Cell Signaling Technologies, #12556), mouse anti-E-Cadherin (1:1000 ...
• Lineage reversion drives WNT independence in intestinal cancer

  Teng Han, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-Junb (1:1000, Cell Signaling Technologies, #3753), rabbit anti-ETS-1 (1:1000 ...
• Lineage reversion drives WNT independence in intestinal cancer

  Teng Han, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-GAPDH (1:1000, Cell Signaling Technologies, #5174), rabbit anti-Cyclophilin B (1:1000 ...
• Genetic risk of cholangiocarcinoma is linked to the autophagy gene ATG7

  Stephanie U. Greer, et al., bioRxiv - Genomics 2019

  Quote: ... LC3B (clone D11, Cell Signaling Technology 3868; 1:250) and p62 (Enzo PW9860 ...
• Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma

  Laurie Herviou, et al., bioRxiv - Cancer Biology 2019

  Quote: ... and rabbit anti-Histone H4 (1:1000, Cell Signaling). Membranes were then incubated with the appropriate horseradish peroxidase (HRP)-conjugated secondary antibodies ...
• MCT4 is a high affinity transporter capable of exporting lactate in high-lactate environments

  Y Contreras-Baeza, et al., bioRxiv - Physiology 2019

  Quote: ... mouse anti- β-actin (1:2,000; 8H10D10, Cell Signaling), peroxidase-conjugated antirabbit (1:20,000 ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-HA (rabbit, 1:1000) (#3724, Cell Signaling Technology), anti-MARCH5 (rabbit ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-MCL1 (rabbit, 1:1000) (#5453, Cell Signaling Technology), anti-MCL1 (mouse ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-p27 (rabbit, 1:1000) (#3686, Cell Signaling Technology), anti-p53 (mouse ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-p62 (rabbit, 1:1000) (#5114, Cell Signaling Technology), anti-PARP (rabbit ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-PARP (rabbit, 1:1000) (#9532, Cell Signaling Technology), anti-phospho-eIF2α Ser51 (rabbit ...
• Ubiquitin Ligase MARCH5 Regulates Apoptosis through Mediation of Stress-Induced and NOXA-Dependent MCL1 Degradation

  Seiji Arai, Sen Chen, Lisha Xie, Steven P. Balk, bioRxiv - Cancer Biology 2020

  Quote: ... anti-PUMA (rabbit, 1:500) (#12450, Cell Signaling Technology), or anti-vinculin (mouse ...
• Invariant chain regulates endosomal fusion and maturation through the SNARE Vti1b

  Dominik Frei, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-Rab7a (2094S, 1:500) from Cell Signaling; rabbit anti-GFP (ab6556 ...
• Impaired peroxisomal import in Drosophila hepatocyte-like cells induces cardiac dysfunction through the pro-inflammatory cytokine Upd3

  Kerui Huang, et al., bioRxiv - Physiology 2019

  Quote: ... anti-P-JNK (Cell Signaling Technology, #9255, 1:2000), anti-JNK (Cell Signaling Technology ...
• Mitochondrial dysfunction is signaled to the integrated stress response by OMA1, DELE1 and HRI

  Xiaoyan Guo, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-OMA1 (Cell Signaling Technologies #95473, 1:1000), rabbit anti-LonP1 (Cell Signaling Technologies #56266 ...
• Mitochondrial dysfunction is signaled to the integrated stress response by OMA1, DELE1 and HRI

  Xiaoyan Guo, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-LonP1 (Cell Signaling Technologies #56266, 1:1000), rabbit anti-Hsp60 (Cell Signaling Technologies #12165 ...
• Mitochondrial dysfunction is signaled to the integrated stress response by OMA1, DELE1 and HRI

  Xiaoyan Guo, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-Hsp60 (Cell Signaling Technologies #12165, 1:1000), mouse OXPHOS cocktail (anti-ATP5A ...
• Mitochondrial dysfunction is signaled to the integrated stress response by OMA1, DELE1 and HRI

  Xiaoyan Guo, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-AIF (Cell Signaling Technologies #5318, 1:1000). Antibodies failed to detect DELE1 include ...
• Lineage reversion drives WNT independence in intestinal cancer

  Teng Han, et al., bioRxiv - Cancer Biology 2020

  Quote: ... rabbit anti-KRT20 (1:200, Cell Signaling Technologies, #13063), rabbit anti-Lysozyme (1:1000 ...
• DYNLL1 mis-splicing is associated with replicative genome instability in SF3B1 mutant cells

  Annie S. Tam, et al., bioRxiv - Cell Biology 2021

  Quote: ... p-CHK2 (Th468) (1:1000, Cell Signaling cat#C13C1), GAPDH (1:3000 ...
• DYNLL1 mis-splicing is associated with replicative genome instability in SF3B1 mutant cells

  Annie S. Tam, et al., bioRxiv - Cell Biology 2021

  Quote: ... p-CHK1 (Ser345) (1:1000, Cell Signaling cat#133D3), p-ATM (1:500 ...
• DYNLL1 mis-splicing is associated with replicative genome instability in SF3B1 mutant cells

  Annie S. Tam, et al., bioRxiv - Cell Biology 2021

  Quote: ... p-ATR (Ser428) (1:1000, Cell Signaling cat#2853), p-CHK1 (Ser345 ...
• EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in developing neurons

  SS Parker, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit monoclonal anti-VASP (Cell Signaling #3132, 1:500), rabbit polyclonal anti-MTSS1 (Thermo ...
• Loss of Kallmann syndrome-associated gene WDR11 disrupts primordial germ cell development by affecting canonical and non-canonical Hedgehog signalling

  Jiyoung Lee, et al., bioRxiv - Genetics 2020

  Quote: ... phospho-Creb (Rabbit IgG, 1:200, Cell Signaling, 9198), Wdr11 (rabbit IgG ...
• Dynamic proteomics profiling of Legionella pneumophila infection unveils modulation of the host mitochondrial stress response pathway

  Julia Noack, et al., bioRxiv - Cell Biology 2020

  Quote: ... Phospho-c-Jun (Ser73) 1:1000 (Cell Signaling Technology). Membranes were washed three times with PBS-T and incubated with Goat Anti-Mouse IgG (H+L ...
• Epithelial-mesenchymal plasticity through loss of CTCF motif accessibility and protein expression

  Kelsey S. Johnson, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-SMC3 (#5696, monoclonal rabbit, 1:1000, Cell Signaling), anti-YY1 (#46395S ...
• Epithelial-mesenchymal plasticity through loss of CTCF motif accessibility and protein expression

  Kelsey S. Johnson, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-YY1 (#46395S, monoclonal rabbit, 1:1000, Cell Signaling), anti-ZEB1 (21544-1-AP ...
• Ciliopathic micrognathia is caused by aberrant skeletal differentiation and remodeling

  Christian Louis Bonatto Paese, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and Phospho-Histone H3 (1:200, Cell Signaling 9706) primary antibodies were used ...
• Post-entry, spike-dependent replication advantage of B.1.1.7 and B.1.617.2 over B.1 SARS-CoV-2 in an ACE2-deficient human lung cell line

  Daniela Niemeyer, et al., bioRxiv - Microbiology 2021

  Quote: ... rabbit anti-tubulin (Cell Signaling Technology, 2144S, 1:1000). Secondary antibodies conjugated to Alexa680/800 fluorescent dyes were used for detection and quantification by Odyssey Infrared Imaging System (LI-COR Biosciences) ...
• WWP1 deficiency protects from cardiac remodeling induced by simulated microgravity

  Guohui Zhong, et al., bioRxiv - Physiology 2021

  Quote: ... or DVL2 antibody (1/100, Cell Signaling Technology, #3224S). After three times washes in PBS ...
• Proteome and functional decline as platelets age in the circulation

  Harriet E. Allan, et al., bioRxiv - Cell Biology 2021

  Quote: ... horseradish peroxidase-linked antibody (1:10,000, Cell Signaling Technology) for 1 hour ...
• Soft limbal niche maintains stem cell compartmentalization and function through YAP

  Swarnabh Bhattacharya, et al., bioRxiv - Cell Biology 2021

  Quote: ... and rabbit anti-GAPDH (1:1000, Cell signaling, #2118).
• UCHL1 inhibited by A1 astrocytes facilitates aggregates clearance to promote neural stem cells activation after spinal cord injury

  Lu Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... Neurofilament 200 (NF200; 1:300; Cell Signaling Technology, CST), 5-hydroxytryptamine (5HT ...
• Cocaine Triggers Glial-Mediated Synaptogenesis

  Junshi Wang, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-NeuN (1:500, rabbit, Cell Signaling Technology, #12941). After incubation with the primary antibody ...
• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Htt 1:1000 (Cell Signaling, cat n°2773S) and anti-myc (custom produced from 9E10 hybridoma) ...
• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-LC3 1:1000 (Cell Signaling, Cat. n° 2775S), anti-p62 1:1000 (Abcam ...
• Identifying Isl1 genetic lineage in the developing olfactory system and in GnRH-1 neurons

  Ed Zandro M. Taroc, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit-α-phospho-Histone-H3 (1:400, Cell Signaling), goat-α-Sox2 (1:400 ...
• Activity-regulated cytoskeleton-associated protein (Arc/Arg3.1)-mediated plasticity in the paraventricular thalamic nucleus promotes a fundamental adaptation to stress

  Brian F. Corbett, et al., bioRxiv - Neuroscience 2021

  Quote: ... and rabbit anti-HA (C29F4, 1:250, Cell Signaling). Alexa Fluor ® secondary antibodies were used at a concentration of 1:200 (see supplemental information).
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Phospho-c-Jun (Ser63) (Cell Signaling, 9261s, 1:1000), c-Jun (Cell Signaling ...
• Chlamydia coinfection inhibits HPV-induced safeguards of the cellular and genomic integrity in patient-derived ectocervical organoids

  Stefanie Koster, et al., bioRxiv - Cancer Biology 2021

  Quote: ... mouse-anti-Rb (4H1) (1:2000, Cell Signaling, # 9309), rabbit-anti-pRb (Ser807/811 ...
• Notch signaling determines cell-fate specification of the two main types of vomeronasal neurons of rodents

  Raghu Ram Katreddi, et al., bioRxiv - Developmental Biology 2021

  Quote: ... *Rabbit anti-Ki67 (1:1000, D3B5, Cell signaling Tech), *Mouse anti-Ki67 (1:500 ...