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1 - 11 of 11 citations for 6 oxopiperidine 3 carboxylic acid since 2019

• Pharmacodynamic Markers of LRRK2 Inhibition in Biofluids

  Shijie Wang, et al., bioRxiv - Neuroscience 2020

  Quote: Di-docosahexaenoyl (22:6) bis (monoacylglycerol) phosphate (di-22:6-BMP) was measured in plasma and exosome-depleted urine and CSF by ultra-performance liquid chromatography – tandem mass spectrometry (UPLC-MS/MS) ...
• LRRK2 Kinase Activity Regulates Parkinson’s Disease-Relevant Lipids at the Lysosome

  Michael T. Maloney, et al., bioRxiv - Neuroscience 2022

  Quote: ... The resulting graphs for m/z 865.502 (corresponding to BMP 22:6/22:6) and m/z 834.530 (corresponding to PS 40:6 ...
• Hemagglutinin stability determines influenza A virus susceptibility to a broad-spectrum fusion inhibitor Arbidol

  Li Zhenyu, Li Tian, Liu Meisui, Ivanovic Tijana, bioRxiv - Microbiology 2022

  Quote: ... sn-(1-oleoyl-2-hydroxy)-glycerol-3-phospho-sn-3′-(1′-oleoyl-2’-hydroxy)-glycerol (ammonium salt) (18:1 BMP (R,R); Avanti Polar Lipids) ...
• Distribution of droplets and immune responses after aerosol and intra-nasal delivery of influenza virus to the respiratory tract of pigs

  Veronica Martini, et al., bioRxiv - Immunology 2020

  Quote: ... Inhale/Exhale ratio (I/E) 1/3) or a 20 kg pig (150 ml Vt, 25 BMP, I/E ratio=1/3). Drug deposition on a filter ...
• PLD3 and PLD4 synthesize S,S-BMP, a key phospholipid enabling lipid degradation in lysosomes

  Shubham Singh, et al., bioRxiv - Biochemistry 2024

  Quote: ... Signals in the lysosomes (e.g., BMP, DQ-BSA or galectin-3) were quantified by masking the signal for the lysosomal marker LAMP1 or LysoTracker Red DND-99 (Invitrogen #L7528).
• 3D-printed polymeric scaffolds with optimized architecture to repair a sheep metatarsal critical-size bone defect

  Charlotte Garot, et al., bioRxiv - Bioengineering 2022

  Quote: ... and BMP50 (n = 3 3D mini-scaffolds per geometry and per BMP-2 concentration). The homogeneity of BMP-2 loading inside the film-coated 3D mini-scaffolds was assessed using a BMP-2 loading solution containing 5% of BMP-2Rhod and a fluorescence macroscope (Macrofluo Z16 Apo ...
• Exosome-mediated release of bis(monoacylglycerol)phosphate is regulated by LRRK2 and Glucocerebrosidase activity

  Elsa Meneses-Salas, et al., bioRxiv - Neuroscience 2023

  Quote: ... Primary antibodies diluted in PBS with 1% BSA (for immunofluorescence) or 5% skim milk (for immunoblotting) were mouse anti– lysobisphosphatidic acid (anti-BMP) clone 6C4 1:1000 (EMD Millipore ...
• Recording morphogen signals reveals origins of gastruloid symmetry breaking

  Harold M. McNamara, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Recording windows were either 90 min (for Wnt recording) or 3 h (for BMP and Nodal). Doxycycline was washed out with two successively 150 µL media changes ...
• 3D printed scaffold combined to 2D osteoinductive coatings to repair a critical-size mandibular bone defect

  Michael Bouyer, et al., bioRxiv - Bioengineering 2020

  Quote: ... two conditions were further studied in larger groups with an intermediate dose of BMP-2 (loading at 50 μg/ cm3 and 110 μg/ cm3) (n=6 for low BMP-2 dose, n=5 for high dose) to perform statistical analysis ...
• Neural tube organoids self-organise floorplate through BMP-mediated cluster competition

  Teresa Krammer, et al., bioRxiv - Developmental Biology 2023

  Quote: ... under accession codes GSExxxxxx (FOXA2+ vs FOXA2- cells at Day 5, Figure 3) and GSExxxxxx (FOXA2+ vs FOXA2- cells after BMP perturbations, Figure 4).
• Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids

  Yuling Han, et al., bioRxiv - Microbiology 2020

  Quote: ... in the presence of SFD containing either a combination of five factors (3 μM CHIR99021, 10 ng/ml human FGF10, 10 ng/ml human FGF7, 10 ng/ml human BMP-4, and 50 nM ATRA), or three factors (3 μM CHIR99021 ...