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201 - 250 of 1413 citations for 1 2 Dihydro 1 2 tetrahydro 2H pyran 2 yl oxy ethyl 5H tetrazole 5 thione d4 since 2020

• Chemical inhibition of pathological reactive astrocytes promotes neural protection

  Benjamin L.L. Clayton, et al., bioRxiv - Neuroscience 2021

  Quote: ... GLT-1 (Novus Biologicals, NBP1-20136), ALDH1L1 (Novus Biologicals ...
• The regenerating skeletal muscle niche guides muscle stem cell self-renewal

  Alicia A. Cutler, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-ncoa7 1:100 (Novus Biologicals), anti-mest 1:100 (Invitrogen) ...
• Pleiotrophin drives a pro-metastatic immune niche within the breast tumor microenvironment

  Debolina Ganguly, et al., bioRxiv - Cancer Biology 2022

  Quote: ... (1:500, Novus Biologicals, NBP2-29429); anti-human CD31 (1:500 ...
• Tissue-engineered collagenous fibrous cap models to systematically elucidate atherosclerotic plaque rupture

  T.B. Wissing, et al., bioRxiv - Bioengineering 2021

  Quote: ... and LOX (1:100, Novus Biologicals). Sections were rinsed in PBS and incubated with 5% (w/v ...
• Adult fibroblasts retain organ-specific transcriptomic identity

  Elvira Forte, et al., bioRxiv - Cell Biology 2021

  Quote: ... TBX20 (MAB8124, Novus Biologicals, 1:200), FOXA2 (ab108422 ...
• BECLIN1 is essential for intestinal homeostasis

  Sharon Tran, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1:500 (Novus Biologicals, NB100-2220); ϕ3-Actin ...
• A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator

  Anniek Zaalberg, et al., bioRxiv - Cancer Biology 2023

  Quote: ... IKKβ (10AG2, Novus Biological, 1:000), IKKγ (2685 ...
• PARG inhibition induces nuclear aggregation of PARylated PARP1

  Sateja Paradkar, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-53BP1 (Novus Biologicals, 1:1000). For PARP1-eGFP immunofluorescence ...
• CHK2 Regulates MUS81-EME2 Function in Response to Replication Stress and BRCA2 Deficiency

  Eva Malacaria, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-SLX4 (Novus Biologicals, 1:2000), anti-EME1 (Santa Cruz Biotechnology ...
• Nociceptive neurons interact directly with gastric cancer cells via a CGRP/Ramp1 axis to promote tumor progression

  Xiaofei Zhi, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-NF200 (1:200, Novus Biologicals), anti-Substance P (1:200 ...
• Unraveling LIS1-Lissencephaly: Insights from Cerebral Organoids Suggest Severity- Dependent Genotype-Phenotype Correlations, Molecular Mechanisms and Therapeutic Strategies

  Lea Zillich, et al., bioRxiv - Neuroscience 2024

  Quote: ... p-VIM (1:500, Novus biologicals), TPX2 (1:500 ...
• Altered astrocytic and microglial homeostasis characterizes a decreased proinflammatory state in bipolar disorder

  Quentin Amossé, et al., bioRxiv - Neuroscience 2023

  Quote: ... GFAP (Novus Biologicals, NBP233184DL594, 1:300). In Situ Hybridization was then performed overnight ...
• Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration

  Marco Leibinger, et al., bioRxiv - Neuroscience 2023

  Quote: ... GFP (1:500; Novus Biologicals, RRID:AB_10128178), NeuN (1:500 ...
• Neutrophils in the brain are sources of neuroprotective molecules and demonstrate functional heterogeneity during chronic Toxoplasma gondii infection

  Kristina V. Bergersen, et al., bioRxiv - Immunology 2022

  Quote: ... Rabbit SLPI (1:200, Novus Biologicals); and Rabbit TJP1 (1:200 ...
• Neutrophils in the brain are sources of neuroprotective molecules and demonstrate functional heterogeneity during chronic Toxoplasma gondii infection

  Kristina V. Bergersen, et al., bioRxiv - Immunology 2022

  Quote: ... Chicken GAP43 (1:200, Novus Biologicals); Rabbit SLPI (1:200 ...
• Fancm regulates meiotic double-strand break repair pathway choice in mammals

  Vanessa Tsui, et al., bioRxiv - Genetics 2022

  Quote: ... FANCD2 (Novus Biologicals at 1:50). After immunostaining ...
• Distinctive chaperonopathy in skeletal muscle associated with the dominant variant in DNAJB4

  Michio Inoue, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-p62 (Novus Biologicals, 1:1000), and anti-TDP-43 (Proteintech ...
• CLIP-Seq Analysis Enables the Design of Ribosomal RNA Bait Oligonucleotides That Protect Against C9ORF72 ALS/FTD-Associated Poly-GR Pathophysiology

  Juan A. Ortega, et al., bioRxiv - Neuroscience 2022

  Quote: ... rRNA (mouse, 1:1000, Novus Biologicals), fibrillarin (rabbit ...
• ARPC5 Isoforms and Their Regulation by Calcium-Calmodulin-N-WASP Drive Distinct Arp2/3-dependent Actin Remodeling Events in CD4 T Cells

  Lopamudra Sadhu, et al., bioRxiv - Immunology 2022

  Quote: ... 1:500 (#NBP1-69003, Novus Biologicals), mouse anti-WAVE2 ...
• MARCH5-dependent NLRP3 ubiquitination is an essential step for NEK7 docking on the mitochondria

  Yeon-Ji Park, et al., bioRxiv - Immunology 2023

  Quote: ... Caspase-1 (Novus biologicals, NBP2-75014), mouse TNF-α (BD OptEIA ...
• Aging-associated Decline in Vascular Smooth Muscle Cell Mechanosensation is Mediated by Piezo1 Channel

  Ngoc Luu, et al., bioRxiv - Bioengineering 2023

  Quote: ... Piezo1 (1:25; NBP178446, Novus Biologicals), alpha-actinin 2 (1:100 ...
• Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

  Fumiyuki Hatanaka, et al., bioRxiv - Bioengineering 2023

  Quote: ... 1:200 (NB110-89724, Novus Biologicals).
• Biophysical basis for the induction of glioblastoma-like phenotype in astrocytes

  Laurent Starck, et al., bioRxiv - Neuroscience 2023

  Quote: ... GFAP (Novus Biologicals, 1:1000 dilution), EAAT2 (Santa Cruz Biotechnology ...
• Vascular endothelial growth factor-D improves lung vascular integrity during acute lung injury

  Yifan Yuan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Angiopoietin-1 (Novus Biologicals, #923-AN), TNF-α (R&D Systems ...
• AAV-DJ is Superior to AAV9 for Targeting Brain and Spinal Cord, and De-Targeting Liver Across Multiple Delivery Routes in Mice

  Monika Chauhan, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1:100 (#NB300-141, Novus Biologicals), exclusive staining of astrocytes ...
• ErbB2/HER2 expression level determines CDK4-inhibitor sensitivity and cyclin D1 and c-Myc dependency at the G1/S transition

  Ayaka Nagasato-Ichikawa, et al., bioRxiv - Cancer Biology 2024

  Quote: ... RB1 (1:1000; NOVUS biologicals; #SPM353), cyclin D1 (1:1000 ...
• BECLIN-1 is Essential for the Maintenance of Gastrointestinal Epithelial Integrity by Regulating Endocytic Trafficking, F-actin Organization and Lysosomal Function

  Juliani Juliani, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1:500 (Novus Biologicals, NB100-2220); E-CADHERIN ...
• The circadian gene Dec2 promotes pancreatic cancer dormancy by regulating tumor cell antigen presentation to facilitate immune evasion

  Chris R. Harris, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and TRA-1-60 (Novus Biologicals) were labeled for immunofluorescent staining with Sulfo-Cyanine5 NHS ester and Sulfo-Cyanine3 NHS ester respectively (both Lumiprobe) ...
• Arenavirus nucleoprotein localizes to mitochondria

  Francesca Baggio, et al., bioRxiv - Microbiology 2020

  Quote: ... incubated 15 min at RT with DAPI (Novus Biologicals, 1 μg/μl, diluted 1:10000 in methanol), and washed twice with milli-Q water prior to mounting with FluoreGuard mounting medium (Scytek Laboratories) ...
• Ubiquitin ligases and a processive proteasome facilitate protein clearance during the oocyte-to-embryo transition in Caenorhabditis elegans

  Caroline A. Spike, et al., bioRxiv - Developmental Biology 2022

  Quote: ... at a 1:2,000-1:4,000 dilution and rabbit anti-GFP NB600-308 (Novus Biologicals, Littleton, CO) at a 1:4,000 dilution ...
• Immune-mediated Tubule Atrophy Promotes Acute Kidney Injury to Chronic Kidney Disease Transition

  Leyuan Xu, et al., bioRxiv - Pathology 2022

  Quote: ... Western blot analysis was completed with antibodies selectively against TIM-1/KIM-1/HAVCR (#AF1817, Novus Biologicals) and GAPDH (#51332 ...
• Susceptibility to inflammatory bowel diseases promotes invasive carcinomas in a murine model of ATF6-driven colon cancer

  Janine Kövilein, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Sections were co-stained with anti-Ulex Europeaus Agglutinin 1 (UEA1, Rhodamine-conjugated, 1:1000; Novus Biologicals) and counterstained with 4,6-diamidino-2-phenylindole (DAPI ...
• Trans-generational inheritance of centromere identity requires the CENP-A N-terminal tail in the C. elegans maternal germ line

  Reinier F. Prosée, et al., bioRxiv - Genetics 2020

  Quote: ... Primary antibodies (anti-HA, Sigma-Aldrich mAb 3F10, 1:1000; anti-OLLAS, Novus Biologicals NBP1-06713B, 1:1000) were incubated overnight at 4 °C ...
• Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment

  William L. Hwang, et al., bioRxiv - Genomics 2020

  Quote: ... 1:40 anti-panCK-Alexa Fluor 532 (clone AE-1/AE-3; Novus Biologicals, cat. no. NBP2-33200AF532), 1:40 anti-CD45-Alexa Fluor 594 (clone 2B11 + PD7/26 ...
• Lysosomal Degradation Pathways Target Mutant Calreticulin and the Thrombopoietin Receptor in Myeloproliferative Neoplasms

  Amanpreet Kaur, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti- SQSTM1/p62 (CST 5114, 1:10000 dilution) and anti-LC3 (Novus biologicals NB100- 2220, 1:10000 dilution) antibodies for detection of p62 and LC3 ...
• Enhanced Complement Expression in the Tumor Microenvironment Following Neoadjuvant Therapy: Implications for Immunomodulation and Survival in Pancreatic Ductal Adenocarcinoma

  Xiaofei Zhang, et al., bioRxiv - Genomics 2023

  Quote: ... 1:20 anti-panCK-Alexa Fluor 532 (clone AE-1/AE-3; Novus Biologicals, cat. no. NBP2-33200AF532), and 1:100 anti-αSMA-Alexa Fluor 647 (clone 1A4 ...
• In Vitro Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40

  Jennifer E. Wu, et al., bioRxiv - Immunology 2023

  Quote: ... Primary antibodies against the following proteins were used: GAPDH (1:1000; CST) and Bhlhe40 (1:500; Novus Biologicals) in 1% non-fat milk in TBST ...
• An immature subset of neuroblastoma cells synthesizes retinoic acid and depends on this metabolite

  Tim van Groningen, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and MYCN (Novus Biologicals, 23960002, 1:300). Images were acquired using an Olympus BX63 microscope and DP80 camera along with the CellSense Dimension imaging software.
• Tuba1a is uniquely important for axon guidance through midline commissural structures

  Georgia Buscaglia, et al., bioRxiv - Developmental Biology 2020

  Quote: ... Map2 (Novus Biologicals, NB300-213; 1:2,000). Primary antibodies were diluted in blocking buffer and incubated overnight at 4°C in a humidified chamber ...
• Aryl Hydrocarbon Receptor Blocks Aging-Induced Senescence in the Liver and Fibroblast Cells

  Ana Nacarino-Palma, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and anti-NANOG (Novus Biologicals 1:100). Following washing in PBS-T ...
• Rapidly induced drug adaptation mediates escape from BRAF inhibition in single melanoma cells

  Chen Yang, et al., bioRxiv - Cell Biology 2020

  Quote: ... FANCD2 (1:500) (Novus Biologicals, #NB100-182), γ-H2AX (1:400 ...
• A septin GTPase scaffold of dynein-dynactin motors triggers retrograde lysosome transport

  Ilona A. Kesisova, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-SEPT9 (1:200; Novus Biologicals), mouse anti-SEPT9 clone 10C10 (1:100 ...
• Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

  Allison K. Meyers, et al., bioRxiv - Immunology 2021

  Quote: ... TUFM (Novus Biologicals, no. CL2242; 1:500), GAPDH (Invitrogen ...
• Ubiquitin specific protease 1 expression and function in T cell immunity

  Kyla D Omilusik, et al., bioRxiv - Immunology 2021

  Quote: ... Wdr48 (1:1000; NBP1-81404, Novus Biologicals) or β-actin (1:1000 ...
• ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations

  Coline Arnould, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 53BP1 (Novus Biologicals NB100-305 1:1000), SCC1 (Abcam ab992 1:500 ...
• A nuclear role for the Argonaute protein AGO2 in mammalian gametogenesis

  Kimberly N Griffin, et al., bioRxiv - Developmental Biology 2021

  Quote: ... AK7 (Novus Biologicals, NBP2-92176, 1: 3000), GTSF1 (NOVUS Biologicals ...
• TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

  Xiaochen Fan, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and Laminin (1 μg/mL, Novus Biological) coated dishes ...
• Signaling from the RNA sensor RIG-I is regulated by ufmylation

  Daltry L. Snider, et al., bioRxiv - Immunology 2022

  Quote: ... R-anti-UFL1 (Novus Biologicals, 1:1000), R-anti-UFM1 (Abcam ...
• Rhes protein transits from neuron to neuron and facilitates mutant huntingtin spreading in the brain

  Uri Nimrod Ramírez-Jarquín, et al., bioRxiv - Neuroscience 2021

  Quote: ... mCherry (1:5000, Novus Biologicals, #NBP2-25157), Flotillin (1:1000 ...
• Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens

  Aereas Aung, et al., bioRxiv - Immunology 2021

  Quote: ... 1:75 anti-ADAM10 (NBP176973, Novus Biologicals), 1:75 anti-MMP14 (ab51074 ...