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4951 - 5000 of 10000+ citations for 4' Trifluoromethoxy 5 trifluoromethyl 1 1' biphenyl 3 carboxylic acid since 2020

• A missense in HSF2BP causing Primary Ovarian Insufficiency affects meiotic recombination by its novel interactor C19ORF57/MIDAP

  Natalia Felipe-Medina, et al., bioRxiv - Genetics 2020

  Quote: ... rat αRPA2 (1:1000, Cell Signaling (Cat 2208S)) ...
• Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

  Allison K. Meyers, et al., bioRxiv - Immunology 2021

  Quote: ... p-ACC (Cell Signaling, no. 3661s; 1:750), TUFM (Novus Biologicals ...
• A critical role for E2-p53 interaction during the HPV16 life cycle

  Christian T. Fontan, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1:1000 (Ser345) (Cell Signaling; cat. No. 2341S), phosphor CHK2 (Thr68) ...
• AAV-delivery of diacylglycerol kinase kappa achieves long-term rescue of Fmr1-KO mouse model deficits of fragile X syndrome

  Karima Habbas, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-S6 (5G10, 1:1000 #2217S, Cell Signaling), anti-p-S6 (Ser235/236 ...
• AAV-delivery of diacylglycerol kinase kappa achieves long-term rescue of Fmr1-KO mouse model deficits of fragile X syndrome

  Karima Habbas, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-EIF4 (1:1000 BSA, #9742, Cell Signaling), anti-puromycin (12D10 ...
• 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

  Hideaki Tomita, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-phospho-MEK (1:1000; Cell Signaling), rabbit anti-phospho-cebpβ (1:1000 ...
• Sortilin exhibits tumor suppressor-like activity by limiting EGFR transducing function

  E. Lapeyronnie, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ERK1/2 (#9102, 1:1000 dilution, Cell Signaling), pAKT (Ser 473 ...
• Cooperation between oncogenic Ras and p53 stimulates JAK/STAT non-cell autonomously to promote Ras tumor radioresistance

  Yong-Li Dong, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or anti-STAT (1:1000, Cell Signaling #30835) or anti-GAPDH (1:1000 ...
• Cooperation between oncogenic Ras and p53 stimulates JAK/STAT non-cell autonomously to promote Ras tumor radioresistance

  Yong-Li Dong, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or anti-GAPDH (1:1000, Cell signaling #5174S). Secondary horseradish peroxidase (HRP ...
• Glycocalyx-Mediated Vascular Dissemination of Circulating Tumor Cells

  Giovanni S. Offeddu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Imaging of ICAM-1 (62133S, Cell Signaling Technologies), ZO-1 (33-9100 ...
• Phosphorylation of pyruvate dehydrogenase marks the inhibition of in vivo neuronal activity

  Dong Yang, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-Orexin (1:100, Cell Signaling #16743), rabbit anti-MCH (1:200 ...
• Targeting the Cx26/NANOG/Focal Adhesion Kinase Complex via Cell-Penetrating Peptides in Triple-Negative Breast Cancers

  Erin E. Mulkearns-Hubert, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-FAK (D2R2E) (Cell Signaling #13009; 1:1000), anti-Lamin A/C (Proteintech #10298-1-AP ...
• Impaired migration and premature differentiation underlie the neurological phenotype associated with PCDH12 loss of function

  Jennifer Rakotomamonjy, et al., bioRxiv - Neuroscience 2023

  Quote: ... alpha-Tubulin (1:1000, Cell Signaling Technology, 2144), N-cadherin (1:1000 ...
• Impaired migration and premature differentiation underlie the neurological phenotype associated with PCDH12 loss of function

  Jennifer Rakotomamonjy, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1:100 phospho-Vimentin (Cell Signaling Technology, 3877S), 1:500 phospho-Histone H3 (Abcam ...
• Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival

  Conor T. Ronayne, et al., bioRxiv - Cell Biology 2023

  Quote: ... p-eif2α (S51, Cell Signaling, 119A11, 1:1000), eif2α (total ...
• Prostaglandin E₂ controls the metabolic adaptation of T cells to the intestinal microenvironment

  Matteo Villa, et al., bioRxiv - Immunology 2023

  Quote: ... anti-ATG5 (clone D5F5U, 1:1,000, Cell Signaling), anti-Gclc (clone OTI1A3 ...
• Cell migration CRISPRi screens in human neutrophils reveal regulators of context-dependent migration and differentiation state

  Nathan M. Belliveau, et al., bioRxiv - Cell Biology 2022

  Quote: ... p-Ser473 Akt (1:2000; Cell Signaling, #4060), total mTOR (1:1000 ...
• Tumour Extracellular Vesicles Induce Neutrophil Extracellular Traps To Promote Lymph Node Metastasis

  Xin Su, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-Rab27a (1:500, 69295; Cell Signaling).
• An Innovative Non-Hormonal Strategy Targeting Redox Active Metals to Down-Regulate Estrogen-, Progesterone-, Androgen- and Prolactin-Receptors in Breast Cancer

  Faten Shehadeh-Tout, et al., bioRxiv - Cancer Biology 2023

  Quote: ... AR (1:300; Cat #: 5153; Cell Signaling Technology), and PR (1:700 ...
• Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A

  Stefan Harjes, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-HA (#3724S, 1:2500, Cell Signaling), and rabbit anti-Cas9 (#ab189380 ...
• Insulin-mediated endothelin signaling is antiviral during West Nile virus infection

  Chasity E. Trammell, et al., bioRxiv - Microbiology 2023

  Quote: ... anti-Akt (pan) (1:2,000) (Cell Signaling 4691), or anti-actin (1:10,000 ...
• PD1 is transcriptionally regulated by LEF1 in mature T cells

  Pin Zhao, Lanming Sun, Cong Zhao, Samiullah Malik, bioRxiv - Immunology 2023

  Quote: ... LEF1 (Dilution of 1:5000, C12A5, Cell Signaling); β-actin (Dilution of 1:2000 ...
• Oropouche virus glycoprotein topology and cellular requirements for virus assembly

  Natalia S. Barbosa, et al., bioRxiv - Microbiology 2022

  Quote: ... anti-HA (Cell Signaling Technology C29F4, 1:20,000), anti-actin (Sigma A3853 ...
• RHINO restricts MMEJ activity to mitosis

  Alessandra Brambati, et al., bioRxiv - Molecular Biology 2023

  Quote: ... HUS1 (D4J9H, Cell Signaling Technology; 1: 1000 dilution), Polθ (gift from Repare therapeutics ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... phospho-AKT S473 (Cell Signaling, #4060, 1:1000), c-Raf (Cell Signaling ...
• Repurposing of the antibiotic nitroxoline for the treatment of mpox

  Denisa Bojkova, et al., bioRxiv - Microbiology 2022

  Quote: ... phospho-AKT T308 (Cell Signaling, #2965, 1:1000), phospho-AKT S473 (Cell Signaling ...
• Early mitochondrial dysfunction proceeds neuroinflammation, synaptic alteration, and autophagy impairment in hippocampus of App knock-in Alzheimer mouse models

  Luana Naia, et al., bioRxiv - Neuroscience 2023

  Quote: ... ULK1 (1:500) (Cell signaling, Cat. no. 8054), pSer555-ULK1 (1:500 ...
• The host-directed therapeutic imatinib mesylate accelerates immune responses to Mycobacterium marinum infection and limits pathology associated with granulomas

  Tesia L. Cleverley, et al., bioRxiv - Immunology 2022

  Quote: ... and GAPDH (D16H11) antibody (1:1000, Cell Signaling) were used sequentially on the same membrane to quantify and normalize protein content.
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-GAPDH (1:5,000, #2188, Cell signaling technology), anti-HA (1:1,000 ...
• Skeletal Muscle Proteostasis Promotes Central Nervous System Function and Reduces Neuroinflammation during Aging and Neurodegenerative Disease

  Ian Matthews, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-LC3 antibody (Cell Signaling, 2775S, 1:1000) or anti-GAPDH (Invitrogen ...
• Innate immune receptor C5aR1 regulates cancer cell fate and can be targeted to improve radiotherapy in tumours with immunosuppressive microenvironments

  Callum Beach, et al., bioRxiv - Cancer Biology 2023

  Quote: ... RelA/p65 (Cell Signaling #3034, concentration 1:1000), pRelA/p65-S536 (Cell Signaling #3033T ...
• Drosophila FMRP recruits the miRISC to target mRNAs to repress translation

  Navneeta Kaul, et al., bioRxiv - Molecular Biology 2023

  Quote: ... HA (dilution 1:500; Cell Signaling Technology #2367), FLAG (dilution 1:1000 ...
• Sonic Hedgehog Activates Prostaglandin Signaling to Stabilize Primary Cilium Length

  Shariq S. Ansari, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-acetylated α-tubulin (Cell Signaling, 1:1000), anti-ARL13B (Antibodies Incorporated ...
• Aged Breast Matrix Bound Vesicles Promote Breast Cancer Invasiveness

  Jun Yang, et al., bioRxiv - Bioengineering 2023

  Quote: ... or Adiponectin antibody (Cell Signaling Technology,1:200) for 48 hours ...
• OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence

  Mariarosaria De Rosa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... pCHK2 T68 (Cell Signaling 2197; 1:1000 WB), pCHK1 S345 (Cell Signaling 2348 ...
• OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence

  Mariarosaria De Rosa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... pCHK1 S345 (Cell Signaling 2348; 1:500 WB), pATM S 1981 (Abcam ab81292 ...
• Melatonin alleviates LPS-induced abnormal pregnancy through MTNR1B regulation of m6A

  Shisu Zhao, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-MTNR1B (1:100, Cell Signaling Technology, USA). Then ...
• Noncanonical Rab9a action supports endosomal exit of human papillomavirus during virus entry

  Jeongjoon Choi, Daniel DiMaio, bioRxiv - Microbiology 2023

  Quote: ... pan actin (Cell Signaling Technology, 4968, 1:2,000), FLAG (Sigma ...
• NF-κB c-REL-OTUD4 axis regulates B-cell receptor in B-cell lymphoma

  Eslam Katab, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD79B (1:1000, rabbit, Cell Signaling Technology #96024), FLAG (1:1,000 ...
• VRK3 depletion induces cell cycle arrest and metabolic reprogramming of Pontine Diffuse Midline Glioma (DMG)-K27 altered cells

  Virginie Menez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and anti-Phalloidine (1/200 #8940S, Cell signaling) and 45 minutes with secondary antibodies (Alexa fluor ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Amyloid-β (1:100; Cell Signaling, 8243), anti-Amyloid-β (1-42 ...
• Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4

  Evangelia Chavdoula, et al., bioRxiv - Cancer Biology 2023

  Quote: ... H3K4me3 1:50 (Cell Signaling Technology, Cat 9751), H3K27me3 1:50 (Cell Signaling Technology ...
• VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

  Ann Schirin Mirsanaye, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Ubiquitin (43124S, Cell Signaling Technology, rabbit, 1:1000); Ubiquitin (sc-8017 ...
• Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes

  Anastasia Knyazeva, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Rubicon (1:1000, #8465, Cell Signaling Technology), anti-EGFR (1:100 ...
• Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes

  Anastasia Knyazeva, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-ATG9A (1:1000, #13509, Cell Signaling Technology), anti-Rubicon (1:1000 ...
• Th17 cells target the metabolic miR-142-5p-SDHC/SDHD axis promoting invasiveness and progression of cervical cancers

  Maike Pohlers, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-vimentin (1:1000; AB_10695459; Cell Signaling) and mouse anti-β-Actin antibody (1:5000 ...
• A GPCR screening in human keratinocytes identifies that the metabolite receptor HCAR3 controls epithelial proliferation, migration, and cellular respiration

  M. Pilar Pedro, et al., bioRxiv - Cell Biology 2023

  Quote: ... ERK (Cell Signaling; catalog no. 4695; 1:1000), pAKT(Thr308 ...
• The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC reprogramming

  Mercedes Barrero, et al., bioRxiv - Genetics 2023

  Quote: ... rabbit anti IRF1 1:1000 (Cell signaling, 8478S), mouse anti α-Tubulin 1:10000 (Sigma Aldrich ...
• Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in Atypical Teratoid/Rhabdoid Tumors

  Dennis S. Metselaar, et al., bioRxiv - Cancer Biology 2023

  Quote: ... NF-kB (1:500, #D14E12, Cell Signaling technology), Sirtuin 1 (SIRT1 ...
• R-loop landscapes in the developing human brain are linked to neural differentiation and cell-type specific transcription

  Elizabeth A. LaMarca, et al., bioRxiv - Genomics 2023

  Quote: ... Sox2 (Cell Signaling, cat. no. #2748, 1:500), MAP2AB (Sigma ...