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6201 - 6250 of 10000+ citations for 7 hydroxy 1H 1 2 4 triazolo 1 5 a pyrimidin 5 one since 2019

• Nucleus translocation of tRNA synthetase mediates late integrated stress response

  Na Wei, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit monoclonal EEF1A1 (1:1000, Cell Signaling Technology, #3586), goat polyclonal RAE1 (1:1000 ...
• Nucleus translocation of tRNA synthetase mediates late integrated stress response

  Na Wei, et al., bioRxiv - Molecular Biology 2020

  Quote: ... mouse monoclonal HDAC3 (1:1000, Cell Signaling Technology, #3949), mouse monoclonal RbAp46 (1:1000 ...
• Nucleus translocation of tRNA synthetase mediates late integrated stress response

  Na Wei, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit polyclonal eIF2α (1:1000, Cell Signaling Technology, #9722), rabbit monoclonal ATF-4 (1:1000 ...
• PIP₂-dependent coupling of voltage sensor and pore domains in K_v7.2

  Shashank Pant, et al., bioRxiv - Biophysics 2021

  Quote: ... anti-α-tubulin (Cell Signaling #2144, 1:1000 dilution), anti-β-tubulin (Cell Signaling #2146 ...
• Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations

  H. Nayanga Thirimanne, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Rabbit anti-H3K4me2 (1:100, Cell Signaling Tech 9725) and (Rabbit normal IgG (1:50 ...
• Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations

  H. Nayanga Thirimanne, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-H3K27me3 (1:100, Cell Signaling Technologies Cat#9733S), Rabbit c-Jun (1:25 ...
• Hypoxia-directed tumor targeting of CRISPR/Cas9 and HSV-TK suicide gene therapy using lipid nanoparticles

  Alicia Davis, Kevin V. Morris, Galina Shevchenko, bioRxiv - Cancer Biology 2021

  Quote: ... anti-Histone H3 (1:10,0000; Cell Signaling Technologies 14269), anti-mouse IgG HRP conjugate (1:10,000 ...
• mTOR inhibition enhances delivery and activity of antisense oligonucleotides in uveal melanoma cells

  Shanna Dewaele, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and anti-mouse (7076P2, Cell Signaling, 1:10000 dilution) antibodies were used as secondary antibodies ...
• TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

  Engin Demirdizen, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-phospho-Akt (Cell Signaling #4060, 1:2000); rabbit anti-Vimentin (Cell Signaling #3932 ...
• TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

  Engin Demirdizen, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-phospho-FAK (Cell Signaling #8556, 1:1000); mouse anti-Flag (Sigma #F1804 ...
• TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

  Engin Demirdizen, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-cleaved-PARP (Cell Signaling #5625, 1:400). Secondary antibodies used for IF staining were ...
• TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

  Engin Demirdizen, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-cleaved-CASP3 (Cell Signaling #9664, 1:500); rabbit anti-cleaved-PARP (Cell Signaling #5625 ...
• Inhibition of Metastatic Uveal Melanoma Cell Proliferation by the Histone Deacetylase 6 Inhibitor, Ricolinostat, is Linked to Altered Microphthalmia-associated Transcription Factor and Phospho-ERK Expression

  Husvinee Sundaramurthi, et al., bioRxiv - Cancer Biology 2021

  Quote: ... acetylated α-tubulin (1:1000; #5335, Cell Signaling Technology), MITF (1:1000 ...
• Inhibition of Metastatic Uveal Melanoma Cell Proliferation by the Histone Deacetylase 6 Inhibitor, Ricolinostat, is Linked to Altered Microphthalmia-associated Transcription Factor and Phospho-ERK Expression

  Husvinee Sundaramurthi, et al., bioRxiv - Cancer Biology 2021

  Quote: ... HRP-linked Antibody (1:3000; #7076s, Cell Signaling Technology) were used as secondary antibodies ...
• Haploinsufficient tumour suppressor PRP4K is negatively regulated during epithelial-to-mesenchymal transition

  Livia E. Clarke, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-claudin-1 (Cell Signaling [Danvers, MA, USA], 13255) (1:1000) ...
• CCR5 closes the temporal window for memory linking

  Yang Shen, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-cFos (Cell Signaling, 9F6, #2250, 1:500), and rabbit anti-P2Y12 (AnaSpec ...
• Phosphatidylserine binding regulates TIM-3 effects on T cell receptor signaling

  Courtney M. Smith, et al., bioRxiv - Biochemistry 2021

  Quote: ... and anti-PD-1 (Cell Signaling Technology, catalog #86163). For TCR stimulation ...
• Glutamine deficiency in solid tumors confers resistance to ribosomal RNA synthesis inhibitors

  Melvin Pan, et al., bioRxiv - Cancer Biology 2021

  Quote: ... phospho-S6 (S235/236) (1:1000, Cell Signaling Technology), S6 (1:1000 ...
• Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform

  Santiago Naranjo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-HMGA2 (1:400, Cell Signaling Technology, #8179). For IHC staining of lung and organoid sections ...
• Nucleotide Biosynthesis Links Glutathione Metabolism to Ferroptosis Sensitivity

  Amy Tarangelo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and RRM2 (Cat # 65939, Cell Signaling Technologies, 1:500). Membranes were washed three times for 10 min each in Tris buffered saline (Cat# 0788 ...
• Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

  Patrícia M. R. Pereira, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-pCREB 1:1,000 (Cell Signaling Technology, 9198S).
• Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

  Patrícia M. R. Pereira, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-ubiquitin 1:1,000 (Cell Signaling Technology, 3933S), mouse anti-ERK 1:100 (Invitrogen ...
• Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

  Patrícia M. R. Pereira, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-CREB 1:1,000 (Cell Signaling Technology, 9197S), rabbit anti-pCREB 1:1,000 (Cell Signaling Technology ...
• Caveolin-1 temporal modulation enhances trastuzumab and trastuzumab-drug conjugate efficacy in heterogeneous gastric cancer

  Patrícia M. R. Pereira, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-AKT 1:1,000 (Cell Signaling Technology, 9272S), rabbit anti-pAKT ...
• Widespread reorganisation of the regulatory chromatin landscape facilitates resistance to inhibition of oncogenic ERBB2 signalling

  Samuel Ogden, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-phospho-ERK (Cell Signaling Technologies, 9106S, 1:2,000), anti-AKT (Cell Signaling Technologies ...
• The oncogenic Runx3–Myc axis defines p53-deficient osteosarcomagenesis

  Shohei Otani, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p53 (DO-1, MBL, 1C12, Cell Signaling Technology), anti-p21 (EPR3993 ...
• Widespread reorganisation of the regulatory chromatin landscape facilitates resistance to inhibition of oncogenic ERBB2 signalling

  Samuel Ogden, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-phospho-AKT (Cell Signaling Technologies, 4060S, 1:2,000), anti-HNF4A (R&D Systems ...
• Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243A>G mtDNA mutation

  Chih-Yao Chung, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-p-S6 (1:3000, Cell Signaling Technology #4858), anti-S6 (1:3000 ...
• Extracellular vesicles from neuronal cells promote neural induction of mESCs through cyclinD1

  Lu Song, Xinran Tian, Randy Schekman, bioRxiv - Cell Biology 2021

  Quote: ... anti-HA (1:1,000; Cell Signaling Technology, Danvers, MA).
• BRAF inhibitors reprogram cancer-associated fibroblasts to drive matrix remodeling and therapeutic escape in melanoma

  Tianyi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cleaved caspase-3 (Cell Signaling Technology, 9661, 1:200), and POSTN (Invitrogen ...
• MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions

  Elyne Backx, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-phospho-ERK (9101S, Cell Signaling Technology, 1/1000) and anti-total ERK (4695 ...
• BRAF inhibitors reprogram cancer-associated fibroblasts to drive matrix remodeling and therapeutic escape in melanoma

  Tianyi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p-GSK-3β (Cell Signaling Technology, 5558, 1:2000), GSK-3β (Cell Signaling Technology ...
• BRAF inhibitors reprogram cancer-associated fibroblasts to drive matrix remodeling and therapeutic escape in melanoma

  Tianyi Liu, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p-β-catenin (Cell Signaling Technology, 9561, 1:500), β-actin (Cell Signaling Technology ...
• UFMylation regulates translational homeostasis and cell cycle progression

  Igor A. Gak, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit polyclonal eIF4A1 (Cell Signaling Technologies, 2490, 1:1000), eIF4B (1F5 ...
• Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis

  Andrew S. Riching, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-total Smad2/3 (Cell Signaling 8685S, 1:1000), anti-HA (Rockland 600-401-384 ...
• The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates

  Mena Abdel-Nour, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-cleaved PARP (#9546, Cell Signaling, 1/1,000), rabbit anti-GFP (#ab290 ...
• Phosphatidylinositol 4-kinase III beta regulates cell shape, migration and Focal Adhesion number

  Patricia Bilodeau, et al., bioRxiv - Cell Biology 2020

  Quote: ... tubulin (1:1000, Cell Signaling Technology 3873; Whitby, Canada), mouse α-FAK (1:200 Thermo Fisher #396500) ...
• TRIP6 is required for tension at adherens junctions

  Srividya Venkatramanan, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-VASP (1:100; Cell Signaling Technology #3132S), mouse anti-ZO-1 (1:1000 ...
• TRIP6 is required for tension at adherens junctions

  Srividya Venkatramanan, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-VASP (1:1000; Cell Signaling Technology #3132S) and rabbit-myosin light chain (1:1000 ...
• Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

  Saskia Hoffmann, et al., bioRxiv - Cell Biology 2020

  Quote: ... Cleaved Caspase-3 (Asp175, 9661, Cell Signaling (1:1,000)) ...
• Lysosomal nucleotide metabolism regulates ER proteostasis through mTOR signaling

  Keng Hou Mak, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-S6K (1:1000, cat# 9202, Cell Signaling Technology), and β-actin (1:5,000 ...
• AdipoR2 is Essential for Membrane Lipid Homeostasis in Response to Dietary Saturated Fats

  Ranjan Devkota, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit monoclonal anti-GAPDH (14C10, 1:1000, Cell Signaling).
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... p-c-Jun S63 (#9261S, 1:1000, Cell Signaling), c-Jun (#9165S ...
• FCHSD2 Controls Oncogenic ERK1/2 Signaling Outcome by Regulating Endocytic Trafficking

  Guan-Yu Xiao, Sandra L. Schmid, bioRxiv - Cell Biology 2020

  Quote: ... p-MET Y1234/1235 (#3077S, 1:1000, Cell Signaling), MET (#8198S ...
• Subcellular localization of glypican-5 associates with dynamic cell motility and cell communication of the human mesenchymal stem cell line U3DT

  Masao Takeuchi, et al., bioRxiv - Cell Biology 2019

  Quote: ... Anti-FGFR-1 (D8E4) XP Rabbit mAb (Cell Signaling). Alexa Fluor 488 conjugated-anti-mouse IgG(H+L) ...
• Widespread non-apoptotic activation of Drosophila Caspase-2/9 limits JNK signaling, macrophage proliferation, and growth of wound-like tumors

  Derek Cui Xu, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-HA-tag (1:1000, Cell Signaling, RRID:AB_1549585), rabbit anti-Phospho-histone H3 (1:100 ...
• Inhibitors of the Bub1 spindle assembly checkpoint kinase: Synthesis of BAY-320 and comparison with 2OH-BNPP1

  Ilma Amalina, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-GFP (Cell Signaling cat#2956, 1:1000); sheep anti-Tao154 (1:1,000) ...
• SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors

  Giulio Giuliani, et al., bioRxiv - Cell Biology 2020

  Quote: ... and rabbit Ki-67 1:400 (Cell Signaling 9129). For CD140a immunolabelling ...
• Amelioration of DSS-induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22

  Suhyun Kim, et al., bioRxiv - Immunology 2021

  Quote: ... Mouse anti-STAT3 (1:1000, Cell Signaling Technology, USA), mouse anti-pSTAT3 (Tyr705 ...
• Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

  Allison K. Meyers, et al., bioRxiv - Immunology 2021

  Quote: ... p-TBK1 (Ser172) ( Cell Signaling, no. CST5483; 1:1000); and β-actin (Sigma-Aldrich ...