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Citations for The Jackson Laboratory :
1551 - 1600 of 1858 citations for 5 Pyrimidinecarbonitrile 2 4 diamino 6 methoxy 9CI since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Immunology 2020Quote: ... iNOS2 deficient mice (B6.129P2-Nos2tm1Lau/J #002609) were obtained from Jackson laboratories (Fig. 5). Female mice were used during Mtb infection due to extended duration of co-housing ...
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bioRxiv - Genetics 2022Quote: ... Cells were incubated with 5% normal donkey serum (017-000-121, Jackson Laboratory, USA) in PBST for 30 min at room temperature (RT ...
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bioRxiv - Neuroscience 2023Quote: ... Cuticle filets were blocked in 5% normal donkey serum (Jackson Laboratories, West Grove, PA) for at least 30 minutes at room temperature followed by incubation with respective primary antibodies ...
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bioRxiv - Immunology 2023Quote: The following 5-7 weeks old male or female mice were from Jackson Laboratories, Inc. ...
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bioRxiv - Cell Biology 2020Quote: ... and transgenic mice that express Cre recombinase under control of the human bestrophin-1 (BEST1) promoter (C57BL/6-Tg(BEST1-cre)1Jdun/J) (Iacovelli et al, 2011) were purchased from Jackson lab (Bar Harbor, ME). CD-1 IGS mice were purchased from Charles River (Wilmington ...
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bioRxiv - Genetics 2021Quote: Catalytic deficient heterozygous PKD2S707A/S711A/WT -knock-in (PKD2SSAA/WT-KI) mice on a C57BL/6 background were obtained from Jackson Laboratory (Bar Harbor, ME). Male PKD2 wild-type mice and PKD2SSAA/WT-KI mice of 6 wks old (body weigh ∼20 g ...
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bioRxiv - Microbiology 2022Quote: Six- to eight-week-old male C57BL/6 Nos2-/- (Stock No. 002609) and C3HeB/FeJ (Stock No. 000658) mice (Jackson Laboratory, Bar Harbor, Maine) were used for intra-cerebroventricular (i.c.vent. ...
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bioRxiv - Cell Biology 2022Quote: ... Korea) with Alb-Cre C57BL/6 mice containing the Cre recombinase sequence driven by the albumin promoter (The Jackson Laboratory, Bar Harbor, ME, USA). Prom1 lineage tracing mice were generated by crossing Prom1Cre/ERT2-nlacZ C57BL/6 mice with Rosa26tdTomato C57BL/6 mice containing the tdTomato sequence prevented by the loxP- flanked STOP cassette (Stock No ...
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bioRxiv - Immunology 2021Quote: ... C57BL/6 and hemizygous K18-hACE C57BL/6J mice (strain: 2B6.Cg-Tg(K18-ACE2)2Prlmn/J) were purchased from Jackson Laboratory (Bar Harbor, ME) and housed at OSU within an AALAC-accredited facility (University Laboratory Animal Resources ...
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CD8+ T-cell-mediated immunoediting influences genomic evolution and immune evasion in murine gliomasbioRxiv - Cancer Biology 2019Quote: PDGF+PTEN-/- gliomas were generated by intracranial injection of a PDGF-IRES-Cre retrovirus into the subcortical white matter of adult mice with the Ptenlox/lox genotype (C57BL/6 background, Jackson Lab Stock No: 006440). Gliomas generated in hosts with intact immunity can graft and grow in syngeneic immune-competent recipients ...
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bioRxiv - Cancer Biology 2021Quote: ... 6.0e6 cells were resuspended in 2:1 vol/vol matrigel:media and subcutaneously implanted into the left and right fat pads of 6-to-8-week old female NSG (NOD-scidl IL2Rgnull) mice (Jackson Laboratory stock no. 005557). When either tumor was ~100-200 mm3 mice were randomized to tamoxifen or vehicle treatment ...
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bioRxiv - Neuroscience 2021Quote: ... The transgenic mouse lines employed were all on a C57BL/6 genetic background bred in-house from the following founders: CRH-IRES-Cre+/+ (Jax #: 012704; Jackson Laboratory, Bar Harbor, ME), tdTomato+/+ (stop-floxed ...
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bioRxiv - Cancer Biology 2020Quote: Wild-type C57BL/6J and green-fluorescent protein (GFP) expressing mice [C57BL/6-132Tg (UBC-GFP) 30Scha/J] were obtained from Jackson Laboratory (Bar Harbor, ME). Mice were bred and maintained in the Center for Comparative Medicine at the University of Colorado Denver ...
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bioRxiv - Neuroscience 2022Quote: ... Transgenic mice expressing YFP under the control of the Thy-1 promoter (Thy1-YFP-16) on a C57BL/6 background were acquired from Jackson Laboratories (Bar Harbor, ME). The original Thy1-YFP-16 mice (IMSR Cat# JAX:003709 ...
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bioRxiv - Cancer Biology 2022Quote: ... FLC PDX tumor cells were implanted subcutaneously into the rear flank of 6-to 8-week-old female NOD-SCID mice (Jackson Laboratory, Bar Harbor, ME) and allowed to grow to 150 mm3 for efficacy studies or 500 mm3 for pharmacokinetic/pharmacodynamic studies ...
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bioRxiv - Microbiology 2021Quote: ... Alb-Cre Transgenic mice (C57BL/6-Tg [Alb-Cre] 21Mgn/J) using albumin promoter to express Cre recombinase were obtained from Jackson Laboratory (Bar Harbor, ME). For Ad-GFP/rcccDNA transduction ...
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bioRxiv - Bioengineering 2020Quote: ... was orthotopically injected into the inguinal mammary fat pad of female NU/J mice (6−8 weeks old, The Jackson Laboratory, Stock No: 002019). At day 7 post transplantation ...
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bioRxiv - Neuroscience 2022Quote: ... transgenic mice expressing Thy-1 GCaMP6s (8-14 weeks old, male/female, background strain C57BL/6, purchased from the Jackson Laboratory, Bar Harbor, USA) were used ...
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bioRxiv - Immunology 2022Quote: ... Thomas Moran (Icahn School of Medicine at Mount Sinai)[14] and were used with sex and age matched C57BL/6 mice (Jackson Laboratory bred in house). Mavs-/- mice (B6;129-Mavstm1Zjc/J ...
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bioRxiv - Molecular Biology 2019Quote: ... Embryonic pups (7-9/litter) were removed by caesarean section from a timed-pregnant female C57BL/6 mouse per time point (The Jackson Laboratory, Bar Harbor, ME) and euthanized ...
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bioRxiv - Developmental Biology 2020Quote: ... The Ddx4-Cre (Vasa-Cre) mouse line was maintained on a mixed genetic background (129/C57BL/6×FVB/N) (cat. #J006954, Jackson Laboratory, Bar Harbor, ME). The Tg(Gdf9-iCre)5092Coo mouse line was maintained on the C57BL/6J genetic background (cat ...
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bioRxiv - Immunology 2019Quote: ... animals were purchased and crossed to MHC-I deficient C57BL/6 mice for no less than three generations to remove endogenous MHC-I molecules (The Jackson Laboratory, Bar Harbor, ME). Crossing these Cre-recombinase expressing mice with the Db LoxP transgenic animals described above resulted in cKO of H-2Db ...
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bioRxiv - Microbiology 2021Quote: ... and inbred C57BL6 Rag1 Knockout (KO, lacking mature T- and B-cells, male and female)) mice (6-8 weeks) were purchased from Jackson Laboratory (Bar Harbor ME). All experiments were conducted in the animal biosafety level 3 (ABSL-3 ...
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bioRxiv - Cancer Biology 2020Quote: ... transgenic C57BL/6 mice expressing enhanced-GFP under the regulation of the ubiquitin promoter were used (B6-EGFP, The Jackson Laboratory, Bar Harbor, ME). The Animal Care and Use Committees of the Technion (Haifa ...
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bioRxiv - Microbiology 2021Quote: Bone marrow derived macrophages (BMDMs) were isolated from the tibias and femurs of 6-8 week old C57BL/6J (Jackson Laboratories stock no. 000664) mice ...
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bioRxiv - Immunology 2020Quote: ... CD73−/− mice on C57BL/6 background (Thompson et al., 2004) and B6N.129P-Adora1tm1Bbf/J mice were purchased from Jackson Laboratories (Bar Harbor, ME), bred at our facility and genotyped as previously described (Johansson et al. ...
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bioRxiv - Bioengineering 2019Quote: ... a permanent cortical photothrombotic stroke was induced on young adult C57BL/6 male mice (8–12 weeks) obtained from Jackson laboratories (Bar Harbor, ME). The mice were anesthetized with 5% isoflurane and placed in a stereotactic setup ...
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bioRxiv - Physiology 2020Quote: ... Arid1a conditional knockout mice were generated in the C57BL/6 background by crossing Pgrcre/+(27) or LtfiCre/+ (28) (The Jackson Laboratory Stock No: 026030) males with Arid1af/f (29 ...
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bioRxiv - Immunology 2020Quote: ... 16-week-old (young) and 91-week-old (aged) female C57BL/6 mice (n=10 per group) were purchased from Jackson Laboratory (Bar Harbor, Maine). A porous titanium (Ti6Al4V ...
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bioRxiv - Developmental Biology 2020Quote: ... Wild type CD1 mice were purchased from Charles Rivers (strain code 022) and wild type C57Bl/6 mice were purchased from Jackson Laboratories (stock no 000664). The R26R strain (Gt(ROSA)26Sortm1Sor stock#0033O9 from Jackson’s Lab ...
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bioRxiv - Neuroscience 2020Quote: Adult (age 8-16 weeks) CD1 mice or C57BL/6-Tg(CAG-EGFP)10sb/J mice that express GFP ubiquitously (Jackson Laboratories, Bar Harbor, ME) of both sexes were used ...
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bioRxiv - Cell Biology 2022Quote: ... We generated mice with Adipoq+ cell specific deletion of Csf1 by crossing Csf1flox/flox mice with the mice with an Adipoq promoter-driven Cre transgene on the C57BL/6 background (AdipoQ-Cre: The Jackson Laboratory, stock No: 028020). We also generated AdipoQ-mTmG reporter mice by crossing the mTmG mice (The Jackson Laboratory ...
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bioRxiv - Pathology 2022Quote: C57BL6 (WT) and C57BL/6-Tg(Vav1-NUP98/HOXD13)G2Apla/J (NHD13) mice [29] were originally purchased from Jackson Laboratories (Bar Harbor, ME, USA). For simplicity ...
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bioRxiv - Neuroscience 2023Quote: Experiments were performed on male wild type and Mecp2tm1-1Bird mice (Guy et al., 2001) C57BL/6 genetic background (Jackson Laboratory, stock number 003890). Hemizygous mutant males (hereafter referred as to Mepc2−/y mice ...
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bioRxiv - Neuroscience 2024Quote: ... Male and female mice (Mus musculus) were bred on a C57BL/6 background at the Harvard Center for Comparative Medicine or obtained from Jackson Laboratories (Bar Harbor, ME). Mice were housed in groups of up to five animals and maintained on a 12hr light/dark cycle ...
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bioRxiv - Immunology 2024Quote: ... and old (18-22 months) C57BL/6 (B6) male mice were obtained from the National Institute on Aging colony or from Jackson Laboratories (Bar Harbor, ME). A2BR-/- mice on a B6 background (B6.129P2-Adora2btm1Till/J ...
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bioRxiv - Neuroscience 2023Quote: ... All animals used for this study were 6-8 week old male and female C57/BL6 mice purchased from Jackson Labs (Bar Harbor, Maine).
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bioRxiv - Microbiology 2023Quote: ... and Cybb-/- (41) mice from the C57BL/6 lineage were bred and maintained at the University of Michigan or directly purchased (Jackson Laboratory, Bar Harbor, ME). In each model of bacteremia ...
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bioRxiv - Cancer Biology 2023Quote: Female BALB/c (JAX# 002019) or C57BL/6 mice (JAX #000664) aged 8 to 10 weeks were purchased from Jackson Laboratories (Bar Harbor, ME). All animal studies were performed in accordance with Duke Institutional Animal Care and Use Committee (IACUC ...
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bioRxiv - Cell Biology 2023Quote: Cre driver mice used in this study included the Zp3-Cre line C57BL/6-Tg(Zp3- cre)93Knw/J (Jackson Laboratories stock #003651(53)) ...
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bioRxiv - Microbiology 2023Quote: ... Two replicate trials were conducted using male and female IL-10-KO mice (Mus musculus) on a C57BL/6 background (B6.129P2-Il10tm1Cgn/J, strain 2251; Jackson Laboratories, Bar Harbor, Maine, U.S.). IL-10-KO mice are a well-demonstrated model for Crohn’s research and the C57BL/6 genetic line shows some genetic-based resistance to developing symptoms (61) ...
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bioRxiv - Immunology 2023Quote: ... PAR2 knockout mice (PARKO) based on a C57BL/6 background were purchased from the Jackson Laboratory (B6.Cg-F2rl1tm1Mslb/J mice; The Jackson Laboratory, Bar Harbor, ME). Controls were age- and sex-matched wild-type C57B6 mice also purchased from The Jackson Laboratory.
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bioRxiv - Systems Biology 2023Quote: Animal Research (involving vertebrate animals, embryos or tissues) Male C57BL/6 mice 8 weeks of age were purchased from Jackson Laboratory (Bar Harbor, ME). All animals were housed in accordance with guidelines from the American Association for Laboratory Animal Care and Research protocols and approved by the Institutional Animal Care Use Committee at Virginia Commonwealth University (Protocol No ...
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bioRxiv - Cancer Biology 2023Quote: The TR.1 cell line was propagated as orthotopic tumors in the left lung lobe of nine-week-old C57BL/6 mice (WT; C57BL/6J; #000664, Jackson Laboratory, Bar Harbor ME). Cells were prepared in a solution of 1.35 mg/mL Matrigel (Corning #354234 ...
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bioRxiv - Immunology 2023Quote: ... Itk-/-and ITKas IL17-GFP/Foxp3-RFP dual reporter strains were generated by crossing IL17-GFP (B-IL17A-EGFPtm1, Biocytogen, Worchester, MA) with Foxp3-RFP (C57BL/6-Foxp3tm1Flv/J, Jackson Laboratory, Bar Harbor, ME) strain (24 ...
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bioRxiv - Neuroscience 2023Quote: ... Experiments involving optogenetic manipulation of thalamic inhibitory circuits were conducted in double-transgenic mice generated by mating homozygous Ai32 mice carrying a floxed ChR2-EYFP fusion gene inserted in the Gt(ROSA)26Sor locus in a C57BL/6 strain (Jackson Laboratory; stock no. 012569) or homozygous Ai40 mice carrying a floxed ArchT-EYFP fusion gene inserted in the Gt(ROSA)26Sor locus in a C57BL/6 strain (Jackson Laboratory ...
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bioRxiv - Neuroscience 2023Quote: ... Hindpaw anatomical localization of Pacinian corpuscle experiments were conducted in double-transgenic mice generated by mating homozygote Ai14 males carrying a floxed tdTomato fusion gene inserted in the Gt(ROSA)26Sor locus in a C57BL/6 strain 38 (Jackson Laboratory; stock no. 007914) with heterozygote ER81/Etv1-CreER females expressing the CreERT2 fusion protein from the ER81/Etv1 promoter elements 39 (Jackson Laboratory ...
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bioRxiv - Neuroscience 2023Quote: ... or homozygous Ai40 mice carrying a floxed ArchT-EYFP fusion gene inserted in the Gt(ROSA)26Sor locus in a C57BL/6 strain (Jackson Laboratory; stock no. 021188) with homozygous PV-Cre (Jackson laboratory ...
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Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosisbioRxiv - Molecular Biology 2024Quote: ... Tamoxifen-inducible adipocyte-specific Six1 knock-out mice (iAdipo-Six1-/-) were generated by cross breeding C57BL/6-Tg(Adipoq-cre/ERT2)1Soff/J (iAdipoCre) (Jackson Labs; Cat No. 025124) and Six1loxP/loxP mice ...
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bioRxiv - Genomics 2020Quote: ... male and female C57BL/6J mice (3-4 months old animals) were obtained from Jackson Laboratories. Both Charles Rivers and Jackson Laboratories have specific-pathogen-free (SPF ...