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1 - 50 of 158 citations for Flap endonuclease 1 FEN 1 Human since 2019

• Aberrant localization of CDC42 C-terminal variants to the Golgi apparatus drives pyrin inflammasome-dependent autoinflammation

  Masahiko Nishitani-Isa, et al., bioRxiv - Immunology 2021

  Quote: ... rabbit polyclonal anti-human pyrin (AdipoGen, 1:2000), mouse monoclonal anti Rho-GDI (Santa-Cruz Biotechnology ...
• Identification of Fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration

  Meenakshi Ambati, et al., bioRxiv - Immunology 2021

  Quote: ... The antibodies used were: mouse monoclonal anti-human caspase-1 antibody (AdipoGen; 1:1000) and mouse monoclonal antimouse caspase-1 antibody (AdipoGen ...
• Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons

  Ines Hahn, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-GTP-tubulin (hMB11; human, 1:200; AdipoGen; Dimitrov et al, 2008); anti-Shot (1:200 ...
• Syncytia formation by SARS-CoV-2 infected cells

  Julian Buchrieser, et al., bioRxiv - Microbiology 2020

  Quote: ... mouse anti-human ACE2 (Adipogen AC18F cat #AG-20A0032-C100, 1:1000), rabbit anti-human TMPRSS2 (Atlas antibodies cat# HPA035787 ...
• Human NLRP1 is activated by ZAKɑ-driven ribotoxic stress response

  Kim S. Robinson, et al., bioRxiv - Immunology 2022

  Quote: ... caspase-1 p20 (1:1000; casper-1, AdipoGen) IL1β (R&D systems ...
• RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signalling

  Kaiwen W. Chen, et al., bioRxiv - Immunology 2021

  Quote: ... caspase-1 p20 (casper-1; Adipogen; 1:1000), pro-IL-1β (AF-401-NA ...
• Clostridium difficile Toxin B activates the NLRP3 inflammasome in human macrophages, demonstrating a novel regulatory mechanism for the Pyrin inflammasome

  Matthew S.J. Mangan, et al., bioRxiv - Immunology 2021

  Quote: ... murine caspase-1 (1:1000; casper-1) from Adipogen, Pyrin (1:1000 ...
• The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection

  Marcus P. Wong, et al., bioRxiv - Immunology 2023

  Quote: ... α-mouse Caspase-1 (p20) 1:1000 (Adipogen, Casper-1), α-human Caspase-1 (p20) ...
• The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection

  Marcus P. Wong, et al., bioRxiv - Immunology 2023

  Quote: ... 1:1000 (Adipogen, Bally-1); α-Pyrin ...
• Caspase-4 dimerisation and D289 auto-processing elicits an interleukin-1β converting enzyme

  Amy H. Chan, et al., bioRxiv - Immunology 2023

  Quote: ... caspase-1 large subunit (Bally-1, mouse monoclonal, 1:1000; Adipogen), V5 (SV5-Pk1 ...
• Discovery of highly potent pancoronavirus fusion inhibitors that also effectively inhibit COVID-19 variants from the UK (Alpha), South Africa (Beta), and India (Delta)

  Francesca Curreli, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... Blot 1 and Blot 2 were immuno-detected with a human anti-ACE2 mAb (AC384) (Adipogen Life Sciences, San Diego, CA). The ECL Mouse IgG ...
• NLRP3 controls ATM activation in response to DNA damage

  Mélanie Bodnar-Wachtel, et al., bioRxiv - Cancer Biology 2020

  Quote: ... for immunoblotting with the following antibodies: anti-NLRP3 (Cryo-2, 1:1000) and anti-caspase-1 (Bally-1, 1:1000) from Adipogen, anti-ASC (1:2000 ...
• Galvanic current activates the NLRP3 inflammasome to promote type I collagen production in tendon

  Alejandro Peñín-Franch, et al., bioRxiv - Immunology 2021

  Quote: ... anti-caspase-1 (p20) mouse monoclonal (1:1000, casper-1, AG-20B-0042, Adipogen), anti-gasdermin D rabbit monoclonal (1:2000 ...
• Optogenetic activators of apoptosis, necroptosis and pyroptosis for probing cell death dynamics and bystander cell responses

  Kateryna Shkarina, et al., bioRxiv - Cell Biology 2021

  Quote: ... mouse anti-caspase-1 (clone Bally-1 AG-20B-0048-C100, AdipoGen; 1:1000), mouse anti-mCherry (ab125096 ...
• Mechanism and role of astrogliosis in the pathogenesis of HIV-associated pain One Sentence Summary: Neuron-to-astrocyte Wnt5a signaling-activated astrogliosis is essential for the development of pathological pain induced by HIV-1 gp120

  Xin Liu, et al., bioRxiv - Neuroscience 2021

  Quote: ... Caspase-1 (1:1000, Adipogen:AG-20B-0042-C100), MMP-2 (1:1000 ...
• Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes

  Rajendra Karki, et al., bioRxiv - Immunology 2020

  Quote: ... caspase-1 (AdipoGen, AG-20B-0042, 1:1000), GAPDH (CST ...
• NLRP3 inflammasome priming and activation are regulated by a novel phosphatidylinositol-dependent mechanism

  Claire Hamilton, et al., bioRxiv - Immunology 2021

  Quote: ... Caspase-1 (1:2000, AdipoGen #AG-20B-0042-C100), NLRP3 (1:2000 ...
• Gamma-interferon-inducible lysosomal thiol reductase maintains cardiac immuno-metabolic homeostasis in heart failure

  Mark Li, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Caspase-1 (Adipogen AG-20B-0042-C100; 1:1,000), OxPhos rodent antibody cocktail (ThermoFisher 1:5,000) ...
• Macrophage mediated recognition and clearance of Borrelia burgdorferinelicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

  Sarah J. Benjamin, et al., bioRxiv - Immunology 2019

  Quote: ... IL-1β (R&D AF401NA, 1:800) or caspase-1 (Adipogen AG-20B-0042, 1:1000) diluted in milk block solution ...
• Dynamin-related Irgm proteins modulate LPS-induced caspase-4 activation and septic shock

  Ryan Finethy, et al., bioRxiv - Immunology 2020

  Quote: ... rabbit anti-caspase-1 (AG-20B-0042; Adipogen; 1:1,000), mouse anti-β-actin (A2228 ...
• Identification of Fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration

  Meenakshi Ambati, et al., bioRxiv - Immunology 2021

  Quote: ... and mouse monoclonal antimouse caspase-1 antibody (AdipoGen; 1:1000).
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... anti-mouse caspase-1 (1:1,000, AG-20B-0042, Adipogen), anti-human caspase-1 (1:1,000 ...
• AIM2 Inflammasome Mediates Hallmark Neuropathological Alterations and Cognitive Impairment in a Mouse Model of Vascular Dementia

  Luting Poh, et al., bioRxiv - Neuroscience 2020

  Quote: ... Total Caspase-1 and Cleaved Caspase-1 (p33 subunit) (Adipogen, AG20B0042), Cleaved Caspase-1 (p20 subunit ...
• Inherently reduced expression of ASC restricts caspase-1 processing in hepatocytes and promotes Plasmodium infection

  Camila Marques-da-Silva, et al., bioRxiv - Immunology 2023

  Quote: ... probed with anti-mouse anti-caspase-1 (Clone Casper-1, Adipogen), anti-ASC (F-9 ...
• Biomechanical control of meiotic chromosomal bouquet and germ cell morphogenesis by the zygotene cilium

  Avishag Mytlis, et al., bioRxiv - Cell Biology 2022

  Quote: ... γTub (1:500, Adipogen), Arl13b (1:500 ...
• TNFR2 induced priming of NLRP3-inflammasome via RIPK1 leads to pyroptosis in XIAP deficient cells

  Janin Knop, et al., bioRxiv - Immunology 2019

  Quote: ... caspase-1 from Adipogen and IL-1β from RnD ...
• Extracellular Caspase-1 regulates hair follicle stem cell migration during wound-healing

  Subhasri Ghosh, et al., bioRxiv - Cell Biology 2022

  Quote: ... Casper-1 antibody (AdipoGen) and corresponding mouse IgG (CST ...
• Tubulin glutamylation is key to axon guidance via selective tuning of microtubule-severing enzymes

  Daniel Ten Martin, et al., bioRxiv - Developmental Biology 2024

  Quote: ... GT335 (1:1000, Adipogen) and PolyE (1:1200 ...
• BTK and MMP9 regulate NLRP3 inflammasome-dependent cytokine and NET responses in primary neutrophils

  Vinicius N. C. Leal, et al., bioRxiv - Immunology 2024

  Quote: ... Caspase-1 (YVAD; Adipogen) or NLRP3 (MCC950 ...
• Itaconate and fumarate derivatives exert a dual inhibitory effect on canonical NLRP3 activation in macrophages and microglia

  Christopher Hoyle, et al., bioRxiv - Immunology 2021

  Quote: ... mouse anti-mouse NLRP3 (1 μg ml−1; Adipogen, G-20B-0014-C100), rabbit anti-mouse caspase-1 (1.87 μg ml−1 ...
• Tyrosine kinase inhibitors trigger lysosomal damage-associated cell lysis to activate the NLRP3 inflammasome

  Emilia Neuwirt, et al., bioRxiv - Immunology 2022

  Quote: ... The following primary antibodies were used: anti-Caspase-1 (p20) mAb (Casper-1, Adipogen), IL-1β/IL-1F2 pAb (R&D Systems) ...
• Inhibiting NINJ1-dependent plasma membrane rupture protects against inflammasome-induced blood coagulation and inflammation

  Jian Cui, et al., bioRxiv - Immunology 2023

  Quote: ... Caspase-1 was detected using anti-Caspase-1 (Adipogen, Cat#AG-20B-0042-C100) at 1:1000 dilution ...
• NLRP3 Cys126 palmitoylation by ZDHHC7 Promotes Inflammasome Activation

  Tao Yu, et al., bioRxiv - Immunology 2023

  Quote: ... Antibodies of Caspase-1 (Casper-1) and NLRP3 (Cryo-2) were purchased from AdipoGen. Antibodies for GSDMD (EPR19828 ...
• Shigella sonnei O-antigen inhibits internalisation, vacuole escape and inflammasome activation

  Jayne L Watson, et al., bioRxiv - Microbiology 2019

  Quote: ... Mouse anti-hcaspase-1 (AdipoGen), mouse anti-caspase-4 (Santa Cruz biotechnology) ...
• Biomechanical control of meiotic chromosomal bouquet and germ cell morphogenesis by the zygotene cilium

  Avishag Mytlis, et al., bioRxiv - Cell Biology 2022

  Quote: ... glutamylated tubulin (1:400; Adipogen), Sycp3 (1:200 ...
• Metallothionein 3-zinc axis suppresses caspase-11 inflammasome activation and impairs antibacterial immunity

  Debabrata Chowdhury, et al., bioRxiv - Immunology 2021

  Quote: ... caspase-1 (AdipoGen Life Sciences), IL-1β (R&D Systems ...
• Differential modification of the C-terminal tails of different α-tubulins and their importance for microtubule function in vivo

  Mengjing Bao, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse GT335 (1:200, Adipogen), mouse DM1A (1:1,000 ...
• ER-to-lysosome Ca²⁺ refilling followed by K⁺ efflux-coupled store-operated Ca²⁺ entry in inflammasome activation and metabolic inflammation

  Hyereen Kang, et al., bioRxiv - Immunology 2023

  Quote: ... ASC (Adipogen AL177, 1: 1,000), phospho-JNK (Cell signaling #9251 ...
• Chemotherapy activates inflammasomes to cause inflammation-associated bone loss

  Chun Wang, et al., bioRxiv - Cell Biology 2023

  Quote: ... NLRP3 (1:1,000; AdipoGen,CA), AIM2 (1:1000 ...
• Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

  Allison K. Meyers, et al., bioRxiv - Immunology 2021

  Quote: ... Primary antibodies used were anti-caspase-1 p20 (AdipoGen, no. AG-20B-0042; 1:1000), LC-3 (Novus Biologicals ...
• DSS-induced inflammation in the colon drives a pro-inflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod

  Sarah Talley, et al., bioRxiv - Immunology 2021

  Quote: ... Membranes were incubated with the following primary antibodies: anti-caspase-1 (p20) (Casper-1, AdipoGen), anti-caspase-3 (#9662 ...
• RIP1 kinase activity promotes steatohepatitis through mediating cell death and inflammation in macrophages

  Liang Tao, et al., bioRxiv - Immunology 2020

  Quote: ... Anti-Caspase-1 (p20) (mouse) mAb (Casper-1) (AG-20B-0042-C100) was from Adipogen (Germany). Anti-RIP1 (mouse ...
• Transient primary cilia mediate robust Hedgehog pathway-dependent cell cycle control

  Emily K. Ho, Anaïs E. Tsai, Tim Stearns, bioRxiv - Cell Biology 2019

  Quote: ... clone GT335 (1:500, Adipogen RRID:AB_2490210), mouse IgG2a anti-Arl13b ...
• Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression

  R.K. Subbarao Malireddi, et al., bioRxiv - Cell Biology 2022

  Quote: ... caspase-1 (AG-20B-0042; Adipogen), NLRP3 (AG-20B-0014 ...
• Cellular RNA Interacts with MAVS to Promote Antiviral Signaling

  Nandan S. Gokhale, et al., bioRxiv - Immunology 2023

  Quote: ... mouse anti-MAVS (AdipoGen, 1:1000), rabbit anti-TRAF2 (CST ...
• The integration of network biology and pharmacophore modeling suggests repurposing Clindamycin as an inhibitor of pyroptosis via Caspase-1 blockage in tumor-associated macrophages

  Adrian Weich, et al., bioRxiv - Systems Biology 2024

  Quote: ... ASC (AL177, AdipoGen/Biomol, 1:1000) (1:2.500 ...
• The autophagy activator Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model

  Kiara Freitag, et al., bioRxiv - Neuroscience 2021

  Quote: ... NLRP3 (1:500, AdipoGen, AG- 20B-0014), Gasdermin D (1:500 ...
• Exon Junction Complex dependent mRNA localization is linked to centrosome organization during ciliogenesis

  Oh Sung Kwon, et al., bioRxiv - Cell Biology 2020

  Quote: ... α-Polyglutamylated tubulin (ADIPOGEN, Mouse IgG1, 1:500), α-Y14 (Santacruz ...
• Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism

  Flora Magnotti, et al., bioRxiv - Immunology 2021

  Quote: ... anti-Pyrin (Adipogen, AL196, 1: 1,000 dilution), anti-phospho S242 Pyrin (Abcam ...
• Hepatitis C virus infection is inhibited by a non-canonical antiviral signaling pathway targeted by NS3-NS4A

  Christine Vazquez, Chin Yee Tan, Stacy M. Horner, bioRxiv - Microbiology 2019

  Quote: ... mouse anti-RIG-I (1:1000, Adipogen), anti-Flag-HRP (1:2500 ...