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9001 - 9050 of 10000+ citations since 2019

• Gain-of-function assay for SARS-CoV-2 M^pro inhibition in living cells

  Seyad Arad Moghadasi, et al., bioRxiv - Microbiology 2020

  Quote: ... or goat anti-rabbit IgG-HRP (1:10,000 Jackson Labs # 111-035-144). HRP secondary antibody was visualized using the SuperSignal West Femto Maximum Sensitivity Substrate (Thermo Fisher # PI34095) ...
• A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

  Michael Alexanian, et al., bioRxiv - Molecular Biology 2020

  Quote: A Tcf21MCM37 mouse was crossed with a Rosa26-Ai6 mouse (Jackson Laboratory stock# 007906). At 10 weeks of age ...
• FER-mediated tyrosine phosphorylation and PIK3R2/p85β recruitment on IRS4 promotes the PI3K-AKT signaling pathway and tumorigenesis in ovarian cancer

  Yanchun Zhang, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Proteins were detected with horseradish peroxidase (HRP)-conjugated secondary antibodies (Jackson Laboratory) and ECL (Pierce).
• Erythropoietin regulates transcription and YY1 dynamics in a pre-established chromatin architecture

  Andrea A. Perreault, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Female BALB/cJ mice (12 weeks old, Jackson Laboratories) were infected via intraperitoneal injection of ~104 spleen focus-forming units of Anemia-inducing strain of the Friend virus (FVA) ...
• Ontogeny and function of the circadian clock in intestinal organoids

  Andrew E. Rosselot, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Immune-deficient NSG mice (Jackson Laboratories) were utilized for kidney capsule transplantation of HIOs5 ...
• Ontogeny and function of the circadian clock in intestinal organoids

  Andrew E. Rosselot, et al., bioRxiv - Molecular Biology 2020

  Quote: Mouse enteroids were established and cultured from 3-6 month old C57BL/6J (Jackson Laboratories), PER2::LUCIFERASE72 and Bmal1f/f-EsrCRE49 ...
• Cystin gene mutations cause autosomal recessive polycystic kidney disease associated with altered Myc expression

  Chaozhe Yang, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Ksp-Cre mice were obtained from Jackson Laboratory (Bar Harbor, ME). Mouse colonies were maintained in the animal facility at Children’s National Research Institute.
• A Novel Surgical Method for Continuous Intra-Portal Infusion of Gut Microbial Metabolites in Mice

  Danny Orabi, et al., bioRxiv - Microbiology 2020

  Quote: 8-10 week male and female C57BL/6J mice were purchased from Jackson Laboratory and housed under specific pathogen–free conditions at the Biological Resources Unit within the Cleveland Clinic Lerner Research Institute ...
• Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer’s-related mice

  Mickael Audrain, et al., bioRxiv - Neuroscience 2020

  Quote: ... APPKM670/671NL/PSEN1∆exon9 (APP/PSEN1) and MAPTP301S (PS19) mice were obtained from Jackson Laboratories. Tyrobp knockout (Tyrobp−/− ...
• Rescuing auditory temporal processing with a novel augmented acoustic environment in a mouse model of congenital SNHL

  Adam C. Dziorny, et al., bioRxiv - Neuroscience 2020

  Quote: ... Founder breeding pairs (JAX 000671) were obtained from Jackson Labs (Bar Harbor, ME) and our colony was maintained in micro-isolator facilities in the institutional vivarium ...
• Dicer1 promotes Aβ clearance via blocking B2 RNA-mediated repression of apolipoprotein E

  Yan Wang, Meiling Lian, Liping Song, Shengzhou Wu, bioRxiv - Neuroscience 2020

  Quote: ... APPswe/PSEN1dE9(APP/PS1) mice(Jackson Laboratory, stock number 004462) were multiplied and genotyped according to the guidance by Jackson Laboratory ...
• Dicer1 promotes Aβ clearance via blocking B2 RNA-mediated repression of apolipoprotein E

  Yan Wang, Meiling Lian, Liping Song, Shengzhou Wu, bioRxiv - Neuroscience 2020

  Quote: ... were multiplied and genotyped according to the guidance by Jackson Laboratory. Both genders of transgenic mice were used and WT littermates were used as control mice ...
• Partial Inhibition of Mitochondrial Complex I Reduces Tau Pathology and Improves Energy Homeostasis and Synaptic Function in 3xTg-AD Male and Female Mice

  Andrea Stojakovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... triple transgenic 3xTg-AD (B6;129-Tg(APPSwe,tauP301L)1Lfa Psen1tm1Mpm/Mmjax) [50] and their appropriate controls B6129SF2/J (F2) (Stock No: 101045, The Jackson laboratory). Genotypes were determined by PCR as described in [52] ...
• Emergence of Non-Canonical Parvalbumin-Containing Interneurons in Hippocampus of a Murine Model of Type I Lissencephaly

  Tyler G. Ekins, et al., bioRxiv - Neuroscience 2020

  Quote: ... LIS1+/− mice were crossed to PV-Cre (Jackson Labs stock no ...
• Emergence of Non-Canonical Parvalbumin-Containing Interneurons in Hippocampus of a Murine Model of Type I Lissencephaly

  Tyler G. Ekins, et al., bioRxiv - Neuroscience 2020

  Quote: ... Lis1+/−:PV-Cre mice were crossed to Sun1-GFP mice (Jackson Labs stock no. 030952, B6.129-Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat /MmbeJ).
• Emergence of Non-Canonical Parvalbumin-Containing Interneurons in Hippocampus of a Murine Model of Type I Lissencephaly

  Tyler G. Ekins, et al., bioRxiv - Neuroscience 2020

  Quote: ... we crossed LIS1+/fl mice to Nkx2.1-Cre (Jackson Labs stock no ...
• Emergence of Non-Canonical Parvalbumin-Containing Interneurons in Hippocampus of a Murine Model of Type I Lissencephaly

  Tyler G. Ekins, et al., bioRxiv - Neuroscience 2020

  Quote: ... C57BL/6J-Tg(Nkx2-1-cre)2Sand/J) and Emx1-Cre (Jackson Labs stock no. 005628, B6.129S2-Emx1tm1(cre)Krj/J ...
• Emergence of Non-Canonical Parvalbumin-Containing Interneurons in Hippocampus of a Murine Model of Type I Lissencephaly

  Tyler G. Ekins, et al., bioRxiv - Neuroscience 2020

  Quote: ... These mice were bred to wild-type C57BL/6J mice (Jackson Labs stock no. 00064) to maintain global LIS1+/− colonies ...
• Emergence of Non-Canonical Parvalbumin-Containing Interneurons in Hippocampus of a Murine Model of Type I Lissencephaly

  Tyler G. Ekins, et al., bioRxiv - Neuroscience 2020

  Quote: ... LIS1fl/+:Nkx2.1Cre and Lis1fl/+::Emx1Cre lines were crossed to Cre-independent PV-TdTom mice (Jackson Labs stock no ...
• Offline Memory Reactivation Promotes the Consolidation Of Spatially Unbiased Long-Term Cognitive Maps

  Andres D. Grosmark, et al., bioRxiv - Neuroscience 2020

  Quote: ... Imaging experiments were performed in 10 transgenic CaMKIIα-Cre mice on a C57/B16 background (R4Ag11 line, n = 4, Jackson Laboratory, Stock No: 027400, and R1Ag5 line, n = 6, Jackson Laboratory, Stock No ...
• Offline Memory Reactivation Promotes the Consolidation Of Spatially Unbiased Long-Term Cognitive Maps

  Andres D. Grosmark, et al., bioRxiv - Neuroscience 2020

  Quote: ... Imaging experiments were performed in 10 transgenic CaMKIIα-Cre mice on a C57/B16 background (R4Ag11 line, n = 4, Jackson Laboratory, Stock No ...
• Distinct temporal difference error signals in dopamine axons in three regions of the striatum in a decision-making task

  Iku Tsutsui-Kimura, et al., bioRxiv - Neuroscience 2020

  Quote: ... All mice were backcrossed with C57BL/6J (Jackson Laboratory). Animals were housed on a 12 hour dark/12 hour light cycle (dark from 07:00 to 19:00 ...
• Single-cell profiling of histone modifications in the mouse brain

  Marek Bartosovic, et al., bioRxiv - Neuroscience 2020

  Quote: ... on a C57BL/6j genetic background with RCE:loxP (EGFP) animals8 (The Jackson Laboratory mouse strain 32037-JAX) on a C57BL/6xCD1 mixed genetic background ...
• Single-cell profiling of histone modifications in the mouse brain

  Marek Bartosovic, et al., bioRxiv - Neuroscience 2020

  Quote: The mouse line used in this study was generated by crossing Sox10:Cre animals7 (The Jackson Laboratory mouse strain 025807) on a C57BL/6j genetic background with RCE:loxP (EGFP ...
• An evolutionarily conserved Lhx2-Ldb1 interaction regulates the acquisition of hippocampal cell fate and regional identity

  Veena Kinare, et al., bioRxiv - Neuroscience 2020

  Quote: ... The Emx1Cre line was from Jackson Laboratories (strain name: B6.Cg-Emx1tm1(cre)Krj/J ...
• Transcription factor-based gene therapy to treat glioblastoma through direct neuronal conversion

  Xin Wang, et al., bioRxiv - Neuroscience 2020

  Quote: In vivo neuronal conversion of human glioblastoma cells was conducted using Rag1 KO immunodeficient mice (B6.129S7-Rag1tm1Mom/J, The Jackson Laboratory, Stock #002216). Half a million (5×105 ...
• Sex-specific calibration of memory recall by glucocorticoid receptors on cortical astrocytes

  WW Taylor, BR Imhoff, ZS Sathi, KM Garza, BG Dias, bioRxiv - Neuroscience 2020

  Quote: Nr3c1-floxed (GR-floxed) animals were obtained from Jackson Laboratories (Strain #: 012914) and then back-crossed to a C57BL/6J background ...
• Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain

  Nicole J. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: ... Antxr2fl/fl mice in which the transmembrane domain of Antxr2 is flanked by loxP sites were obtained from Jackson Laboratory (#027703), originally donated by Stephen Leppla (NIH ...
• Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain

  Nicole J. Yang, et al., bioRxiv - Neuroscience 2020

  Quote: ... C57BL/6J mice were purchased from Jackson Laboratory (Bar Harbor, ME) and bred at Harvard Medical School ...
• The fragile X mental retardation protein promotes adjustments in cocaine self-administration that preserve reinforcement level

  Jessica L. Huebschman, et al., bioRxiv - Neuroscience 2020

  Quote: WT and Fmr1 KO littermates were produced at the Texas A&M University Health Science Center by Fmr1−/y and Fmr1−/+ breeders (Jackson Laboratory, Stock # 003025) that have been maintained on a C57BL/6N (Charles River ...
• Endothelial CXCL12 regulates neovascularization during tissue repair and tumor progression

  Zeshaan N. Maan, et al., bioRxiv - Molecular Biology 2020

  Quote: All transgenic strains had been backcrossed at least ten generations onto a C57BL/6 background (Jackson Laboratories, Bar Harbor, ME). Rosa–creER ...
• Endothelial CXCL12 regulates neovascularization during tissue repair and tumor progression

  Zeshaan N. Maan, et al., bioRxiv - Molecular Biology 2020

  Quote: ... GFP positive C57BL/6-Tg(CAG-EGFP)1Osb/J mice were similarly obtained from Jackson Laboratory. Mice were maintained under standard pathogen-free conditions according to methods approved by the Stanford University Administrative Panel on Laboratory Animal Care (APLAC) ...
• Regulated control of gene therapies with a drug induced switch

  Alex Mas Monteys, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Five to six-week-old male C57Bl6/j mice were obtained from Jackson Laboratories (Bar Harbor, ME, USA). AAV vectors (AAV9 ...
• Localized Chemogenetic Silencing of Inhibitory Neurons: A novel Mouse Model of Focal Cortical Seizures

  Adi Miriam Goldenberg, et al., bioRxiv - Neuroscience 2020

  Quote: ... We used 6-11 weeks old heterozygous Gad2-IRES-Cre mice (Jax #010802, The Jackson Laboratory, Bar Harbor, ME, USA) of either sex ...
• A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β-cells

  Mark Li, et al., bioRxiv - Molecular Biology 2020

  Quote: ... C57BL/6J mice (The Jackson Laboratory, 000664) were kept on a 12 hr light/dark cycle ...
• Litter expansion alters metabolic homeostasis in a sexually divergent manner

  Kavitha Kurup, et al., bioRxiv - Molecular Biology 2020

  Quote: Litter expansion of male and female C57BL/6J mice was performed by Jackson laboratory (Bar Harbor, ME) and 5 litter sizes (LS ...
• Direct RNA sequencing reveals m⁶A modifications on adenovirus RNA are necessary for efficient splicing

  Alexander M. Price, et al., bioRxiv - Molecular Biology 2020

  Quote: ... incubated with HRP-conjugated secondary (Jackson Laboratories) for 1 h and washed an additional three times in TBST ...
• Cocaine-dependent acquisition of locomotor sensitization and conditioned place preference requires D1 dopaminergic signaling through a cyclic AMP, NCS-Rapgef2, ERK and Egr-1/Zif268 pathway

  Sunny Zhihong Jiang, et al., bioRxiv - Neuroscience 2020

  Quote: ... The transgenic Drd1a-tdTomato BAC mouse (The Jackson Laboratory, #016204), expressing tdTomato selectively in D1-dopaminoceptive neurons (Shuen et al. ...
• Telomere length and oxidative stress variations in a murine model of Alzheimer’s disease progression

  Katia Martínez-González, et al., bioRxiv - Neuroscience 2020

  Quote: ... Mice were purchased from Jackson Laboratories and housed in the Bioterio de la Coordinación de Investigación en Salud ...
• Severe and multifaceted systemic immunosuppression caused by experimental cancers of the central nervous system requires release of non-steroid soluble mediators

  K Ayasoufi, et al., bioRxiv - Immunology 2020

  Quote: ... Adrenalectomized mice were purchased from Jackson Laboratory (Bar Harbor, Maine). These mice were maintained on 1% saline in drinking water for the duration of the experiments ...
• Astrocytes are necessary for blood-brain barrier maintenance in the adult mouse brain

  Benjamin P. Heithoff, et al., bioRxiv - Neuroscience 2020

  Quote: ... were crossed with Tg(Slc1a3-cre/ERT)1Nat (Nathans, 2010) (Jackson Labs stock #012586). We will refer to Gt(ROSA)26Sortm1(DTA)Jpmb/J mice expressing one diphtheria toxin A (DTA ...
• Severe and multifaceted systemic immunosuppression caused by experimental cancers of the central nervous system requires release of non-steroid soluble mediators

  K Ayasoufi, et al., bioRxiv - Immunology 2020

  Quote: ... and MHCII-/- (B6-12952-H2d1Ab1-EA/J) mice were purchased from Jackson Laboratory (Bar Harbor, Maine). Catalog numbers are 000664 ...
• Cytotoxic lymphocytes use mechanosurveillance to target biophysical vulnerabilities in cancer

  Maria Tello-Lafoz, et al., bioRxiv - Immunology 2020

  Quote: 2 × 105 B16F10 or E0771 cells were injected into the tail vein of 4-6 week old C57BL/6J mice (Jackson Labs, 000664). Doxycycline was included in the mouse food (2500 mg/kg ...
• Transient coupling between subplate and subgranular layers to L1 neurons before and during the critical period

  Xiangying Meng, et al., bioRxiv - Neuroscience 2020

  Quote: Mice (C57/Bl6, Jackson Labs; P6-P32) were deeply anesthetized with isofluorane (Halocarbon) ...
• Dynamin-related Irgm proteins modulate LPS-induced caspase-4 activation and septic shock

  Ryan Finethy, et al., bioRxiv - Immunology 2020

  Quote: WT (C57BL/6J) mice were originally purchased from Jackson Laboratories. Irgm1-/- ...
• Thymic rejuvenation via induced thymic epithelial cells (iTECs) from FOXN1-overexpressing fibroblasts to counteract inflammaging

  Jiyoung Oh, et al., bioRxiv - Immunology 2020

  Quote: ... and Rag-/- (Rag1 gene knockout) mice (Jackson Lab #002216). Mouse ages are indicated in each figure legend ...
• Thymic rejuvenation via induced thymic epithelial cells (iTECs) from FOXN1-overexpressing fibroblasts to counteract inflammaging

  Jiyoung Oh, et al., bioRxiv - Immunology 2020

  Quote: ... Other genetically engineered mouse colonies were RIP-mOVA [the rat insulin promoter (RIP)-driven membrane-bound ovalbumin] Tg mice (Jackson Lab #005431); OT-II+ TCR-Tg (transgenic TCR recognizing ovalbumin in the context of MHC-class II ...
• Thymic rejuvenation via induced thymic epithelial cells (iTECs) from FOXN1-overexpressing fibroblasts to counteract inflammaging

  Jiyoung Oh, et al., bioRxiv - Immunology 2020

  Quote: ... OT-II+ TCR-Tg (transgenic TCR recognizing ovalbumin in the context of MHC-class II, I-Ab) mice (Jackson Lab #004194); and Rag-/- (Rag1 gene knockout ...
• Thymic rejuvenation via induced thymic epithelial cells (iTECs) from FOXN1-overexpressing fibroblasts to counteract inflammaging

  Jiyoung Oh, et al., bioRxiv - Immunology 2020

  Quote: ... or FoxN1-Cre mice (Jackson Lab #018448) for the generation of FTg:R26CreERT [tamoxifen (TM)-inducible exogenous FoxN1 overexpression in the R26-expressing tissues] and FTg:FoxN1Cre [exogenous FoxN1 overexpression induced by endogenous FoxN1 promoter-driven Cre-Tg (Gordon et al ...
• Molecular determinants and heterogeneity of tissue-resident memory CD8⁺ T lymphocytes revealed by single-cell RNA sequencing

  Nadia S. Kurd, et al., bioRxiv - Immunology 2020

  Quote: ... both maintained on a C57BL6/J background) mice were bred at UCSD or purchased from Jackson Laboratories. Ddx5fl/fl mice were obtained from Dr ...