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151 - 200 of 867 citations for 4 6 Difluoro 1 methyl 1H indazole 5 carboxylic acid since 2020

• Acute expression of human APOBEC3B in mice causes lethality associated with RNA editing

  Alicia Alonso de la Vega, et al., bioRxiv - Molecular Biology 2022

  Quote: ... yH2AX (1:200, Bethyl Labs 00059), APOBEC3B (1:200 ...
• Lis1-dynein drives corona compaction and error-correction at kinetochores

  Olivera Mitevska, Pak Wing Lam, Philip Auckland, bioRxiv - Cell Biology 2022

  Quote: ... anti-Spindly (1/1000, Rabbit, Bethyl), anti-pericentrin (1/1000 ...
• The cohesin modifier ESCO2 is stable during DNA replication

  Allison M. Jevitt, et al., bioRxiv - Cell Biology 2022

  Quote: ... hESCO2 (Bethyl Labs, rabbit,1:3000), GFP (Millipore Sigma ...
• Argonaute Binding within 3’-Untranslated Regions Does Not Predict Gene Repression

  Yongjun Chu, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 1:5000 (A302-329A, Bethyl Laboratories), anti-β-tubulin ...
• A network of DZF proteins controls alternative splicing regulation and fidelity

  Nazmul Haque, et al., bioRxiv - Molecular Biology 2022

  Quote: ... ILF3 (Bethyl Laboratories, at 1:500), β-actin (Cell Signaling ...
• A network of DZF proteins controls alternative splicing regulation and fidelity

  Nazmul Haque, et al., bioRxiv - Molecular Biology 2022

  Quote: ... ILF2 (Bethyl Laboratories, at 1:5000), ILF3 (Bethyl Laboratories ...
• Mitotic spindle assembly is controlled by the APC/C localized at the centrosome

  Thomas Tischer, Jing Yang, David Barford, bioRxiv - Cell Biology 2020

  Quote: ... Cep192 (Bethyl A302-324A, 1:1000), GFP (Abcam ab6556 ...
• Mitotic spindle assembly is controlled by the APC/C localized at the centrosome

  Thomas Tischer, Jing Yang, David Barford, bioRxiv - Cell Biology 2020

  Quote: ... Cep152 (Bethyl A302-480A, 1:500), Cep192 (Bethyl A302-324A ...
• Mitotic spindle assembly is controlled by the APC/C localized at the centrosome

  Thomas Tischer, Jing Yang, David Barford, bioRxiv - Cell Biology 2020

  Quote: ... Cep192 (Bethyl A302-324A, 1:1000), Cyclin B1 (Abcam ab72 ...
• Mitotic spindle assembly is controlled by the APC/C localized at the centrosome

  Thomas Tischer, Jing Yang, David Barford, bioRxiv - Cell Biology 2020

  Quote: ... Cep152 (Bethyl A302-480A, 1:500), Cep192 (Bethyl A302-324A ...
• The conserved herpesviral kinase ORF36 activates B2 retrotransposons during murine gammaherpesvirus infection

  Aaron M. Schaller, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Brf1 (Bethyl a301-228a, 1:1000), HA (Sigma H9658 ...
• Tripartite Inhibition of SRC-WNT-PKC Signalling Consolidates Human Naïve Pluripotency

  Jonathan Bayerl, et al., bioRxiv - Developmental Biology 2020

  Quote: ... METTL3 (A301-567A, 1:2000, Bethyl), HSP90beta (ab32568 ...
• Aurora kinase A is essential for meiosis in mouse oocytes

  Cecilia S. Blengini, et al., bioRxiv - Cell Biology 2021

  Quote: ... AURKA (1:500; Bethyl #A300-072A), ACA (1:30 ...
• Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice

  Ben Vanderkruk, et al., bioRxiv - Cell Biology 2022

  Quote: ... RBBP5 (Bethyl, A300-109A, 1:10,000), and ASH2L (Bethyl ...
• Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice

  Ben Vanderkruk, et al., bioRxiv - Cell Biology 2022

  Quote: ... WDR5 (Bethyl, A302-430A, 1:2,000), RBBP5 (Bethyl ...
• The FIGNL1-interacting protein C1orf112 is synthetic lethal with PICH and mediates RAD51 retention on chromatin

  Colin Stok, et al., bioRxiv - Cancer Biology 2022

  Quote: ... NCAPD3 (Bethyl, A300-604A, 1:500), NFATC2IP (Abcam ...
• The viral packaging motor potentiates late gene expression in Kaposi’s sarcoma-associated herpesvirus

  Chloe O. McCollum, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-PABPC4 (1:1,000; Bethyl), mouse anti-ORF26(1:500 ...
• The viral packaging motor potentiates late gene expression in Kaposi’s sarcoma-associated herpesvirus

  Chloe O. McCollum, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-XRN1 (1:1,000; Bethyl), mouse anti-CASK (1:1,000 ...
• Murine gammaherpesvirus 68 ORF45 stimulates B2 retrotransposon and pre-tRNA activation in a manner dependent on mitogen-activated protein kinase (MAPK) signaling

  Azra Lari, Britt A. Glaunsinger, bioRxiv - Microbiology 2022

  Quote: ... anti-Brf1polyclonal antibody (Bethyl, 1:1000), or anti Ha-Ras antibody (Sigma MC57 ...
• ROSALIND protects the mitochondrial translational machinery from oxidative damage

  Vicky Katopodi, et al., bioRxiv - Molecular Biology 2024

  Quote: ... XRN2 (A301-103A; Bethyl, 1:2.000), ATP5A (7H10BD4F9 ...
• Microtubule association of TRIM3 revealed by differential extraction proteomics

  Hannah L. Glover, et al., bioRxiv - Cell Biology 2023

  Quote: ... MAP4 (Bethyl, A301-488A, 1:1000), Pericentrin (Abcam ...
• Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress

  José M. Liboy-Lugo, et al., bioRxiv - Cell Biology 2024

  Quote: ... G3BP1 (Bethyl, A302-033A, 1:1000), G3BP2 (Abcam ...
• RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism

  Leïla Dumas, et al., bioRxiv - Cancer Biology 2024

  Quote: ... LARP1 (1:1000, Bethyl A302-087A), P(S240-244)-rpS6 (1:1000 ...
• Pathway choice in the alternative telomere lengthening in neoplasia is dictated by replication fork processing mediated by EXD2’s nuclease activity

  Ronan Broderick, et al., bioRxiv - Molecular Biology 2023

  Quote: ... BLM (Bethyl, A300-110A 1:2000), DNA2 (Abcam ab962488 ...
• SAFB associates with nascent RNAs to promote gene expression in mouse embryonic stem cells

  Rachel E. Cherney, et al., bioRxiv - Molecular Biology 2022

  Quote: ... SAFB (Bethyl A300-812A, 1:3000), SAFB2 (Proteintech 11642-1-AP ...
• PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription

  Isabel Mayayo-Peralta, et al., bioRxiv - Genomics 2022

  Quote: ... STAG2 (A300-158A, Bethyl, 1:1000), Actin (MAB1501R ...
• The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation

  Giovanni Ciotta, et al., bioRxiv - Cell Biology 2023

  Quote: ... SETD1A (1:500, A300-289 Bethyl), SETD1B (1:500 ...
• The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation

  Giovanni Ciotta, et al., bioRxiv - Cell Biology 2023

  Quote: ... CTR9 (1:500, A301-395A Bethyl), BPTF (1:50 ...
• The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation

  Giovanni Ciotta, et al., bioRxiv - Cell Biology 2023

  Quote: ... SETD1B (1:500, A302-281A Bethyl), CTR9 (1:500 ...
• Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting the oxysterol-binding protein OSBP

  Marko Cigler, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... PITPNB (1:2,000; Bethyl, A305-591A). Secondary antibody ...
• A monoclonal antibody raised against human EZH2 cross-reacts with the RNA-binding protein SAFB

  Rachel E. Cherney, et al., bioRxiv - Molecular Biology 2023

  Quote: ... SAFB (Bethyl A300-812A, 1:3000), TBP (Abcam ab818 ...
• Systematic mapping and modeling of 3D enhancer-promoter interactions in early mouse embryonic lineages reveal regulatory principles that determine the levels and cell-type specificity of gene expression

  Dylan Murphy, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-NANOG (Bethyl, 1:300), mouse anti-Oct4 (Santa Cruz ...
• The transmembrane domain of the desmosomal cadherin desmoglein-1 governs lipid raft association to promote desmosome adhesive strength

  Stephanie E. Zimmer, et al., bioRxiv - Cell Biology 2024

  Quote: ... rabbit-anti-desmoplakin (1:1000, Bethyl A303-356A ...
• Topoisomerase I is an Evolutionarily Conserved Key Regulator for Satellite DNA Transcription

  Zhen Teng, et al., bioRxiv - Cell Biology 2024

  Quote: ... anti-Top 1 (Bethyl, A302-589A), anti-TopIIa (Bethyl ...
• Coordination of transcription-coupled repair and repair-independent release of stalled RNA polymerase II in response to transcription-blocking lesions

  Yongchang Zhu, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1:1000 (Bethyl Laboratories, A301-345A); mouse anti-UVSSA polyclonal antibody ...
• Homologous recombination promotes mitotic death to suppress the innate immune response

  Radoslaw Szmyd, et al., bioRxiv - Cell Biology 2024

  Quote: ... PALB2 (Bethyl, A301-246A, 1:1000), vinculin (hVIN-1 ...
• circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA

  Trine Line Hauge Okholm, et al., bioRxiv - Molecular Biology 2024

  Quote: ... UCHL5 (Bethyl A304-099A Lot 1), YBX3 (A303-070A Lot 1) ...
• The A-C Linker controls centriole cohesion and duplication

  Lorène Bournonville, et al., bioRxiv - Cell Biology 2024

  Quote: ... POC5 (A303-341A, Bethyl, 1:250), CEP135 (24428-1-AP ...
• The A-C Linker controls centriole cohesion and duplication

  Lorène Bournonville, et al., bioRxiv - Cell Biology 2024

  Quote: ... SPICE (A303-272A, Bethyl, 1:250), CEP164 (22227-1-AP ...
• SFPQ-TFE3 gene fusion reciprocally regulates mTORC1 activity and induces lineage plasticity in a novel mouse model of renal tumorigenesis

  Kaushal Asrani, et al., bioRxiv - Cancer Biology 2024

  Quote: ... TFEB (#A303-673A, Bethyl; 1:1000), PAX8 (#ab191870 Abcam ...
• Distinct H3K9me3 heterochromatin maintenance dynamics govern different gene programs and repeats in pluripotent cells

  Jingchao Zhang, et al., bioRxiv - Cell Biology 2024

  Quote: ... Mettl3 (Bethyl, A301- 567A, 1:2000); HA (BioLegend ...
• Distinct H3K9me3 heterochromatin maintenance dynamics govern different gene programs and repeats in pluripotent cells

  Jingchao Zhang, et al., bioRxiv - Cell Biology 2024

  Quote: ... Kdm4b (Bethyl, A301-478A, 1:2000); Kdm4c (Gifts from the Kristian Helin Lab ...
• The Hunchback temporal transcription factor determines interneuron molecular identity, morphology, and presynapse targeting in the Drosophila NB5-2 lineage

  Heather Q. Pollington, Chris Q. Doe, bioRxiv - Developmental Biology 2024

  Quote: ... chicken anti-V5 (1:800, Bethyl Laboratories ...
• Cytidine deaminase protects pancreatic cancer cells from replicative stress and drives resistance to DNA-targeting drugs

  A. Lumeau, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-FANCD2 (NOVUSBIO NB100-182, 1:1000) and rabbit anti-53BP1 (Bethyl A300-272A, 1:2500). DNA was stained with 4,6-diamidino-2-phenylindole (DAPI ...
• Intact nucleosomal context enables chromodomain reader MRG15 to distinguish H3K36me3 from -me2

  Sarah Faulkner, et al., bioRxiv - Biochemistry 2020

  Quote: ... and rabbit α-H3 for histone portion of membrane (Bethyl, A300-B22 A-1, 1:1000 dilution).
• Intact nucleosomal context enables chromodomain reader MRG15 to distinguish H3K36me3 from -me2

  Sarah Faulkner, et al., bioRxiv - Biochemistry 2020

  Quote: ... and rabbit α-histone H3 for histone portion of membrane (Bethyl, A300-B22 A-1, 1:1000 dilution).
• A subset of CB002 xanthine analogues bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53

  Liz J. Hernández Borrero, et al., bioRxiv - Cancer Biology 2021

  Quote: ... p73 (1:1000, #A300-126A, Bethyl Laboratories), Noxa (1:250 ...
• CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy

  Simona Giunta, et al., bioRxiv - Cell Biology 2020

  Quote: ... ATR (1:1000; A300-138A, Bethyl Laboratories) and RNA polymerase II S2P (1:1000 ...
• Conformational transitions of the mitotic adaptor Spindly underlie its interaction with Dynein and Dynactin

  Ennio d’Amico, et al., bioRxiv - Biochemistry 2022

  Quote: ... Spindly (rabbit, Bethyl, A301-354A, 1:1000) diluted in 2.5 % BGS-PHEM-T (PHEM supplemented with 0.1% Triton-X100) ...
• Proximity-based labeling reveals DNA damage-induced N-terminal phosphorylation of fused in sarcoma (FUS) leads to distinct changes in the FUS protein interactome

  Michelle A. Johnson, et al., bioRxiv - Neuroscience 2021

  Quote: ... FUS (1:2000; Bethyl Laboratories; A300-302A), UPF1 (Cell Signaling Technologies ...