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51 - 100 of 257 citations for Rat High Mobility Group Protein B1 HMGB1 ELISA Kit since 2019

• Gut regulatory T cells mediate immunological tolerance in Salmonella-infected superspreader hosts by suppressing cytotoxic activity of T cells

  LM Massis, et al., bioRxiv - Immunology 2021

  Quote: ... or isotype-matched control antibody (rat IgG2a isotype control, anti-trinitrophenol, BP0089; rat IgG2b isotype control, anti-keyhole limpet hemocyanin, BE0090, BioXcell) were diluted in PBS and administered on days 22 ...
• The Role of IgG Subclass in Antibody-Mediated Protection against Carbapenem-Resistant Klebsiella pneumoniae

  Michael P. Motley, et al., bioRxiv - Immunology 2020

  Quote: ... mice were injected intraperitoneally with 225ug of Rat anti-mouse Ly6G (1A8) or a control Rat anti-mouse IgG2a (2A3) (BioXcell). Neutrophil depletion was confirmed previously using flow cytometry of lung homogenates (Ly6G+ ...
• Protective function and differentiation cues of brain-resident CD8+ T cells during immune surveillance of chronic latent Toxoplasma gondii infection

  Rémi Porte, et al., bioRxiv - Immunology 2024

  Quote: ... Control mice were injected with the same amount of isotype control rat antibodies (rat IgG1, clone HRPN, cat # BX-BE0088 from BioXCell and rat IgG2b ...
• Cancer cell CCR2 orchestrates suppression of the adaptive immune response

  Miriam R. Fein, et al., bioRxiv - Cancer Biology 2019

  Quote: ... or control rat IgG2b antibody (Bio X Cell) (Winograd et al. ...
• Detection of incipient pancreatic cancer with novel tumor-specific antibodies in mouse models

  Tobiloba E. Oni, et al., bioRxiv - Cancer Biology 2020

  Quote: Radiolabeling of Rat IgG2A (BioXcell, cat. no. BE0089), TOBi85 and TOBi89 with 89Zr-DFO was performed as previously described [43-45] ...
• Dietary methionine restriction impairs anti-tumor immunity through gut microbiota

  Ming Ji, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Isotype-matched control antibody rat IgG2a (BioXCell, BE0089) and rat anti-PD1 antibody (BioXCell ...
• Combined Inhibition of SHP2 and CXCR1/2 Promotes Anti-Tumor T Cell Response in NSCLC

  Kwan Ho Tang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 400ug of rat IgG2b (Clone LTF-2, Bioxcell), anti-mouse CD4 antibody (Clone GK1.5 ...
• The Siglec-sialic acid-axis is a target for innate immunotherapy of glioblastoma

  Philip Schmassmann, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and isotype control (rat IgG2a, clone 2A3, BioXcell) were administered at 10 mg kg-1 i.p ...
• NR4A3 deficiency in CD8⁺ T cells improves adoptive T cell therapy of cancer

  Livia Odagiu, et al., bioRxiv - Immunology 2023

  Quote: ... or its isotype (BioXcell or Leinco; Rat IgG2b) control at day 7 ...
• Context-specific GITR agonism potentiates anti-PD-L1 and CD40-based immuno-chemotherapy combination in heterogeneous pancreatic tumors

  Chanthirika Ragulan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or rat IgG2b isotype control (Cat - #BE0090, BioXCell); for combination treatment ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... rat IgG1 isotype control (BioXcell, HPRN, Cat #BE0088), rat IgG2b isotype control (BioXcell ...
• Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer

  Sharon L. Freshour, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Rat IgG2b (BioXcell, catalog #BE0090, clone LTF-2) was used as isotype control for anti-CD4.
• Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma

  Miho Tanaka, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rat anti-CD40 agonist IgG2a antibody (FGK4.5, BioXCell), and rat IgG2a isotype control (2A3 ...
• The physical form of microbial ligands bypasses the need for dendritic cell migration to stimulate adaptive immunity

  Francesco Borriello, et al., bioRxiv - Immunology 2020

  Quote: ... 50 μg/mouse) and their respective isotype controls rat IgG2a (2A3) and rat IgG1 (HRPN) were purchased from Bio X Cell.
• Protective function and differentiation cues of brain-resident CD8+ T cells during immune surveillance of chronic latent Toxoplasma gondii infection

  Rémi Porte, et al., bioRxiv - Immunology 2024

  Quote: ... Control mice were injected with the same amount of isotype control rat antibodies (rat IgG1, clone HRPN, cat # BX-BE0088 from BioXCell and rat IgG2b, clone LTF-2, cat # BX-BP0090 from BioXCell respectively).
• The Injury Response to DNA Damage Promotes Anti-Tumor Immunity

  Ganapathy Sriram, et al., bioRxiv - Cancer Biology 2020

  Quote: ... groups also received intra-peritoneal injections of 200 µg each of anti-PD1 (clone RMP1-14, BioXCell) and anti-CTLA4 (clone 9D9 ...
• MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer

  Manu Prasad, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and αPD-1 (rat anti-mouse PD-1, BE0146-25 -clone RMP1-14) and IgG (rat anti-mouse IgG2a, BE0089-25) from Bio X Cell were used at a concentration of 100 µg/mouse ...
• LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency

  Marie N. O’Connor, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 200 μg rat anti-mouse PD1 (Bio X Cell) or 200 μg rat IgG2a isotype control (Bio X Cell) ...
• DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy

  Louise A. Baldwin, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Rat IgG (BE0089) all from BioXCell (Lebanon, NH, USA). Antibodies were given every 2-3 days from day 10 after tumour implantation for the EMT6 model and following resection of primary tumour on day 15 for the 4T1 model.
• Inhibition of IL34 unveils tissue-selectivity and is sufficient to reduce microglial proliferation in chronic neurodegeneration

  Juliane Obst, et al., bioRxiv - Neuroscience 2020

  Quote: ... rat monoclonal CSF1R-blocking antibodies (BE0213, Bio X Cell) and rat monoclonal IL-34 antibodies (MAB5195 ...
• GABAergic neuronal IL-4R mediates T cell effect on memory

  Zhongxiao Fu, et al., bioRxiv - Neuroscience 2021

  Quote: ... or isotype control antibody (LTF-2, rat IgG2b, BioXCell). To ensure continuous depletion ...
• Lomitapide, a cholesterol-lowering drug, is an anticancer agent that induces autophagic cell death via inhibiting mTOR

  Boah Lee, et al., bioRxiv - Cancer Biology 2021

  Quote: ... or rat IgG2a isotype control (clone 2A3, BioXCell, BE0089) were administered on days 1 ...
• Cellular selectivity of STING stimulation determines priming of anti-tumor T cell responses

  Bakhos Jneid, et al., bioRxiv - Immunology 2021

  Quote: ... or 200 µg isotype control antibody (Rat IgG2a, BioXcell) were diluted in PBS at 1 mg/ml and administered by intra-peritoneal (i.p. ...
• B cell receptor induced IL-10 production from neonatal CD19+CD43- cells depends on STAT5 mediated IL-6 secretion

  Jiro Sakai, et al., bioRxiv - Immunology 2022

  Quote: ... or InVivoMAb anti-mouse/rat IL-1β (B122, BioXcell) for the indicated duration ...
• Cellular sources and targets of type I interferons that drive susceptibility to tuberculosis

  Dmitri I. Kotov, et al., bioRxiv - Immunology 2022

  Quote: ... or rat IgG2b isotype control antibody (LTF-2, BioXCell) in 200 μL PBS via intraperitoneal injection57 ...
• Selective targeting of α₄β₇/MAdCAM-1 axis suppresses liver fibrosis by reducing proinflammatory T cell recruitment to the liver

  Biki Gupta, et al., bioRxiv - Immunology 2023

  Quote: ... or rat IgG2a isotype antibody (Bioxcell, West Lebanon, NH) for four weeks.
• Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in KEAP1 mutant lung cancer

  Ray Pillai, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or isotype control (rat IgG2a, LTF-2, BioXcell BE0090) was administered 150 ug intraperitoneally twice a week once tumor burden was established by bioluminescence ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... rat IgG2b isotype control (BioXcell, LTF-2, Cat #BE0090), anti-mouse IFNγ (BioXcell ...
• Rapid establishment of a tumor-retained state curtails the contribution of conventional NK cells to anti-tumor immunity in solid cancers

  Isaac Dean, et al., bioRxiv - Immunology 2023

  Quote: ... or InVivoMab rat IgG2a isotype control (BioXCell, 2A3, 400μg) in PBS via intraperitoneal injection every 3 days beginning on day 6 post tumor engraftment ...
• Pro-resolution lipid mediator maresin-1 ameliorates inflammation, promotes neuroprotection, and prevents disease progression in experimental models of multiple sclerosis

  Insha Zahoor, et al., bioRxiv - Neuroscience 2023

  Quote: ... Controls received an isotype-matched rat IgG1 (BioXCell # BE0088) following the same protocol Clinical readout was taken as clinical score followed by euthanizing mice at 21 days pdi.
• PD-1 blockade-driven anti-tumor CD8⁺ T cell immunity requires XCR1⁺ dendritic cells

  Tianyang Mao, Eric Song, Akiko Iwasaki, bioRxiv - Immunology 2020

  Quote: ... or 200 µg isotype-matched control antibody (Rat IgG2a, BioXCell) were given intraperitoneally on day 11 ...
• Tertiary lymphoid structures induced by CXCL13-producing CD4⁺ T cells increase tumor infiltrating CD8⁺ T cells and B cells in ovarian cancer

  Masayo Ukita, et al., bioRxiv - Immunology 2021

  Quote: ... and Rat IgG antibody (clone LFT-2, Bio X Cell) were used as negative controls.
• LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency

  Marie N. O’Connor, et al., bioRxiv - Cancer Biology 2020

  Quote: ... or 200 μg rat IgG2a isotype control (Bio X Cell). Mice were dosed by intraperitoneal injection commencing on day 3 and antibody administration was repeated every 3 days until the end of the study ...
• Distinct cDC subsets co-operate in CD40 agonist response while suppressive microenvironments and lack of antigens subvert efficacy

  Aleksandar Murgaski, et al., bioRxiv - Cancer Biology 2021

  Quote: ... agonist antibody or rat IgG2a isotype control (clone 2A3; BioXCell) was administered intraperitoneally (IP ...
• Testicular macrophages are recruited during a narrow time window by fetal Sertoli cells to promote organ-specific developmental functions

  Xiaowei Gu, Anna Heinrich, Tony DeFalco, bioRxiv - Developmental Biology 2022

  Quote: ... or rat IgG2a isotype control (Bio X Cell, clone 2A3) as previously described (8 ...
• Estrogen exacerbates mammary involution through neutrophil dependent and independent mechanism

  Chew Leng Lim, et al., bioRxiv - Developmental Biology 2020

  Quote: ... or rat monoclonal anti-mouse Ly6G antibody (clone 1A8, BioXCell) via intraperitoneal injection ...
• IL-4-induced hysteresis in naïve T cell activation

  Alexandre P. Meli, et al., bioRxiv - Immunology 2020

  Quote: ... or Rat IgG1 isotype control (clone HRPN, Bio X Cell). The first dose was administered 2 days prior to infection and mice were dosed every 2 days thereafter until sacrificed.
• Acute inflammation, mediated by lung neutrophils, confers enhanced protection against Mycobacterium tuberculosis infection in mice

  Tucker J. Piergallini, et al., bioRxiv - Immunology 2021

  Quote: ... or its isotype control rat IgG2a (clone 2A3, BP0089, BioXCell) in 1x PBS were administered via the IP route to LPS/saline mice ...
• Cutaneous Wounds in Mice Lacking Tumor Necrosis Factor-stimulated Gene-6 Exhibit Delayed Closure and an Abnormal Inflammatory Response

  Sajina Shakya, et al., bioRxiv - Physiology 2020

  Quote: ... rat monoclonal TNFα (1 μg/ml; BioXCell, West Lebanon, NH); or rabbit anti-mouse Actin (1:1000 ...
• Decoding commensal-host communication through genetic engineering of Staphylococcus epidermidis

  Y. Erin Chen, et al., bioRxiv - Microbiology 2019

  Quote: ... or rat IgG2b isotype control antibody (clone LTF-2, BioXCell) every other day ...
• A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndrome

  Tomoki Yoshikawa, et al., bioRxiv - Microbiology 2020

  Quote: ... Rat anti-keyhole limpet hemocyanin mAb clone LTF-2 (BioXCell) was used as the control antibody ...
• Distinct cDC subsets co-operate in CD40 agonist response while suppressive microenvironments and lack of antigens subvert efficacy

  Aleksandar Murgaski, et al., bioRxiv - Cancer Biology 2021

  Quote: ... followed by 150 µg mouse anti-RAT (clone MAR18.5; BioXCell) administered IP in volumes of 100 µL HBSS ...
• Lomitapide, a cholesterol-lowering drug, is an anticancer agent that induces autophagic cell death via inhibiting mTOR

  Boah Lee, et al., bioRxiv - Cancer Biology 2021

  Quote: ... or a rat IgG2a isotype control (clone 2A3, BioXCell, BE0089) were administered on days 1 ...
• Cellular selectivity of STING stimulation determines priming of anti-tumor T cell responses

  Bakhos Jneid, et al., bioRxiv - Immunology 2021

  Quote: ... or 200 µg of isotype control antibody (Rat IgG2a, BioXcell) two times prior and four times after i.t ...
• Early detection of cerebrovascular pathology and protective antiviral immunity by MRI

  Li Liu, et al., bioRxiv - Neuroscience 2021

  Quote: ... and isotype control (rat IgG2a) antibodies were purchased from BioXcell. Mice were treated with a combination of 500 μg anti-LFA-1 and 500 μg anti-VLA-4 ...
• The Streptococcus pyogenes hyaluronic acid capsule promotes experimental nasal and skin infection by preventing neutrophil-mediated clearance

  Jacklyn R. Hurst, et al., bioRxiv - Microbiology 2022

  Quote: ... Control mice received rat IgG2a clone 2A3 (BioXCell, NH, USA). Depletion of circulating neutrophils has been confirmed in previous studies using flow cytometry of Ly6G+ expressing populations in blood [47,73,74] ...
• Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer

  Sharon L. Freshour, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 250 μg/mouse rat IgG2a (BioXcell, catalog #BE0089, clone 2A3) and 200 μg/mouse IgG2b (BioXcell ...
• CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance

  Yu Li, et al., bioRxiv - Immunology 2023

  Quote: ... Ter119+ cells using Rat anti-mouse antibodies (BioXcell, NH, USA) and Dynabeads™ sheep anti-rat IgG beads (Invitrogen ...
• Utilization of a Histoplasma capsulatum zinc reporter reveals the complexities of fungal sensing of metal deprivation

  Logan T. Blancett, et al., bioRxiv - Microbiology 2023

  Quote: ... with 200 µg of isotype control mAb rat IgG1a (BioXCell), or 200 µg of 5A1 mAb to M-CSF (Bio X-cell ...
• Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

  Karoline Strobl, et al., bioRxiv - Immunology 2023

  Quote: ... or InVivoMab rat IgG2b isotype control (clone LTF-2, BioXCell) in respective concentrations for 4 weeks.