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151 - 200 of 856 citations for 4 Chloro 2 chloromethyl 1 methoxybenzene since 2020

• Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress

  José M. Liboy-Lugo, et al., bioRxiv - Cell Biology 2024

  Quote: ... G3BP1 (Bethyl, A302-033A, 1:1000), G3BP2 (Abcam ...
• RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism

  Leïla Dumas, et al., bioRxiv - Cancer Biology 2024

  Quote: ... LARP1 (1:1000, Bethyl A302-087A), P(S240-244)-rpS6 (1:1000 ...
• Pathway choice in the alternative telomere lengthening in neoplasia is dictated by replication fork processing mediated by EXD2’s nuclease activity

  Ronan Broderick, et al., bioRxiv - Molecular Biology 2023

  Quote: ... BLM (Bethyl, A300-110A 1:2000), DNA2 (Abcam ab962488 ...
• SAFB associates with nascent RNAs to promote gene expression in mouse embryonic stem cells

  Rachel E. Cherney, et al., bioRxiv - Molecular Biology 2022

  Quote: ... SAFB (Bethyl A300-812A, 1:3000), SAFB2 (Proteintech 11642-1-AP ...
• PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription

  Isabel Mayayo-Peralta, et al., bioRxiv - Genomics 2022

  Quote: ... STAG2 (A300-158A, Bethyl, 1:1000), Actin (MAB1501R ...
• The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation

  Giovanni Ciotta, et al., bioRxiv - Cell Biology 2023

  Quote: ... SETD1A (1:500, A300-289 Bethyl), SETD1B (1:500 ...
• The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation

  Giovanni Ciotta, et al., bioRxiv - Cell Biology 2023

  Quote: ... CTR9 (1:500, A301-395A Bethyl), BPTF (1:50 ...
• The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation

  Giovanni Ciotta, et al., bioRxiv - Cell Biology 2023

  Quote: ... SETD1B (1:500, A302-281A Bethyl), CTR9 (1:500 ...
• Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting the oxysterol-binding protein OSBP

  Marko Cigler, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... PITPNB (1:2,000; Bethyl, A305-591A). Secondary antibody ...
• A monoclonal antibody raised against human EZH2 cross-reacts with the RNA-binding protein SAFB

  Rachel E. Cherney, et al., bioRxiv - Molecular Biology 2023

  Quote: ... SAFB (Bethyl A300-812A, 1:3000), TBP (Abcam ab818 ...
• Systematic mapping and modeling of 3D enhancer-promoter interactions in early mouse embryonic lineages reveal regulatory principles that determine the levels and cell-type specificity of gene expression

  Dylan Murphy, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-NANOG (Bethyl, 1:300), mouse anti-Oct4 (Santa Cruz ...
• The transmembrane domain of the desmosomal cadherin desmoglein-1 governs lipid raft association to promote desmosome adhesive strength

  Stephanie E. Zimmer, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit-anti-desmoplakin (1:1000, Bethyl A303-356A ...
• Topoisomerase I is an Evolutionarily Conserved Key Regulator for Satellite DNA Transcription

  Zhen Teng, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Top 1 (Bethyl, A302-589A), anti-TopIIa (Bethyl ...
• Coordination of transcription-coupled repair and repair-independent release of stalled RNA polymerase II in response to transcription-blocking lesions

  Yongchang Zhu, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1:1000 (Bethyl Laboratories, A301-345A); mouse anti-UVSSA polyclonal antibody ...
• Homologous recombination promotes mitotic death to suppress the innate immune response

  Radoslaw Szmyd, et al., bioRxiv - Cell Biology 2024

  Quote: ... PALB2 (Bethyl, A301-246A, 1:1000), vinculin (hVIN-1 ...
• circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA

  Trine Line Hauge Okholm, et al., bioRxiv - Molecular Biology 2024

  Quote: ... UCHL5 (Bethyl A304-099A Lot 1), YBX3 (A303-070A Lot 1) ...
• The A-C Linker controls centriole cohesion and duplication

  Lorène Bournonville, et al., bioRxiv - Cell Biology 2024

  Quote: ... POC5 (A303-341A, Bethyl, 1:250), CEP135 (24428-1-AP ...
• The A-C Linker controls centriole cohesion and duplication

  Lorène Bournonville, et al., bioRxiv - Cell Biology 2024

  Quote: ... SPICE (A303-272A, Bethyl, 1:250), CEP164 (22227-1-AP ...
• SFPQ-TFE3 gene fusion reciprocally regulates mTORC1 activity and induces lineage plasticity in a novel mouse model of renal tumorigenesis

  Kaushal Asrani, et al., bioRxiv - Cancer Biology 2024

  Quote: ... TFEB (#A303-673A, Bethyl; 1:1000), PAX8 (#ab191870 Abcam ...
• Distinct H3K9me3 heterochromatin maintenance dynamics govern different gene programs and repeats in pluripotent cells

  Jingchao Zhang, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mettl3 (Bethyl, A301- 567A, 1:2000); HA (BioLegend ...
• Distinct H3K9me3 heterochromatin maintenance dynamics govern different gene programs and repeats in pluripotent cells

  Jingchao Zhang, et al., bioRxiv - Cell Biology 2024

  Quote: ... Kdm4b (Bethyl, A301-478A, 1:2000); Kdm4c (Gifts from the Kristian Helin Lab ...
• The Hunchback temporal transcription factor determines interneuron molecular identity, morphology, and presynapse targeting in the Drosophila NB5-2 lineage

  Heather Q. Pollington, Chris Q. Doe, bioRxiv - Developmental Biology 2024

  Quote: ... chicken anti-V5 (1:800, Bethyl Laboratories ...
• The cyclin Cln1 controls polyploid titan cell formation following a stress-induced G2 arrest in Cryptococcus

  Sophie Altamirano, et al., bioRxiv - Microbiology 2021

  Quote: ... and 2 mg of total protein was incubated with 15 µl Goat anti-Myc Antibody Tag Agarose Immobilized (Bethyl, Montgomery, TX) at 4°C overnight ...
• Nuclear RNA forms an interconnected network of transcription-dependent and tunable microgels

  Mattia Marenda, et al., bioRxiv - Molecular Biology 2024

  Quote: ... immuno-fluorescence labelling was done by exposing the cells for 2 h to the primary SAF-A/HNRNPU polyclonal rabbit antibody (A300-690A, Bethyl Laboratories) at 10 μg.ml-1 and washed ...
• Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction

  Patricia S. Grace, et al., bioRxiv - Immunology 2024

  Quote: ... Antibodies were incubated at RT for 2 hours before washing the plates and adding hIgG1 detection antibody (Bethyl Laboratory #A80-104P). Plates were incubated for 1 hour with secondary antibody and washed with PBST 5 times before adding TMB substrate (BD ...
• Cytidine deaminase protects pancreatic cancer cells from replicative stress and drives resistance to DNA-targeting drugs

  A. Lumeau, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-FANCD2 (NOVUSBIO NB100-182, 1:1000) and rabbit anti-53BP1 (Bethyl A300-272A, 1:2500). DNA was stained with 4,6-diamidino-2-phenylindole (DAPI ...
• Intact nucleosomal context enables chromodomain reader MRG15 to distinguish H3K36me3 from -me2

  Sarah Faulkner, et al., bioRxiv - Biochemistry 2020

  Quote: ... and rabbit α-H3 for histone portion of membrane (Bethyl, A300-B22 A-1, 1:1000 dilution).
• Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID

  Andrea Bernardini, et al., bioRxiv - Molecular Biology 2023

  Quote: ... TAF10 (3 μg/mL, mouse mAb, 6TA 2B11), TBP (2 μg/mL, mouse mAb, 3TF1 3G3) or SUPT7L (rabbit pAb, Bethyl, A302-803A). A secondary-only control sample was incubated with BPS devoid of primary antibody ...
• Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression

  Poonam Roshan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... The precleared lysates were incubated with 20 µL of protein A/G plus agarose beads and 2 µg of BCCIP antibody (Bethyl; A302-196A). Beads were washed three times in cold MCLB buffer and resuspended in 30 µL of MCLB buffer ...
• CTCF depletion decouples enhancer-mediated gene activation from chromatin hub formation during cellular differentiation

  Magdalena A. Karpinska, et al., bioRxiv - Genomics 2024

  Quote: ... washed and pre-incubated with 2 µg of primary antibody (CTCF: Diagenode, C15410210-50; SMC1A: Abcam, ab9262; MED26: Bethyl Laboratories, A302-370) and 1 µg of spike-in antibody (Biozol ...
• Intact nucleosomal context enables chromodomain reader MRG15 to distinguish H3K36me3 from -me2

  Sarah Faulkner, et al., bioRxiv - Biochemistry 2020

  Quote: ... and rabbit α-histone H3 for histone portion of membrane (Bethyl, A300-B22 A-1, 1:1000 dilution).
• A subset of CB002 xanthine analogues bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53

  Liz J. Hernández Borrero, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p73 (1:1000, #A300-126A, Bethyl Laboratories), Noxa (1:250 ...
• CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy

  Simona Giunta, et al., bioRxiv - Cell Biology 2020

  Quote: ... ATR (1:1000; A300-138A, Bethyl Laboratories) and RNA polymerase II S2P (1:1000 ...
• Conformational transitions of the mitotic adaptor Spindly underlie its interaction with Dynein and Dynactin

  Ennio d’Amico, et al., bioRxiv - Biochemistry 2022

  Quote: ... Spindly (rabbit, Bethyl, A301-354A, 1:1000) diluted in 2.5 % BGS-PHEM-T (PHEM supplemented with 0.1% Triton-X100) ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... FUS (1:2000; Bethyl Laboratories; A300-302A), UPF1 (Cell Signaling Technologies ...
• Phenotypic analysis of an MLL-AF4 gene regulatory network reveals indirect CASP9 repression as a mode of inducing apoptosis resistance

  Joe R. Harman, et al., bioRxiv - Genomics 2020

  Quote: ... anti-GAPDH (1/10,000, Bethyl A300-641A); anti-Vinculin (1/50,000 ...
• Phenotypic analysis of an MLL-AF4 gene regulatory network reveals indirect CASP9 repression as a mode of inducing apoptosis resistance

  Joe R. Harman, et al., bioRxiv - Genomics 2020

  Quote: ... anti-MAZ (1/5000, Bethyl A301-652A); anti-GAPDH (1/10,000 ...
• Common fragile sites are characterised by faulty condensin loading after replication stress

  Lora Boteva, et al., bioRxiv - Molecular Biology 2020

  Quote: ... CAP-D3 (Bethyl, A300-604A, 1:1000) and GAPDH (Cell Signaling 2118L ...
• GSAP Regulates Amyloid Beta Production through Modulation of Amyloid Precursor Protein Trafficking

  Jerry C. Chang, et al., bioRxiv - Neuroscience 2020

  Quote: ... HA antibody (1:1,000, A190-108A, Bethyl), GAPDH antibody (1:500 ...
• Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages

  Samantha L. Bell, et al., bioRxiv - Microbiology 2020

  Quote: ... and OPTN (Bethyl, A301-829A; 1:500). Coverslips were washed three times in PBS and stained with secondary antibodies (Goat anti-Rabbit Alexa Fluor 488 ...
• Nuclear dengue virus NS5 antagonizes expression of PAF1-dependent immune response genes

  Marine J. Petit, et al., bioRxiv - Microbiology 2021

  Quote: ... PAF1 1:1000 (Bethyl Labs #A300-173A), CDC73 1:500 (GeneTex ...
• Topoisomerase 1 dependent R-loop deficiency drives accelerated replication and genomic instability

  Dan Sarni, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-53BP1 (Bethyl Laborartories, 1:100), mouse anti-cyclin A2 (Abcam ...
• Chromosomally unstable tumor cells specifically require KIF18A for proliferation

  Carolyn Marquis, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1:500 rabbit anti-KIF18A (Bethyl Laboratories), 1:1000 rabbit anti-Kif4A (Bethyl Laboratories) ...
• Chromosomally unstable tumor cells specifically require KIF18A for proliferation

  Carolyn Marquis, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1:1000 rabbit anti-Kif4A (Bethyl Laboratories), 1:1000 rabbit anti-KIF22 (Millipore Sigma) ...
• Chromosomally unstable tumor cells specifically require KIF18A for proliferation

  Carolyn Marquis, et al., bioRxiv - Cell Biology 2020

  Quote: ... 1:1000 rabbit anti-MAD2 (Bethyl Laboratories), and 1:1000 rabbit anti-Cleaved Caspase-3 (Cell Signaling Technology) ...
• Chromosomally unstable tumor cells specifically require KIF18A for proliferation

  Carolyn Marquis, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-KIF18A 1:100 (Bethyl Laboratories) at 4°C overnight ...
• A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

  Sara Marie Ambjoern, et al., bioRxiv - Cell Biology 2021

  Quote: ... PALB2 (A301-246A – M, Bethyl, 1:1000), GAPDH (Sc-25778 ...
• Charting functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

  Alexander Hanzl, et al., bioRxiv - Molecular Biology 2022

  Quote: ... BRD2 (1:1000, Bethyl Laboratories, A302-582A), SMARCA4 (1:1000 ...
• MRG proteins are shared by multiple protein complexes with distinct functions

  Maëva Devoucoux, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-PALB2 (Bethyl A301-246, 1:3000); anti-AKAP8 (Abcam ab72196 ...
• MRG proteins are shared by multiple protein complexes with distinct functions

  Maëva Devoucoux, et al., bioRxiv - Molecular Biology 2022

  Quote: ... anti-Brd8 (Bethyl A300-219A, 1:10000); anti-DMAP1 (Thermoscientific PA1-886 ...