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1 - 50 of 67 citations for 6 Pyrrolidin 1 yl Pyridine 3 boronic acid since 2019

• TMEM106B is increased in Multiple Sclerosis plaques, and deletion causes accumulation of lipid after demyelination

  Bridget Shafit-Zagardo, et al., bioRxiv - Neuroscience 2022

  Quote: ... Perilipin 2 (PLIN2) antibody recognizes the N-terminal amino acids 1-29 (Progen GP40, 1: 400). APC/CC1 (OP80 Millipore ...
• Distribution and restoration of serotonin-immunoreactive paraneuronal cells during caudal fin regeneration in zebrafish

  Désirée König, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Mouse anti-desmoplakin 1/2 (1:50; Progen); Rabbit anti-tp63 (1:500 ...
• Heart generation via blastocyst complementation in Mesp1/2-deficient mice

  Yuto Abe, et al., bioRxiv - Cell Biology 2023

  Quote: ... and Vimentin (GP53, Progen, 1:100, and ab45939, Abcam, 1:100) followed by secondary antibodies conjugated with Alexa 488 or 546 and DAPI (D1306 ...
• Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival

  Constantine N. Tzouanas, et al., bioRxiv - Systems Biology 2023

  Quote: ... A primary antibody already targeting K8/18 was used instead of mixing K8 & K18 1:1 (Progen, GP11; 1:400), detected with ImmPACT AMEC Red per manufacturer instructions (Vector Laboratories ...
• Neprilysin-sensitive amyloidogenic Aβ versus IDE-sensitive soluble Aβ: a probable mechanistic cause for sporadic Alzheimer’s disease

  Hiroki Sasaguri, et al., bioRxiv - Neuroscience 2021

  Quote: ... synaptophysin (1:200, PROGEN), and PSD95 (1:50) ...
• Genetic control of neuronal activity enhances axonal growth only on permissive substrates

  Francina Mesquida-Veny, et al., bioRxiv - Neuroscience 2022

  Quote: ... ChR2 (1:500, Progen), GFP (1:500 ...
• Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4

  Michio Inoue, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-p62 (PROGEN, 1:100), and anti-ubiquitinylated proteins (Enzo Life Sciences ...
• A mechanism of melanogenesis mediated by E-cadherin downregulation and its involvement in solar lentigines

  Daigo Inoue, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Desmoglein-1 (651110,Progen), anti-Desmocollin-1 antibody (HPA012891 ...
• Lesion-remote astrocytes govern microglia-mediated white matter repair

  Sarah McCallum, et al., bioRxiv - Neuroscience 2024

  Quote: ... Rabbit-PLIN2 (1:500, Progen), Goat-SOX9 (1:200 ...
• Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model

  Liliana D Ordonez, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-K18 (1/5; Progen Biotechnik), anti-ΔNp63 (1:100 ...
• MOSPD2 a new endoplasmic reticulum-lipid droplet tether functioning in LD homeostasis

  Mehdi Zouiouich, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-Perilipin3 (1:1000; GP36, Progen), mouse anti-EEA1 (1:1000 ...
• RAB6 GTPase is a crucial regulator of the mammary secretory function controlling STAT5 activation

  Surya Cayre, et al., bioRxiv - Developmental Biology 2020

  Quote: ... anti-adipophilin (Progen; #GP40; 1/100), anti-GLUT1 (Abcam ...
• Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ

  Manuel Hayn, et al., bioRxiv - Microbiology 2020

  Quote: ... p62 (1:1,000, GP62-N, ProGen), LC3a/β (1:200 ...
• Preferential lipolysis of DGAT1 over DGAT2 generated triacylglycerol in Huh7 hepatocytes

  Rajakumar Selvaraj, et al., bioRxiv - Cell Biology 2021

  Quote: ... perilipin5 (PLIN5) (1:2000, PROGEN #GP31), acyl-CoA synthetase long-chain family member 1 (ACSL1 ...
• Parkin is not required to sustain OXPHOS function in adult mammalian tissues

  Roberta Filograna, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-DNA (1:200, Progen). Sections were then incubated with secondary antibodies conjugated with Alexa 488 and Alexa 594 at a dilution of 1:500 for 2 hours at RT ...
• Late stages of the Zika virus life cycle are impaired by a selective TRPML2 agonist

  Kerstin K. Schwickert, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-p62 (ProGen Biotechnik, 1:1,000), anti-LC3 (BIOZOL ...
• Desmosomes polarize mechanical signaling to govern epidermal tissue form and function

  Joshua A. Broussard, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse P124 anti-desmoglein 1 (Progen, 651111); mouse U100 anti-desmocollin 1a/b (Progen ...
• MISTERMINATE Mechanistically Links Mitochondrial Dysfunction with Proteostasis Failure

  Zhihao Wu, et al., bioRxiv - Cell Biology 2019

  Quote: ... guinea pig anti-P62 (1:500, ProGEN), mouse anti-RpS6 (1:500 ...
• Host immune responses after suprachoroidal delivery of AAV8 in nonhuman primate eyes

  Sook Hyun Chung, et al., bioRxiv - Genetics 2020

  Quote: ... Commercial anti-AAV8 (Progen, 610160S, 1:100) and anti-GFP (Abcam ...
• Extrafollicular responses are sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus

  Lasse F. Voss, et al., bioRxiv - Immunology 2022

  Quote: ... anti-Nephrin (GP-N2, Progen, 1:100), anti-Ig (1010-08 ...
• Vinculin anchors contractile actin to the cardiomyocyte adherens junction

  Chelsea D. Merkel, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-Plakophilin 2 (1:10; Progen 651101), anti-Desmoglein 2 (1:250 ...
• CENP-A overexpression drives distinct cell fates depending on p53 status

  Daniel Jeffery, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Vimentin (N-term) 1:100 (5741S Progen). Secondary antibodies ...
• A Genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor

  Anupriya M Geethakumari, et al., bioRxiv - Biophysics 2022

  Quote: ... 1:5000) or with anti-Strep-tag mouse monoclonal antibody (anti-Strep-tag mouse monoclonal, C23.21; PROGEN-910STR; 1:5000) overnight at 4°C in dilution buffer (TBS-T containing 5% bovine serum albumin (BSA) ...
• PLB-985 neutrophil-like cells as a model to study Aspergillus fumigatus pathogenesis

  Muhammad Rafiq, et al., bioRxiv - Microbiology 2021

  Quote: ... 6 ml of this solution was carefully layered onto (avoiding any mixing) 5 ml (1:1 vol/vol) of PolymorphPrep solution (Progen) and centrifuged 50 min at 500 x g for gradient separation ...
• New insights underlying the early events of dopaminergic dysfunction in Parkinson’s Disease

  Hannah L. Dela Cruz, et al., bioRxiv - Neuroscience 2023

  Quote: ... The sections were immunostained with the primary antibody: 1/500 diluted guinea pig anti-p62/SQSTM-1 (ProGen, GP62-C) and 1/1500 chicken anti-tyrosine hydroxylase (Encor ...
• Apremilast prevents blistering in human epidermis by stabilization of keratinocyte adhesion in pemphigus

  Anna M. Sigmund, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-Desmoglein-1 mouse monoclonal (Progen, Heidelberg, Germany), anti-desmoglein-2 mouse monoclonal (Origene ...
• Generation and characterisation of an estrogen receptor-positive GEMM-derived Pten p53 null transplantable breast tumour model for therapeutic testing

  E.J. Davies, et al., bioRxiv - Cancer Biology 2019

  Quote: ... cytokeratin 18 (clone Ks18.04, 1:5, #65028, Progen), Estrogen Receptor (clone 6F11 ...
• Single-Cell RNA Sequencing Reveals Endothelial Cell Transcriptome Heterogeneity under Homeostatic Laminar Flow

  Ziqing Liu, et al., bioRxiv - Cell Biology 2020

  Quote: ... guinea pig anti-vimentin (1:100, Progen, GP53), and rabbit anti-SULF1 (1:50 ...
• NDR1/2 kinases regulate membrane trafficking, enable efficient autophagy and prevent neurodegeneration

  Flavia Roșianu, et al., bioRxiv - Neuroscience 2022

  Quote: ... guinea-pig p62 (1:400, Progen GP62-C), rabbit LC3-B (1:200 ...
• Recovery of cryo-injured rabbit urethras by biofabricated C-shaped adipose-derived mesenchymal cell structures

  Sudha Silwal Gautam, et al., bioRxiv - Bioengineering 2020

  Quote: ... desmin (1:200 rabbit polyclonal; Progen Biotechnik GmbH), pax 7 (1:1000 ...
• Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by involving an Integrin-αVβ6/TGF-β Signaling Cascade

  Camilla Schinner, et al., bioRxiv - Cell Biology 2021

  Quote: ... The following primary antibodies were incubated in antibody buffer (Intercept blocking buffer diluted 1:1 in TBS containing 0.2 % tween 20) at 4 °C overnight: Mouse anti-DSG1/2 (61002, Progen, Heidelberg, Germany), mouse anti-DSP (61003 ...
• Conserved Transcription Factors Control Chromatin Accessibility and Gene Expression to Maintain Cell Fate Stability and Restrict Reprogramming of Differentiated Cells

  Maria A. Missinato, et al., bioRxiv - Cell Biology 2021

  Quote: ... guinea pig polyclonal anti-Vimentin (Progen, GP53, 1:100); mouse anti-VIMENTIN (Santa Cruz Biotechnology ...
• G2 stem cells orchestrate time-directed, long-range coordination of calcium signaling during skin epidermal regeneration

  Jessica L Moore, et al., bioRxiv - Cell Biology 2022

  Quote: ... guinea pig anti-K10 (1:200; Progen, GP-K10), rabbit anti-pH3 (1:300 ...
• Fgf8 promotes survival of nephron progenitors by regulating BAX/BAK-mediated apoptosis

  Matthew J. Anderson, et al., bioRxiv - Developmental Biology 2022

  Quote: ... and guinea pig polyclonal Nephrin antibodies (Progen, 1:50), Alexa Fluor 488 conjugated goat anti-rabbit IgG (Thermo Fisher ...
• Non-ablative disease-modifying effects of magnetic resonance-guided focused ultrasound in neuromelanin-producing parkinsonian rodents

  Joan Compte, et al., bioRxiv - Neuroscience 2023

  Quote: ... guinea pig anti-p62 (1:1000, Progen, Cat#GP62).
• A Clock-Driven Neural Network Critical for Arousal

  Benjamin J. Bell, et al., bioRxiv - Neuroscience 2020

  Quote: ... then incubated with rabbit anti-HDC (Progen, 16045, 1:800), goat anti-ChAT (Millipore ...
• Autophagy cargo receptors are secreted via extracellular vesicles and particles in response to endolysosomal inhibition or impaired autophagosome maturation

  Tina A. Solvik, et al., bioRxiv - Cell Biology 2021

  Quote: ... guinea pig anti-p62/SQSTM1 (Progen, GP62-C; 1:1,000), rabbit anti-p62/SQSTM1 (Cell Signaling ...
• The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging

  Erna Raja, et al., bioRxiv - Developmental Biology 2022

  Quote: ... guinea pig anti-K31 (1:100, PROGEN Biotechnik, GP-hHa1), rabbit anti-collagen IV (1:200 ...
• Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling

  Jitske Jansen, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Primary antibody against nephrin (guinea pig, Progen GmbH, 1:100) was diluted in blocking solution and detected by a secondary anti-guinea pig Cy3-antibody (Jackson ImmunoResearch Laboratories Inc. ...
• Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture

  Clémentine Villeneuve, et al., bioRxiv - Developmental Biology 2022

  Quote: ... guinea-pig anti-Keratin 14 (Progen, GP-CK14; 1:300), rabbit anti-Collagen IV (Abcam ...
• Structural basis of p62/SQSTM1 helical filaments, their presence in p62 bodies and role in cargo recognition in the cell

  Arjen J. Jakobi, et al., bioRxiv - Molecular Biology 2019

  Quote: ... guinea pig anti-p62 antibody (Progen, Cat#Gp62-C#, 1:5000); rabbit anti-Actin antibody (Sigma ...
• Autophagy cargo receptors are secreted via extracellular vesicles and particles in response to endolysosomal inhibition or impaired autophagosome maturation

  Tina A. Solvik, et al., bioRxiv - Cell Biology 2021

  Quote: ... guinea pig anti-p62/SQSTM1 (Progen/Cedarlane, #GP62-C; 1:1,000), rabbit anti-StrepTag II (Abcam ...
• Epidermal basal domains organization highlights skin robustness to environmental exposure

  Sangeeta Ghuwalewala, et al., bioRxiv - Developmental Biology 2022

  Quote: ... guinea pig anti-K31 (1:100, PROGEN Biotechnik no. GP-hHa1), rabbit anti-K14 (anti-K14 (Covance ...
• Epidermal basal domains organization highlights skin robustness to environmental exposure

  Sangeeta Ghuwalewala, et al., bioRxiv - Developmental Biology 2022

  Quote: ... guinea pig anti-K31 (1:100, PROGEN Biotechnik no. GP-hHa1), rabbit anti-K14 (Covance ...
• Adeno-associated virus type 2 (AAV2) uncoating is a stepwise process and is linked to structural reorganization of the nucleolus

  Sereina O. Sutter, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-AAV VP1/VP2 (A69, ProGen, dilution for IF 1:10), anti-AAV2 Rep (Fitzgerald Industries ...
• The interferon-ɣ inducible factor 16 (IFI16) restricts adeno-associated virus serotype 2 (AAV2) transduction in an immune-modulatory independent way

  Sereina O. Sutter, et al., bioRxiv - Microbiology 2024

  Quote: ... anti-AAV2 intact particle (A20, ProGen: dilution for IF; 1:50), anti-fibrillarin (Abcam ab5821 ...
• Increasing triacylglycerol formation and lipid storage by unsaturated lipids protects renal proximal tubules in diabetes

  Albert Pérez-Martí, et al., bioRxiv - Cell Biology 2021

  Quote: ... As primary antibodies guinea pig anti-p62 (1:1000, Progen, #GP62-C) and rabbit anti-LC3 (1:500 ...
• Adeno-associated virus type 2 (AAV2) uncoating is a stepwise process and is linked to structural reorganization of the nucleolus

  Sereina O. Sutter, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-AAV VP1/VP2/VP3 (VP51, ProGen, dilution for IF 1:10), anti-AAV VP1/VP2 (A69 ...
• The role of desmoplakin for neuronal function in the dentate gyrus and anxiety-related behavior

  Keisuke Otsubo, et al., bioRxiv - Neuroscience 2023

  Quote: ... and incubated with monoclonal mouse anti-Dsp (1:50; Progen, 61003, RRID:AB_2920666), rabbit anti-NeuN (1:1000 ...
• The synaptic vesicle protein Mover/TPRG1L is associated with lipid droplets in astrocytes

  Jeremy Krohn, et al., bioRxiv - Neuroscience 2022

  Quote: ... guinea pig anti perilipin-2 (Perilipin-2; 1:1000; Progen Cat# GP40, RRID:AB_2895086), mouse anti glial fibrillary acidic protein (GFAP ...