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551 - 600 of 2670 citations for 2' 3' Dimethyl 3 2 5 dimethylphenyl propiophenone since 2020

• Single Cell Resolution Spatial Mapping of Human Hematopoiesis Reveals Aging-Associated Topographic Remodeling

  Aleksandr Sarachakov, et al., bioRxiv - Systems Biology 2023

  Quote: ... 3) Opal 570/anti-CD117 (1:100, D3W6Y, Cell Signaling), 4 ...
• Steroid Receptor Coactivator-3 is a Key Modulator of Regulatory T Cell-Mediated Tumor Evasion

  Sang Jun Han, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Slices were incubated with anti-SRC-3 (Cell Signaling Technology Cat# 2126 ...
• Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

  Tiantian Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and Histone 3 (1:1,000, Cell Signaling Technology, Cat# 5427) and then were incubated with horseradish peroxidase-conjugated secondary antibodies ...
• High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1

  William Bolland, et al., bioRxiv - Microbiology 2023

  Quote: ... and rabbit anti-cleaved caspase-3 (D175; Cell Signaling Technology) and imaged using the LSM-700 confocal microscope (Zeiss).
• Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks

  Quen J. Cheng, et al., bioRxiv - Immunology 2023

  Quote: ... pIRF-3 (Rabbit IgG, 1:1000, Cell Signaling Technology 4947), p65(RelA ...
• Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor

  Patricia D.B. Tiburcio, et al., bioRxiv - Cancer Biology 2024

  Quote: ... cleaved Caspase-3 (Cell Signaling Technology 9664, RRID:AB_2070042; 1:1,000), Caspase-7 (Cell Signaling Technology 12827 ...
• PTBP1 mediates Sertoli cell actin cytoskeleton organization by regulating alternative splicing of actin regulators

  Yuexi Wang, et al., bioRxiv - Molecular Biology 2024

  Quote: ... rabbit anti-Cleaved CASPASE 3 (Cell Signaling Technology, Cat# 9661), rat anti-GCNA1 (DSHB ...
• Homologous recombination promotes mitotic death to suppress the innate immune response

  Radoslaw Szmyd, et al., bioRxiv - Cell Biology 2024

  Quote: ... Cleaved Caspase-3 (Asp175, Cell Signaling Technology, 9661, 1:500), Cleaved Caspase-8 (Asp384 ...
• Sphingosine kinase 1 is integral for elastin deficiency-induced arterial hypermuscularization

  Junichi Saito, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit anti-cleaved caspase-3 (Cell signaling, 9664; 1:250), rabbit anti-EGR1 (Cell signaling ...
• MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability

  Neel Jasani, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Cleaved Caspase 3 (1:200, Cell Signaling Technologies, Cat. # 9661) and Ki-67 (1:100 ...
• Dual targeting of KDM1A and antioxidants is an effective anticancer strategy

  Shaila Mudambi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... All antibodies (Table 3) were purchased from Cell Signaling Technologies.
• Depletion of TDP-43 exacerbates tauopathy-dependent brain atrophy by sensitizing vulnerable neurons to caspase 3-mediated endoproteolysis of tau in a mouse model of Multiple Etiology Dementia

  Meghraj S Baghel, et al., bioRxiv - Neuroscience 2024

  Quote: ... and cleaved caspase 3 (1:1000; 5A1E; Cell Signaling Technology). Immunoblots were developed using enhanced chemiluminescence method (Millipore Corp. ...
• Correction of RBFOX1 deficit rescues Huntington’s disease mis-splicing and pathology

  David Lozano-Muñoz, et al., bioRxiv - Neuroscience 2024

  Quote: ... and rabbit Cleaved caspase-3 (1:100, Cell Signaling, 9661) for mouse samples ...
• Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience

  Carron Charline, et al., bioRxiv - Neuroscience 2024

  Quote: ... or rabbit anti-Caspase-3 (1:500, Cell Signaling 9579) overnight at 4°C ...
• Dynamic Interplay of Autophagy and Membrane Repair During Mycobacterium tuberculosis Infection

  Jacques Augenstreich, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Galectin-3 antibody (Cell signaling technology D4I2R XP(R)) ...
• Association of cerebellar inflammation and neurodegeneration in a novel spinocerebellar ataxia type 13 mouse model

  Junxiang Yin, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Cleaved Caspase 3 (CC3, Cell signaling, #9664, 1:1000) at 4°C overnight ...
• The temporal refinement of Dach1 is a key step in the functional maturation of primary somatosensory neurons

  Tünde Szemes, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-cleaved Caspase-3 (1:1000, Cell Signaling, #9661), rabbit anti-Mef2c (1:400 ...
• Deep learning-based image classification reveals heterogeneous execution of cell death fates during viral infection

  Edoardo Centofanti, et al., bioRxiv - Systems Biology 2024

  Quote: ... rabbit anti-Cleaved Caspase 3 (clone 9661, Cell Signaling Technologies), Rabbit anti-Cleaved Caspase 8 (clone D5B2 ...
• Mapping herpesvirus-driven impacts on the cellular milieu and transcriptional profile of Kaposi sarcoma in patient-derived mouse models

  Xiaofan Li, et al., bioRxiv - Microbiology 2024

  Quote: ... rabbit anti-VEGF Receptor 3 (cat# 2638; Cell Signaling Technology), rabbit anti-FAP (cat# 66562 ...
• TFAP2C and HNRNPK control mTOR cell metabolism and prion propagation

  Stefano Sellitto, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Cleaved Caspase 3 1:1000 (Cell Signaling Technology, 9661S), anti-Caspase 3 1:1000 (Novus Biologicals ...
• The pro-apoptotic effect of chronic contractile activity-induced extracellular vesicles on Lewis Lung Carcinoma cells

  Patience O. Obi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti-cleaved caspase-3 (9661, Cell Signaling, 1:1000), rabbit anti-Bcl-2 (3498 ...
• Disruption of mitochondrial folate metabolism leads to mitochondrial DNA leakage and activation of apoptotic or inflammatory pathways

  Sinwoo Hwang, Cameron Baker, Martha S. Field, bioRxiv - Biochemistry 2024

  Quote: ... Caspase-3 (1:1000, 9662, Cell Signaling, Danvers, MA, USA), Cleaved caspase-3 (1:1000 ...
• Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy

  Meghan Logun, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit polyclonal anti-cleaved caspase 3 (Cell Signaling Technology, 9661S), rabbit monoclonal anti-Ki67 (Abcam ...
• Tritrichomonas muris sensitizes the intestinal epithelium to doxorubicin-induced apoptosis

  Nicolas V. Janto, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:400 anti-Cleaved caspase 3 (CC3; Cell Signaling; 9661S), 1:200 anti-OLFM4 (Cell Signaling ...
• The GluA1 cytoplasmic tail regulates intracellular AMPA receptor trafficking and synaptic transmission onto dentate gyrus GABAergic interneurons, gating response to novelty

  Gerardo Leana-Sandoval, et al., bioRxiv - Neuroscience 2024

  Quote: ... After blocking with 5% swine serum (Jackson Immuno Research, #014-000-121) and 2% BSA (Cell Signaling, #9998S) in permeabilizing conditions (0.1% Triton X-100 ...
• XPO1 inhibition modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis

  Andrew E. Evans, et al., bioRxiv - Cancer Biology 2024

  Quote: ... The slides were then washed with PBS and blocked for 2 hours using TBST + 5% NGS (Cell Signaling). Slides were then exposed to anti-XPO1 (1/200 ...
• TRIM5α restriction of HIV-1-N74D viruses in lymphocytes is caused by a loss of cyclophilin A protection

  Anastasia Selyutina, et al., bioRxiv - Microbiology 2020

  Quote: ... and activated with IL-2 (100 U/ml) (Human IL-2; Cell Signaling Technology, #8907SF) and phytohemagglutinin (1 µg/ml ...
• Preserving endothelial integrity in human saphenous veins during preparation for coronary bypass surgery

  Meghan W. Sedovy, et al., bioRxiv - Physiology 2023

  Quote: ... and nuclear factor erythroid 2-related factor 2 (NRF2, #12721, 1:25, Cell Signaling Technology). Antibody binding was identified by incubation with goat anti-rabbit or anti-mouse secondary antibodies (Thermo Fisher Scientific ...
• Calcium-Mediated Modulation of Blood-Brain Barrier Permeability by Laser Stimulation of Endothelial-Targeted Nanoparticles

  Xiaoqing Li, et al., bioRxiv - Bioengineering 2022

  Quote: ... P-p44/42 ERK1/2 and p44/42 ERK1/2 were purchased from Cell Signaling Technology. Gold (III ...
• Radiation-Induced Changes in Energy Metabolism Result in Mitochondrial Dysfunction in Salivary Glands

  Lauren G. Buss, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and anti-extracellular signal-regulated protein kinases 1/2 (ERK1/2) (p44/42 MAPK, Cell Signaling). For detection ...
• Development of an automated high-content immuno-fluorescence assay of pSmads quantification: proof-of-concept with drugs inhibiting the BMP/TGFβ pathways

  Valia Khodr, et al., bioRxiv - Bioengineering 2023

  Quote: ... anti-pSmad 1/5/9 (ref: 13820S) and anti-pSmad 2 (ref: 18338S) antibodies were obtained from Cell signaling. The secondary antibody conjugated to Alexa555 or Alexa488 were purchased from Invitrogen ...
• The VGCC auxiliary subunit α2δ1 is an extracellular GluA1 interactor and regulates LTP, spatial memory, and seizure susceptibility

  Gerardo Leana-Sandoval, et al., bioRxiv - Neuroscience 2024

  Quote: ... After blocking tissue with 5% swine serum (Jackson Immuno Research, # 014-000-121) and 2% BSA (Cell Signaling, #9998S) in permeabilizing conditions (0.1% Triton X-100 ...
• Conditional ERK3 overexpression cooperates with PTEN deletion to promote lung adenocarcinoma formation in mice

  Sreeram Vallabhaneni, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-ERK1/2 (Cell signaling, CST4695), anti-phospho-ERK1/2 (Cell Signaling ...
• Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

  Jill E. Hunter, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK 1/2 (9102 Cell Signaling), AKT (phospho S473 ...
• BRD4-mediated repression of p53 is a target for combination therapy in AML

  Anne-Louise Latif, et al., bioRxiv - Cell Biology 2020

  Quote: ... BCL-2 (Cell signaling, 2870, RRID:AB_2290370) (Supplementary Table 6) ...
• Gain-of-function mutation in Gli3 causes ventricular septal defects

  Antonia Wiegering, et al., bioRxiv - Developmental Biology 2020

  Quote: ... pMEK1/2 (#9121; Cell Signaling Technology), acetylated α-tubulin (#sc-23950 ...
• PD-1-induced T cell exhaustion is controlled by a Drp1-dependent mechanism

  Luca Simula, et al., bioRxiv - Immunology 2021

  Quote: ... anti-ERK1/2 (Cell Signaling 4695), anti-Hsp90 (Cell Signaling 4877) ...
• Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

  Brian Czaya, et al., bioRxiv - Cell Biology 2021

  Quote: ... Phospho- ERK1/2 (9101, Cell Signaling), phospho-STAT3 (9145 ...
• Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells via modulating metabolism and death pathways

  J Vial, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-ERK1/2 (9102, Cell signaling), anti-mTOR (2983 ...
• Chronic high dietary sucrose induces sexually dimorphic metabolic adaptations in liver and adipose tissue

  Erin J Stephenson, et al., bioRxiv - Physiology 2020

  Quote: ... ACC1/2 (#3676S, Cell Signaling Technology), phospho-ACC1/2 Ser79 (#3661 ...
• Pseudomonas aeruginosa Stimulates Inflammation and Enhances KSHV-Induced Cell Proliferation and Cellular Transformation through Both LPS and Flagellin

  Ashley Markazi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... ERK1/2 (4695S, Cell Signaling Technology), phospho-ERK1/2 (4370S ...
• The Mechanism of Neurite Outgrowth Induction by Novel Synthetic Retinobenzoic Acids

  Yang Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... phospho-ERK1/2 (Cell Signaling Technology), or phospho-mTOR (Cell Signaling Technology ...
• IKK2/NFkB signaling controls lung resident CD8 T cell memory during influenza infection

  Curtis J. Pritzl, et al., bioRxiv - Immunology 2022

  Quote: ... phosphorylated ERK1/2 from Cell Signaling; anti-SMAD7(293739 ...
• Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFкB p50 recruitment, and H3K9me2 deposition

  Veronica Elizabeth Burns, Tom Klaus Kerppola, bioRxiv - Immunology 2022

  Quote: ... αlaminB1 (Cell Signaling 13435, lot 2), normal rabbit IgG (Santa Cruz sc-2027 ...
• Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFкB p50 recruitment, and H3K9me2 deposition

  Veronica Elizabeth Burns, Tom Klaus Kerppola, bioRxiv - Immunology 2022

  Quote: ... αG9a (Cell Signaling 3306, lot 2), αGLP (Abcam ab41969 ...
• TCF-7 is dispensable for anti-tumor response but required for persistent function of mature CD8 T cells

  Rebecca Harris, et al., bioRxiv - Immunology 2022

  Quote: ... JAK 2(Cell Signaling Technology # 3230), JAK3 (Cell Signaling Technology #8863) ...
• TCF-7 is dispensable for anti-tumor response but required for persistent function of mature CD8 T cells

  Rebecca Harris, et al., bioRxiv - Immunology 2022

  Quote: ... ERK1-2 (Cell Signaling Technology #9107), JAK 2(Cell Signaling Technology # 3230) ...
• YTHDF1 drives intestinal immune response against bacterial infection

  Xin Zong, et al., bioRxiv - Immunology 2020

  Quote: ... ERK1/2 (Cell Signaling Technology, 9102), phospho-ERK1/2 (HuaAn ...
• AMPK-dependent phosphorylation is required for transcriptional activation of TFEB/TFE3

  Mathieu Paquette, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ACC1/2 (Cell Signaling Technology, 3676), p-ACC1/2 (S79 ...
• 17α-estradiol, a lifespan-extending compound, attenuates liver fibrosis by modulating collagen turnover rates in male mice

  Samim Ali Mondal, et al., bioRxiv - Physiology 2022

  Quote: ... MMP-2 (Cell Signaling; 1:1000), TIMP-1 (Sino Biological ...