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• Active Translation Control of CD4 T Cell Activation by Regulatory T Cells

  Lomon So, et al., bioRxiv - Immunology 2022

  Quote: ... Foxp3YFP-Cre mice (B6.129(Cg)-Foxp3tm4(YFP/icre)Ayr/J: Stock#016959 from Jackson Labs) that have been crossed to B6 Cd45.1 mice (B6.SJL-PtprcaPepcb/BoyJ ...
• Interphotoreceptor matrix proteoglycans IMPG1 and IMPG2 proteolyze in the SEA domain and reveal localization mutual dependency

  Benjamin Mitchell, et al., bioRxiv - Molecular Biology 2022

  Quote: ... were purchased from Jackson Laboratory (stock no: 001433). All mouse populations were backcrossed with C57BL/6J (Jackson Laboratory ...
• Interphotoreceptor matrix proteoglycans IMPG1 and IMPG2 proteolyze in the SEA domain and reveal localization mutual dependency

  Benjamin Mitchell, et al., bioRxiv - Molecular Biology 2022

  Quote: ... All mouse populations were backcrossed with C57BL/6J (Jackson Laboratory) and consistently genotyped to identify possible RD1 and RD10 mutations ...
• Generating an in vitro gut model with physiologically relevant biophysical mucus properties

  Jacob McCright, Arnav Sinha, Katharina Maisel, bioRxiv - Bioengineering 2022

  Quote: ... female C57Bl/6J mice 8-10 weeks old were purchased from Jackson Labs and allowed to acclimate for up to 14 days ...
• Mitochondria-containing Extracellular Vesicles (EV) Reduce Mouse Brain Infarct Sizes and EV/HSP27 Protect Ischemic Brain Endothelial Cultures

  Kandarp M. Dave, et al., bioRxiv - Bioengineering 2022

  Quote: Young male C57BL/6 mice (8-12 weeks) were purchased from Jackson laboratories. Mice were acclimated in our animal facilities for one week before use ...
• NF-κB-Inducing Kinase Maintains Mitochondrial Efficiency and Systemic Metabolic Homeostasis

  Kathryn M. Pflug, et al., bioRxiv - Physiology 2022

  Quote: ... Map3k14 mice were purchased from Jackson lab (B6N.129-Map3k14tm1Rds/J) and maintained by heterozygous breeding ...
• Tissue libraries enable rapid determination of conditions that preserve antibody labeling in cleared mouse and human tissue

  Theodore J. Zwang, et al., bioRxiv - Cell Biology 2022

  Quote: Male and female C57Bl/6J mice (Jackson Laboratory 000664) were used for most tissue experiments ...
• 2-hydroxyglutarate controls centromere and heterochromatin conformation and function in the male germline

  Nina Mayorek, et al., bioRxiv - Cell Biology 2022

  Quote: ... tdTomato (B6;129S6-Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/J females(stock 007905) and EYFP (B6.129X1-Gt(ROSA)26Sortm1(EYFP)Cos/J females (stock 006148) were purchased from Jackson Laboratories. All mice are on C57BL/6 background ...
• Novel ACE2 nanoparticles universally block SARS-CoV-2 variants in the human respiratory tract

  Cécile Sauvanet, et al., bioRxiv - Cell Biology 2022

  Quote: ... catalogue number #AF933) and an Alexa Fluor 488-conjugated donkey anti-goat secondary antibody (1:10,000 dilution, Jackson Laboratory, Catalog number # 305-547-003) were used for Western blotting ...
• The encoding of touch by somatotopically aligned dorsal column subdivisions

  Josef Turecek, Brendan P. Lehnert, David D. Ginty, bioRxiv - Neuroscience 2022

  Quote: ... C57Bl/J6 were obtained from Jackson Laboratories.
• Systematic Transmission Electron Microscopy-Based Identification and 3D Reconstruction of Cellular Degradation Machinery

  Kit Neikirk, et al., bioRxiv - Biophysics 2022

  Quote: ... Mice with a tamoxifen-inducible knockout of DRP1 in skeletal muscle were generated by crossing mice carrying a homozygous floxed allele of DRP1 with mice carrying a tamoxifen-inducible Cre recombinase under control of the myogenin promoter (Jackson Lab) in skeletal muscle as previously described [42,43] ...
• HIV-induced membraneless organelles orchestrate post-nuclear entry steps

  Viviana Scoca, et al., bioRxiv - Microbiology 2022

  Quote: ... Secondary antibodies used were the following: Donkey anti-Rabbit Cy3 1:1000 (Jackson Lab #711-165-152), Goat anti-Rabbit Alexa-488 1:300 (Invitrogen #A32731) ...
• The Skeletal Muscle Circadian Clock Regulates Titin Splicing Through RBM20

  Lance A. Riley, et al., bioRxiv - Physiology 2022

  Quote: ... The Bmal1lox mouse was purchased from Jackson laboratories (stock number 7668) and crossed with the skeletal muscle-specific Cre-recombinase mouse (HSA-Cre ...
• Early life exercise primes the neural epigenome to facilitate gene expression and hippocampal memory consolidation

  AM Raus, et al., bioRxiv - Neuroscience 2022

  Quote: The mouse lines used for this study are available from Jackson Labs (Emx1-IRES-Cre knock-in mice, Jackson Laboratory Stock No: 005628, and NuTRAP mice, Jackson Laboratory Stock No: 029899).
• Early life exercise primes the neural epigenome to facilitate gene expression and hippocampal memory consolidation

  AM Raus, et al., bioRxiv - Neuroscience 2022

  Quote: ... NuTRAP mice (Jackson Laboratory Stock No: 029899), and C57Bl6/J (Jackson Laboratory Stock No ...
• Early life exercise primes the neural epigenome to facilitate gene expression and hippocampal memory consolidation

  AM Raus, et al., bioRxiv - Neuroscience 2022

  Quote: Emx1-IRES-Cre knock-in mice (Jackson Laboratory Stock No: 005628), NuTRAP mice (Jackson Laboratory Stock No ...
• Lymphatic dysfunction in lupus contributes to cutaneous photosensitivity and lymph node B cell responses

  William G. Ambler, et al., bioRxiv - Immunology 2022

  Quote: ... were originally from Jackson Laboratory (JAX, Bar Harbor, Maine) and bred at our facility ...
• Early life exercise primes the neural epigenome to facilitate gene expression and hippocampal memory consolidation

  AM Raus, et al., bioRxiv - Neuroscience 2022

  Quote: ... and C57Bl6/J (Jackson Laboratory Stock No: 000664) wild type mice were obtained from Jackson Laboratories ...
• Early life exercise primes the neural epigenome to facilitate gene expression and hippocampal memory consolidation

  AM Raus, et al., bioRxiv - Neuroscience 2022

  Quote: The mouse lines used for this study are available from Jackson Labs (Emx1-IRES-Cre knock-in mice ...
• Early life exercise primes the neural epigenome to facilitate gene expression and hippocampal memory consolidation

  AM Raus, et al., bioRxiv - Neuroscience 2022

  Quote: ... wild type mice were obtained from Jackson Laboratories. Female Emx1-IRES-Cre and male NuTRAP mice were crossed to generate the Emx1-NuTRAP mice used for this study ...
• Allele-specific differential regulation of monoallelically expressed autosomal genes in the cardiac lineage

  Gayan I. Balasooriya, David L. Spector, bioRxiv - Genomics 2022

  Quote: Four week old C57BL/6J female and four week old CAST/EiJ male mice were purchased from Jackson Laboratories. C57BL/6J female mice were hormone treated and paired (five pairs ...
• Shared and distinct brain regions targeted for immediate early gene expression by ketamine and psilocybin

  Pasha A. Davoudian, Ling-Xiao Shao, Alex C. Kwan, bioRxiv - Neuroscience 2022

  Quote: ... 8-week-old C57BL/6J mice (#00064, The Jackson Laboratory) were used for the light sheet whole-brain mapping experiments ...
• Early life sleep disruption potentiates lasting sex-specific changes in behavior in genetically vulnerable Shank3 heterozygous autism model mice

  Julia S. Lord, et al., bioRxiv - Animal Behavior and Cognition 2022

  Quote: ... Wild-type C57BL/6J breeders were regularly purchased from Jackson laboratories (strain #000664). For sleep recording experiments described in Fig ...
• Early life sleep disruption potentiates lasting sex-specific changes in behavior in genetically vulnerable Shank3 heterozygous autism model mice

  Julia S. Lord, et al., bioRxiv - Animal Behavior and Cognition 2022

  Quote: ... Shank3ΔC mice are commercially available from Jackson Laboratories (strain #018398). Wild-type C57BL/6J breeders were regularly purchased from Jackson laboratories (strain #000664) ...
• Oligodendrocyte lineage cells driven by neuronal activity in selected brain regions are required for episodic memory formation

  Luendreo P. Barboza, et al., bioRxiv - Neuroscience 2022

  Quote: ... and Myrf floxed mice (The Jackson Laboratory, Bar Harbor ...
• Oligodendrocyte lineage cells driven by neuronal activity in selected brain regions are required for episodic memory formation

  Luendreo P. Barboza, et al., bioRxiv - Neuroscience 2022

  Quote: Male and female Pdgfra-CreERT2-Myrf floxed (P-Myrf) mice were obtained by crossing Pdgfra-CreERT2 (The Jackson Laboratory, Bar Harbor ...
• A novel RORγt⁺ antigen presenting cell type instructs microbiota-dependent regulatory T cell differentiation and tolerance during early life

  Blossom Akagbosu, et al., bioRxiv - Immunology 2022

  Quote: ... CD45.1 and BALB/c mice were purchased from Jackson Laboratories. Generation and treatments of mice were performed under protocol 21-05-007 and 08-10-023 ...
• Defining the chromatin and transcriptional landscape of stem cell-derived islets

  Punn Augsornworawat, et al., bioRxiv - Cell Biology 2022

  Quote: ... and with the NOD.Cg-Prkdcscid Il2rgtm1wjl/SzJ (NSG) background (Jackson Laboratories; 005557) were randomly assigned to experimental groups ...
• Long wavelength light reduces the negative consequences of dim light at night in the Cntnap2 mouse model of autism

  Huei Bin Wang, et al., bioRxiv - Neuroscience 2022

  Quote: ... RRID:IMSR_JAX:007906) expressing robust ZsGreen1 fluorescence following Cre-mediated recombination were obtained from Jackson Laboratory. The Ai6 is a Cre reporter allele designed to have a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven enhanced green fluorescent protein variant (ZsGreen1 ...
• Functional Cell Types in the Mouse Superior Colliculus

  Ya-tang Li, Markus Meister, bioRxiv - Neuroscience 2022

  Quote: ... Rorb-IRES2-Cre-D (The Jackson Laboratory, stock No: 023526) (Harris et al. ...
• Functional Cell Types in the Mouse Superior Colliculus

  Ya-tang Li, Markus Meister, bioRxiv - Neuroscience 2022

  Quote: ... Vglut2-ires-Cre (The Jackson Laboratory, stock No: 028863), Vgat-ires-Cre (The Jackson Laboratory ...
• Functional Cell Types in the Mouse Superior Colliculus

  Ya-tang Li, Markus Meister, bioRxiv - Neuroscience 2022

  Quote: ... Vgat-ires-Cre (The Jackson Laboratory, stock No: 028862), Tac1-IRES2-Cre-D (The Jackson Laboratory ...
• Functional Cell Types in the Mouse Superior Colliculus

  Ya-tang Li, Markus Meister, bioRxiv - Neuroscience 2022

  Quote: ... Tac1-IRES2-Cre-D (The Jackson Laboratory, stock No: 021877) (Harris et al. ...
• In colon cancer cells, fascin1 functions as a mechanosensor that transforms adherens junction mechanotransduction

  Amin Esmaeilniakooshkghazi, et al., bioRxiv - Cancer Biology 2022

  Quote: NOD-scid IL2Rgammanull mice (NSG) (Jackson Laboratory, Bar Harbor, ME) were injected subcutaneously with 2 x 106 Scr and shF cells and intra-splenic with 1×106 Scr and shF cells ...
• The Injured Sciatic Nerve Atlas (iSNAT), Insights into the Cellular and Molecular Basis of Neural Tissue Degeneration and Regeneration

  Xiao-Feng Zhao, et al., bioRxiv - Neuroscience 2022

  Quote: ... Sarm1/Myd88-5-/- (Jackson labs Stock No: 018069) and ROSA26-mTdt/mGFP (Jackson labs Stock No ...
• The Injured Sciatic Nerve Atlas (iSNAT), Insights into the Cellular and Molecular Basis of Neural Tissue Degeneration and Regeneration

  Xiao-Feng Zhao, et al., bioRxiv - Neuroscience 2022

  Quote: ... and ROSA26-mTdt/mGFP (Jackson labs Stock No: 007576). Mice were housed under a 12 h light/dark cycle with regular chow and water ad libitum ...
• Targeting BRPF3 moderately reverses olaparib resistance in high grade serous ovarian carcinoma

  Benjamin G. Bitler, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Intraperitoneal injections of 5 million GTFB1009 ascites cells were given to 6- to 8-week-old NOD SCID gamma (NSG) mice (Jackson Labs). Following a 7-day incubation period ...
• State-dependent modulation of activity in distinct layer 6 corticothalamic neurons in barrel cortex of awake mice

  Suryadeep Dash, Dawn M. Autio, Shane R. Crandall, bioRxiv - Neuroscience 2022

  Quote: ... Ai14 (Jackson Labs: 007908) (Madisen et al. ...
• State-dependent modulation of activity in distinct layer 6 corticothalamic neurons in barrel cortex of awake mice

  Suryadeep Dash, Dawn M. Autio, Shane R. Crandall, bioRxiv - Neuroscience 2022

  Quote: ... Ai32 (Jackson Labs: 024109) (Madisen et al. ...
• Exocyst Inactivation in Urothelial Cells Disrupts Autophagy and Activates non-canonical NF-κB

  Michael A. Ortega, et al., bioRxiv - Developmental Biology 2022

  Quote: ... as was the tdTomato Cre reporter strain (Jackson Laboratories stock #007909). The Ksp-Cre and UPK3a-GCE mouse strains were obtained from Jackson Laboratories (stock # 012237 and 015855 ...
• Exocyst Inactivation in Urothelial Cells Disrupts Autophagy and Activates non-canonical NF-κB

  Michael A. Ortega, et al., bioRxiv - Developmental Biology 2022

  Quote: ... The Ksp-Cre and UPK3a-GCE mouse strains were obtained from Jackson Laboratories (stock # 012237 and 015855 ...
• GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis

  Ricardo A. Cordova, et al., bioRxiv - Cancer Biology 2022

  Quote: ... TM00298 PCa PDX model [48] was obtained from Jackson Laboratory and male NSG mice were engrafted with ∼1 mm3 PDX tumor fragments and randomized once the tumors reached a palpable stage (∼50 – 100 mm3) ...
• Cerebellar acceleration of learning in an evidence-accumulation task

  Marlies Oostland, et al., bioRxiv - Neuroscience 2022

  Quote: ... Pcp2-Cre for Purkinje-cell specificity and Ai27D for channelrhodopsin-2 (33 animals Pcp2-Cre × Ai27D, acquired from The Jackson Laboratory, stock #010536 (RRID:IMSR_JAX:010536) and #012567 (RRID:IMSR_JAX:012567) ...
• Cerebellar acceleration of learning in an evidence-accumulation task

  Marlies Oostland, et al., bioRxiv - Neuroscience 2022

  Quote: Data came from 133 mice (males and females, 2-5 months of age at the start of experiments) of genotypes C57BL/6J (The Jackson Laboratory, Bar Harbor, ME, 40 animals), Pcp2-Cre for Purkinje-cell specificity and Ai27D for channelrhodopsin-2 (33 animals Pcp2-Cre × Ai27D ...
• Flotillin-2 regulates EGFR activation, degradation, and cancer growth

  David J. Wisniewski, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and NSG mice (Jackson labs) were housed and observed according to approved NCI-ACUC guidelines ...
• Intestinal epithelial MHC class II regulation by HDAC3 instructs microbiota-specific CD4+ T cells

  Emily M. Eshleman, et al., bioRxiv - Immunology 2022

  Quote: Conventionally-housed C57Bl/6J mice were purchased from Jackson Laboratories and maintained in our specific-pathogen free colony at Cincinnati Children’s Hospital Medical Center (CCHMC) ...
• Ketone ester-enriched diet ameliorates motor and dopamine release deficits in MitoPark mice

  Vikrant R. Mahajan, et al., bioRxiv - Neuroscience 2022

  Quote: Male C57BL/6J mice (Jackson Laboratory, strain 000664) were used to determine achievable blood ketone levels for each diet ...
• Site-1 Protease inhibits mitochondrial metabolism by controlling the TGF-β target gene MSS51

  Muhammad G. Mousa, et al., bioRxiv - Molecular Biology 2022

  Quote: ... HSA-Cre79 mice were obtained from Jackson Laboratory (B6.Cg-Tg(ACTA1-cre)79Jme/J ...
• Elongation of Very Long Chain Fatty Acids Like- 3 (Elovl3) is activated by ZHX2 and is a regulator of cell cycle progression

  Kate Townsend Creasy, et al., bioRxiv - Molecular Biology 2022

  Quote: ... or BL/6 mice expressing E2a promoter-driven Cre recombinase (E2a-Cre, Jackson Labs #003724) and then back-crossed to produce hepatocyte-specific Zhx2 knockout mice (Zhx2Δhep ...
• Elongation of Very Long Chain Fatty Acids Like- 3 (Elovl3) is activated by ZHX2 and is a regulator of cell cycle progression

  Kate Townsend Creasy, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mice homozygous with floxed Zhx2 alleles (Zhx2f/f) were bred to BL/6 mice expressing Albumin promoter-driven Cre recombinase (Alb-Cre, Jackson Labs #003574) or BL/6 mice expressing E2a promoter-driven Cre recombinase (E2a-Cre ...