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Citations for The Jackson Laboratory :
51 - 78 of 78 citations for SNCA Human since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Neuroscience 2023Quote: We used 5xFAD mice which express five human familial Alzheimer’s disease mutations driven by the mouse Thy1 promoter (Oakley et al., 2006) (The Jackson Laboratory [B6SJL-Tg (APPSwFlLon ...
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bioRxiv - Immunology 2019Quote: ... Plates were washed as above and incubated for 2h with 1:500 dilution of an alkaline phosphatase-conjugated goat F(ab′)2 anti-human IgG (Jackson Laboratories). Plates were washed and developed for 15 min with 100 μl/well of a Sigmafast p-nitrophenyl phosphate solution (Sigma-Aldrich) ...
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bioRxiv - Immunology 2020Quote: ... CAR transduction was measured using anti-CAR antibody Goat F(ab’)2 anti-Human IgG (H+L)-Alexa Fluor 647 (Jackson Laboratories). CD107a degranulation was measured with anti-human CD107a (LAMP-1 ...
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bioRxiv - Physiology 2019Quote: ... B6.Cg-Tg(UBC-cre/ERT2)1Ejb/J Cre- expressing mice driven by the human ubiquitin C (UBC) promoter were bred to mice containing a loxP-flanked STAT3flox/flox sequence (Jackson Laboratories). Double transgenic phenotype (STAT3Δ/Δ ...
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bioRxiv - Neuroscience 2020Quote: Transgenic R6/1 mice (B6-CBA-Tg (HDexon1) 61Gpb/1J) expressing a transgene containing the human HD gene were obtained from Jackson Laboratory (RRID ...
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bioRxiv - Neuroscience 2020Quote: Transgenic hSOD1G93A mice (B6-Cg-Tg (SOD1-G93A) 1Gur/J) carrying a mutant form of the human SOD1 gene were obtained from Jackson Laboratory (RRID ...
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bioRxiv - Neuroscience 2022Quote: ... 16,255 mouse gene symbols were translated into human gene symbols using a reference gene list from Mouse Genome Informatics (The Jackson Laboratory; retrieved from www.informatics.jax.org/downloads/reports/HOM_MouseHumanSequence.rpt on 28.10.2020 ...
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bioRxiv - Neuroscience 2022Quote: ... harboring T34 isoform of microtubule-associated protein tau with one N-terminal insert and four microtubule binding repeats (1N4R) encoding the human P301S mutation were obtained from Jackson Laboratory and maintained in a C57Bl/6j genetic background in standard vivarium environment (12h light:12h dark cycle) ...
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bioRxiv - Neuroscience 2023Quote: ... plates were incubated with anti-mouse IgG or anti-human IgG (1:5000 in 1% BSA; Jackson Laboratory, Bar Harbor, ME) for 1 hour at 37°C ...
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bioRxiv - Cell Biology 2023Quote: ... Low dose busulfan conditioned NBSGW female mice were chosen for the limiting-dilution secondary transplantation since this xenograft model was previously shown to be more sensitive for detection of human cell engraftment than non-conditioned NBSGW mice or sublethally irradiated NSG mice (Jackson Laboratory) 60 ...
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bioRxiv - Cancer Biology 2023Quote: ... mouse NPp53 or human prostate organoids were grafted into 6-8 week old NOD/SCID male mice (NOD.CB17-Prkdcscid/J, Jackson Laboratory 001303). NOD/SCID mice underwent surgical castration at 7 days prior to grafting ...
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bioRxiv - Immunology 2023Quote: ... while the anti-CD40 antibodies were detected using an Alexa Fluor 488-conjugated goat anti-human-F(ab)2 (Jackson Laboratories). Cells were analyzed using a FACSVerse instrument (BD).
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bioRxiv - Microbiology 2023Quote: ... Pellet was resuspended with 100 µL of antibody master mix containing (1:30 dilution of Anti-Human IgA, APC [Miltenyi, Cat#130-113-472], 1:30 dilution mouse serum [Jackson labs, Cat #15000120] ...
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bioRxiv - Cell Biology 2024Quote: ... Specific chaperone classes were annotated by Shemesh et al.43 The human chaperone UniProt codes were converted to mouse using Mouse Genome Informatics homologies (Jackson Laboratory). The feature analysis was handled using an in-house R script established for a recent study.12 Significance was determined using either a Wilcoxon test or a Fischer test ...
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bioRxiv - Neuroscience 2020Quote: In vivo neuronal conversion of human glioblastoma cells was conducted using Rag1 KO immunodeficient mice (B6.129S7-Rag1tm1Mom/J, The Jackson Laboratory, Stock #002216). Half a million (5×105 ...
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bioRxiv - Neuroscience 2019Quote: ... Heterozygous transgene mice were then bred to mouse expressing FLP-1 recombinase gene under the direction of the human ACTB promoter (The Jackson Laboratory #005703), to create a mouse line where the third exon PI31 is flanked by two LoxP sites (PI31fl/fl) ...
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bioRxiv - Systems Biology 2020Quote: ... The mouse-human homology mapping was obtained from the Mouse Genome Informatics (MGI) database hosted by Jackson Laboratories (Blake et al., 2017).
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bioRxiv - Neuroscience 2022Quote: ... that is homozygous floxed for all three Mint genes (fMint 1fMint1; JMint2fMint2; JMint3fMint3) carrying the APPswe/PresenilinlΔexon9 transgene that overproduces human Aβ(Jackson Laboratory stock #004462) (Ho et al. ...
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bioRxiv - Cancer Biology 2023Quote: ... that are knockout for the mouse FcRn heavy chain and express the genomic transgene of the human FcRn heavy chain under the control of the human FcRn promoter were used to study the plasma half-life of mAbs (Jackson laboratories (JAX), USA) ...
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bioRxiv - Cancer Biology 2023Quote: ... 20-weeks-old female NOD.Cg-PrkdcscidIl2rγtm1Wjl/SzJ (NSG) and NOD/ShiLtJ-Prkdcem1AMC Il2rgem1AMC (NSGA) mice engrafted with human CD34+ HSCs were obtained from Jackson Laboratory (ME, USA) and JA BIO (Suwon ...
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bioRxiv - Genomics 2019Quote: ... genes that had no expert curated 1:1 orthologs between mouse and human (Mouse Genome Informatics, The Jackson laboratory, version 11/22/2016). Gene expression was then scaled to a total of 1M UMIs (or transcript per million (TPM) ...
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bioRxiv - Cell Biology 2020Quote: ... and transgenic mice that express Cre recombinase under control of the human bestrophin-1 (BEST1) promoter (C57BL/6-Tg(BEST1-cre)1Jdun/J) (Iacovelli et al, 2011) were purchased from Jackson lab (Bar Harbor, ME). CD-1 IGS mice were purchased from Charles River (Wilmington ...
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bioRxiv - Cancer Biology 2021Quote: ... A knock-in mouse line that conditionally expresses Dnmt3aR878H allele (equivalent to DNMT3AR882H in humans) from the endogenous locus (Jackson Laboratory stock No. 031514) was described13 ...
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bioRxiv - Physiology 2020Quote: ... we crossed P2Y6R-floxed mice with mice expressing recombinase under the control of human skeletal actin promoter (HSA-Cre 79; Jackson Laboratories (Stock No. 006149); genetic background ...
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bioRxiv - Immunology 2024Quote: ... the cells were washed twice with FACS buffer and stained with Alexa Fluor 488-conjugated goat-anti human IgG Fc antibody (Jackson Laboratory, 109-545-098). The binding of mouse anti-human CD3 (clone ...
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bioRxiv - Neuroscience 2023Quote: ... The membrane was washed by TBS and then incubated with secondary antibodies (anti-mouse IgG, anti-rat IgG, anti-human IgG, Jackson Laboratory, Bar Harbor, ME; 1:5000) diluted by 1% milk in TBS for 1h at room temperature ...
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bioRxiv - Neuroscience 2023Quote: ... familial AD (FAD) mutations and human Presenilin1 (PS1) with the M146L and L286V FAD mutations [18] were purchased from Jackson Labs (Bar Harbor, ME; JAX#34840) and were maintained on a mixed B6/SJL genetic background as described [19] ...
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bioRxiv - Neuroscience 2021Quote: ... and London: V717I) and two mutations in human PSEN1 (M146L and L286V) (Oakley et al., 2006) were obtained from Jackson Labs (JAX MMRRC Stock No: 34848-JAX). These mice were used to establish an in-house breeding colony in which 5xFAD mice were bred to fully congenic WT C57Bl/6J mice obtained from Jackson labs (Jax Stock Number ...