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401 - 450 of 1131 1 6 Chloropyridazin 3 yl piperidine 4 carboxamide from Selleck Chemicals

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  1-Triacontanol

  1-Triacontanol (n-Triacontanol, Melissyl alcohol, Myricyl alcohol) is a fatty alcohol found in...

  Cat# S5172, SKU# S5172-25mg, 25mg, $97.00 Ask
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  RS-1

  RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is...

  Cat# S8234, SKU# S8234-10mg, 10mg, $97.00 Ask
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  G-1

  G-1 (LNS 8801) is a nonsteroidal and selective agonist of G protein-coupled receptor 30 (GPR30,...

  Cat# S0851, SKU# S0851-5mg, 5mg, $390.00 Ask
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  OF-1

  OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain with Kd of 100 nM and 500 nM, respectively.

  Cat# S7681, SKU# S7681-5mg, 5mg, $97.00 Ask
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  1-Kestose

  1-Kestose (1F-beta-D-Fructosylsucrose), a fructooligosaccharide, could efficiently stimulates...

  Cat# S9109, SKU# S9109-1mg, 1mg, $107.00 Ask
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  TPCA-1

  TPCA-1 (GW683965) is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits...

  Cat# S2824, SKU# S2824-50mg, 50mg, $470.00 Ask
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  Tenovin-1

  Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquitination, and...

  Cat# S8000, SKU# S8000-50mg, 50mg, $270.00 Ask
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  OSMI-1

  OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 μM for full...

  Cat# S9835, SKU# S9835-10mM/1mL, 10mM/1mL, $170.00 Ask
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  Vacuolin-1

  Vacuolin-1 is a potent and cell-permeable inhibitor that blocks the Ca(2+)-dependent exocytosis...

  Cat# S6912, SKU# S6912-5mg, 5mg, $117.00 Ask
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  1-Deoxynojirimycin

  1-Deoxynojirimycin (duvoglustat, moranolin) is a potent α-glucosidase inhibitor and most...

  Cat# S3839, SKU# S3839-25mg, 25mg, $297.00 Ask
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  TPI-1

  TPI-1 (Tyrosine Phosphatase Inhibitor 1) is a potent inhibitor of SHP-1 with IC50 of 40 nM for...

  Cat# S6570, SKU# S6570-5mg, 5mg, $157.00 Ask
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  dCBP-1

  dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP by hijacking the E3...

  Cat# S9889, SKU# S9889-5mg, 5mg, $970.00 Ask
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  RS-1

  RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51. It is...

  Cat# S8234, SKU# S8234-50mg, 50mg, $297.00 Ask
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  1-BCP

  1-BCP (Piperonylic acid piperidide) is a memory-enhancing agent that enhances AMPA-induced currents.

  Cat# S6803, SKU# S6803-5mg, 5mg, $219.00 Ask
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  1-Azakenpaullone

  1-Azakenpaullone (1-Akp) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM,...

  Cat# S7193, SKU# S7193-5mg, 5mg, $339.00 Ask

  Cited in: Patterns of NFkB activation resulting from damage, reactive microglia, cytokines, and growth factors in the mouse retina

  Isabella Palazzo, et al., bioRxiv - Neuroscience 2022

  Quote: ... and a cocktail of three different GSK3β inhibitors (referred to as ABC) which included 1-Azakenpaullone (1-AP; 500 ng/dose; Selleck Chemicals; S7193), BIO (500 ng/dose ...
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  1-Butanol

  1-Butanol occurs naturally as a minor product of the fermentation of sugars and other...

  Cat# S6206, SKU# S6206-25ul, 25ul, $97.00 Ask
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  1-Thioglycerol

  1-Thioglycerol(Mercaptopropanedioltech) is an inhibitor of glycerol kinase activity. It...

  Cat# E2907, SKU# E2907-25mg, 25mg, $79.00 Ask
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  Oncrasin-1

  Oncrasin-1 (Onc-1) is a potent RNA polymerase II inhibitor with antitumor activity that kills...

  Cat# S0780, SKU# S0780-5mg, 5mg, $97.00 Ask
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  Mdivi-1

  Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of...

  Cat# S7162, SKU# S7162-1g, 1g, $970.00 Ask
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  RCM-1

  RCM-1 is a nontoxic inhibitor of Forkhead box M1 (FOXM1) that suppresses goblet cell metaplasia...

  Cat# S6898, SKU# S6898-5mg, 5mg, $237.00 Ask
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  Shield-1

  Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12...

  Cat# S3469, SKU# S3469-5mg, 5mg, $479.00 Ask
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  Alda 1

  Alda 1 is an ALDH2 agonist that activates catalysis for both wild-type ALDH2 (ALDH2*1) and ALDH2*2.

  Cat# S5800, SKU# S5800-5mg, 5mg, $97.00 Ask
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  FSL-1

  FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to...

  Cat# S8428, SKU# S8428-1mg, 1mg, $309.00 Ask
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  RI-1

  RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor with IC50 ranging from 5 to 30 μM.

  Cat# S8077, SKU# S8077-10mg, 10mg, $197.00 Ask
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  Torin 1

  Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM in cell-free assays; exhibits...

  Cat# S2827, SKU# S2827-50mg, 50mg, $670.00 Ask

  Cited in: Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

  Pei-Yun Tsai, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Torin 1 (Selleck Chemicals, S2827).

  » View all citations
• 1-Thioglycerol

  1-Thioglycerol(Mercaptopropanedioltech) is an inhibitor of glycerol kinase activity. It...

  Cat# E2907, SKU# E2907-100mg, 100mg, $197.00 Ask
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  ISO-1

  ISO-1 (MIF Antagonist) is an inhibitor of MIF (Macrophage migration inhibitory factor)...

  Cat# S7732, SKU# S7732-25mg, 25mg, $317.00 Ask
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  BH3I-1

  BH3I-1 is a Bcl-XL-BH3 domain interaction inhibitor with Ki of 2.4 μM (by fluorescence...

  Cat# S8177, SKU# S8177-25mg, 25mg, $397.00 Ask
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  IMR-1

  IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 26 μM.

  Cat# S8280, SKU# S8280-25mg, 25mg, $397.00 Ask
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  PAP-1

  PAP-1 (5-(4-phenoxybutoxy)psoralen), a Kv1.3 antagonist with an EC50 of 2 nM, inhibits the...

  Cat# E0378, SKU# E0378-5mg, 5mg, $159.00 Ask
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  IQ-1

  IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous...

  Cat# S8248, SKU# S8248-50mg, 50mg, $297.00 Ask
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  Mdivi-1

  Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of...

  Cat# S7162, SKU# S7162-50mg, 50mg, $297.00 Ask
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  Shield-1

  Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12...

  Cat# S3469, SKU# S3469-10mM/1mL, 10mM/1mL, $570.00 Ask
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  MZ-1

  MZ-1 is a PROTAC degrader of bromodomain-containing protein 4 (BRD4). MZ-1 binds to the Brd...

  Cat# S8889, SKU# S8889-10mM/1mL, 10mM/1mL, $247.00 Ask
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  Mdivi-1

  Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of...

  Cat# S7162, SKU# S7162-200mg, 200mg, $570.00 Ask
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  1-Azakenpaullone

  1-Azakenpaullone (1-Akp) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM,...

  Cat# S7193, SKU# S7193-2mg, 2mg, $187.00 Ask

  Cited in: Patterns of NFkB activation resulting from damage, reactive microglia, cytokines, and growth factors in the mouse retina

  Isabella Palazzo, et al., bioRxiv - Neuroscience 2022

  Quote: ... and a cocktail of three different GSK3β inhibitors (referred to as ABC) which included 1-Azakenpaullone (1-AP; 500 ng/dose; Selleck Chemicals; S7193), BIO (500 ng/dose ...
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  1-EBIO

  1-EBIO (1-Ethylbenzimidazolinone, 1-Ethyl-2-benzimidazolinone）is an activator of Ca2+-sensitive...

  Cat# E0012, SKU# E0012-5mg, 5mg, $97.00 Ask
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  Nodinitib-1

  Nodinitib-1(ML130) is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM, inhibits...

  Cat# S2863, SKU# S2863-10mM/1mL, 10mM/1mL, $100.00 Ask
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  RPI-1

  RPI-1 inhibits proliferation of human papillary thyroid carcinoma cell line TPC-1 by inducing...

  Cat# E2682, SKU# E2682-5mg, 5mg, $129.00 Ask
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  ISO-1

  ISO-1 (MIF Antagonist) is an inhibitor of MIF (Macrophage migration inhibitory factor)...

  Cat# S7732, SKU# S7732-10mM/1mL, 10mM/1mL, $107.00 Ask
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  M2I-1

  M2I-1 is an inhibitor of Mad2 (mitotic arrest deficient 2) targeting the binding of Mad2 to...

  Cat# S0187, SKU# S0187-5mg, 5mg, $427.00 Ask
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  IQ-1

  IQ-1 enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous...

  Cat# S8248, SKU# S8248-10mg, 10mg, $97.00 Ask
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  1-Aminobenzotriazole

  1-Aminobenzotriazole (ABT, 3-Aminobenzotriazole, 1-Benzotriazolylamine, NSC 114498, NSC 656987)...

  Cat# S6886, SKU# S6886-25mg, 25mg, $97.00 Ask
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  1-Azakenpaullone

  1-Azakenpaullone (1-Akp) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM,...

  Cat# S7193, SKU# S7193-10mM/1mL, 10mM/1mL, $379.00 Ask

  Cited in: Patterns of NFkB activation resulting from damage, reactive microglia, cytokines, and growth factors in the mouse retina

  Isabella Palazzo, et al., bioRxiv - Neuroscience 2022

  Quote: ... and a cocktail of three different GSK3β inhibitors (referred to as ABC) which included 1-Azakenpaullone (1-AP; 500 ng/dose; Selleck Chemicals; S7193), BIO (500 ng/dose ...
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  BTR-1

  BTR-1 induces cytotoxicity in a time- and concentration-dependent manner on leukemia cell line...

  Cat# S0307, SKU# S0307-5mg, 5mg, $317.00 Ask
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  ISO-1

  ISO-1 (MIF Antagonist) is an inhibitor of MIF (Macrophage migration inhibitory factor)...

  Cat# S7732, SKU# S7732-1g, 1g, $1270.00 Ask
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  PRIMA-1

  PRIMA-1 (2,2-Bis(hydroxymethyl)-3-quinuclidinone) is a mutant p53 reactivator. It induces...

  Cat# S7723, SKU# S7723-50mg, 50mg, $397.00 Ask
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  SANT-1

  SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist...

  Cat# S7092, SKU# S7092-10mg, 10mg, $147.00 Ask
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  1-Methylpyrrolidine

  1-Methylpyrrolidine is extensively used in the synthesis of pyrrolidine based ionic liquids.

  Cat# S6216, SKU# S6216-25ul, 25ul, $97.00 Ask
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  HCH6-1

  HCH6-1 is a selective competitive antagonist of formyl peptide receptor 1 (FPR1) and has...

  Cat# S0547, SKU# S0547-5mg, 5mg, $187.00 Ask