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251 - 300 of 396 citations for pVectOZ GFP Transfection control since 2019

• TGF-β-dependent Lymphoid Tissue Residency of Stem-like T cells Limits the Response to Tumor Vaccine

  Guo Li, et al., bioRxiv - Immunology 2021

  Quote: ... mice were injected with rat anti-mouse PD-L1 or isotype control (BioXcell) (200 μg per injection ...
• Loss of Rnf43 accelerates Kras-mediated neoplasia and remodels the tumor immune microenvironment in pancreatic adenocarcinoma

  Abdel Nasser Hosein, et al., bioRxiv - Cancer Biology 2021

  Quote: ... or InVivoPlus Syrian hamster IgG isotype control antibody (Cat# BP0087; Bio X Cell). All antibodies were diluted in InVivoPure™ pH 7.0 Dilution Buffer (Bio X Cell ...
• Context-dependent triggering of STING-interferon signaling by CD11b agonists supports anti-tumor immunity in mouse models and human cancer patients

  Xiuting Liu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Control mice were treated with same doses/volume of IgG (clone HRPN, BioXCell) and control liposomes (or PBS as indicated ...
• TCF-7 is dispensable for anti-tumor response but required for persistent function of mature CD8 T cells

  Rebecca Harris, et al., bioRxiv - Immunology 2022

  Quote: ... or rat IgG1 isotype control antibody (10 μg/mL, Bio X Cell #BE0334) was added and incubated for 30 minutes before washing and plating ...
• Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease

  Josef Leibold, et al., bioRxiv - Cancer Biology 2022

  Quote: ... or the respective isotype control (Bio X Cell; BE0290; Bio X Cell; BE0090) was given twice per week by IP injection.
• Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease

  Josef Leibold, et al., bioRxiv - Cancer Biology 2022

  Quote: ... or the respective isotype control (Bio X Cell; BE0290; Bio X Cell; BE0090) was given twice per week by IP injection.
• The adenosine 2a receptor and TIM3 directly inhibit killing of tumor cells by cytotoxic T lymphocytes through interference with cytoskeletal polarization

  Grace L. Edmunds, et al., bioRxiv - Immunology 2021

  Quote: ... 70% vol/vol PBS) +/− 100μg/mouse isotype control (Rat IgG2a, 2A3, BioXcell InVivoMAb)(51) ...
• Design of a systemic small molecule clinical STING agonist using physics-based simulations and artificial intelligence

  Bryce K. Allen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Cluster 1 was pretreated with Isotype IgG control antibody (MAb rat IgG2β, BioXcell) and cluster 2 was pretreated with anti-mouse CD8α antibody (MAb anti-mouse CD8α antibody ...
• Blimp-1 is essential for Th2 cell development and allergic asthma

  Kun He, et al., bioRxiv - Immunology 2020

  Quote: ... Blocking antibodies (IL-21R, IL-10R and IgG control) were purchased from BioXCell. CD90 Microbeads were from Miltenyi Biotec ...
• Regulation of heterotopic ossification through local inflammatory monocytes in a mouse model of aberrant wound healing

  Michael Sorkin, et al., bioRxiv - Immunology 2019

  Quote: ... or anti-SIRPα/isotype control (Bioxcell 100ug i.p. on days -2 and 0).
• PD-L1 – PD-1 interactions limit effector Treg cell populations at homeostasis and during infection

  J.A. Perry, et al., bioRxiv - Immunology 2020

  Quote: ... while control mice were treated with the IgG2b isotype (clone: LTF-2, BioXcell). Antibody injections were performed one day prior to infection and repeated every 72 hours until indicated for acute or chronic infection studies.
• Microbial activation converts neutrophils into anti-tumor effectors

  Andrew O. Yam, et al., bioRxiv - Immunology 2020

  Quote: ... or rat IgG2a isotype control clone 2A3 (Bio X Cell Cat# BE0089, RRID:AB_1107769). Twenty-four hours later 4-10×106 S ...
• CD39⁺PD-1⁺CD8⁺ T cells mediate metastatic dormancy in breast cancer

  Paulino Tallón de Lara, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Control mice were injected with 500 µg rat anti-Trinitrophenol (clone 2A3, BioXCell). Antibodies were purified from hybridoma culture supernatant using protein G Sepharose 4 Fast Flow (Sigma) ...
• Carbon ion irradiation plus CTLA4 blockade elicits therapeutic immune responses in a murine tumor model

  Laura Hartmann, et al., bioRxiv - Immunology 2022

  Quote: ... or rat IgG2b isotype control (all from Bio X Cell, West Lebanon, USA). Mice received three injections of checkpoint blocking antibodies three days apart.
• Melanoma-intrinsic NR2F6 activity regulates anti-tumor immunity

  Hyungsoo Kim, et al., bioRxiv - Cancer Biology 2022

  Quote: ... while controls were treated with 200 µg/mouse IgG [rat IgG2b (BE0090, BioXcell)] ...
• Cytomegalovirus infection in newborn mice alters cerebellar development by lengthening G1/S phases of cerebellar granule cell precursors during postnatal cerebellar development

  Cathy Yea Won Sung, et al., bioRxiv - Developmental Biology 2022

  Quote: ... injection with InVivoMAb rat IgG1 Isotype control anti-trinitrophenol (TNP) (BioXCell, Lebanon, NH) or InVivoMAb anti-mouse TNFα neutralizing antibody (Rat IgG1 ...
• IL-12/18/21 pre-activation enhances the anti-tumor efficacy of expanded γδT cells and overcomes resistance to anti-PD-L1 treatment

  Huey Yee Teo, et al., bioRxiv - Immunology 2022

  Quote: ... 100µg InVivoMAb rat IgG2b isotype control (LTF-2, Bio X Cell, Lebanon, NH) or InVivoMAb anti-mouse PD-L1 (B7-H1 ...
• SARS-CoV-2 ORF8 is a viral cytokine regulating immune responses

  Masako Kohyama, et al., bioRxiv - Microbiology 2022

  Quote: ... or irrelevant control anti-human MHC class II Ab (M5, Bio X Cell) was added to the cells 2h before stimulation.
• A Type 2 Innate Lymphoid Cell-Interleukin 9 Circuit Induces Paneth Cell Metaplasia and Small Intestinal Remodeling

  Cheng-Yin Yuan, et al., bioRxiv - Immunology 2022

  Quote: ... Mouse IgG1 was used as an isotype control antibody (BioXCell, West Lebanon, NH). Anti-CD4 (clone GK1.5 ...
• Intratumor Childhood Vaccine-Specific CD4⁺ T cell Recall Coordinates Antitumor CD8⁺ T cells and Eosinophils

  Michael C. Brown, et al., bioRxiv - Immunology 2022

  Quote: ... and CD40 (Clone FGK4.5) or isotype control (Clone 2A3) were purchased from BioXcell and were delivered intraperitoneal (i.p. ...
• Both CD8 and CD4 T cells contribute to immunosurveillance preventing the development of neoantigen-expressing autochthonous sarcomas

  Jonathon E. Himes, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and/or isotype control (InVivoMAb rat IgG2b clone LTF-2; BioXcell, Lebanon, NH) antibodies were injected intraperitoneally at a concentration of 1mg/mL in a volume of 200uL in pH 7.0 InVivoPure buffer (BioXcell ...
• LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration

  Yalan Deng, et al., bioRxiv - Cell Biology 2023

  Quote: ... or rat IgG2a isotype control (Bio X Cell, BE0089, clone 2A3; RRID: AB_1107769) 6 hours after partial hepatectomy or CCl4 treatment ...
• TRAIL agonists rescue mice from radiation-induced lung injury

  Jillian Strandberg, et al., bioRxiv - Pathology 2023

  Quote: ... or given 100 μg isotype control of polyclonal Armenian hamster IgG (BE0091; BioXcell) via IP injection (n=3/treatment) ...
• Anti-CD47 immunotherapy as a therapeutic strategy for the treatment of breast cancer brain metastasis

  Jessica D. Mackert, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mice were randomized and received IP injections of isotype control (Bioxcell, Cat# BE0089) or anti-CD47 antibody (Bioxcel ...
• IFNγ-dependent remodelling of the myeloid landscape underlies control of IFNγ-insensitive tumours

  Vivian W.C. Lau, et al., bioRxiv - Immunology 2024

  Quote: ... mice were treated with CD8 or NK1.1 depleting antibodies or isotype controls (BioXCell, anti-CD8β Cat ...
• Pathogenic, but not non-pathogenic, Rickettsia evade inflammasome-dependent IL-1 responses to establish an intracytosolic replication niche

  Oliver H. Voss, et al., bioRxiv - Microbiology 2022

  Quote: ... or an isotype control IgG (Armenian hamster IgG) antibody (Ab) were purchased from BioXCell. αCaspase (Casp)-1 Ab was purchased from Adipogen ...
• Altered costimulatory signals and hypoxia support chromatin landscapes limiting the functional potential of exhausted T cells in cancer

  B. Rhodes Ford, et al., bioRxiv - Immunology 2021

  Quote: ... anti-4-1BB (clone 3H3) and isotype controls were obtained from Bio X Cell.
• Macrophage proliferation machinery leads to PDAC progression, but susceptibility to innate immunotherapy

  Chong Zuo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Control mice were treated with the same doses/volumes of IgG (clone HRPN, BioXCell) and PBS liposomes.
• Injectable Liposome-based Supramolecular Hydrogels for the Programmable Release of Multiple Protein Drugs

  Santiago Correa, et al., bioRxiv - Bioengineering 2021

  Quote: ... Mouse IgG1 isotype control antibody (clone MOPC-21) was purchased from Bio X Cell. Tag-free and histidine tagged human IL-12 were both purchased from Sino Biologicals.
• Discovery of A New Class of Integrin Antibodies for Fibrosis

  Ji Zhang, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... Anti-TGFβ neutralizing antibody (1D11) and the isotype control mouse IgG1 were from BioXcell. SB-525334 and bleomycin were from Sigma ...
• PD-1 and CTLA-4 exert additive control of effector regulatory T cells

  Joseph A. Perry, et al., bioRxiv - Immunology 2022

  Quote: ... or isotype control antibodies (clone: 2A3, BioXcell, and clone: polyclonal Armenian hamster IgG, BioXcell). The cells were blocked in 100µl of PD-1/CTLA-4 blocking cocktails in sterile MACS buffer (2% FCS ...
• Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening

  Azucena Ramos, et al., bioRxiv - Cancer Biology 2022

  Quote: ... or 200μg of InVivoMAb mouse IgG2a isotype control antibody (clone C1.18.4, Bio X Cell). For in vivo blocking of NKG2A ...
• Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening

  Azucena Ramos, et al., bioRxiv - Cancer Biology 2022

  Quote: ... or 200μg of InVivoMAb anti-horseradish peroxidase control antibody (clone HRPN, Bio X Cell), starting the day after ACT ...
• Subcutaneous BCG vaccination protects against streptococcal pneumonia via regulating innate immune responses in the lung

  Alisha Kang, et al., bioRxiv - Immunology 2022

  Quote: ... San Fracisco) or 200μg of isotype control mAb (clone 2A3, BioXCell, West Lebanon, NH) at 1 hr post-bacterial challenge ...
• Integration of Avidity and Differentiation is enabled by CD8⁺ T-cell sensing of IFN-γ

  Lion F.K. Uhl, et al., bioRxiv - Immunology 2023

  Quote: ... In some experiments 50 ug of isotype matched control antibody (rat IgG2a, BioXCell, #BE0089) or anti-NK1.1 (BioXCell ...
• Myeloperoxidase promotes a tumorigenic microenvironment in non-small cell lung cancer

  Paulina Valadez-Cosmes, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or with rat IgG2b isotype control antibody (Clone LTF-2, BioxCell; catalog no. BE0090). When tumors became palpable (after about 5 days) ...
• Oncogenic Kras^G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8⁺ T cells dependent manner

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... The control (Isotype/vehicle) mice received a cocktail of Rat IgG2a (BioXcell, clone 2A3), Syrian hamster IgG (BioXcell ...
• Defining the mechanisms of action and resistance to the anti-PD-1+LAG-3 and anti-PD-1+CTLA-4 combinations in melanoma flank and brain models

  Manali S. Phadke, et al., bioRxiv - Immunology 2023

  Quote: ... IgG1 isotype control (200 μg/100 μL; clone HRPN; cat. #BE0088; Bio X Cell) and Syrian hamster IgG (200 μg/100 μL ...
• Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blocker

  Tomás A. Martins, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or InVivoMAb mouse IgG1 isotype control (clone MOPC-21; #BE0083, Bio X Cell, USA) or conditioned-media from 24 h-rested ...
• Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

  Or-Yam Revach, et al., bioRxiv - Cancer Biology 2024

  Quote: ... MDOTS were treated with isotype control IgG2a (Bio X Cell, 2A3, 10 μg/mL), anti-PD-1 (Bio X Cell ...
• PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity

  Florian Wiede, et al., bioRxiv - Cancer Biology 2021

  Quote: ... or rat IgG2a isotype control (100 μg in 200 μl D-PBS, Bio X Cell) every four days for up to 27 days ...
• The hair cycle underlies regulation of Langerhans cell renewal

  Benjamin Voisin, et al., bioRxiv - Immunology 2019

  Quote: ... Hélène Haegel (Transgene SAS, Strasbourg) or rat IgG2a isotype control (2A3, BioXcell, West Lebanon, NH) by sub-cutaneous injections ...
• Cancer cell CCR2 orchestrates suppression of the adaptive immune response

  Miriam R. Fein, et al., bioRxiv - Cancer Biology 2019

  Quote: ... or control rat IgG2b antibody (Clone LTF-2; BE0090; Bio X Cell, West Lebanon, NH) every three days starting from day 0 and until day 30 ...
• Integrin signaling is critical for myeloid-mediated support of T-cell acute lymphoblastic leukemia

  Aram Lyu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... or 3) respective isotype controls (HRPN and LTF-2; all InVivoMAb antibodies are from BioXCell). T-ALL burden was evaluated 24-48 hours after the final injection.
• Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocytes accumulating hepatitis B surface antigen

  Ian Baudi, et al., bioRxiv - Microbiology 2020

  Quote: ... 250µg anti-IFNαβR1 antibody (clone MAR1-5A3) or isotype control (IgG1) (BioXcell, Lebanon, NH, USA) were injected intraperitoneally ...
• Miltefosine enhances infectivity of miltefosine-resistant Leishmania infantum by attenuating innate immune recognition

  Dimitri Bulté, et al., bioRxiv - Microbiology 2021

  Quote: ... Hundred µg of the antibody or an IgG2a isotype control antibody (clone C1.18.4; BioXCell, USA) was given intraperitoneally (i.p. ...
• Combinatorial Immunotherapies Overcome MYC-Driven Immune Evasion

  Joyce V. Lee, et al., bioRxiv - Cancer Biology 2021

  Quote: ... the control group was treated with the respective isotype antibodies (Bio X cell #BE0290, #BE0090). For experiments involving CpG ...
• A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity

  Shuwei Liang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or rat IgG2a isotype control (100 μg in 200 μl D-PBS, Bio X Cell) twice per week ...
• Antigen-presenting type-I conventional dendritic cells facilitate curative checkpoint blockade immunotherapy in pancreatic cancer

  Krishnan K. Mahadevan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Isotype controls for anti-CD11c treated mice were injected with Armenian hamster IgG (BioXcell, BE0260) in the same route ...
• “Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression”

  Marie C. Hasselluhn, et al., bioRxiv - Cancer Biology 2023

  Quote: ... IgG (InVivoMab rat IgG1 isotype control, anti-horseradish peroxidase; Bio X Cell, BE0088; RRID: AB_1107775), α VEGFR2 (InVivoMab anti-mouse VEGFR2 (DC101) ...