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451 - 500 of 2359 citations for 2 Trimethylsilyl Furo 3 2 B Pyridine 6 Carbaldehyde since 2020

• Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations

  Maria Victoria Hinckelmann, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-myosin light chain 2 (Cell signaling, 1:100), mouse anti-phospho myosin light chain 2 (Cell signaling ...
• Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular cells

  Yihong Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... p42/44 MAPK (ERK1/2, Cell Signaling Technology, Danvers, MA), phosphor-p42/44 MAPK (p-ERK1/2 ...
• SCF^FBXW11 complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation

  Ben Jin, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-ERK1/2 (Cell Signaling Technology, #4695, 1:1,000 dilution), anti-p-p38 MAPK (Santa Cruz Biotechnology ...
• Neural stem cells protect blood-brain barrier integrity via the p38, JNK, and ERK1/2 pathways following intracerebral hemorrhage in rats

  Jing Sun, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-p-ERK1/2 (Cell Signaling, USA, 1:500 dilution), anti-p-p38 (Cell Signaling ...
• LRRK2 regulates synaptic function through BDNF signaling and actin cytoskeleton

  Giulia Tombesi, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit α-ERK1/2 (4695, Cell Signaling Technology, 1:1000); mouse α-GAPDH (CSB-MA000195 ...
• Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulations

  Maria Victoria Hinckelmann, et al., bioRxiv - Developmental Biology 2023

  Quote: ... rabbit anti-myosin light chain 2 (Cell signaling, 1:1000), rabbit anti-phospho myosin light chain 2 (Cell signaling ...
• Ellagic acid ameliorates atherosclerosis by targeting the epidermal growth factor receptor

  Ye-Wei Huang, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-phospho-ERK1/2 (4370S, Cell Signaling Technology, MA, USA), and anti-β-actin (66009-1-IG ...
• Continuous exposure to 60 Hz extremely low frequency electromagnetic field at 10 to 16 mT promotes various human cell proliferation by activating extracellular-signal-regulated kinase

  Jaeseong Goh, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-ERK1/2 (Cell Signaling Technology, Inc., MA, USA, #9102), anti-phospho-Akt (Cell Signaling Technology ...
• Altered liver metabolism post-wean abolishes efficacy of vitamin D for breast cancer prevention in a mouse model

  Sarah M Bernhardt, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Cycle 2 F4/80 (Cell Signaling, 70076S, 1:500, 1hr), Cycle 3 CD45 (BD Pharmingen ...
• The Src-family kinase Lyn plays a critical role in establishing and maintaining B cell anergy by suppressing PI3K-dependent signaling

  Brigita E. Fiske, et al., bioRxiv - Immunology 2024

  Quote: ... p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling Technology), pan Erk (BD) ...
• Reorganization of innate immune cell lipid profiles by bioinspired meroterpenoids to limit inflammation

  Lorenz Waltl, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... rabbit anti-phospho-MEK1/2 (1:1000; #9121; Cell Signaling), goat anti-FLAP (1:1000 ...
• A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy

  Bingxue Qi, et al., bioRxiv - Physiology 2024

  Quote: ... p44/42 MAPK (Erk1/2) (#4695, Cell signaling, 1:1000), ROCK2 (#8236 ...
• A negative feedback loop between small GTPase Rap1 and mammalian tumor suppressor homolog KrsB regulates cell-substrate adhesion in Dictyostelium

  Yulia Artemenko, et al., bioRxiv - Cell Biology 2024

  Quote: ... The following primary antibodies were used: phosphoMst1/2 (Cell Signaling), phospho-PKCζ Thr410 (Cell Signaling) ...
• Glutamate Transport Proteins and Metabolic Enzymes are Poor Prognostic Factors in Invasive Lobular Carcinoma

  Todd A. Young, et al., bioRxiv - Cancer Biology 2024

  Quote: ... GLUD1/2 (1:1000, Cell Signaling Technology Cat# 12793, RRID:AB_2750880); GPX4 (1:1000 ...
• Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience

  Carron Charline, et al., bioRxiv - Neuroscience 2024

  Quote: ... rabbit anti-p-ERK1/2 (1:500, Cell Signaling 9101S), rabbit anti-RFP (1:500 ...
• Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells

  Kaitlin P. McCreery, et al., bioRxiv - Cell Biology 2024

  Quote: ... p44/42 MAPK Erk1/2 (Cell Signaling 4695, 1:1000), RNApol2 PS2 (Abcam ab5095 ...
• Addition of a carboxy terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice

  Chirine Toufaily, et al., bioRxiv - Physiology 2021

  Quote: ... Phospho-p44/42 MAPK (Thr202/Tyr204 pERK1/2; 9101S) and p44/42 MAPK (ERK1/2; 9102S) antibodies were from Cell Signaling Technologies (Danvers, MA, USA). HRP-conjugated goat anti-rabbit (170–6516 ...
• Retinoid acid receptor β mechanically regulates the activity of pancreatic cancer cells

  Carlos Matellan, et al., bioRxiv - Bioengineering 2022

  Quote: ... Cells on coverslips were incubated with diluted primary antibodies in PBST against myosin light chain-2 (MLC-2, Cell Signaling Technology, 3672S, Rabbit, 1:100), RAR-β (Abcam ...
• The WD and linker domains of ATG16L1 required for non-canonical autophagy limit lethal respiratory infection by influenza A virus at epithelial surfaces

  Yingxue Wang, et al., bioRxiv - Microbiology 2020

  Quote: ... LC3A/B (Cell signaling 41085) and actin (Sigma ...
• Autophagy limits inflammatory gene expression through targeting of nuclear p65/RelA by LC3 and p62 for lysosomal degradation

  Cristina Brischetto, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 40nM Leptomycin B (Cell signaling. Ionizing irradiation (20 or 80 Gy ...
• Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for co-receptor discrimination

  Naotaka Tsutsumi, et al., bioRxiv - Biophysics 2022

  Quote: ... Wnt 5a/b (Cell signaling) and HSP90 (Cell Signaling).
• Top-down design of protein nanomaterials with reinforcement learning

  Isaac D. Lutz, et al., bioRxiv - Synthetic Biology 2022

  Quote: ... b-Actin (Cell Signaling, 3700S) at 1:10,000 ...
• Wee1 inhibition decouples Cdk1 and Plk1 activities: a role for gradual Cdk1 activation throughout G2 phase

  Karen Akopyan, Arne Lindqvist, bioRxiv - Cell Biology 2024

  Quote: ... Aurora B (#3094; Cell Signaling), pLaminA/C (#2026 ...
• Vcam1+ Fibro-adipogenic Progenitors Mark Fatty Infiltration in Chronic Limb Threatening Ischemia

  Qunsheng Dai, et al., bioRxiv - Genomics 2024

  Quote: ... b-catenin (Cell signaling, 8814S), GAPDH (Cell signaling ...
• Prohibitin 2 is a Key Regulator of T Cell Proliferation and Effector Functions

  Johannes F. Vogt, et al., bioRxiv - Immunology 2024

  Quote: ... b-actin (Cell Signaling #4970), HELLS (Cell Signaling #7998) ...
• Remote organ cancer adversely alters renal function and induces kidney injury, inflammation, and fibrosis

  Dana Hammouri, et al., bioRxiv - Physiology 2024

  Quote: ... B-Catenin (Cell signaling, 8480), Vimentin (Cell signaling,5741) ...
• Non-canonical Wnt signaling triggered by WNT2B drives adrenal aldosterone production

  Kleiton S. Borges, et al., bioRxiv - Genetics 2024

  Quote: ... WNT5A/B (Cell Signaling, #2530S) or ...
• Insights into Dentatorubral-Pallidoluysian Atrophy from a new Drosophila model of disease

  Matthew V. Prifti, et al., bioRxiv - Neuroscience 2024

  Quote: ... the tissues were blocked for 2 hours (1xPBS + 0.3% Triton-X + 2% BSA) and incubated overnight in primary antibodies (Cell Signaling Technology, rabbit anti-HA, Catalog # 3724) on rotation at 4°C ...
• CHRM1 is a Druggable Melanoma Target Whose Endogenous Activity is Determined by Inherited Genetic Variation in DOPA Production

  Miriam Doepner, et al., bioRxiv - Cancer Biology 2021

  Quote: ... P-ERK (Cell Signaling Technology, Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204 ...
• Ubiquitin specific protease 1 expression and function in T cell immunity

  Kyla D Omilusik, et al., bioRxiv - Immunology 2021

  Quote: ... Id2 (1:1000; 9-2-8, CalBioeagents or D39E8, Cell Signaling), Id3 (1:1000 ...
• Dopamine ameliorates hyperglycemic memory-induced vascular dysfunction in diabetic retinopathy

  Yeon-Ju Lee, et al., bioRxiv - Biochemistry 2022

  Quote: ... Bcl-2-associated X protein (BAX) (1:1000, Cell Signaling Technology), cytochrome c (1:500 ...
• Vascular Endothelial Growth Factor as an Immediate-Early Activator of UV-induced Skin Injury

  Stella P. Hartono, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and phosphorylation of VEGFR-2 at Y1175 (#2478, Cell Signaling Technology) as previously described (32) ...
• Induction of hyperandrogenism and insulin resistance differentially modulates ferroptosis in uterine and placental tissues of pregnant rats

  Yuehui Zhang, et al., bioRxiv - Physiology 2020

  Quote: ... anti-ERK1/2 antibody (#4695, Cell Signaling Technology, Danver, MA, USA), anti-phospho-ERK1/2 antibody (#9911 ...
• Inhibition of KDM1A activity restores adult neurogenesis and improves hippocampal memory in a mouse model of Kabuki syndrome

  Li Zhang, et al., bioRxiv - Genetics 2020

  Quote: ... anti-p44/42 MAPK(Erk1/2) (Cell Signaling Technologies, catalog #9102), anti-β-Actin (Cell Signaling Technologies ...
• Cell state diversity promotes metastasis through heterotypic cluster formation in melanoma

  Nathaniel R. Campbell, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Antibodies: rabbit anti-hs_TFAP2A (Cell Signaling, #3215, clone C83E10, lot 2), mouse anti-hs_H3 (Cell Signaling ...
• Metabolic Derangement in Polycystic Kidney Disease Mouse Models Is Ameliorated by Mitochondrial-Targeted Antioxidants

  Nastaran Daneshgar, et al., bioRxiv - Pathology 2021

  Quote: ... p44/42 MAPK (Erk1/2) (Cell Signaling Technology, 4695, 1:500) and phospho-p44/42 MAPK (ERK1/2 ...
• PDGFR dimer-specific activation, trafficking and downstream signaling dynamics

  Madison A. Rogers, Katherine A. Fantauzzo, bioRxiv - Cell Biology 2021

  Quote: ... phospho-Erk1/2 (1:1000; Thr202/Thr204; 9101; Cell Signaling Technology); Erk1/2 (1:1000 ...
• The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish

  Alexandra Veloso, et al., bioRxiv - Developmental Biology 2020

  Quote: ... paxillin (#2541S) and ERK1/2 (#9101) were purchased from Cell signaling. Anti-paxillin (610051) ...
• Computational pharmacogenomics screen identifies synergistic statin-compound combinations as anti-breast cancer therapies

  Jenna van Leeuwen, et al., bioRxiv - Cancer Biology 2020

  Quote: ... p44/42 MAPK (ERK1/2) (1:1000, Cell Signaling Technology, 4695), PARP (1:1000 ...
• Hemangiosarcoma cells induce M2 polarization and PD-L1 expression in macrophages

  Kevin Christian M. Gulay, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-p-ERK1/2 antibody (1:1000; Cell Signaling Technology, 4370S), anti-ERK1/2 antibody (1:1000 ...
• ZIP9 is a Druggable Determinant of Sex Differences in Melanoma

  Cristina Aguirre-Portolés, et al., bioRxiv - Cancer Biology 2021

  Quote: ... P-ERK (Cell Signaling Technology, Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204 ...
• Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

  Parishmita Sarma, et al., bioRxiv - Biochemistry 2022

  Quote: ... anti-pERK1/2 (1:5000; Cell Signaling Technology, Cat. no. 9101), and anti-tERK1/2 (1:5000 ...
• Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury

  Lilija Wehling, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and anti-pLATS1/2 (1:200, Cell Signaling Technology, #8654, RRID:AB_10971635). Subsequently ...
• GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

  Christina Wolf, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-PKM1/2 mAb (clone C103A3, 1:1000, Cell Signaling 3582), anti-TOM20 (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... phospho-ERK1/2 (1:1000, Cat#: 4377, Cell Signaling, Danvers, MA), total ERK1/2 (1:1000 ...
• Tendon Cell Deletion of IKKβ/NF-κB Drives Functionally Deficient Tendon Healing and Altered Cell Survival Signaling In Vivo

  Katherine T. Best, et al., bioRxiv - Molecular Biology 2020

  Quote: ... total ERK1/2 (1:1000, Cat#: 9102, Cell Signaling, Danvers, MA), phospho-JNK (1:1000 ...
• Inhibition of IL34 unveils tissue-selectivity and is sufficient to reduce microglial proliferation in chronic neurodegeneration

  Juliane Obst, et al., bioRxiv - Neuroscience 2020

  Quote: ... or phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204, Cell signaling) over night at 4°C ...
• Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome

  Fikri Birey, et al., bioRxiv - Neuroscience 2021

  Quote: ... and Myosin Light Chain 2 (rabbit, 1:1,000, Cell Signaling, 8505S), and Phospho-Myosin Light Chain 2 (Ser19 ...
• Angiocrine IGFBP3 Spatially Coordinates IGF Signaling During Neonatal Cardiac Regeneration

  Shah R. Ali, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-p44/42 MAPK (Erk1/2) (Cell Signaling, 9102S, 1:500), anti-phospho p44/42 MAPK (Erk1/2 ...
• Targeting of MCL-1 in breast cancer associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties

  TL Bonneaud, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 2 μl of anti-MCL-1 antibody (Cell signaling mAb #94296) and 10μl of beads were then used for 200 μg of proteins following manufacturer’s instructions (direct protocol) ...