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Citations for Bachem :
1 - 49 of 49 citations for 6 Chloro 3H imidazo 4 5 b pyridine since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Developmental Biology 2023Quote: ... inhibition of NOTCH signalling in P1 organoids was achieved by adding either 50 µM [(2R,4R,5S)-2-benzyl-5-(Boc-amino)-4-hydroxy-6-phenyl-hexanoyl]-Leu-Phe-NH2 trifluoroacetate salt (L-685,458; Bachem) or 10 µM Deshydroxy LY-411575 (DBZ ...
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bioRxiv - Synthetic Biology 2022Quote: ... H-p-Chloro-DL-Phe-OH (p-Cl-Phe) was purchased from Bachem (Switzerland).
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bioRxiv - Biophysics 2022Quote: ... B-type natriuretic peptide (4095916, Bachem, Switzerland); cardiac troponin I (Z03320 ...
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bioRxiv - Biochemistry 2020Quote: ... and fluorescein 5(6)-carbonyl-Thr-Glu-Ser-Glu~Ser-Arg-Gly-Ala-Ile-Tyr-Lys-Lys-N,N,N0,N0-tetramethyl-6-carboxyrhodamine-NH2 (FAM-TESE ~SRGAIYKK-TAMRA, ADAMTS-5) (custom-synthesized by Bachem, Bubendorf, Switzerland) with an excitation wavelength of 485 nm and an emission wavelength of 538 nm ...
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bioRxiv - Cell Biology 2019Quote: ... L-Har and TRAP-6 were purchased from Bachem. ADP ...
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bioRxiv - Physiology 2020Quote: ... Chymotrypsin (Suc-AAPF-AMC) and Cathepsin B substrates (AMC-Arg2) were obtained from Bachem AG (Bubendorf ...
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bioRxiv - Neuroscience 2021Quote: The synthetic GLP1 analogue Exendin-4 (Ex-4; 200-600 nM; Bachem, Torrance, CA) was bath-applied to activate GLP1Rs ...
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bioRxiv - Synthetic Biology 2021Quote: ... 4-Amino-L-phenylalanine (Bachem), (S)-2-amino-6-((2-azidoethoxy)carbonylamino)hexanoic acid (Iris Biotech) ...
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bioRxiv - Neuroscience 2023Quote: ... or CCK (5 μg/kg) (BACHEM). Behavioral tests were usually performed 20-30 min after drug injection ...
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bioRxiv - Neuroscience 2021Quote: OXT (0.3 IU/5 μL; Bachem, Switzerland) was administered intranasally ...
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bioRxiv - Neuroscience 2022Quote: ... at baseline and during perfusion of the high affinity GLP-1R agonist Exendin-4 (Ex-4; 100nM; catalog #4044219, Bachem, Torrance, CA). The baseline I–V was subtracted from the I–V during Ex-4 to determine the reversal potential of the Ex-4-mediated current ...
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bioRxiv - Biophysics 2022Quote: ... 4 mg of BzF (MW: 269.3; Bachem, Bubendorf, Switzerland) were dissolved in 300 μL of HCl (1M) ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... Amino-4-methylcoumarin (Ala–AMC) was purchased from Bachem. Briefly ...
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bioRxiv - Biochemistry 2020Quote: 5 mg of Aβ1-40 (BACHEM, H-1994) was dissolved in 500 μL of hexafluoro-2-propanol (HFIP ...
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bioRxiv - Biochemistry 2021Quote: 5 mg of Aβ1-40 (BACHEM, H-1994), 1 mg of Arctic Aβ1-40 (BACHEM ...
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bioRxiv - Cancer Biology 2020Quote: ... and 500 µM mouse PAR-4-amide (Bachem, Torrance, CA) at 37°C for 45 minutes to stimulate release of granular contents.
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bioRxiv - Immunology 2021Quote: PADRE peptide (AKFVAAWTLKAAA) and the immunodominant class I peptide of C57BL/6 mice (SIINFEKL) were synthesized by Bachem AG (Bubendorf ...
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bioRxiv - Cell Biology 2023Quote: ... sterile membrane damage was induced with 5 mM LLOMe (Bachem) as described in (6) ...
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bioRxiv - Microbiology 2022Quote: ... discoideum was induced using 4.5–5 mM of LLOMe (Bachem) from a 10-fold concentrated solution that was added 5 min after the start of imaging ...
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bioRxiv - Cell Biology 2024Quote: ... Cultures with 5×10 cells/pellet received daily medium exchange with or without 6 hours of prior PTHrP(1-34) treatment (2.5 nM in water, Bachem, Germany) from day 7 onward as described before [9] (Fig ...
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bioRxiv - Pharmacology and Toxicology 2020Quote: Z-RLRGG-7-amino-4-methyl-courmarin (peptide-AMC) was purchased from Bachem. Ubiquitin−7-amino-4-methylcourmarin (Ub-AMC ...
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bioRxiv - Biochemistry 2022Quote: Hydrolysis of the fluorogenic-peptide substrates suc-LLVY-AMC (7-amino-4-methylcoumarin; Bachem) was quantified to determine the proteolytic activity of proteasomes ...
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bioRxiv - Genomics 2020Quote: ... the cells were incubated for 1 h in 5 μg/mL αF (Bachem) to stop the cell cycle ...
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bioRxiv - Microbiology 2022Quote: ... which was synthesized by incorporating Fmoc-beta-(7- methoxycoumarin-4-yl)-Ala-OH (Mca, Bachem) at position 10 and Fmoc-Cys(Trt)-OH (Novabiochem ...
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bioRxiv - Neuroscience 2024Quote: ... Thirty mins after the first record, voles were re-injected intraperitoneally OT 1 mg/kg (Leuner, Caponiti, & Gould, 2012) (Bachem, 50-56-6), and pups were introduced 30 min later to record behaviors ...
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bioRxiv - Cell Biology 2022Quote: ... Neonatal C57BL/6 mice (3 days after birth) were injected ip with NaCl or BNP every two days (1µg/2g; Bachem; synthetic mouse BNP (1-45) peptide (catalog number H-7558)) ...
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bioRxiv - Biochemistry 2022Quote: ... Thrombin substrate benzyloxycarbonyl-glycyl-glycyl-arginine 7-amido-4-methylcoumarin (ZGGR-AMC) was purchased from Bachem AG ...
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bioRxiv - Physiology 2019Quote: ... 5 Na3citrate and 30 µM FMRFamide (H-Phe-Met-Arg-Phe-NH2 acetate salt, Bachem), pH 4.83 ...
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bioRxiv - Neuroscience 2019Quote: ... N-succinyl-Leu-Leu-Val-Tyr-7-amino-4-methylcoumarin (Suc-LLVY-AMC) substrate was used (BACHEM). GST-Ubl and His-UIM constructs were a gift from the Alfred Goldberg lab ...
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bioRxiv - Cell Biology 2022Quote: ... TA substrates were generated that contained the unnatural amino acid and photocrosslinker 4-Benzoylphenylalanine (BpA) (Bachem, Switzerland), which was incorporated into the TMD by amber stop codon suppression in the PURExpress system lacking all release factors (ΔRF123 ...
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bioRxiv - Neuroscience 2024Quote: ... native amino acids at the following CpxII positions were replaced by 4-Benzoyl-L-Phenylalanin (BPA Bachem) as described by Malsam et al. ...
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bioRxiv - Biochemistry 2020Quote: The Amyloid Beta (1-42) peptide (Aβ42) was purchased in 5 mg batches from Bachem (Germany). This was aliquoted in 0.5 mg stock batches and frozen at -20°C ...
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bioRxiv - Neuroscience 2019Quote: ... 0.5 µM glutamine and penicillin/streptomycin (supplemented NB) and either with 4 mM L-azidohomoalanine (L-AHA) (Bachem) or 4 mM L-Methionine (Sigma-Aldrich ...
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Activation of innate immune cGAS-STING pathway contributes to Alzheimer’s pathogenesis in 5×FAD micebioRxiv - Neuroscience 2022Quote: ... The conditioned medium from the primary activated microglia (MCM) treated with 5 μM oligomeric Aβ (4090148.1000, Bachem) were collected and added to primary astrocytic cultures for 24 h ...
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bioRxiv - Immunology 2021Quote: ... and incubated with the thrombin substrate Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride (0.42 mM) (Bachem AG, Switzerland) and CaCl2 (15 mM ...
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bioRxiv - Biochemistry 2022Quote: ... Cells harboring pEVOL-pBpF and a plasmid encoding an RseP(E23Q)-HM derivative were grown at 30°C for 4 h in M9 medium containing 0.5 mM p-benzoyl-L-phenylalanine (pBPA; Bachem AG). After adding 100 μg/mL spectinomycin to stop further protein synthesis ...
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Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptorbioRxiv - Biochemistry 2021Quote: Enzymatic activity of ACE2 was determined and quantified as described previously,37 using 100 μM 7-methoxycoumarin-4-yl-acetyl-Ala-Pro-Lys-2,4-dinitrophenyl (Bachem, Switzerland) as substrate.
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bioRxiv - Physiology 2021Quote: PRP was diluted in phosphate buffered saline (PBS; 1:40) and incubated with protease-activated receptor-4 activating peptide AYPGKF amide (PAR4-amide, 200 μM; Bachem) or PBS for 20 min at 37°C in presence of anti-CD62P-BV421 (clone RB40.34 ...
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bioRxiv - Neuroscience 2022Quote: ... bilaterally delivered sterile saline (catalog #07-892-4348, Patterson Veterinary, Devens, MA) or Exenatide acetate (Ex-4; catalog #4044219, Bachem) in 0.25µl volume ...
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bioRxiv - Cell Biology 2019Quote: ... 1 μg lysate was incubated with 100 μM Z-Gly-Pro-Arg-7-(4-methyl)-coumarylamide (MCA) (Bachem, St Helens, UK), a specific substrate for cathepsin K ...
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bioRxiv - Biochemistry 2021Quote: ... Plasma was incubated with the thrombin substrate Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride (0.42 mM) (Bachem AG, Switzerland) and CaCl2 (15 mM ...
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bioRxiv - Biophysics 2021Quote: ... The top fraction reached a concentration of 1 mg/mL and 3.6 µL supplemented with 5 mM of the dipeptide Alanine-Phenylalanine (Bachem) was applied to glow discharged gold holey carbon 2/1 300-mesh grids (Quantifoil) ...
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bioRxiv - Cell Biology 2020Quote: ... RIPK2 knock-out and FLAG-RIPK2 knock-in (hetero- and homozygous) mice were administered MDP (5 mg/kg, i.p. in 200 μL PBS, Bachem) or PBS and sacrificed after 4 hours ...
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bioRxiv - Systems Biology 2021Quote: ... were prepared by mixing 8-arm 40 kDa PEG-Nb with 5 kDa PEG-dithiol crosslinker (JenKem) and 2 mM CRGDS cell adhesive peptide (Bachem) at a 0.99:1 thiol-to-ene ratio in phosphate buffered saline (PBS ...
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bioRxiv - Cell Biology 2020Quote: ... The chymotrypsin-like activity of the proteasome was detected by incubating the gel in overlay buffer (20 mM Tris, 5 mM MgCl2) containing 100 μM Suc-LLVY-AMC (Bachem) for 30 min at 37°C ...
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bioRxiv - Physiology 2021Quote: ... Half of the mice also received a 1,000-fold excess (5 nmol) of non-radioactive glucagon in combination with 125I-Glucagon (Bachem, Switzerland) in the same injection to test for specific binding ...
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bioRxiv - Cell Biology 2020Quote: ... After 16h beads were washed 5 times with IP buffer and eluted twice with 250 ul of 1 mg/ml 3x-FLAG peptide (Bachem) in TBS pH 7.5 and eluates were pooled.
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bioRxiv - Neuroscience 2021Quote: ... 5-Fluorescein-amyloid-β protein (Aβ 1-40) (4090152) and amyloid-β protein (Aβ 1-40) (4014442) were obtained from Bachem. Aβ (1-40 ...
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bioRxiv - Cell Biology 2021Quote: ... 4 ug protein were incubated with 50 uM Suc–Leu–Leu–Val–Tyr– AMC peptide substrate (chymotrypsin-like activity; Bachem, cat. no. I-1395) or 50 uM Ac– NIe–Pro–NIe–Asp–AMC (caspase-like activity ...