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5951 - 6000 of 10000+ citations for Dectin 1 CLEC7A Human HEK293 Fc since 2019

• Mitochondrial, cell cycle control and neuritogenesis alterations in an iPSC-based neurodevelopmental model for schizophrenia

  Giuliana S. Zuccoli, et al., bioRxiv - Biochemistry 2020

  Quote: ... 1 mM EDTA (Sigma-Aldrich) and one tablet of protease cocktail inhibitor (Roche Diagnostics ...
• Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation

  Xiaowei Hou, et al., bioRxiv - Biochemistry 2020

  Quote: ... 1 mM benzamidine (Sigma-Aldrich), 0.5 mM 4-(2-aminoethyl ...
• Mitochondrial Proteome of Affected Neurons in a Mouse Model of Leigh Syndrome

  Alejandro Gella, et al., bioRxiv - Neuroscience 2019

  Quote: ... β-actin (1:40,000, #A1978 Sigma). After incubation with the corresponding HRP-conjugated secondary antibodies (1:10,000 ...
• Multiscale profiling of enzyme activity in cancer

  Ava P. Soleimany, et al., bioRxiv - Bioengineering 2021

  Quote: ... 1 mM marimastat (Sigma Aldrich), or protease inhibitor cocktail (P8340 ...
• Engineered human brown adipocyte microtissues improved glucose and insulin homeostasis in high fat diet-induced obese and diabetic mice

  Ou Wang, et al., bioRxiv - Bioengineering 2021

  Quote: ... 1 μM rosiglitazone (Sigma, #R2408), 0.5 mM 3-Isobutyl-1-methylxanthine (IBMX ...
• Dissecting the roles of Haspin and VRK1 in Histone H3 threonine-3 phosphorylation during mitosis

  Tyrell N. Cartwright, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1% Benzonase nuclease (E1014, Millipore), pH 8.5 ...
• Pharmacological rescue of the brain cortex phenotype of Tbx1 mouse mutants: significance for 22q11.2 deletion syndrome

  Ilaria Favicchia, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1:200 (Millipore, #06-570). Experiments were performed on serial sections 200 μm apart ...
• A missense KCNQ1 Mutation Impairs Insulin Secretion in Neonatal Diabetes

  Zhimin Zhou, et al., bioRxiv - Cell Biology 2021

  Quote: ... 0.25 μM SANT-1 (Sigma), 1 μM RA (Sigma) ...
• The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets

  Jeeyun Chung, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1 μg/ml hydrocortisone (Sigma), 5% FBS (Life Technologies 10082147 ...
• Microtubule-associated proteins promote microtubule generation in the absence of γ-tubulin in human colon cancer cells

  Kenta Tsuchiya, Gohta Goshima, bioRxiv - Cell Biology 2021

  Quote: ... and DM1A (Sigma, 1:2,000), respectively ...
• Presynaptic PTPσ organizes neurotransmitter release machinery at excitatory synapses

  Kyung Ah Han, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-GAD67 (Millipore; 1:100), anti-GABAARγ2 (Synaptic Systems ...
• Chimeric GPCRs mimic distinct signaling pathways and modulate microglia responses

  Rouven Schulz, et al., bioRxiv - Synthetic Biology 2021

  Quote: ... 1 Phosstop tablet (Sigma; 4906845001) per 10ml ...
• The rice NLR pair Pikp-1/Pikp-2 initiates cell death through receptor cooperation rather than negative regulation

  Rafał Zdrzałek, et al., bioRxiv - Plant Biology 2020

  Quote: ... 1× protease inhibitor cocktail (Sigma), 0.1% Tween 20 (Sigma ...
• A constitutively monomeric UVR8 photoreceptor allele confers enhanced UV-B photomorphogenesis

  Roman Podolec, et al., bioRxiv - Plant Biology 2020

  Quote: ... 1% [v/v] Igepal (Sigma), 1% [v/v] Protease Inhibitor Cocktail (Sigma) ...
• Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans

  Molly A. Matty, et al., bioRxiv - Neuroscience 2021

  Quote: ... 1 mM CaCl2 (Sigma C1016) and 1 mM MgSO4 (Sigma M7506) ...
• Mucoidy, a general mechanism for maintaining lytic phage in populations of bacteria

  Waqas Chaudhry, et al., bioRxiv - Microbiology 2020

  Quote: ... 1 mM MgSO4 (Sigma Aldrich), 0.1 mM CaCl2 (JT Baker) ...
• Exometabolomic analysis of decidualizing human endometrial stromal and perivascular cells

  Sarah Harden, et al., bioRxiv - Systems Biology 2020

  Quote: ... estradiol (1 nM; Sigma-Aldrich), insulin (2 µg/mL ...
• Mucin-derived O-glycans supplemented to diet mitigate diverse microbiota perturbations

  K. M. Pruss, et al., bioRxiv - Microbiology 2020

  Quote: ... 1 mg of clindamycin (Sigma) per mouse was administered via oral gavage or 200 µl of an overnight culture of C ...
• Extracellular Matrix Dysfunction in Sorsby Patient-Derived Retinal Pigment Epithelium

  Abbi L. Engel, et al., bioRxiv - Cell Biology 2021

  Quote: ... Clusterin (1:200, AB825, Millipore), CRALBP (1:1000 ...
• Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

  Paula García-Huerta, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1 mM dibutyryl-cAMP (Sigma) and 2µl/ml B27 supplement (Invitrogen ...
• Genetic dissection of Down syndrome-associated alterations in APP/amyloid-β biology using mouse models

  Justin L. Tosh, et al., bioRxiv - Neuroscience 2020

  Quote: ... β-actin (Sigma A5441, 1:60,000), and GAPDH (Sigma G9545 ...
• Functional genomic analyses highlights a shift in Gpr17-regulated cellular processes in oligodendrocyte progenitor cells (OPC) and underlying myelin dysregulation in the aged forebrain

  Andrea D. Rivera, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit-Olig2 (1:400, Millipore), goat anti-PDGFRα (1:400 ...
• Subcellular sequencing of single neurons reveals the dendritic transcriptome of GABAergic interneurons

  Julio D. Perez, et al., bioRxiv - Neuroscience 2020

  Quote: ... and benzonase (Sigma, 1:1000), heated to 75°C for 5 min and centrifuged ...
• Genome-wide mutational signatures of immunological diversification in normal lymphocytes

  Heather E Machado, et al., bioRxiv - Genomics 2021

  Quote: ... 1% penicillin/streptomycin (Sigma-Aldrich), and 1% L-glutamine (Sigma-Aldrich) ...
• c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease

  Abigail O. Smith, et al., bioRxiv - Genetics 2021

  Quote: ... SMA (1:50,000, Sigma # A5228). FITC-conjugated lectins were added with secondary antibodies ...
• Efficient Immune Cell Genome Engineering with Improved CRISPR Editing Tools

  Waipan Chan, et al., bioRxiv - Genomics 2020

  Quote: ... and 1 μM ionomycin (Sigma) (37) ...
• Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following demyelination

  Darpan Saraswat, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1% lysolecithin (Lα-lysophosphatidylcholine, Sigma) was directly injected into the dorsal and ventral funiculus of the spinal cord between two thoracolumbar vertebrae ...
• Antisense oligonucleotide therapy for SCN2A gain-of-function epilepsy

  Melody Li, et al., bioRxiv - Neuroscience 2020

  Quote: ... DAPI (1:10,000; Sigma-Aldrich) stained and mounted using ProLong Diamond antifade reagent (ThermoFisher ...
• Regulation of Hippocampal Excitatory Synapses by the Zdhhc5 Palmitoyl Acyl Transferase

  Jordan J. Shimell, et al., bioRxiv - Neuroscience 2020

  Quote: ... HA (1:1,000; Sigma, H9658), and GAPDH (1:1,000 ...
• mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination

  Gustavo Della-Flora Nunes, et al., bioRxiv - Neuroscience 2020

  Quote: ... GAPDH 1:5000 (Sigma #G9545), eIF2α 1:500 (Cell signaling #5324) ...
• Endosomal Sorting Drives the Formation of Mutant Prion Endoggresomes

  Romain Chassefeyre, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1 mg DL-cysteine (Sigma), 1 mg BSA (Sigma ...
• Inhibition of the TLR4 signalling pathway with TAK-242 reduces RSV infection and cytokine release in primary airway epithelial cells

  Lindsay Broadbent, et al., bioRxiv - Microbiology 2021

  Quote: ... SB203580 (1 μM, Sigma Aldrich) and JSH-23 (20 μM ...
• PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix

  Emily J Kay, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Vinculin (1:2000, Sigma V9131), GAPDH (1:1000 ...
• The legacy of maternal SARS-CoV-2 infection on the immunology of the neonate

  Sarah Gee, et al., bioRxiv - Immunology 2021

  Quote: ... Ionomycin (1 μg/ml) (Sigma), Brefeldin A (20 ng/ml ...
• CDK8 fine-tunes IL-6 transcriptional activities by limiting STAT3 resident time at the gene loci

  J. Martinez-Fabregas, et al., bioRxiv - Immunology 2020

  Quote: ... Ionomycin (1 μM, Sigma, I0634) and Brefeldin A (5 μg/ml ...
• Sensory neurons sprouting is dependent on osteoclast-derived extracellular vesicles involving the activation of epidermal growth factor receptors

  Estrela Neto, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1 mM pyruvate (Sigma-Aldrich), 50 ng/mL 7S NGF (Calbiochem ...
• Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity

  Collin D. Heer, et al., bioRxiv - Microbiology 2020

  Quote: ... and 1 µM PDD0017273 (Sigma). Lysates were microcentrifuged for 15 min at 4°C ...
• Characterisation of the Semliki Forest Virus-host cell interactome reveals the viral capsid protein as an inhibitor of nonsense-mediated mRNA decay

  Lara Contu, et al., bioRxiv - Molecular Biology 2021

  Quote: ... (1:15000) (Millipore, Cat#: MABE343); Rabbit polyclonal anti-GAPDH (FL-335 ...
• BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ

  Jaehyeon Jeong, et al., bioRxiv - Molecular Biology 2020

  Quote: ... aprotinin (Sigma A6279, 1:1000), and 1 mM Na-metabisulfite (Sigma) ...
• Insights into calcium signaling and gene expression in astrocytes uncovered with 129S4 Slc1a3-2A-CreERT2 knock-in mice

  Lech Kaczmarczyk, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1:2000 (Millipore, RRID: AB_2239761) in 5% normal goat serum and 0.05% Triton X-100 (Roth #3051.3 ...
• Inhibition of mTOR signaling by genetic removal of p70 S6 Kinase 1 leads to anxiety-like disorders

  Muriel Koehl, et al., bioRxiv - Neuroscience 2020

  Quote: ... or GFP (1/8000, Millipore) -labeled cells ...
• Induction Of Chronic Stress Reveals An Interplay Of Stress Granules And TDP-43 Pathological Aggregates In Human ALS Fibroblasts And iPSC-Neurons

  Antonia Ratti, et al., bioRxiv - Neuroscience 2020

  Quote: ... p62 (1:20, Sigma-Aldrich), TIAR (1:20 ...
• High fat diet worsens pathology and impairment in an Alzheimer’s mouse model, but not by synergistically decreasing cerebral blood flow

  Oliver Bracko, et al., bioRxiv - Neuroscience 2019

  Quote: ... and 1 mM AEBSF (Sigma) using a Dounce homogenizer ...
• Bma-LAD-2, an intestinal cell adhesion protein, as a potential therapeutic target for lymphatic filariasis

  Alexander F. Flynn, et al., bioRxiv - Microbiology 2021

  Quote: ... and 1% L-glutamine (Sigma) for 24 hrs at 37°C in 5% CO2 ...
• An infection-activated redox switch promotes tumor growth

  Yekaterina Kovalyova, et al., bioRxiv - Microbiology 2021

  Quote: ... and 1 mM CuSO4 (Sigma) for 1 h at RT to conjugate probe-labeled proteins with the chemically cleavable azo-tag via Cu(I)-catalyzed [3 + 2] cycloaddition (CuAAC)59 ...
• AHK5 mediates ETR1-initiated multistep phosphorelay in Arabidopsis

  Agnieszka Szmitkowska, et al., bioRxiv - Plant Biology 2021

  Quote: ... 1 μM aminoethoxyvinylglycine (AVG, Sigma) or 0.1% DMSO as control (mock ...
• Functional diversification gave rise to allelic specialization in a rice NLR immune receptor pair

  Juan Carlos De la Concepcion, et al., bioRxiv - Plant Biology 2021

  Quote: ... 1× protease inhibitor cocktail (Sigma), 0.1% Tween 20 (Sigma)) ...
• Elucidating Human Milk Oligosaccharide biosynthetic genes through network-based multiomics integration

  Benjamin P. Kellman, et al., bioRxiv - Systems Biology 2020

  Quote: ... 1 mM acceptor (lactose (Sigma) and lacto-N-neotetraose (LNnT ...
• Phenotypic and functional characterisation of first trimester human placental macrophages, Hofbauer cells

  Jake Thomas, et al., bioRxiv - Immunology 2020

  Quote: ... 1% mouse serum (Sigma-Aldrich), 5% FBS and 2mM EDTA ...
• Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells

  Carlos A. Tristan, et al., bioRxiv - Bioengineering 2020

  Quote: ... NKX2.5 (Sigma, SAB1408911, 1:50), GAPDH (Santa Cruz ...