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1 - 50 of 865 citations for Tetratricopeptide repeat protein 14 TTC14 Antibody HRP since 2020

• Functional synapses between small cell lung cancer and glutamatergic neurons

  Anna Schmitt, et al., bioRxiv - Cancer Biology 2023

  Quote: ... The anti–PD-1 antibody RMP1-14 (BioXCell) was administered i.p ...
• SHP2 Inhibition Abrogates Adaptive Resistance to KRAS^G12C-Inhibition and Remodels the Tumor Microenvironment of KRAS-Mutant Tumors

  Carmine Fedele, et al., bioRxiv - Cancer Biology 2020

  Quote: ... α-PD-1 antibody (200 μg; RMP1-14, BioXcell) was used ...
• YAP-controlled MHC-I and CXCL10 expression potentiates antitumor immunity independently of IFNγ signaling

  Linyuan Peng, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or anti- PD1 antibody (clone RMP1-14, BioXCell, BE0146) on days 5 ...
• Immune Checkpoint Blockade Delays Cancer and Extends Survival in Murine DNA Polymerase Mutator Syndromes

  Akshada Sawant, et al., bioRxiv - Cancer Biology 2024

  Quote: ... or Anti-PD1 antibody (RMP-14 clone BioXcell #BE0146) every 5 days ...
• Immune Checkpoint Blockade Delays Cancer and Extends Survival in Murine DNA Polymerase Mutator Syndromes

  Akshada Sawant, et al., bioRxiv - Cancer Biology 2024

  Quote: ... or Anti-PD1 antibody (RMP-14 clone BioXcell #BE0146) and 200 ug of either control IgG (BioXcell #BE0089 ...
• Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma

  Miho Tanaka, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Antibodies used were rat anti-mouse PD-1 IgG2a antibody (RMP1-14, BioXCell), rat anti-CD40 agonist IgG2a antibody (FGK4.5 ...
• S100A8/A9 predicts triple-negative breast cancer response to PIM kinase and PD-1/PD-L1 inhibition

  Lauren R. Begg, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-mouse PD-1 antibody (BioXCell, clone RMP1-14, BE0146), anti-mouse PD-L1 antibody (BioXCell ...
• Non-lytic replicating viral delivery of an IL15 superagonist enhances antitumor immunity and extends survival in glioblastoma

  Alexander F. Haddad, et al., bioRxiv - Cancer Biology 2024

  Quote: ... mice were administered either anti-PD1 antibody (RMP1-14, BioXcell) or isotype control (BioXcell ...
• Complexes Formed by Mixing Tumor-derived Extracellular Vesicles with Polymeric Surfactants for Personalized Therapeutic Vaccine

  Wenfeng Zeng, et al., bioRxiv - Immunology 2022

  Quote: ... Anti-mouse PD-1 (RMP1-14) antibody was purchased from BioXcell.
• Development of A Novel Highly Selective TLR8 Agonist for Cancer Immunotherapy

  Yuxun Wang, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... The anti-PD-1 monoclonal antibody αPD-1 (Clone RMP1-14, Bioxcell) was administered at 10 mg/kg ...
• Cellular selectivity of STING stimulation determines priming of anti-tumor T cell responses

  Bakhos Jneid, et al., bioRxiv - Immunology 2021

  Quote: ... Treatments consisting of 200 µg of αPD1 antibody (clone RMP1-14, BioXcell) or 200 µg isotype control antibody (Rat IgG2a ...
• An immunomechanical checkpoint PYK2 governs monocyte-to-macrophage differentiation in pancreatic cancer

  Wenyan Xie, et al., bioRxiv - Immunology 2024

  Quote: ... or αPD-1 antibody (anti-mouse PD1, clone RMP1-14, BioXCell, US) treatment via intraperitoneal (i.p. ...
• Upregulated PD-1 Signaling is an Important Antagonist to Glomerular Health in Aged Kidneys

  Jeffrey W. Pippin, et al., bioRxiv - Cell Biology 2021

  Quote: ... InVivoMAb anti-mouse PD-1 antibody (RMP1-14, Bio X Cell, Lebanon, NH) was applied every other day at 10ug/ml culture media for 5 days ...
• Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment

  Alba Nicolas-Boluda, et al., bioRxiv - Cancer Biology 2020

  Quote: ... injections of 200 µg of anti–PD-1 antibody (RMP1-14 clone; BioXcell) or isotype control (rat IgG2a ...
• Epigenetic therapy to enhance therapeutic effects of PD-1 inhibition in uveal melanoma

  Vasu R Sah, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 200 μg PD-1-blocking antibody-injected (clone RMP1-14, BioXCell, Lebanon, NH) intraperitoneally twice per week for three weeks ...
• Ribosomal RNA transcription governs splicing through ribosomal protein RPL22

  Wenjun Fan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... or biweekly with mouse anti-PD-1 antibody RMP1-14 (BioXcell, cat # BE0146) 10 mg/kg ...
• Gut microbiota dysbiosis induced by brain tumor modulates the efficacy of immunotherapy

  Hyeon Cheol Kim, et al., bioRxiv - Microbiology 2024

  Quote: ... we injected 200 μg of anti-PD-1 blocking antibody (RMP1-14; BioXcell) into mice intraperitoneally on days 10 ...
• Rapid metabolic regulation of a novel arginine methylation of KCa3.1 attenuates T cell exhaustion

  Piyush Sharma, et al., bioRxiv - Immunology 2024

  Quote: ... The mice were given either anti-PD1 antibody (RMP1-14, Bio X Cell) or rat IgG2a (2A3 ...
• Reprogramming the genome of M13 bacteriophage for all-in-one personalized cancer vaccine

  Shengnan Huang, et al., bioRxiv - Bioengineering 2024

  Quote: ... Anti-mouse PD-1 antibodies (100 μg, clone RMP1-14, BioXcell, 1× PBS) were administered on day 2 and day 4 following each vaccination treatment ...
• PD-1 checkpoint blockade disrupts CD4 T cell regulated adaptive B cell tolerance to foreign antigens

  Chad R. Dufaud, et al., bioRxiv - Immunology 2021

  Quote: ... 300µg anti-mouse PD-1 antibody (clone J43, 29F.1A12 or RMP1-14, BioXcell) was administered intraperitoneal (IP) ...
• Immunofilaments Provide a Nanoscale Platform for In Vivo T Cell Expansion and Cancer Immunotherapy

  Lea Weiss, et al., bioRxiv - Immunology 2022

  Quote: ... 200 μg InVivoMab rat-anti-mouse PD-1 antibody (clone: RMP1-14, BioXCell, BE0146) was injected in InVivoPure pH 7.0 Dilution Buffer (BioXCell ...
• A lymphoid tissue chemokine checkpoint prevents loss of CD8⁺ T cell functionality

  Lukas M. Altenburger, et al., bioRxiv - Immunology 2024

  Quote: ... (Mel-14, BioXcell, BE0021) 3 h post T cell transfer to prevent further homing and to synchronize the initiation of TN-DC interaction ...
• Detecting Early Response to Immune Checkpoint Blockade by Multimodal Molecular Imaging

  Yu Saida, et al., bioRxiv - Cancer Biology 2020

  Quote: ... with 200 μg of ◻PD-L1 (10F.9G2) or αPD-1 (RMP1-14) or αCTLA-4 (9H10) antibody or with isotype control antibodies (all from BioXcell) on days 9 ...
• PD-1-induced T cell exhaustion is controlled by a Drp1-dependent mechanism

  Luca Simula, et al., bioRxiv - Immunology 2021

  Quote: ... clone RMP1-14 (Bioxcell, BE0146) or 150µg InVivoMab rat IgG2a isotype control ...
• Targeting macrophages with CAR-T cells delays solid tumor progression and enhances anti-tumor immunity

  Alfonso R. Sánchez-Paulete, et al., bioRxiv - Immunology 2021

  Quote: ... Anti-PD1 (RMP1-14, BioXCell) was diluted in PBS to a concentration of 1 mg/ml for intraperitoneal administration of 100 ug ...
• Peptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells

  Ellen J.K. Xu, et al., bioRxiv - Immunology 2024

  Quote: ... aPD1 (clone RMP1-14, BioXCell) was administered at a 150ug dose in endotoxin-free PBS delivered i.p ...
• Dry Powders for Inhalation Containing Monoclonal Antibodies Made by Thin-Film Freeze-Drying

  Stephanie Hufnagel, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... InVivoMAb anti-mouse PD-1 clone RMP1-14 monoclonal antibodies (mAbs) were from BioXCell (Lebanon, NH). SuperBlock™ blocking buffer in PBS (10 mM) ...
• SMARCA4 mutation induces tumor cell-intrinsic defects in enhancer landscape and resistance to immunotherapy

  Yawen Wang, et al., bioRxiv - Immunology 2024

  Quote: ... Treatment with 200 μg rat anti mouse PD-1 IgG2a antibody (RMP1-14, Bio X Cell) or corresponding isotype control antibody in 100 μl PBS was administered to each mouse 3 time a week ...
• KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response

  Casey R. Ager, et al., bioRxiv - Immunology 2023

  Quote: ... Anti-PD-1 (RMP1-14 IgG2a,κ) or Rat IgG2a isotype antibody (Bio X Cell; Lebanon, NH) was diluted in sterile PBS and administered by intraperitoneal (IP ...
• Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumors

  Samarth Hegde, et al., bioRxiv - Immunology 2024

  Quote: ... Mice were administered 100 ug of anti-PD-1 neutralizing antibody (BioXcell Clone RMP1-14, Cat #BE0146) i.v ...
• Cancer therapy via neoepitope-specific monoclonal antibody cocktails

  Colin J. Hartman, et al., bioRxiv - Immunology 2024

  Quote: The ICB antibodies used were rat anti-mouse PD-1 (Bio X Cell BE0146, Clone RMP1- 14) and mouse anti-mouse CTLA-4 (Bio X Cell BE0164 ...
• Secreted antigen A peptidoglycan hydrolase is essential for Enterococcus faecium cell separation and priming of immune checkpoint inhibitor therapy

  Steven Klupt, et al., bioRxiv - Microbiology 2024

  Quote: ... 11 and 14 by intraperitoneal injection in 200 μL antibody buffer solution (BioXCell, PH 7.0 dilution buffer). Mice were euthanized with CO2 asphyxiation when the tumors larger than 1.5 cm3 or any ulceration or lesioning developed.
• Integrin αvβ8 on T cells is responsible for suppression of anti-tumor immunity in multiple syngeneic models and is a promising target for tumor immunotherapy

  Eswari Dodagatta-Marri, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-PD-1 (RMP1-14, BioXcell) or isotype control 2A3_rat IgG (BioXcell ...
• Immune Selection Pressure Contributes to Pancreatic Cancer Immune Evasion

  Reham Ajina, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Anti-PD1 (clone: RMP1-14, BioXcell) was used at a dose of 200 μg/injection twice per week ...
• An mRNA-encoded, long-lasting Interleukin-2 restores CD8⁺ T cell neoantigen immunity in MHC class I-deficient cancers

  Jan D. Beck, et al., bioRxiv - Immunology 2023

  Quote: ... αPD-1 (clone RMP1-14, BioXCell) or αCTLA4 antibody (clone 9D9 ...
• Recombinant single-cycle influenza virus as a new tool to augment antitumour immunity with immune checkpoint inhibitors

  Matheswaran Kandasamy, et al., bioRxiv - Immunology 2021

  Quote: ... immunized mice were also received i.p injection of anti PD-1 antibody (12.5 mg/kg, RMP1-14, BioXCell) or isotype antibody ...
• Harnessing Immunotherapy to Enhance the Systemic Anti-Tumor Effects of Thermosensitive Liposomes

  Maximilian Regenold, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Anti-PD-1 antibody was purchased from Bio X Cell (RMP1-14, Bio X Cell, Lebanon, NH, USA). Sodium sucrose octasulfate (Na8SOS ...
• Upregulated PD-1 Signaling is an Important Antagonist to Glomerular Health in Aged Kidneys

  Jeffrey W. Pippin, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-PD-1 antibody-injected group (n=12) that received weekly IP injections of InVivoMAb anti-mouse PD-1 antibody (RMP1-14, Bio X Cell, Lebanon, NH) at 12 mg/kg for 8 weeks ...
• Ivermectin converts cold tumors hot and synergies with immune checkpoint blockade for treatment of breast cancer

  Dobrin Draganov, et al., bioRxiv - Immunology 2020

  Quote: ... Anti-PD-1 (clone RMP1-14, BioXCell) was administered at 10 mg/kg by intraperitoneal injection in 50 µL sterile PBS ...
• SLIT2-ROBO signaling in tumor-associated microglia/macrophages drives glioblastoma immunosuppression and vascular dysmorphia

  Luiz Henrique Geraldo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... For anti-PD1 (clone RMP1-14, BioXCell) and anti-4-1BB (clone LOB12.3 ...
• Blockade of LAG-3 in PD-L1-deficient mice enhances clearance of blood stage malaria independent of humoral responses

  Raquel Furtado, et al., bioRxiv - Immunology 2020

  Quote: ... or anti-PD-1 (RMP1-14, BioXcell) blocking Abs were injected i.v ...
• Second generation of LNP based mRNA vaccine leads to a T cell–inflamed tumor microenvironment favorable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumor model

  Carole Fournier, et al., bioRxiv - Immunology 2024

  Quote: ... anti-PD-1 (clone RMP1-14, BioXCell) or its isotype control antibody (clone 2A3 ...
• Lymph node-targeted vaccine boosting of TCR-T cell therapy enhances anti-tumor function and eradicates solid tumors

  Dylan J. Drakes, et al., bioRxiv - Immunology 2022

  Quote: ... mice were rechallenged with 5×105 B16F10 GFP-LUC cells on day 75 post T cell transfer with or without intraperitoneal injection of 250 μg anti-Thy1.1 antibody (Days −7, 0, 7, 14, 21, 28, 35) (BioXCell) to deplete adoptively transferred pmel-1 T cells that are Thy1.1 expressing ...
• RORγ bridges cancer-driven lipid dysmetabolism and myeloid immunosuppression

  Augusto Bleve, et al., bioRxiv - Immunology 2023

  Quote: ... MN/MCA1-bearing mice were intraperitoneally injected with 100 μg of anti-PD-1 antibody (BioXcell, Clone RPM1-14), twice a week ...
• Interferon-γ driven differentiation of monocytes into PD-L1⁺ and MHC II⁺ macrophages and the frequency of Tim-3⁺ tumor-reactive CD8⁺ T cells within the tumor microenvironment predict a positive response to anti-PD-1-based therapy in tumor-bearing mice

  Jelena Gabrilo, et al., bioRxiv - Immunology 2024

  Quote: Mice were treated intraperitoneally (i.p) with anti-PD-1 anti-mouse monoclonal antibody (clone RMP1-14, either purchased from BioXcell, USA ...
• The membrane-associated ubiquitin ligase MARCHF8 promotes cancer immune evasion by degrading MHC class I proteins

  Mohamed I. Khalil, et al., bioRxiv - Cancer Biology 2024

  Quote: ... C57BL/6J mice were intraperitoneally injected with 200 µg of an anti-PD-1 antibody (BioXcell, clone RMP1-14) every three days for four times starting from 24 days post-injection when the average tumor size in the mice injected with mEERL/scr cells reached 200 mm3 ...
• Human Rhinoviruses: a novel class of oncolytic virus

  William J Burnett, et al., bioRxiv - Immunology 2023

  Quote: ... The αPD-1 antibody (clone RMP1-14; BE0146) and the isotype control antibody (clone 2A3; BE0089) were obtained from Bio X Cell (West Lebanon, NH, USA). αPD-1 and isotype control antibodies were delivered systemically by IP injection on days 1 ...
• Novel Kras-mutant murine models of non-small cell lung cancer possessing co-occurring oncogenic mutations and increased tumor mutational burden

  Ramin Salehi-Rad, et al., bioRxiv - Cell Biology 2020

  Quote: ... mice bearing ~50mm3 tumors were randomized and treated with 200 μg of anti-PD-1 antibody (BioXcell, Clone RMP1-14) or isotype control via IP injections three times weekly for 4 doses ...
• IFNA pathway drives the more aggressive phenotype of KRAS^G12D-mutant pancreatic ductal adenocarcinomas via IFNAR1/STAT3 activation

  Koetsu Inoue, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and anti-mouse PD-1 antibodies (clone RMP1-14, 10 mg/kg, 6 doses, every 3 days) were purchased from BioXcell. All drug treatments were administered intraperitoneally (i.p.).
• Vaccination generates functional progenitor tumor-specific CD8 T cells and long-term tumor control

  Carlos R. Detrés Román, et al., bioRxiv - Cancer Biology 2024

  Quote: Anti-PD1 (clone RMP1-14) and anti-PDL1 (clone 10.F.9G2) antibodies or isotype control (clone LTA-2) were purchased from BioXcell. Antibodies were diluted in 1X sterile PBS and injected i.p ...