N 2 Chloro 5 1 oxo 2 3 pentadecylphenoxy butyl amino phenyl 4 4 dimethyl 3 oxovaleramidefrom Selleck Chemicals

JC-1 (CBIC2, NK 1420), a fluorescent lipophilic carbocyanine dye, is a mitochondrial potential...

Cat# S9784, SKU# S9784-5mg, 5mg, $427.00 Ask

Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM in cell-free assays; exhibits...

Cat# S2827, SKU# S2827-200mg, 200mg, $1870.00 Ask

Cited in: Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

Pei-Yun Tsai, et al., bioRxiv - Cancer Biology 2020

Quote: ... Torin 1 (Selleck Chemicals, S2827).

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Vacuolin-1

Vacuolin-1 is a potent and cell-permeable inhibitor that blocks the Ca(2+)-dependent exocytosis...

Cat# S6912, SKU# S6912-10mM/1mL, 10mM/1mL, $137.00 Ask

BMS-1

BMS-1 is a small-molecule inhibitor of PD-1/PD-L1 interaction with IC50 of 6 nM.

Cat# S7911, SKU# S7911-25mg, 25mg, $497.00 Ask

TPCA-1

TPCA-1 (GW683965) is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits...

Cat# S2824, SKU# S2824-10mg, 10mg, $170.00 Ask

FSL-1

FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to...

Cat# S8428, SKU# S8428-5mg, 5mg, $927.00 Ask

ITD-1

ITD-1 is a potent TGF-β inhibitor. It does not block the kinase activity of either type I...

Cat# S6713, SKU# S6713-10mM/1mL, 10mM/1mL, $117.00 Ask

HA14-1

HA14-1 is a non-peptidic ligand of a Bcl-2 surface pocket with IC50 of ~9 μM.

Cat# S1071, SKU# S1071-50mg, 50mg, $170.00 Ask

Liproxstatin-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

Cat# S7699, SKU# S7699-100mg, 100mg, $997.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... liproxstatin-1 (Selleck Chemicals, #S7699); ferrostatin-1 (Selleck Chemicals ...

TAPI-1

TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors. TAPI-1 is also...

Cat# S7434, SKU# S7434-1mg, 1mg, $270.00 Ask

Cited in: Targeting neuronal activity-regulated neuroligin-3 dependency for high-grade glioma therapy

Humsa S. Venkatesh, et al., bioRxiv - Neuroscience 2017

Quote: ... TAPI-1 at 20uM (ADAM17 inhibitor; S7434; Selleck Chemicals); GI 254023X at 200nM (ADAM10 inhibitor ...

Torin 1

Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM in cell-free assays; exhibits...

Cat# S2827, SKU# S2827-10mg, 10mg, $170.00 Ask

Cited in: Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

Pei-Yun Tsai, et al., bioRxiv - Cancer Biology 2020

Quote: ... Torin 1 (Selleck Chemicals, S2827).

» View all citations

WQ 1

WQ 1 is a high affinity and selective σ1 receptor antagonist with pKi values of 10.85, 6.53 and...

Cat# E0388, SKU# E0388-5mg, 5mg, $227.00 Ask

AMI-1

AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and...

Cat# S7884, SKU# S7884-10mM/1mL, 10mM/1mL, $117.00 Ask

RCM-1

RCM-1 is a nontoxic inhibitor of Forkhead box M1 (FOXM1) that suppresses goblet cell metaplasia...

Cat# S6898, SKU# S6898-25mg, 25mg, $717.00 Ask

BTB-1

BTB-1 is a novel, selective and reversible inhibitor of the mitotic motor protein Kif18A with...

Cat# S6796, SKU# S6796-5mg, 5mg, $97.00 Ask

Stafia-1

Stafia-1 is the first STAT5a inhibitor that inhibits STAT5a (IC50=22.2 μM, Ki=10.9 μM) with at...

Cat# E0485, SKU# E0485-25mg, 25mg, $870.00 Ask

NQDI-1

NQDI 1, an inhibitor of ASK1(apoptosis signal-regulating kinase 1), attenuates acute ischemic...

Cat# S8289, SKU# S8289-50mg, 50mg, $397.00 Ask

Spautin-1

Spautin-1 is a potent and specific autophagy inhibitor, and inhibits the deubiquitinating...

Cat# S7888, SKU# S7888-1g, 1g, $1470.00 Ask

LCS-1

LCS-1 is an inhibitor of superoxide dismutase 1(SOD1) with IC50 of 1.07 μM.

Cat# E2832, SKU# E2832-5mg, 5mg, $70.00 Ask

Necrostatin-1

Necrostatin-1 (Nec-1) is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced...

Cat# S8037, SKU# S8037-10mg, 10mg, $97.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... necrostatin-1 (Selleck Chemicals, #S8037); pepstatin A (Cayman ...

A2ti-1

A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t)...

Cat# E1421, SKU# E1421-5mg, 5mg, $297.00 Ask

NGI-1

NGI-1 is an aminobenzamide-sulfonamide compound that targets both oligosaccharyltransferase...

Cat# S8750, SKU# S8750-10mM/1mL, 10mM/1mL, $99.00 Ask

Liproxstatin-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

Cat# S7699, SKU# S7699-5mg, 5mg, $147.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... liproxstatin-1 (Selleck Chemicals, #S7699); ferrostatin-1 (Selleck Chemicals ...

BMS-1

BMS-1 is a small-molecule inhibitor of PD-1/PD-L1 interaction with IC50 of 6 nM.

Cat# S7911, SKU# S7911-10mM/1mL, 10mM/1mL, $167.00 Ask

SC-1

SC-1 (1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea, STAT3-IN-7), a...

Cat# S0986, SKU# S0986-5mg, 5mg, $427.00 Ask

SANT-1

SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist...

Cat# S7092, SKU# S7092-10mM/1mL, 10mM/1mL, $157.00 Ask

AMI-1

AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 μM and...

Cat# S7884, SKU# S7884-25mg, 25mg, $297.00 Ask

Necrostatin-1

Necrostatin-1 (Nec-1) is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced...

Cat# S8037, SKU# S8037-100mg, 100mg, $270.00 Ask

Cited in: Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

Johnson Ung, et al., bioRxiv - Cancer Biology 2023

Quote: ... necrostatin-1 (Selleck Chemicals, #S8037); pepstatin A (Cayman ...

MID-1

MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction,...

Cat# E0794, SKU# E0794-5mg, 5mg, $209.00 Ask

SANT-1

SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist...

Cat# S7092, SKU# S7092-50mg, 50mg, $570.00 Ask

ISO-1

ISO-1 (MIF Antagonist) is an inhibitor of MIF (Macrophage migration inhibitory factor)...

Cat# S7732, SKU# S7732-5mg, 5mg, $107.00 Ask

Stafia-1

Stafia-1 is the first STAT5a inhibitor that inhibits STAT5a (IC50=22.2 μM, Ki=10.9 μM) with at...

Cat# E0485, SKU# E0485-5mg, 5mg, $290.00 Ask

1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1)

1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-Echinocandin B Hydrochloride (Anidulafungin Nucleus) is...

Cat# E0739, SKU# E0739-5mg, 5mg, $129.00 Ask

ERK5-IN-1

ERK5-IN-1 (XMD17-109) is a potent, and selective ERK5 inhibitor with IC50 of 162 nM.

Cat# S7334, SKU# S7334-25mg, 25mg, $477.00 Ask

DDR1-IN-1

DDR1-IN-1 is a potent and selective discoidin domain receptor 1 (DDR1) receptor tyrosine kinase...

Cat# S7498, SKU# S7498-25mg, 25mg, $447.00 Ask

mTOR inhibitor-1

mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and...

Cat# S0179, SKU# S0179-5mg, 5mg, $257.00 Ask

1-Methoxy PMS

Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is a stable electron-transport...

Cat# S7770, SKU# S7770-25mg, 25mg, $97.00 Ask

Raf inhibitor 1

Raf inhibitor 1 is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-Raf...

Cat# E2651, SKU# E2651-5mg, 5mg, $170.00 Ask

1-Naphthyl acetate

1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages....

Cat# S4804, SKU# S4804-25mg, 25mg, $97.00 Ask

KDM4D-IN-1

KDM4D-IN-1 is a potent inhibitor of KDM4D with an IC50 of 0.41 μM.

Cat# S1059, SKU# S1059-5mg, 5mg, $427.00 Ask

Ginger Extract(1%)

Ginger Extract(1%) is extracted from Zingiber officinale Roscoe, which has antioxidant potential...

Cat# E3634, SKU# E3634-5mg, 5mg, $89.00 Ask

DCLK1-IN-1

DCLK1-IN-1 is a selective, in vivo-compatible chemical probe of the doublecortin like kinase 1...

Cat# S8976, SKU# S8976-10mg, 10mg, $590.00 Ask

CBR-470-1

CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1...

Cat# E1220, SKU# E1220-5mg, 5mg, $79.00 Ask

D-JNKI-1

D-JNKI-1 (AM-111, XG-102, Brimapitide) is a highly and cell-permeable peptide inhibitor of JNK.

Cat# P1106, SKU# P1106-25mg, 25mg, $1109.00 Ask

SLC13A5-IN-1

SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5/NaCT). It...

Cat# S0755, SKU# S0755-25mg, 25mg, $417.00 Ask

Ketohexokinase inhibitor 1

Ketohexokinase inhibitor 1 (PF-06835919, MDK1846) is a potent inhibitor of ketohexokinase (KHK)...

Cat# S0808, SKU# S0808-5mg, 5mg, $570.00 Ask

IWR-1-endo

IWR-1-endo (endo-IWR 1, IWR-1) is a Wnt pathway inhibitor with IC50 of 180 nM in L-cells...

Cat# S7086, SKU# S7086-10mM/1mL, 10mM/1mL, $119.00 Ask

Cited in: Cryo-electron tomography reveals the structural diversity of cardiac proteins in their cellular context

Rahel A. Woldeyes, et al., bioRxiv - Biophysics 2023

Quote: ... and then 5 uM IWR-1 (Selleck Chemicals, S7086) for another 2 days ...

1-NM-PP1

1-NM-PP1 (PP1 Analog II, 1NM-PP1, analogue 9) is a potent inhibitor of Src family kinases with...

Cat# S6383, SKU# S6383-5mg, 5mg, $167.00 Ask

D-JNKI-1

D-JNKI-1 (AM-111, XG-102, Brimapitide) is a highly and cell-permeable peptide inhibitor of JNK.

Cat# P1106, SKU# P1106-5mg, 5mg, $370.00 Ask

ALK inhibitor 1

ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor which can inhibit...

Cat# E2836, SKU# E2836-5mg, 5mg, $249.00 Ask

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