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5051 - 5100 of 10000+ citations for 6 4 METHOXY PHENYL 3 METHYL IMIDAZO 2 1 B THIAZOLE 5 CARBALDEHYDE since 2019

• The mitochondrial deubiquitinase USP30 regulates AKT/mTOR signaling

  Ruohan Zhang, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... P70S6K (Cell Signaling Technology, 9202S, 1:1000); LC3A/B (Cell Signaling Technology ...
• The mitochondrial deubiquitinase USP30 regulates AKT/mTOR signaling

  Ruohan Zhang, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... NDP52 (Cell Signaling Technology, 60732S, 1:1000); p-P70S6K (Cell Signaling Technology ...
• Brain endothelial cell tissue-nonspecific alkaline phosphatase (TNAP) activity promotes maintenance of barrier integrity via the ROCK pathway

  Divine C. Nwafor, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Vimentin (Cell Signaling Technologies (1:500), AB_10695459 ...
• mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination

  Gustavo Della-Flora Nunes, et al., bioRxiv - Neuroscience 2020

  Quote: ... p-S6 1:500 (Cell signaling #4858), S6 1:500 (Cell signaling #2217) ...
• mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination

  Gustavo Della-Flora Nunes, et al., bioRxiv - Neuroscience 2020

  Quote: ... 4E-BP1 1:500 (Cell signaling #9644), p-S6 1:500 (Cell signaling #4858) ...
• Common fragile sites are characterised by faulty condensin loading after replication stress

  Lora Boteva, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and GAPDH (Cell Signaling 2118L, 1:5000).
• The mitochondrial deubiquitinase USP30 regulates AKT/mTOR signaling

  Ruohan Zhang, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... Parkin (Cell Signaling Technology, 4211S, 1:1000); AKT (Cell Signaling Technology ...
• The mitochondrial deubiquitinase USP30 regulates AKT/mTOR signaling

  Ruohan Zhang, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... mTOR (Cell Signaling Technology, 2983S, 1:1000); TOM20 (Cell Signaling Technology ...
• The mitochondrial deubiquitinase USP30 regulates AKT/mTOR signaling

  Ruohan Zhang, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... AKT (Cell Signaling Technology, 4685S, 1:1000); Cleaved PARP (Cell Signaling Technology ...
• The mitochondrial deubiquitinase USP30 regulates AKT/mTOR signaling

  Ruohan Zhang, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... TOM20 (Cell Signaling Technology, 42406S, 1:1000); NDP52 (Cell Signaling Technology ...
• Impaired p53-mediated DNA damage response contributes to microcephaly in Nijmegen Breakage Syndrome patient-derived cerebral organoids

  Soraia Martins, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-H2AX (1:1000, Cell Signaling), mouse anti β-actin (1:4000 ...
• The transcription factor CLAMP is required for neurogenesis in Drosophila melanogaster

  Maria A. Tsiarli, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-DCP1 (1:100, Cell Signaling), rat anti-Deadpan (Dpn ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Myc-Tag (1:1,000; Cell Signaling Technology), rabbit V5-Tag (1:1,000 ...
• Precise control of microtubule disassembly in living cells

  Grace Y. Liu, et al., bioRxiv - Cell Biology 2021

  Quote: ... and GAPDH (1:5000; Cell Signaling, 2118), which were diluted with blocking buffer ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit H3K27me3 (1:1,000; Cell Signaling Technology), mouse H3K27me3 (1:250 ...
• Depletion of nuclear pore protein NUP210 suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

  Ruhul Amin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and SUZ12 (1:1,000; Cell Signaling Technology). Anti-mouse secondary antibody (GE Healthcare ...
• ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells

  Priyanka Verma, et al., bioRxiv - Cancer Biology 2020

  Quote: ... GAPDH (Cell Signaling 2118S, 1:2000 dilution), mouse Anti-FLAG (F1804 ...
• Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis

  Katsuhiro Togami, et al., bioRxiv - Cancer Biology 2020

  Quote: ... TRAIL (Cell Signaling technology, #3219, 1:1000), β-actin (Sigma-Aldrich ...
• Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis

  Katsuhiro Togami, et al., bioRxiv - Cancer Biology 2020

  Quote: ... IRF7 (Cell Signaling technology, #4920, 1:1000), TRAIL (Cell Signaling technology ...
• PDGFR dimer-specific activation, trafficking and downstream signaling dynamics

  Madison A. Rogers, Katherine A. Fantauzzo, bioRxiv - Cell Biology 2021

  Quote: ... Rab5 (1:200; C8B1; 3547; Cell Signaling); Rab7 (1:100 ...
• PDGFR dimer-specific activation, trafficking and downstream signaling dynamics

  Madison A. Rogers, Katherine A. Fantauzzo, bioRxiv - Cell Biology 2021

  Quote: ... Rab7 (1:100; D95F2; 9367; Cell Signaling); Rab4 (1:200 ...
• PDGFR dimer-specific activation, trafficking and downstream signaling dynamics

  Madison A. Rogers, Katherine A. Fantauzzo, bioRxiv - Cell Biology 2021

  Quote: ... Akt (1:1000; 9272; Cell Signaling Technology); horseradish peroxidase-conjugated goat anti-rabbit IgG (1:20,000 ...
• PDGFR dimer-specific activation, trafficking and downstream signaling dynamics

  Madison A. Rogers, Katherine A. Fantauzzo, bioRxiv - Cell Biology 2021

  Quote: ... Rab11 (1:100; D4F5; 5589; Cell Signaling).
• Marked Synergy by Vertical Inhibition of EGFR signaling in NSCLC Spheroids: SOS1 as a therapeutic target in EGFR-mutated cancer

  Patricia L. Theard, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-AKT (Cell Signaling 2920; 1:1000), anti-HSP90 (Santa Crux sc-7947 ...
• Marked Synergy by Vertical Inhibition of EGFR signaling in NSCLC Spheroids: SOS1 as a therapeutic target in EGFR-mutated cancer

  Patricia L. Theard, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-pEGFR (Cell Signaling 11862; 1:1000), anti-pERK1/2 (Cell Signaling 4370 ...
• SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability

  Alison D. Parisian, et al., bioRxiv - Cancer Biology 2020

  Quote: ... HDAC1 (rabbit, 1:1000, Cell Signaling, 2062), SMARCD1 (mouse ...
• Tumor Necrosis Factor Receptor Signaling Modulates Carcinogenesis in a Mouse Model of Breast Cancer

  Ling He, et al., bioRxiv - Cancer Biology 2020

  Quote: ... cMyc (Cell Signaling, Cat # 5605S, 1:1000), or GAPDH (Abcam ...
• Tumor Necrosis Factor Receptor Signaling Modulates Carcinogenesis in a Mouse Model of Breast Cancer

  Ling He, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Vimentin (Cell Signaling, Cat #5741S, 1:200), Snail (Abcam ...
• Tumor Necrosis Factor Receptor Signaling Modulates Carcinogenesis in a Mouse Model of Breast Cancer

  Ling He, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Klf4 (Cell Signaling, Cat # 4038S, 1:1000), cMyc (Cell Signaling ...
• Tumor Necrosis Factor Receptor Signaling Modulates Carcinogenesis in a Mouse Model of Breast Cancer

  Ling He, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Oct4 (Cell Signaling, Cat # 2750S, 1:1000), Klf4 (Cell Signaling ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... mTOR 1:1000 (7C10, Cell Signaling, 2983), phospho-p70S6K1 1:1000 (Cell Signaling ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Rheb 1:1000 (E1G1R, Cell Signaling, 13879), TSC2 1:1000 (D93F12 ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... LC3B 1:1000 (D11, Cell Signaling, 3868), HSP90 1:1000 (Cell Signaling ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... phospho-p70S6K1 1:1000 (Cell Signaling, 9205), p70S6K1 1:1000 (Cell Signaling ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... TSC2 1:1000 (D93F12, Cell Signaling, 4308), Akt 1:1000 (Cell Signaling ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... GAPDH 1:10,000 (14C10, Cell Signaling, 2118), TFAM 1:2000 (Abcam ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... mTOR 1:500 (7C10, Cell Signaling, 2983), GAPDH 1:1000 (14C10 ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... GAPDH 1:1000 (14C10, Cell Signaling, 2118). ImageJ software (NIH ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... pAKT (Cell Signaling Technology, # 3787S, 1:50), SYP (BD Biosciences ...
• Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells

  Chieh-Yang Cheng, et al., bioRxiv - Cancer Biology 2019

  Quote: ... PTEN (Cell Signaling Technology, #9559S, 1:800), pAKT (Cell Signaling Technology ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... total Chk2 (Cell Signaling #2662, 1:1000), phospho-Chk2 (Thr68 ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... phospho-Rb (Cell Signaling #8516, 1:1600), p53 (Santa Cruz #sc-126 ...
• Nutrient metabolism regulates insulin granule formation in the pancreatic islet β-cell via ER redox homeostasis

  Kristen E. Rohli, et al., bioRxiv - Cell Biology 2021

  Quote: ... CHOP (mouse, 1:1000 Cell Signaling 2895), cleaved Caspase 3 (rabbit ...
• Nucleotide imbalance decouples cell growth from cell proliferation

  Frances F. Diehl, et al., bioRxiv - Cell Biology 2021

  Quote: ... and vinculin (Cell Signaling Technology, 1:1,000). The following day ...
• AMPK promotes Arf6 activation in a kinase-independent manner upon energy deprivation

  Kuan-Jung Chen, Jia-Wei Hsu, Fang-Jen S. Lee, bioRxiv - Cell Biology 2021

  Quote: ... anti-AMPKα2 (1:1,000, 2757S; Cell Signaling), anti-CYTH2/ARNO (1:1,000 ...
• AMPK promotes Arf6 activation in a kinase-independent manner upon energy deprivation

  Kuan-Jung Chen, Jia-Wei Hsu, Fang-Jen S. Lee, bioRxiv - Cell Biology 2021

  Quote: ... anti-AMPKα1 (1:1,000, 2795S; Cell Signaling), anti-AMPKα2 (1:1,000 ...
• Polo-like kinase 4 homodimerization is not required for catalytic activation, autodestruction, or centriole assembly

  John M. Ryniawec, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-myc (1:3000, Cell Signaling), mouse anti-GFP monoclonal JL8 (1:3000 ...
• Dietary Amino Acids Impact LRRK2-induced Neurodegeneration in Parkinson’s Disease Models

  Vinita G. Chittoor-Vinod, et al., bioRxiv - Neuroscience 2020

  Quote: ... LRRK2 (1:1000; Cell Signaling Technology, 13046); Rps15 (1:500 ...
• Dietary Amino Acids Impact LRRK2-induced Neurodegeneration in Parkinson’s Disease Models

  Vinita G. Chittoor-Vinod, et al., bioRxiv - Neuroscience 2020

  Quote: ... Actin (1:1000, Cell Signaling Technology, 4967); p-LRRK2 (1:750 ...
• Gene replacement therapy provides benefit in an adult mouse model of Leigh syndrome

  Robin Reynaud Dulaurier, et al., bioRxiv - Neuroscience 2020

  Quote: ... NeuN (rabbit, 1:1000, Cell Signaling, #12943), TH (mouse ...